Efficacy and Safety of Transdermal Buprenorphine versus Oral Tramadol/Acetaminophen in Patients with Persistent Postoperative Pain after Spinal Surgery by Jae Hyup Lee, Jin-Hyok Kim, Jin-Hwan Kim, Hak-Sun Kim, Woo-Kie Min, Ye-Soo Park, Kyu-Yeol Lee, Jung-Hee Lee

“…Adults with persistent postoperative pain (Numeric Rating Scale [NRS] ≥ 4 at 14–90 days postsurgery) were enrolled. Patients received once-weekly BTDS (n=47; 5 μg/h titrated to 20 μg/h) or twice-daily TA (n=40; tramadol 37.5 mg/acetaminophen 325 mg, one tablet titrated to 4 tablets) for 6 weeks. …”
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Exploring therapeutic mechanisms of Chuan Huang Fang-II in the treatment of acute kidney injury on chronic kidney disease patients from the perspective of lipidomics by Ling Chen, Qian Wang, Tonglu Li, Lejia Li, Chen Wang, Bing Xu, Xuezhong Gong

“…Objective This study aims to assess the clinical efficacy and safety of CHF-II in combination with RG for treating AKI on CKD (A on C), and to explore potential therapeutic mechanisms through lipidomics analysis.Methods 98 patients were enrolled and randomly assigned to the RG or RG + CHF groups. …”
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Lateral Ventricular Volume Asymmetry and Optic Nerve Sheath Diameter Predict Intracranial Pressure in Traumatic Brain Injury Patients by Yang Wang, Ziming Yuan, Zuoyan Zhang, Jiawei Shang, Mingna Li, Wei Wang

“…A prospective observational study was conducted in the patients admitted to our department between October 2018 and October 2020. 20 patients with moderate-severe TBI with a Glasgow Coma Scale of 3–12 were enrolled. Lateral ventricle volume (LVV) value measurements were conducted using ITK-SNAP software. …”
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Ketamine Use in Hysterosalpingography (the Jimah Procedure): A Follow-Up of Bilateral Tubal Evaluation of 27 Infertile  Women  at a Teaching Hospital, Ghana by Bashiru Babatunde Jimah, Anthony Baffour Appiah, Benjamin Dabo Sarkodie, Dorothea Anim

“…A total of 27 patients (age range: 25–48 years) previously diagnosed of bilateral tubal blockage or spasm were enrolled for the repeat HSG procedure. The median age was 34 years (IQR: 32–37), while secondary infertility (20) (74.1%) was the commonest indication. …”
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Angiotensin receptor neprilysin inhibition versus individualized RAAS blockade: design and rationale of the PARALLAX trial by Rolf Wachter, Sanjiv J. Shah, Martin R. Cowie, Peter Szecsödy, Victor Shi, Ghionul Ibram, Ziqiang Zhao, Jianjian Gong, Sven Klebs, Burkert Pieske

“…BMIC includes (i) enalapril, (ii) valsartan, and (iii) placebo depending on the type of medical therapy prior to enrolment. The primary endpoints are the change in plasma NT‐proBNP concentration from baseline to 12 weeks and the change from baseline in 6MWD distance at 24 weeks. …”
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Fatigue in patients with chronic obstructive pulmonary disease: protocol of the Dutch multicentre, longitudinal, observational FAntasTIGUE study by Mirjam A G Sprangers, Martijn A Spruit, Emiel F M Wouters, Daisy J A Janssen, Jean W M Muris, Judith B Prins, Yvonne M J Goërtz, Milou Looijmans, Melissa S Y Thong, Jeannette B Peters, Chris Burtin, Yvonne Meertens-Kerris, Arnold Coors, Jan H Vercoulen

“…This manuscript describes the protocol of the FAntasTIGUE study and gives an overview of the possible strengths, weaknesses and clinical implications.Methods and analysis A 2-year longitudinal, observational study, enrolling 400 patients with clinically stable COPD has been designed. …”
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Concepciones del profesorado sobre el uso educativo del patrimonio by Belén CASTRO-FERNÁNDEZ, Leticia CASTRO-CALVIÑO, Jorge CONDE-MIGUÉLEZ, Ramón LÓPEZ-FACAL

