Validated UPLC-MS/MS Method for Determination of Futibatinib and Its Pharmacokinetics in Beagle Dogs by Heng Li, Hao-Zhe Ding, Yi-Lin Wang, Feng Zhang, Ya-Hao Song, Xiang-Jun Qiu

“…Under the positive ion condition of an electrospray spray ion (ESI+) source, multireaction detection was used, and the ion pairs for futibatinib and IS were m/z 418.99 ⟶ 295.97 and 468.96 ⟶ 382.00, respectively. Futibatinib had a good linear relationship in the linear range of 0.5∼100 ng/mL; the lower limit of quantification (LLOQ) was 0.5 ng/mL. …”
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Human neural stem cell–derived extracellular vesicles protect against ischemic stroke by activating the PI3K/AKT/mTOR pathway by Jiayi Wang, Mengke Zhao, Dong Fu, Meina Wang, Chao Han, Zhongyue Lv, Liang Wang, Jing Liu

“…Finally, we showed that human neural stem cell–derived extracellular vesicles have a good in vivo safety profile. Therefore, human neural stem cell–derived extracellular vesicles are a promising potential agent for the treatment of ischemic stroke.…”
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Oxidative stress and DNA lesions: the role of 8-oxoguanine lesions in Trypanosoma cruzi cell viability. by Pedro H N Aguiar, Carolina Furtado, Bruno M Repolês, Grazielle A Ribeiro, Isabela C Mendes, Eduardo F Peloso, Fernanda R Gadelha, Andrea M Macedo, Glória R Franco, Sérgio D J Pena, Santuza M R Teixeira, Leda Q Vieira, Alessandra A Guarneri, Luciana O Andrade, Carlos R Machado

“…These characteristics make 8-oxoG a good cellular biomarker to indicate the extent of oxidative stress. …”
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Cochlear Implantation in Charcot-Marie-Tooth Disease: Case Report and Review of the Literature by C. Lane Anzalone, Sarah Nuhanovic, Amy P. Olund, Matthew L. Carlson

“…Upon initial activation 3 weeks after surgery, the patient reported excellent access to sound in the cochlear implant-only condition. He has made good progress at each subsequent visit; speech perception testing after seven months showed improvement from 0% to 32% on AzBio sentence and 53% on CNC phoneme testing in the cochlear implant-only condition. …”
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Effect of trauma center operation on emergency care and clinical outcomes in patients with traumatic brain injury by Han Kyeol Kim, Yoon Suk Lee, Woo Jin Jung, Yong Sung Cha, Kyoung-Chul Cha, Hyun Kim, Kang Hyun Lee, Sung Oh Hwang, Oh Hyun Kim

“…Results On comparing the entire TBI patient population via dividing them into the aforementioned two groups, the following results were found in the group of patients who visited the hospital after the operation of the trauma center: an increased number of patients with a good functional prognosis (P<0.001 and P=0.002, respectively), an increased number of surviving discharges (P<0.001 and P<0.001, respectively), and a reduction in overall emergency care time (P<0.05, for all item values). …”
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Functional Profile of Enzymatic Hydrolysates in Food Proteins by Svetlana N. Lebedeva, Bulat A. Bolkhonov, Sesegma D. Zhamsaranova, Bayana A. Bazhenova, Svetlana Yu. Leskova

“…The native egg and soy proteins demonstrated good allergenic properties, and the DTH response index increased fivefold. …”
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Analisis risiko operasional di PT asuransi umum x by ML Denny Tewu, Timothy Victory T

“…Hasil penelitian berdasarkan pendekatan atas 5 pilar dalam Good Corporate Governance (GCG) menunjukkan bahwa ada 5 kejadian yang tidak diharapkan, yaitu: Karyawan tidak paham SOP dan target perusahaan (Transparency), Tidak adanya sistem pengendalian internal yang effective (Accountability), Tidak mengikuti aturan yang ada (Responsibility), Tidak adanya diversifikasi bisnis  (Independency), Belum jelasnya karier path untuk pegawai dengan kinerja bagus (Fairness)…”
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‘Underestimation of fall risks by older adults: The need for professional evaluation to identify home hazards’ by E．Y Ishigaki, A．S Passos, L．E．G Leme

“…In the test-retest analysis, only nine items showed good agreement. Still, the second assessment revealed higher scores, suggesting improved risk perception due to a potential educational effect of the initial evaluation. …”
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Maternal and Perinatal Outcomes in Teenage Versus Adult Pregnancies – A Prospective Comparative Study by Prathima S, Sarojini -, Ashakiran T R, Manasa K, Bhanu BT

“…Maternal and perinatal morbidity and mortality can be minimized in teenage pregnancies by providing education improving their nutritional status socioeconomic status educating them about contraception safe sex practices to avoid unintended pregnancies and by providing them good antenatal care.…”
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An Investigation Towards Resampling Techniques and Classification Algorithms on CM1 NASA PROMISE Dataset for Software Defect Prediction by Agung Fatwanto, Muh Nur Aslam, Rebbecah Ndugi, Muhammad Syafrudin

