Ethyl Pyruvate Ameliorates Hepatic Ischemia-Reperfusion Injury by Inhibiting Intrinsic Pathway of Apoptosis and Autophagy by Miao Shen, Jie Lu, Weiqi Dai, Fan Wang, Ling Xu, Kan Chen, Lei He, Ping Cheng, Yan Zhang, Chengfen Wang, Dong Wu, Jing Yang, Rong Zhu, Huawei Zhang, Yinqun Zhou, Chuanyong Guo

“…In this study, the purpose is to explore both the effect of ethyl pyruvate on hepatic I/R injury and regulation of intrinsic pathway of apoptosis and autophagy. …”
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Comparison of 1D and 3D volume measurement techniques in NF2-associated vestibular schwannoma monitoring by Isabel Gugel, Nuran Aboutaha, Bianca Pfluegler, Ulrike Ernemann, Martin Ulrich Schuhmann, Marcos Tatagiba, Florian Grimm

“…We retrospectively reviewed and used T1-weighted post-contrast enhanced (gadolinium) images for both SVA and linear measurements. 3D-SVA was performed manually or combined with semiautomated segmentation by using axial planes. …”
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Modifiable factors for irritable bowel syndrome: evidence from Mendelian randomisation approach by Jinling Tang, Zhirong Yang, Shanshan Wu, Feng Sha, Tengfei Lin, Di Liu, Meiling Cao, Yiwen Jiang, Weijie Cao, Fuxiao Li

“…Robust associations were found between multisite chronic pain and both IBS and coexisting disorders.Conclusions Our study identified a comprehensive array of potential modifiable factors and coexisting disorders associated with IBS, supported by genetic evidence, including genetic correlation and multiple MR analyses. …”
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Cross‐ethnicity face anti‐spoofing recognition challenge: A review by Ajian Liu, Xuan Li, Jun Wan, Yanyan Liang, Sergio Escalera, Hugo Jair Escalante, Meysam Madadi, Yi Jin, Zhuoyuan Wu, Xiaogang Yu, Zichang Tan, Qi Yuan, Ruikun Yang, Benjia Zhou, Guodong Guo, Stan Z. Li

“…RGB, Depth, infrared) tracks around this novel resource to boost research aiming to alleviate the ethnic bias. Both tracks have attracted 340 teams in the development stage, and finally, 11 and eight teams have submitted their codes in the single‐modal and multi‐modal face anti‐spoofing recognition challenges, respectively. …”
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Short-Term Activation of Peroxisome Proliferator-Activated Receptors α and γ Induces Tissue-Specific Effects on Lipid Metabolism and Fatty Acid Composition in Male Wistar Rats by Elin Strand, Vegard Lysne, Mari Lausund Grinna, Pavol Bohov, Asbjørn Svardal, Ottar Nygård, Rolf K. Berge, Bodil Bjørndal

“…In conclusion, short-term treatment with PPAR agonists induced tissue-specific effects on FA composition in liver and heart. Moreover, both PPARα and PPARγ activation lowered plasma TAG and phospholipids, most likely through effects on liver and adipose tissue, respectively. …”
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The effect of dietary fish oil replacement by microalgae on the gilthead sea bream midgut bacterial microbiota by Katsoulis-Dimitriou, Stefanos, Nikouli, Eleni, Gkalogianni, Elli Zafeiria, Karapanagiotidis, Ioannis T., Kormas, Konstantinos A.

“…It is well known that the gut microbiome and its interaction with the host influence several important factors for fish health such as nutrition and metabolism. …”
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Effect of Kind and Dosage of Enrichment Materials on the Nutritional Quality of Rotifers Especially n3-HUFA by Muhammad Agus Suprayudi

“…Rotifer enriched with EPA-TAG has a more complete of essential fatty acid profile compared to other enrichment materials due to their contained both of EPA and DHA. We conclude that rotifer enriched with EPA-TAG as enrichment material showed the best nutritional quality of rotifers from the stand point of essential fatty acid. …”
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Intestinal barrier function, caecal microbiota and growth performance of thermoneutral or heat stressed broiler chickens fed reduced crude protein diets supplemented with guanidino... by Reza Barekatain, Vivienne Inhuber, Nishchal Sharma, Tanya Nowland, Thi Thu Hao Van, Robert J. Moore, David Cadogan

