A dual-RPA based lateral flow strip for sensitive, on-site detection of CP4-EPSPS and Cry1Ab/Ac genes in genetically modified crops by Jinbin Wang, Yu Wang, Xiuwen Hu, Yifan Chen, Wei Jiang, Xiaofeng Liu, Juan Liu, Lemei Zhu, Haijuan Zeng, Hua Liu

“…In conclusion, this strategy achieved the expected purpose of simultaneous detection of the two popular targets in GM crops within 20 min at 37 ℃ in a rapid, equipment-free field manner, providing a new alternative for rapid screening for transgenic assays in the field.…”
Get full text

Efficacy of carbonyl cyanide-3-chlorophenylhydrazone in combination with antibiotics against Mycobacterium abscessus by Jifang Zheng, Qiang Liu, Haoran Wang, Fengmin Huo, Junnan Jia, Hairong Huang, Suting Chen

“…ABSTRACT Given the intrinsic resistance of Mycobacterium abscessus to a wide range of conventional antibiotics, it is urgent to explore new therapeutic approaches to manage this infection effectively. …”
Get full text

The clinical-stage drug BTZ-043 accumulates in murine tuberculosis lesions and efficiently acts against Mycobacterium tuberculosis by Andreas Römpp, Axel Treu, Julia Kokesch-Himmelreich, Franziska Marwitz, Julia Dreisbach, Nadine Aboutara, Doris Hillemann, Moritz Garrelts, Paul J. Converse, Sandeep Tyagi, Sina Gerbach, Luzia Gyr, Ann-Kathrin Lemm, Johanna Volz, Alexandra Hölscher, Leon Gröschel, Eva-Maria Stemp, Norbert Heinrich, Florian Kloss, Eric L. Nuermberger, Dominik Schwudke, Michael Hoelscher, Christoph Hölscher, Kerstin Walter

“…BTZ-043 is a novel antibiotic showing good bactericidal activity in humans in a phase IIa trial. …”
Get full text

A harmonized dataset relating alternative farmer management practices to crop yield, soil organic carbon stock, nitrous oxide emissions, and nitrate leaching generated using IPCC m... by Roberta Calone, Angela Fiore, Guido Pellis, Maria Luz Cayuela, Gabriele Mongiano, Alessandra Lagomarsino, Simone Bregaglio

“…However, these methods often do not explicitly account for the combined effects of management practices on carbon and nitrogen cycles or productivity, as this is not required for national GHG inventories. Here we present a new dataset featuring 1.8 Mln of agronomic case scenarios, i.e., unique combinations of farming practices and pedoclimatic conditions, which have been associated with values of SOC changes, nitrous oxide emissions, nitrate-nitrogen leaching, and crop yield. …”
Get full text

The potential mechanism of Isodon suzhouensis against COVID-19 via EGFR/TLR4 pathways by Hong Duan, Wei Wang, Shu Li, Han Li, Ghulam Jilany Khan, Yong Ma, Fawang Liu, Kefeng Zhai, Henggui Hu, Zhaojun Wei

“…Corona Virus Disease 2019 (COVID-19) has brought the new challenges to scientific research. Isodon suzhouensis has good anti-inflammatory and antioxidant stress effects, which is considered as a potential treatment for COVID-19. …”
Get full text

High-performance 2D electronic devices enabled by strong and tough two-dimensional polymer with ultra-low dielectric constant by Qiyi Fang, Kongyang Yi, Tianshu Zhai, Shisong Luo, Chen-yang Lin, Qing Ai, Yifan Zhu, Boyu Zhang, Gustavo A. Alvarez, Yanjie Shao, Haolei Zhou, Guanhui Gao, Yifeng Liu, Rui Xu, Xiang Zhang, Yuzhe Wang, Xiaoyin Tian, Honghu Zhang, Yimo Han, Hanyu Zhu, Yuji Zhao, Zhiting Tian, Yu Zhong, Zheng Liu, Jun Lou

“…To address these challenges, new low-k dielectric (k < 2) materials need to be developed to replace current silicon dioxide (k = 3.9) or SiCOH, etc. …”
Get full text

Design of multifunctional interfaces on ceramic solid electrolytes for high-performance lithium-air batteries by Yunxin Shi, Ziyang Guo, Changhong Wang, Mingze Gao, Xiaoting Lin, Hui Duan, Yonggang Wang, Xueliang Sun

Get full text

Ultrasound-guided percutaneous microwave ablation of primary hyperthyroidism: security and efficacy analysis by Jing-E Zhu, Chun-Jun Sheng, Hui-Li Zhang, Jia-Xin Li, Xiao-Wan Bo, Jia-Jing Yin, Peng Yang, Song-Yuan Yu, Li-Ping Sun

“…., were observed during our follow-up.Conclusion Ultrasound-guided MWA for reducing thyroid gland volume in primary hyperthyroidism patients is a new, safe, and effective minimally invasive treatment method that is a good choice for patients who cannot or refuse traditional treatment methods.…”
Get full text

3D-QSAR, design, molecular docking and dynamics simulation studies of novel 6-hydroxybenzothiazole-2-carboxamides as potentially potent and selective monoamine oxidase B inhibitors by Dong Xie, Dong Xie, Yongzheng Tian, Li Cao, Penghang Guo, Penghang Guo, Zhibiao Cai, Jie Zhou

“…Finally, the binding stability and dynamic behavior of these compounds with MAO-B receptors were analyzed by molecular dynamics simulation (MD).ResultsThe 3D-QSAR model showed good predictive ability, with a q2 value of 0.569, r2 value of 0.915, SEE of 0.109 and F value of 52.714 for the COMSIA model. …”
Get full text

