<i>Salmonella enterica</i> serovar Schwarzengrund: Distribution, Virulence, and Antimicrobial Resistance by Monique A. Felix, Jing Han, Bijay K. Khajanchi, Yasser M. Sanad, Shaohua Zhao, Steven L. Foley

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两种植骨材料促进即刻种植体周骨组织再生效果比较 by 邓飞龙, 马建元, 简裕涛, 罗智斌, 刘臣汉, 吴伟良

“…【目的】比较两种植骨材料PepGen P15 Flow（简称P15）和Bio-Oss引导即刻种植体周骨组织再生能力及骨一种植体结合能力。…”
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Detection of CRISPR‒Cas and type I R–M systems in Klebsiella pneumoniae of human and animal origins and their relationship to antibiotic resistance and virulence by Xue Li, Ling Wang, Jinghuan Lin, Yingjuan Gu, Zhihua Liu, Jing Hu

“…However, a lower prevalence of most antibiotic-resistance genes was found when the CRISPR‒Cas systems were alone, and when type I R-M systems were coexisting, some of the antibiotic resistance gene incidence rates were even lower (quinolones, macrolides, tetracyclines and carbapenems), and some of them were higher instead (aminoglycosides, clindamycins, rifampicin-associated, sulfonamides, methotrexates, beta-lactamases and ultrabroad-spectrum beta-lactamases). …”
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Diversity Assessment of Some Sesame (Sesamum indicum L.) Genotypes Cultivated in Northern Ghana Using Morphological and Simple Sequence Repeat (SSR) Markers by Raphael Adu-Gyamfi, Ruth Prempeh, Issahaku Zakaria

“…Twenty-one out of the 38 primers were polymorphic. Cluster analyses using the Euclidean similarity test and a complete link clustering method were used to make a dendrogram out of the morphological data. …”
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Causal role of plasma liposome in diabetic retinopathy: mendelian randomization (MR) study by Kai Yin, Lu Ding, Xueyan Li, Yuqi Zhang, Siyu Song, Liyuan Cao, Ruixue Deng, Min Li, Zirui Li, Qinjing Xia, Daqing Zhao, Xiangyan Li, Zeyu Wang

“…The robustness of our findings was assessed using leave-one-out and funnel plots. To further assess the reliability of the results, linkage disequilibrium score regressions, colocalization analysis and reverse MR analysis were also performed. …”
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基于泛基因组学和消减蛋白质组学挖掘新型抗诺卡氏菌药物靶点 by 黎尔彤, 苏雅琳, 刘文彬, 金小宝

“…近年来发现诺卡氏菌对常用药物已产生耐药性，因此，挖掘新抗诺卡氏菌药物靶点、开发新药物具有迫切需求。方法取GenBank数据库中31株诺卡氏菌的全基因组序列，利用BPGA进行泛基因组学分析，利用消减蛋白组学筛选药物靶点。…”
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人血管内皮生长因子165慢病毒载体的构建及其抗放射所致细胞凋亡的作用

“…【目的】 构建人血管内皮生长因子165(hVEGF165)慢病毒表达载体pCDH-CMV-MCS-EF1-copGFPhVEGF165,并转染至HT22 细胞,并进一步观察其对放射线损伤所致的细胞凋亡的保护作用【方法】 PCR扩增hVEGF165基因,克隆到pCDH-CMV-MCS-EF1-copGFP载体;通过酶切电泳,菌落PCR初步筛选和测序鉴定构建的pCDH-CMV-MCS-EF-GFP1-hVEGF165重组载体;采用磷酸钙共转染法转染293T细胞包装制备慢病毒液,并感染HT22细胞,采用实时RT-PCR及Western Blot检测hVEGF165基因在HT22细胞中的表达情况进一步对单纯HT22细胞空质粒转染组以及hVEGF165转染组HT22细胞进行0510 Gy的X线照射,流式细胞仪检测细胞凋亡情况【结果】 hVEGF165基因片段重组到pCDH-CMV-MCS-EF1-copGFP载体,酶切后电泳结果显示均能得到与理论大小相符的片段,测序结果与GenBank序列完全一致,转染HT22后hVEGF mRNA及蛋白表达水平明显增高而且同各对照组相比,hVEGF165可以降低细胞放疗后的凋亡率【结论】 pCDH-CMV-MCS-EF1-copGFP-hVEGF165 慢病毒表达载体构建成功,其转染HT22细胞后可获得高水平hVEGF165 mRNA和蛋白的表达,hVEGF165具有抗放射所致细胞凋亡的作用…”
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D型肉毒毒素灭鼠剂对棕背雪雀危害机理的试验研究 by 李生庆, 李淑萍, 胡国元, 雷萌桐, 韩生义, 刘成录, 王林业

