Evaluation of the Effectiveness of Standard Precaution Training on Disposition of Occupational Blood Exposure Among Healthcare Trainees: A Pre-Post Intervention Study by Zhang X, Li H, Li N, Li Y, Kong L, Zhang M, Wang P, Ma Y, Ni L, Liu L, Meng X

“…The two groups taught the same knowledge using different methods. Both groups were tested the same content before and after the training.Results: The accuracy rates before and after training in different groups were 71.71% and 78.08%, respectively (P< 0.001). …”
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Early childhood deprivation and the impact of negative life events on mental health in later life: a test of the stress sensitization hypothesis by Jala Rizeq, Mark Kennedy, Kirellos Miseih, Wangjingyi Liao, Edmund J. S. Sonuga-Barke

“…For this analysis, data on emotional problems, autism, and disinhibited social engagement were used at both age 15 years and in early adulthood (23–25 years) using standardized questionnaire and interview measures. …”
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Breast cancer risk assessment based on a predictive model: evaluation of risk factors among Japanese women by Michiyo Yamada, Takashi Chishima, Takashi Ishikawa, Kazutaka Narui, Sadatoshi Sugae, Peter J. Tonellato, Itaru Endo

“…We developed accessible predictive models for Japanese women with optimal variables to evaluate risk factors for use by both medical institutions and women for primary BC prevention and to increase the BC screening rate. …”
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Orthorexia in Athletes: A Comprehensive Review of its Causes, Impact on Health, and Prevention Strategies by Kamila Fuczyło, Karolina Stankevič, Anna-Mariia Chernysh, Aleksandra Dusińska, Jakub Waszczyński, Justyna Woźniak, Justyna Weronika Kmieć, Wiktor Biesiada, Ewelina Kopczyńska, Piotr Kulej

“…Conclusions: ON poses significant risks to both health and performance in athletes. Early diagnosis and a multidisciplinary treatment approach that integrates psychotherapy, dietary counseling, and nutritional education are critical for managing ON. …”
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Oblique Lumbar Interbody Fusion Combined With Anterolateral Fixation and Cement Augmentation for the Treatment of Degenerative Lumbar Diseases in the Elderly Population: A Retrospe... by Weiqi Han, Lei He, Fei Wang, Xiaofeng Zhao, Cong Jin

“…In contrast, anterolateral fixation (AF) is less invasive but linked to higher subsidence rates. Ensuring both minimal invasiveness and adequate stability in OLIF‐assisted fixation remains a significant challenge. …”
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Association between serum uric acid levels and left ventricular hypertrophy based on electrocardiographic findings: a sex-specific analysis across cardiometabolic diseases by Anwar Ahmed Salim, Shin Kawasoe, Takuro Kubozono, Satoko Ojima, Satoshi Yamaguchi, Koji Higuchi, Yoshiyuki Ikeda, Hironori Miyahara, Koichi Tokushige, Mitsuru Ohishi

“…Furthermore, UA was associated with LVH in individuals without obesity, dyslipidemia, reduced kidney function, and diabetes in both sexes. Serum UA levels are associated with LVH in middle-aged women and men without cardiovascular disease risk, suggesting the potential role of UA as an LVH marker. …”
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Have crops already reached peak suitability: assessing global climatic suitability decreases for crop cultivation by Vhiny-Guilley Mombo, Mathilde Duvallet, Michiel Schaeffer, Florent Baarsch

“…Drainage could improve the optimal suitability area fivefold for maize and sorghum, while shading increases suitability for coffee (by up to 20% in both cases). The increased risk of food supply shortages led by climatic suitability loss may trigger increased deforestation if adaptation measures are not implemented.…”
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Unique pharmacological properties of etrasimod among S1P receptor modulators by Ibragim Gaidarov, H. Kiyomi Komori, Dariusz T. Stepniak, Karin Bruinsma, Huong Dang, Xiaohua Chen, Todd Anthony, Joel Gatlin, Lisa Karimi‐Naser, Anh‐Tuan Ton, Tim Indersmitten, Paul E. Miller, Andre Ghetti, Najah Abi‐Gerges, David Unett, Hussien Al‐Shamma, Christopher J. Rabbat, Catherine Crosby, John W. Adams

