Evaluation of the Level of Salivary sHLA-G in Children Aged 3–5 Years with or without Dental Caries by Mansoureh Bijani, Amrollah Mostafazadeh, Mina Motallebnejad, Ali Bijani, Roghiyeh Pourbagher, Samaneh Gharekhani

“…This analytic cross-sectional study was carried out on 83 healthy children aged 3 to 5 years of both genders, who were divided into three groups based on decayed dental surfaces (ds): group 1, caries-free children (CF, n = 29); group 2, children with 1 ≤ ds ≤ 3, 1 ≤ ds ≤ 4, and 1 ≤ ds ≤ 5 for age 3, 4, and 5 years, respectively (ECC, n = 20); and group 3, children with ds ≥ 4, ds ≥ 5, and ds ≥ 6 for age 3, 4, and 5 years, respectively (S-ECC, n = 34). …”
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Multi-ancestry genome-wide association analyses: a comparison of meta- and mega-analyses in the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study by Alan Kuang, Marie-France Hivert, M. Geoffrey Hayes, William L. Lowe, Denise M. Scholtens

“…Associations in this same region were identified using the mega-analysis pipeline, along with a well-documented association at MTNR1B on chromosome 11 with both fasting and 1-hr maternal glucose. For metabolomics analyses, the number of significant findings in the heterogeneous ancestry mega-analysis far exceeded those from the homogeneous ancestry meta-analysis and confirmed many previously documented associations, but genomic inflation factors were much more variable. …”
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Incidence and mortality of upper tract urothelial carcinoma in Korea: A nationwide population-based study conducted from 2002 to 2020 by Seongmin Moon, Yun-Sok Ha, Mina Kim, Hoseob Kim, Won Tae Kim, Yong-June Kim, Seok-Joong Yun, Sang-Cheol Lee, Ho Won Kang

“…There was a modest improvement in 5-year survival (both all cause- and cancer-specific) over the study period. …”
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Impact of Wetting-Drying Cycles on Soil Intra-Aggregate Pore Architecture Under Different Management Systems by Luiz F. Pires, Jocenei A. T. de Oliveira, José V. Gaspareto, Adolfo N. D. Posadas, André L. F. Lourenço

“…Regarding the pore shape, the greatest contribution to porosity and number of pores was due to triaxial-shaped pores for both 0 and 12 W-D cycles for all management practices. …”
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Development of Renal Failure without Proteinuria in a Patient with Monoclonal Gammopathy of Undetermined Significance: An Unusual Presentation of AL Kappa Amyloidosis by Yijuan Sun, Amarpreet Sandhu, Darlene Gabaldon, Jonathan Danaraj, Karen S. Servilla, Antonios H. Tzamaloukas

“…Renal biopsy is required to detect both the presence and the sites of deposition of renal AL kappa light chain amyloidosis.…”
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The Used of Paci-Paci Leaves Extract Leucas sp. to Prevent Mycotic Disease by Sri Nuryati, M.A. Suparman, Y. Hadiroseyani

“…One of alternative substances  can be used in both preventing and controlling safely is paci-paci, Leucas sp. …”
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Transcriptomic and functional characterization of megakaryocytic-derived platelet-like particles: impaired aggregation and prominent anti-tumor effects by Kaitlin Garofano, Vera Mariani, Kameron Rashid, Sumanun Suwunnakorn, Alfateh Sidahmed, Anelia Horvath, Sanjay B. Maggirwar, Travis J. O’Brien, Minoli A. Perera, Michael Whalen, Norman H. Lee

“…In contrast, PLP interactions with PCa cells inhibited both cell invasion and apoptotic resistance while failing to promote PLP aggregation. …”
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Development and design validation of a novel network meta-analysis presentation tool for multiple outcomes: a qualitative descriptive study by Lehana Thabane, Jason W Busse, Behnam Sadeghirad, Gordon H Guyatt, Mohit Bhandari, Romina Brignardello-Petersen, Fernando Kenji Nampo, Carlos A Cuello-Garcia, Raveendhara R Bannuru, Mark R Phillips, Yu Jia Guo, Sofia Bzovsky