“…结果显示:棕背雪雀对D型肉毒毒素的敏感性介于高原鼢鼠与青海田鼠之间,LD₅₀为2.71万～3.16万MLD/kg(95%可信限为1.69万～4.88万MLD/kg); 大白鼠胃肠内容物对D型肉毒毒素的破坏强度明显高于高原鼠兔及棕背雪雀; 在基因编码区序列推导的氨基酸序列水平上,棕背雪雀体内的VAMP1氨基酸序列(GenBank No.GQ905710)与昆明系小鼠完全相同,VAMP1氨基酸序列在第48号氨基酸位点(为48M型,而非48Ⅰ型)属于D型肉毒毒素敏感型氨基酸,表明棕背雪雀对D型肉毒毒素具有一定的敏感性,在现地鼠害防治中应精准控制鼠药投放剂量,建议采取药物警戒色趋避鸟类食毒饵。…”
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黑熊苦味受体Tas2R2基因的分子克隆与序列分析 by 钟 源 潘 阳 侯文海 姚永芳 徐怀亮 张栓玲

“…实验采用PCR和克隆测序方法首次从黑熊基因组中获得一全长为1 019 bp的苦味受体Tas2R2基因DNA序列(GenBank登录号:JQ239035)。该序列含有完整的1个外显子(无内含子),大小为915 bp,编码304个氨基酸残基。…”
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Association of antihypertensive drug target genes with alzheimer’s disease: a mendelian randomization study by He Zheng, Chaolei Chen, Yingqing Feng

“…Exposure was derived from existing eQTL data in blood from the eQTLGen consortium and in the brain from the PsychENCODE and subsequently replicated in GTEx V8 and BrainMeta V2. We performed two-sample Mendelian randomization (MR) to estimate the potential effect of different antihypertensive drug classes on AD using summary statistics from a meta-analysis (111,326 cases and 677,663 controls) and further replicated in FinnGen cohorts (9301 cases and 367,976 controls). …”
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Multidrug Resistant Enteric Bacteria from Cancer Patients Admitted in Douala Laquintinie Hospital, Littoral Region of Cameroon by Michael F. Kengne, Ornella D. Tsobeng, Ballue S. T. Dadjo, Victor Kuete, Armelle T. Mbaveng

“…Most isolates were sensitive to imipenem (IMP), gentamicin (GEN), and amikacin (AMK). Proteus vulgaris, the most prevalent isolate, showed significantly high resistance (with p<0.05) in cancer patients compared to noncancer patients at amoxicillin/clavuranic acid (AMC) (89.13% versus 41.30%), ceftriaxone (CTR) (63.04% versus 39.13%), ciprofloxacin (CIP) (65.22% versus 34.18%), and tetracycline (TET) (93.48% versus 63.04%). …”
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Optimization and characterization studies of poultry waste valorization for peptone production using a newly Egyptian Bacillus subtilis strain by Hajar Saeed, Anthony Ragaey, Ziad Samy, Viola Ashraf, Aly ElMostafa, Norhan Ahmad, Enjy Bebawy, Nour ElHoda M. Sorour, Salwa M. El-Sayed, Ashraf Bakry, Naglaa Ebeed, Hesham Elhariry, Thanaa El-Noby, Samah H. Abu-Hussien