“…However, etrasimod was notably less potent than other S1PR modulators in assays measuring S1P1‐mediated G protein activation (GTPγS binding and cAMP inhibition). Relatively lower potency of etrasimod in inducing G protein signaling corresponded to significantly diminished activation of human cardiac G protein‐coupled inwardly rectifying potassium channels when compared to ozanimod. …”
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An In-depth Investigation of the Primordial Cluster Pair ASCC 19 and ASCC 21 by Qingshun Hu, Yuting Li, Mingfeng Qin, Chenglong Lv, Yang Pan, Yangping Luo, Shuo Ma

“…The clusters are separated by a 3D distance of 27.00 ± 7.51 pc. Both clusters share a common age (Log(age) = 6.95 ± 0.05), similar radial velocities (RV = 21.34 ± 4.47 km s ^−1 for ASCC 19 and RV = 20.05 ± 3.86 km s ^−1 for ASCC 21), and comparable metallicities ([Fe/H] = −0.14 ± 0.25 dex for ASCC 19 and [Fe/H] = −0.12 ± 0.04 dex for ASCC 21, from LAMOST-DR11). …”
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Impact of Year and Genotype on Benzoxazinoids and Their Microbial Metabolites in the Rhizosphere of Early-Vigour Wheat Genotypes in Southern Australia by Paul A. Weston, Shahnaj Parvin, Pieter-W. Hendriks, Saliya Gurusinghe, Greg J. Rebetzke, Leslie A. Weston

“…As previously reported, MBOA was detected frequently in both the rhizoplane and rhizosphere of wheat. Depending on the year and genotype, we also observed enhanced biotransformation of these metabolites to several microbially transformed aminophenoxazinones in the rhizosphere of many of the evaluated genotypes. …”
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Soluble CD14 Enhances the Response of Periodontal Ligament Stem Cells to Toll-Like Receptor 2 Agonists by Christian Behm, Alice Blufstein, Johannes Gahn, Nazanin Noroozkhan, Andreas Moritz, Xiaohui Rausch-Fan, Oleh Andrukhov

“…The production of IL-6, CXCL8, and CCL2 was gradually increased by both TLR-2 agonists and was significantly enhanced by sCD14. …”
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The β-Lactamase Gene Profile and a Plasmid-Carrying Multiple Heavy Metal Resistance Genes of Enterobacter cloacae by Chongyang Wu, Chaoqin Lin, Xinyi Zhu, Hongmao Liu, Wangxiao Zhou, Junwan Lu, Licheng Zhu, Qiyu Bao, Cong Cheng, Yunliang Hu

“…The complete genome of the blaMIR-positive strain (Y546) consisted of both a chromosome (4.78 Mb) and a large plasmid pY546 (208.74 kb). …”
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Molecular Characterization and Risk Factors of Carbapenem-Resistant Hypervirulent Klebsiella pneumoniae Isolated from Chinese Tertiary Hospital by Zhu R, Li J, Lian S, Li Y, Cai M, Cao Y, Xu X

“…Of these isolates, 54 (22.59%) carried both iucA and rmpA2, thus classifying them as CR-hvKp. …”
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Efficacy and safety of intermittent fasting for type 2 diabetes mellitus: A systematic review and meta-analysis of randomized trials by Joshua Chadwick, Lavanya Ayyasamy, Madhanraj Kalyanasundaram, Ganeshkumar Parasuraman, Bhavani Shankara Bagepally, Jeyashree Kathiresan, Lokesh Shanmugam

“…The frequency of hypoglycemic episodes was comparable across both groups. Interpretation &amp; conclusions: On the basis of moderate to low certainty of evidence, IF can be a safe dietary approach for patients with T2DM, with similar safety and effectiveness profiles to regular diets. …”
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Epidemiology, Disease Severity and Outcome of Severe Acute Respiratory Syndrome Coronavirus 2 and Influenza Viruses Coinfection Seen at Egypt Integrated Acute Respiratory Infection... by Manal Fahim, Wael H. Roshdy, Ola Deghedy, Reham Kamel, Amel Naguib, Shymaa Showky, Nancy Elguindy, Mohammad Abdel Fattah, Salma Afifi, Amira Mohsen, Amr Kandeel, Khaled Abdelghaffar

