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    Goal-Directed vs Traditional Approach to Intraoperative Fluid Therapy during Open Major Bowel Surgery: Is There a Difference? by Prabhu P. Sujatha, Anitha Nileshwar, H. M. Krishna, S. S. Prasad, Manjunath Prabhu, Shobha U. Kamath

    Published 2019-01-01
    “…This study prospectively compared goal-directed intraoperative fluid therapy with traditional fluid therapy in general surgical patients undergoing open major bowel surgery. …”
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    Linking One Health to 3R. Culture of Care as a bridge towards Russell and Burch's highest goal: Replacement by Katharina Ameli, Eva Raimann, Jaqueline Krüger, Stephanie Krämer

    Published 2024-08-01
    “…However, this expansion can lead to contradictions, such as the emphasis on reproducibility, which implies the continued use of animals and thus conflicts with the original highest goal of the 3Rs, replacement. At the same time, the Culture of Care approach associated with the 3Rs promotes a change in the human-animal relationship but has not significantly challenged the use of animals in research. …”
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