5-aminolevulinic acid in photodynamic therapy used in dermatology as a method of treating acne vulgaris. by Karolina Sacher, Krystyna Zabojska, Aleksandra Cygnarowicz, Mariola Turemka, Negar Hosseinnejad, Aneta Klaudia Wojtas, Mikołaj Biskupski, Urszula Korotko, Kinga Witowska, Aneta Mandziuk

“…Photodynamic therapy with 5-ALA acid may also serve as a good complementary treatment to other substances. …”
Get full text

Development and validation of a multidimensional, culturally and socially inclusive Child Resilience Questionnaire (parent/caregiver report) to measure factors that support resilie... by Deirdre Gartland, Elisha Riggs, Rebecca Giallo, Stephanie Janne Brown, Karen Glover, Kelsey Hegarty, Amanda Mitchell, Jane Yelland, Josef Szwarc, Sue Casey, Donna Weetra, Mardi Stowe, Sharon Mongta, Helen Herman, Selena White, Tanya Koolmatrie, Georgie Paxton

“…It has good psychometric properties and will have broad applications in clinical, educational and research settings. …”
Get full text

Seasonal variations and comparative nutritional composition of hatchery-reared, hatchery-released, and wild black rockfish (Sebastes schlegelii) by Liu Wang, Liu Wang, Yunhai He, Xu Wei, Xinyan Liang, Xinyan Liang, Ruonan Zhang, Ruonan Zhang, Qi Liu, Qi Liu, Chenqi Wang, Chenqi Wang, Jinfeng Chen, Jinfeng Chen, Meiyuan Li, Meiyuan Li, Zhi Ma, Shaodong Qu

Get full text

Use of thymidine kinase 1 autoantibody, thymidine kinase antigen, extracellular protein kinase A autoantibody, and C‐reactive protein for early detection of malignant tumors in dog... by Yoonhee Kim, Wonhee Lee, Byunggak Kim, Bonghwan Jang, Kyung‐Rok Yu, Hong Sook Kim, Minok Ryu, Yein Oh, Kyoungwon Seo, Chul Park, Ulsoo Choi, Dongha Bhang, Hwayoung Youn

Get full text

Rehabilitation using virtual gaming for Hospital and hOMe-Based training for the Upper limb in acute and subacute Stroke (RHOMBUS II): results of a feasibility randomised controlle... by Cherry Kilbride, Tom Butcher, Meriel Norris, Nana Anokye, Alyson Warland, Karen Baker, Dimitrios A Athanasiou, Guillem Singla-Buxarrais, Jennifer Ryan, Francesca Gowing, Elmar Kal, Carole Pound, Victoria Stewart, Basaam Aweid, Arul Samiyappan

“…Recruitment, training and support were manageable and completion of data was good, indicating that a future randomised controlled trial would be feasible.Trial registration number ISRCTN11440079.…”
Get full text

Comparison of centrifugal-membrane hybrid plasmapheresis and centrifugation therapeutic plasma exchange in hyperlipidemia by ZHANG Bin, WU Chunxi, ZHOU Yumeng, ZHOU Fang, YI Zhongmei

“…[Objective] To establish a new centrifugal-membrane hybrid plasmapheresis (CMHP) model, and observe its clinical efficacy, safety and advantages in the treatment of hyperlipidemia by comparing with centrifugation therapeutic plasma exchange (cTPE). …”
Get full text

Editorial by Ann-Kristin Kölln, Antony Mason, Maria Lenk, Jörg Tremmel, Markus Rutsche

“… Among the many headlines that followed the 2018 midterm elections in the United States, one stood out as very good news for political representation: the election of Alexandria Ocasio-Cortez. …”
Get full text

Presenting a merit-oriented service compensation system model for veterans in sports by Hoseain Aeinehchi, Mohammad reza Esmaeilzadeh Ghandehari, Hoseain peymanizad, Hasan Fahim Davin

“…The findings of the research showed that the research model has a good fit with the collected data. Also, in order to improve the fit indices of the model, the terms suggested in accordance with the research literature were used and finally the research model was confirmed, and the GOF value is equal to 0.62 which shows a strong fit to the model.Extended abstractIntroductionThe importance of world's current developments such as economic competition and the increasing growth of global competition (Yazdani et al, 2020), the emergence of conflict and tension between governments (Goby et al, 2015), and the consequences of critical events obliged many governments and organizations in the last decade to reform their human resource management systems, which necessitates adopting new approaches and changing the mentality of senior government managers in human resource management policies such as reward and compensation, recruitment, selection and promotion (Noti Zahi et al., 2022).Service compensation is one of the main elements of the employment relationship between individuals and organizations, and in addition to being the largest operational cost for many organizations, it is considered as a tool to increase organizational performance and sustainable competition (Ivana et al, 2019). …”
Get full text

Analisis Sentimen Kebijakan Penerapan Kurikulum Merdeka Sekolah Dasar dan Sekolah Menengah pada Media Sosial Twitter dengan Menggunakan Metode Word Embedding dan Long Short Term Me... by Alif Rizal Maulana, Satrio Hadi Wijoyo, Yusi Tyroni Mursityo

“…This new policy certainly brings in many opinions from various parties, one of which is students who are directly affected by this curriculum. …”
Get full text

Clinical study on the treatment of chronic heart failure with a novel D‐shant atrium shunt device by Xiaoke Shang, Mei Liu, Yucheng Zhong, Xueli Wang, Song Chen, Xiaojuan Fu, Ming Sun, Mingxing Xie, Yuhe Ke, Ying Guan, Changdong Zhang, Nianguo Dong

“…Heart function was evaluated by New York Heart Association functional class. Echocardiography was used to measure the diameter of the new chamber and ventricle, and to evaluate the degree of mitral and tricuspid regurgitation. …”
Get full text