“…In the context of classification models, ensemble-based algorithms, which extend the decision tree classification mechanism such as Random Forest and eXtreme Gradient Boosting, achieved sufficiently good performance for predicting defective software modules. …”
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Development and validation of an integrated model for the diagnosis of liver cirrhosis with portal vein thrombosis combined with endoscopic characters and blood biochemistry data:... by Jie Yang, Xu Zhang, Jia Chen, Xianghong Hou, Minghong Shi, Longlong Yin, Longchun Hua, Cheng Wang, Xiaolong Han, Shuyan Zhao, Guolan Kang, Ping Mai, Rui Jiang, Hongwei Tian

“…The calibration curve, decision and clinical impact curves showed the model demonstrated a good predictive accuracy and clinical benefits. The validation got an AUC of 0.890 (95% CI, 0.831–0.934), A nomogram tool was finally established for application.Conclusion Blood test combined endoscopic characters could preliminarily predict the liver cirrhosis with portal vein thrombosis for cirrhotic patients undergoing endoscopic examination.…”
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Strain Monitoring of Combustible Gas Implosion Test Based on Fiber Bragg Grating by Lei Gao, Qinghua Zhang, Erbing Li, Yangyang Sun, Zhenglin Zhang, Shikun Pu, Xiejun Cheng, Fengjuan Rong

“…FBGs have excellent sensing performance, such as long life, antielectromagnetic interference, easy networking, and good reusability. In this paper, FBG sensors are applied to strain monitoring in ethylene flammable implosion experiments. …”
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STRATEGI PENGEMBANGAN PARIWISATA DI SEPANJANG SUNGAI KAPUAS KOTA PONTIANAK by RISKA APRILIA AYUNINGTYAS, SRI HIDAYATI DJOEFFAN

“…For example, in Pontianak itself, has a very good nature and attractive to tourists due to the attraction still original, exotic and diverse. …”
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Percutaneous paravertebral endoscopic decompression for the treatment of far-out syndrome involving the L5 nerve root: technical report and preliminary results by Fei Yang, Chaoqun Feng, Ke Li, Xiaohong Fan, Rigao Chen

“…According to the modified MacNab criteria, excellent or good outcomes were observed in 15 cases (93.70%). …”
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Comparative effectiveness of liquid and freeze-dried vaccines for oral vaccination of dogs against rabies by Z. D. Yershebulov, A. T. Zhunushov, Zh. T. Amanova

“…The virus neutralizing antibodies observed in the immunized dogs ensured good protection from virulent CVS strain. All animals of the control group died after infection demonstrating clinical signs of paralytic rabies. …”
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Biodegradation of Azo and disperse dyes by Trametes versicolor: Process optimization and MnP enzyme dynamics by Isma Fayyaz, Salina Saddick, Raja Tahir Mahmood, Muhammad Javaid Asad, Muhammad Altaf Hussain, Jiandong Hu, Muhammad Awais, M. Ijaz Khan, Shaxnoza Saydaxmetova

“…The MnP of T. versicolor is quite active (Vmax= 60.24 mM/mL/min) ligninolytic enzyme and has good affinity for guaicol (Km=8.58 µM).…”
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Effect of Form on Radiation Absorption in Ab Anbar Domes of Hot and Arid and Cold Climate Using Honeybee & ladybug Plugins by tohid shiri, Mohammad Didehban, Mohsen Taban

“…In the past, architects in many parts of Iran had built traditional public buildings to create a community convenience and comfort. Ab Anbars are good example of this facility structures which they were suppose to collect water in rainy condition and keep it cool for use in dry condition of year espacialy in hot and arid climate. …”
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Study for the Effect on Structure and Properties of Highland Barley Proteins During Stir-frying by HUANG Liang-liang, JIANG Kang-hui, LI Qi, YANG Jie, HU Yun, LI Liang

“…The trends of G' and G" values of the protein solution were consistent before and after frying; besides, with the increase in angular frequency, the tan δ value was gradually greater than 1, and the internal microstructure of the protein solution changes at high angular frequency, which may resulted in phase transition and exhibit good viscosity. In summary, frying can change the protein structure of highland barley, and partially alter the properties.…”
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HPV vaccination knowledge, attitude, and practices among physicians in a teaching hospital, Karachi by Sehrish Habib Memon, Bhombhal Swaleha Tariq

“…In terms of knowledge, 67.2% physicians showed good knowledge. In terms of attitude, it was found that 90.9% of physicians showed positive attitude toward prescribing HPV vaccine. …”
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Practice, Knowledge, and Attitude of Health Care Providers regarding Cancer Pain Management: A National Survey by Jinmei Liu, Ming Zhang, Juan Luo, Jiyi Xie, Xu Chen, Hanxiang Wang, Shijun Li, Shengli Yang, Chunfen Peng, Liangle Yang, Bin Deng, Yu Zhang, Cong Wang, Jianli Hu, Chen Shi

“…Hierarchical analysis showed that passing a good pain management (GPM) ward program and participating in advanced training had positive impacts on the scores of all three parts in the three professions (ptrend <0.05). …”
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