“…Through an iterative process, we assessed the validity of both formats to maximise their clarity and ease of interpretation.Participants 26 participants including 20 clinicians who routinely provide patient care, 3 research staff/research methodologists and 3 residents.Main outcome measures Two team members used qualitative content analysis to independently analyse transcripts of all interviews. …”
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Bacteriophage and Phage-Encoded Depolymerase Exhibit Antibacterial Activity Against K9-Type <i>Acinetobacter baumannii</i> in Mouse Sepsis and Burn Skin Infection Models by Alexander I. Borzilov, Nikolay V. Volozhantsev, Olga V. Korobova, Lyubov V. Kolupaeva, Evgenia S. Pereskokova, Tatiana I. Kombarova, Mikhail M. Shneider, Konstantin A. Miroshnikov, Ivan A. Dyatlov, Anastasia V. Popova

“…In the mouse burn skin infection model, the number of <i>A. baumannii</i> cells on the surface of the wound and in the deep layers of the skin decreased by several-fold after treatment with both the K9-specific phage and the recombinant depolymerase. …”
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Clinical Outcomes of Critically Ill Patients Using Inhaled Nitric Oxide (iNO) during Intrahospital Transport by Leonid Koyfman, Omri Simchon, Anna Koyfman, Shoshana Mushaev, Benjamin F. Gruenbaum, Ron Gal, Michael Friger, Natan Arotsker, Alexander Zlotnik, Moti Klein, Evgeni Brotfain

“…We found that maximal iNO dosage during ICU stay, duration of mechanical ventilation, and percent of vasopressor support were the only independent risk factors for ICU mortality in both study groups. No difference in primary outcome of ICU mortality rate was found between the critically ill patients treated with iNO during intrahospital transportation and those who were treated with iNO but not transported during the ICU stay. …”
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Get it while it's hot: Benefits of a large herbivore exploiting stochastic resource pulses in a time of food scarcity by Samantha P. H. Dwinnell, Larissa T. Beumer, René van derWal, Steve D. Albon, Åshild Ø. Pedersen, Øystein Holand, Brage B. Hansen, R. Justin Irvine, Erik Ropstad, Vebjørn Veiberg, Leif Egil Loe

“…Reindeer that foraged most in marshes during autumn and early winter gained a positive carryover effect of up to 5 kg heavier body mass in late winter, with previously demonstrated benefits to both survival and reproduction. Marsh use was rare, brief, and intense, which is the expected response to a pulsed resource. …”
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Optimization of fermentation conditions to increase the production of antifungal metabolites from Streptomyces sp. KN37 by Xiaoyue Yang, Lijing Yuan, Muhammad Zeeshan, Chuntian Yang, Wen Gao, Guoqiang Zhang, Chunjuan Wang

“…In this study, we used the response surface method to optimize the fermentation medium and conditions of the strain KN37, for investigating the reasons for the enhanced biological activity at both the metabolic and transcriptomic levels. The results of the Plackett-Burman design showed that millet, yeast extract, and K2HPO4 were the key factors influencing its antifungal activity. …”
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Conventional type 1 dendritic cells in the lymph nodes aggravate neuroinflammation after spinal cord injury by promoting CD8+ T cell expansion by Li-Qing Wang, Xiao-Yi Wang, Yue-Hui Ma, Heng-Jun Zhou