“…The effectiveness of guanidinoacetic acid (GAA) in reduced protein (RP) diets on performance and gut health of broilers under heat stress is largely unknown. …”
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Beyond traditional metrics: evaluating the triglyceride-total cholesterol-body weight index (TCBI) in cardiovascular risk assessment by Mohsen Rezaee, Farzam Kamrani, Mobina Imannezhad, Hamed Hashemi Shahri, Waleed Khaled Saihood, Alireza Rezvani, Parsa Mearaji Far, Hanie Mahaki, Habibollah Esmaily, Mohsen Moohebati, Mohammad Shariati, Majid Ghayour-Mobarhan, Susan Darroudi

“…The primary outcomes evaluated include both the incidence and mortality rates associated with CVD. …”
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Immune response profiling of HERV-W envelope proteins in multiple sclerosis: potential biomarkers for disease progression by Stefano Ruberto, Stefano Ruberto, María I. Domınguez-Mozo, M. Angel Garcıa-Martınez, Davide Cossu, Davide Cossu, Leonardo A. Sechi, Leonardo A. Sechi, Roberto Alvarez-Lafuente

“…This study aims to evaluate both humoral and cell-mediated immune response to antigenic peptides derived from these proteins across different clinical forms and inflammatory phases of MS.MethodsIndirect enzyme-linked immunosorbent assay (ELISA) was employed to measure immunoglobulin G (IgG) responses to syncytin-1env 486-500 and pHERV-Wenv 486-504 peptides in MS patients. …”
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LC-MS/MS-based metabolomic study provides insights into altitude-dependent variations in flavonoid profiles of strawberries by Muhammad Junaid Rao, Muhammad Junaid Rao, Huaizheng Wang, Huaming Lei, Hongcha Zhang, Xiande Duan, Liuyuan Bao, Chengcui Yang, Duo Han, Yongzhi Zhang, Shunqiang Yang, Mingzheng Duan

“…These findings suggest that high-altitude cultivation conditions positively influence strawberry fruit characteristics, enhancing both bioactive compound profiles and overall fruit quality. …”
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Intraspecific variation for heat stress tolerance in wild emmer-derived durum wheat populations by Mohammed Yousif Balla, Mohammed Yousif Balla, Nasrein Mohamed Kamal, Nasrein Mohamed Kamal, Izzat Sidahmed Ali Tahir, Izzat Sidahmed Ali Tahir, Yasir Serag Alnor Gorafi, Yasir Serag Alnor Gorafi, Modather Galal Abdeldaim Abdalla, Hisashi Tsujimoto

“…The result showed that two families, developed from accessions of both northern and southern lineages exhibited high harvest index, elevated chlorophyll content, and reduced canopy temperature under heat stress. …”
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Are Artificial Sweeteners a Healthier Alternative to Sugar? by Julia Buszek, Piotr Czerniak, Adrianna Antoszewska, Weronika Bargiel, Dominika Bąk, Halszka Wajdowicz, Mateusz Warzocha, Michał Medygrał, Sylwia Buszek, Aldona Sokołowska, Maciej Rumian, Alicja Kosel

“…Some studies suggest possible changes in metabolism or gut microbiota, but evidence is inconclusive. Regulatory bodies like the FDA deem approved sweeteners safe within recommended daily limits. …”
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Oligodendrocyte precursor cell-derived exosomes combined with cell therapy promote clinical recovery by immunomodulation and gliosis attenuation by Sarah Ingrid Pinto Santos, Santiago José Ortiz-Peñuela, Alessandro de Paula Filho, Ana Laura Midori Rossi Tomiyama, Lilian de Oliveira Coser, Juliano Coelho da Silveira, Daniele dos Santos Martins, Adriano Polican Ciena, Alexandre Leite Rodrigues de Oliveira, Carlos Eduardo Ambrósio