“…The hospitalization rate among patients coinfected with Flu-B and Flu A/H3 was 55.6 and 41.7%, with mean hospital days (8.0 ± 6 and 6.4 ± 6), pneumonia infection (40.0 and 80.0%), ICU admission (40.0 and 26.7%), and death (20.0% for both), while no patients hospitalized with A/H1. …”
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Colorectal Serrated Neoplasia: An Institutional 12-Year Review Highlights the Impact of a Screening Programme by A. J. McCarthy, S. M. O’Reilly, J. Shanley, R. Geraghty, E. J. Ryan, G. Cullen, K. Sheahan

“…Over a 149-month period, 759 “serrated adenoma” polyps were identified, with 664 (from 523 patients) available for review. 41.1% were reviewed by both pathologists; 15.1% (100/664) were reclassified, with the majority being changed from SSL/P to hyperplastic polyp (HYP) (66/664; 9.9%). 80.3% of these HYPs were located in the left colon, and the majority exhibited prolapse effect. …”
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Study on the comparison between Bosentan and Macitentan in the treatment of persistent pulmonary hypertension of the newborns, simultaneously on sildenafil: A randomized double-bli... by Mandana Kashaki, Arash Mohazzab, Mohammad Radgoudarzi, Arash Bordbar, Sama Dabbagh

“…No mortality case occurred. SPAP was reduced in both Bosentan and Macitenan groups with the mean difference in SPAP of 9 (95% CI: 7.34–10.65) in Bosentan and SPAP mean difference of 14 (95% CI: 12.12–15.86) in Macitentan group. …”
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Real-world clinical utility of Xpert MTB/RIF Ultra in the assessment of tuberculosis in a low-TB-incidence, high-resource setting by Robert C Free, Manish Pareek, Hemu Patel, Pranabashis Haldar, Jee Whang Kim, Richard Halliwell, Nelun Perera, Gerrit Woltmann, Alison Glimour-Caunt, Raman Verma

“…Incorporating Xpert-Ultra with culture increased microbiologically verified diagnosis to 91.7% for PTB and 75.9% for extrapulmonary TB, compared with 85.0% and 44.8%, using culture alone. In PTB, both smear and Xpert-Ultra grade were positively associated with the proportion of contacts testing QFT positive. …”
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Genome-Wide Identification and Expression Analysis of PkNRT Gene Family in Korean Pine (<i>Pinus koraiensis</i>) by Xinyu Zhao, Haibo Wu, Boyang Li, Pengyang Wang, Peng Zhang, Hailong Shen, Jianfei Yang

“…Furthermore, a significantly greater number of lateral roots was observed in seedlings under nitrogen-deficient conditions, accompanied by an increase in both total root biomass and root length. The temporal expression profiles of 16 <i>PkNRTs</i> in seedling roots revealed that four <i>PkNRTs</i>, <i>PkNPF5.6</i>, <i>PkNPF5.13</i>, <i>PkNPF6.1</i>, and <i>PkNPF6.2</i>, exhibited significantly upregulated expression under the NO₃⁻ deficiency condition, whereas robust induction was observed for <i>PkNPF1.1</i>, <i>PkNRT2.6</i>, and <i>PkNRT3.3</i> upon the NO₃⁻ sufficiency condition. …”
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Bp-13 PLA2: Purification and Neuromuscular Activity of a New Asp49 Toxin Isolated from Bothrops pauloensis Snake Venom by Georgina Sucasaca-Monzón, Priscila Randazzo-Moura, Thalita Rocha, Frank Denis Torres-Huaco, Augusto Vilca-Quispe, Luis Alberto Ponce-Soto, Sérgio Marangoni, Maria Alice da Cruz-Höfling, Léa Rodrigues-Simioni

“…In the mouse phrenic nerve-diaphragm (PND) preparation, the time for 50% paralysis was concentration-dependent (P<0.05). Both the replacement of Ca2+ by Sr2+ and temperature lowering (24°C) inhibited the Bp-13 PLA2-induced twitch-tension blockade. …”
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