“…The isolation process yielded the highly potent proteolytic B.subtilis isolate P6, identified through 16S rRNA gene sequencing to share 94% similarity with the B.subtilis strain KEMET024 (GenBank accession number PP694485.1) and deposited in MIRCEN culture collection, Cairo, Egypt as EMCC 998871. …”
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Yield performance, adaptability and processing qualities of pre-release potato clones under different Rwandan agro-ecologies by Rukundo Placide, Ndacyayisenga Theophile, Elke Vandamme, Nshimiyimana Jean Claude, Mendes Thiago

“…Across all sites for both seasons, the clones CIP393077.159, CIP393371.58, and CIP393280.64 revealed the yields of 31, 28. and 27 tons/ha that fall in the same range of yields as local checks Kinigi and Kirundo with 30 and 35 tons/ha, respectively. …”
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Immunoinformatics Approach for Multiepitope Vaccine Prediction from H, M, F, and N Proteins of Peste des Petits Ruminants Virus by Bothina B. M. Gaafar, Sumaia A. Ali, Khoubieb Ali Abd-elrahman, Yassir A. Almofti

“…The sequences of the immunogenic proteins were retrieved from GenBank of the National Center for Biotechnology Information (NCBI). …”
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Mendelian Randomization Reveals Potential Causal Relationships Between DNA Damage Repair-Related Genes and Inflammatory Bowel Disease by Zhihao Qi, Quan Li, Shuhua Yang, Chun Fu, Burong Hu

“…The GWAS summarized data for IBD and its two subtypes, Crohn’s disease (CD) and ulcerative colitis (UC), were acquired from the FinnGen study. We elected from genetic variants located within or near 2000 DDR-related genes in cis, which are closely associated with DDR-related gene changes. …”
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La frontière comme espace liminal by Marie-Christine Fourny

“…L’analyse du projet d’élaboration d’une stratégie macro-régionale pour les Alpes en donne une illustration. Ce projet vise en effet à unir un espace « Alpes » autour d’objectifs communs. …”
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Peran Forum Koordinasi Pencegahan Terorisme dalam Menjalankan Program Deradikalisasi by Mohamad Rapik, Bunga Permatasari, Adinda Farah Anisya

“…Diawali dari asumsi bahwa FKPT merupakan agen penting dalam melakukan deradikalisasi, maka penelitian ini berupaya menyorot kinerja dan hasil yang telah dicapai oleh lembaga ini. …”
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Introduction of Eucalyptus spp. into the United States with Special Emphasis on the Southern United States by R. C. Kellison, Russ Lea, Paul Marsh

“…Introduction of Eucalyptus spp. into the United States from Australia on a significant scale resulted from the gold rush into California in 1849. Numerous species were evaluated for fuel, wood products, and amenity purposes. …”
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Insulinomas: Comprehensive Review of Epidemiology, Pathophysiology, Clinical Manifestations, Diagnostic Approaches, and Treatment Options by Joanna Rychlewska-Duda, Justyna Lisiecka, Mateusz Janik, Barbara Ufnalska, Anna Konarska, Artur Fabijański, Anna Machowiak, Michał Nowak, Wojciech Firlej, Adriana Daria Dukacz

“…Insulinomas can be sporadic or associated with Multiple Endocrine Neoplasia Type 1 (MEN-1) syndrome, a genetic disorder caused by mutations in the MEN1 gene. …”
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Du roman merveilleux-scientifique et de son action sur l’intelligence du progrès by Maurice Renard

“…C’est en ce sens qu’il a « pour objet, d’amener le lecteur à une contemplation de l’univers plus proche de la vérité. »…”
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