“…Experimental therapy of C57BL/6 mice induced with experimental autoimmune encephalomyelitis (EAE) were grouped in control, treated with NSCs, treated with OPC-derived EVs and treated with a combination of both. The treatments were evaluated clinically using scores and body weight, microscopically using immunohistochemistry and immunological profile by flow cytometry. …”
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Oxidative Stress Induced Damage and Early Senescence in Preterm Placenta by Yudianto Budi Saroyo, Noroyono Wibowo, Rima Irwinda, Ani Retno Prijanti, Evy Yunihastuti, Saptawati Bardosono, Sofie Rifayani Krisnadi, Putri Indah Permata, Stephanie Wijaya, Victor Prana Andika Santawi

“…It is possible that critical telomere length has been achieved in both term and preterm placenta that warrants labor through senescence process. …”
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Augmentation with the inferior extensor retinaculum may facilitate earlier recovery in all-inside arthroscopic management of chronic lateral ankle instability by Xin Luo, Chong Xue, Yue Xue, Kai Fehske, Zi-He Zhang, Nicola Maffulli, Filippo Migliorini, Shi-Ming Feng

“…Conclusions For CLAI patients with arthroscopic grade 3 lesion of the ATFL, both the all-inside arthroscopic Broström-Gould procedure and the Broström procedure provide stability and enhance ankle joint function, resulting in similar functional outcomes at a 2-year follow-up. …”
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SiC free-standing membrane for X-ray intensity monitoring in synchrotron radiation beamlines by Gabriele Trovato, Marzio De Napoli, Christian Gollwitzer, Simone Finizio, Michael Krumrey, Francesco La Via, Luca Lanzanò, Giuliana Milluzzo, Samuele Moscato, Matthias Müller, Francesco Romano, Dario Ferreira Sanchez, Massimo Camarda

“…Silicon carbide (SiC) has recently emerged as an alternative to both materials, offering a high-quality mature semiconductor with high thermal conductivity and radiation hardness. …”
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Urinary human papillomavirus DNA as an indicator of gynaecological infection in young women in Schistosoma and HIV endemic South Africa by P. Pillay, H. N. Galappaththi-Arachchige, M. Taylor, B. Roald, B. Roald, E. F. Kjetland, E. F. Kjetland

“…The following associations were found using the Pearson Chi-Square and a Likelihood Ratio test: (a) between HIV positive status and urinary HPV DNA positive cases on both the urine (X2 = 5.007; p-value = 0.025) and (X2 = 4.264; p-value = 0.039) and between HIV positive status and CVL HPV DNA tests respectively (X2 = 5.165; p-value = 0.023) and (X2 = 4.321; p-value = 0.015), and (b) among urine HPV DNA and the CVL HPV DNA tests, where (X2 = 52.966; p-value = 0.001) and (X2 = 50.716; p-value = 0.001). …”
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Deleterious effects of thermal and water stresses on life history and physiology: a case study on woodlouse by Depeux, Charlotte, Branger, Angèle, Moulignier, Théo, Moreau, Jérôme, Lemaître, Jean-François, Dechaume-Moncharmont, François-Xavier, Laverre, Tiffany, Paulhac, Hélène, Gaillard, Jean-Michel, Beltran-Bech, Sophie

“…We tested independently the influences of increasing temperature and decreasing moisture on life history and physiological traits in the arthropod  Armadillidium vulgare. Both increasing temperature and decreasing moisture led reproductive success to decrease. …”
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Alpha 1-antitrypsin mitigates salt-sensitive hypertension in juvenile mice by reducing diacylglycerol concentrations and protein kinase C activity in kidney membranes by Yunus E. Dogan, Yunus E. Dogan, Yunus E. Dogan, Niharika Bala, Niharika Bala, Erika S. Galban, Erika S. Galban, Russell L. Lewis, Nancy D. Denslow, Sihong Song, Abdel A. Alli, Abdel A. Alli

“…Here, we hypothesized that administration of pharmaceutical-grade human AAT (hAAT) is effective in mitigating hypertension induced by salt-loading in juvenile mice by reducing the concentration of diacylglycerols (DAGs) and activity of protein kinase C (PKC) in the kidney.MethodsFour-week old 129Sv mice were salt-loaded to induce hypertension and then administered hAAT or vehicle.ResultsAdministration of hAAT was found to significantly reduce high blood pressure in both the active and inactive cycles of the 129Sv hypertensive mice. …”
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