“…The Basso Mouse Scale score of SCI mice was increased and the proportion of CD8+ T cells in blood and spinal cord tissue was decreased after FTY-720 injection. Both migratory cDC1s (CD103+) and resident cDC1s (CD8α+) were present in the LNs surrounding the injured spinal cord of SCI mice. …”
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Parsimonious versus extensive bleeding score: can we simplify risk stratification after percutaneous coronary intervention and reduce bleeding events by de-escalation of the antipl... by Pascal Vranckx, Stephan Windecker, Marco Valgimigli, Neil O’Leary, Yoshinobu Onuma, Peter Damman, Eva Christine Ida Woelders, Kai Ninomiya, Denise Adriana Maria Peeters, Arnoud Willem Johannes van 't Hof, Patrick Washington J C Serruys, Robert-Jan Matthijs van Geuns

“…Regression analysis showed that both methods predicted hazard for bleeding risk with HRs of 1.87 (95% CI: 1.59 to 2.18) and 2.67 (95% CI: 2.10 to 3.41) for the PRECISE-DAPT score and ZON-HR classification, respectively. …”
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Evaluation of Office and Ambulatory Central Blood Pressure and Augmentation Index by Two Methods and Their Changes After Lifestyle or Medical Interventions in Hypertension by Helga Gyöngyösi, Dóra Batta, Andrea László, Péter Torzsa, Beáta Kőrösi, Zsófia Nemcsik-Bencze, Orsolya Cseprekál, András Tislér, János Nemcsik

“…For the calculation of 24-h cSBP both systolic/diastolic and systolic/mean BP calibration methods were considered (24 h-cSBPC1 and 24 h-cSBPC2, respectively). …”
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Sensor-controlled fertigation management for higher yield and quality in greenhouse hydroponic strawberries by George Kerrigan Hutchinson, Lan Xuan Nguyen, Zilfina Rubio Ames, Krishna Nemali, Rhuanito Soranz Ferrarezi

“…This study aimed to compare various fertigation management strategies and, considering both yield and resource use, determine the optimal strategy for two newly released strawberry cultivars. …”
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Mind the G(ap): bridging prevention needs and approaches for GHB/GBL users and their social environment by Antonia Bendau, Lukas Roediger, Andrea Piest, Rüdiger Schmolke, Katharin Ahrend, Moritz Bruno Petzold, Twyla Michnevich, Felix Betzler

“…Perceptions and needs regarding prevention and harm-reduction, reasons and measures of decreasing use, and the impact of GHB/GBL/BD use were analyzed both quantitatively and qualitatively. Results Education, harm reduction strategies, and specialized support options were welcomed by users and non-users, while restrictive approaches were viewed negatively, particularly by heavy users. …”
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What should be publicly funded in the Colombian health system? A mixed methods study of citizens’ perceptions by Juan Carlos Velasquez, Claudia Marcela Vélez, Diana Patricia Díaz-Hernández, Pamela Velázquez-Salazar, Gilma Hernández-Herrera, Daniel Felipe Patiño-Lugo, Olga Francisca Salazar-Blanco, Leydi Camila Rodríguez-Corredor, Viviana María Vélez-Marín, Anny Julieth Jaramillo-García

“…We jointly interpreted both sets of findings.Results We identified two general approaches citizens used to consider public funding of healthcare technologies. …”
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Risk Factors for Incident Myopia among Teenaged Students of the Experimental Class of the Air Force in China by Lin-song Qi, Lu Yao, Xue-feng Wang, Jiu-mei Shi, Yong Liu, Teng-yun Wu, Zhi-kang Zou

“…Cycloplegic refraction was examined using retinoscopy in both eyes at the baseline and follow-up (3 years). …”
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Primary small cell carcinoma of the esophagus: Comparison between a Chinese cohort and Surveillance, Epidemiology, and End Results (SEER) data by Qin Xiao, Haifan Xiao, Shuyu Ouyang, Jinming Tang, Baihua Zhang, Hui Wang

“…Conclusions Although there are huge differences in the tumor characteristics and treatment modalities of SCCE between Chinese and U.S. patients, the prognosis of SCCE is equally poor in both. Surgery should be considered for patients with localized disease, while chemoradiotherapy is recommended for patients with regional and extensive disease.…”
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