“…Participan en el estudio 76 docentes en activo de las etapas de infantil, primaria y secundaria, pertenecientes a 20 centros educativos de la provincia de A Coruña (Galicia). …”
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Increased IL-21 Expression Induces Granzyme B in Peripheral CD5+ B Cells as a Potential Counter-Regulatory Effect in Primary Sjögren’s Syndrome by Gábor Papp, Edit Gyimesi, Krisztina Szabó, Éva Zöld, Margit Zeher

“…Thirty-two pSS patients and 24 healthy controls were enrolled in our study. We investigated the expression of intracellular GrB and IL-21 receptor (IL-21R) of CD19+CD5+ and CD19+CD5− B cells; furthermore, we determined the IL-21 expression of iNKT cells as well. …”
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Profile of Endothelin-1, Nitric Oxide, and Prostacyclin Levels in Pulmonary Arterial Hypertension Related to Uncorrected Atrial Septal Defect: Results from a Single Center Study in... by Lucia Kris Dinarti, Anggoro Budi Hartopo, Dyah Wulan Anggrahini, Ahmad Hamim Sadewa, Budi Yuli Setianto, Abdus Samik Wahab

“…Forty-four subjects were enrolled in this study. Endothelin-1 level and mPAP had significant moderate positive correlation (r = 0.423 and p value = 0.004). …”
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Efficacy Of Triamcinolone Injection In Management Of Oral Lichen Planus by Humera Iqbal, Uzair Luqman, Kanwal Zulfiqar, Zarnab Rizwan, Mobina Fatima Zulfiqar

“…Method: This study was conducted in the Department of Oral & Maxillofacial Surgery, Kahuta Research Laboratories Islamabad. 100 patients who fulfilled the inclusion-exclusion criteria were selected. All the enrolled patients were treated with intralesional TA injection once a week for 4 weeks. …”
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Propuestas para afrontar la despoblación desde lo local y la relevancia de los mecanismos de desarrollo neo-endógeno: el caso de Andalucía (España) by Francisco Antonio Navarro Valverde, Alberto Capote Lama, Laura Porcel Rodríguez, Eugenio Cejudo García

“… La consideración del conocimiento y experiencia de las comunidades rurales es clave para afrontar la despoblación. Dentro de este marco es necesario sistematizar buenas y malas praxis, extrayendo enseñanzas de éstas, conocer la relevancia que otorgan a determinadas acciones públicas, y abundar en las propuestas que se proponen desde las comunidades afectadas. …”
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Diagnostic Value of Interferon-Gamma Release Assays Combined with Multiple Indicators for Tuberculous Peritonitis by Xidong He, Yuanxue Gao, Qi Liu, Zhifang Zhao, Wanhang Deng, Hong Yang

“…A total of 180 patients with suspected tuberculous peritonitis were enrolled, and 24 were excluded. 73 patients with a confirmed diagnosis of tuberculous peritonitis were included in the tuberculous peritonitis group, 83 patients with other diseases in the other-disease control group, and 52 healthy individuals in the control group. …”
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Compasión y Empatía: Emocionalización en el Sistema Penal Juvenil Uruguayo by Cecilia Montes Maldonado, Laura López-Gallego, Marina Medan

“…Utilizamos los datos construidos en un estudio de caso de enfoque etnográfico desarrollado en centros que ejecutan medidas judiciales privativas de libertad (2016-2020). …”
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Immunogenicity of the 9-valent human papillomavirus vaccine: Post hoc analysis from five phase 3 studies by Anna R. Giuliano, Joel M. Palefsky, Stephen E. Goldstone, Jacob Bornstein, Ilse De Coster, Ana María Guevara, Ole Mogensen, Andrea Schilling, Pierre Van Damme, Corinne Vandermeulen, Misoo C. Ellison, Susan Kaplan, Jianxin Lin, Rachael Bonawitz, Alain Luxembourg

“…Post hoc analyses of 9-valent human papillomavirus (9vHPV) vaccine immunogenicity were conducted in five Phase 3 studies that enrolled males. Month 7 antibody geometric mean titers (GMTs) after three 9vHPV vaccine doses were analyzed in 10,024 males/females aged 16–26 years from studies 001 (NCT00543543), 002 (NCT00943722), 003 (NCT01651949), and 020 (NCT02114385). …”
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Educational Migration in Russian Regions: Statistical Approach by E. A. Pitukhin, O. A. Zyateva, L. V. Shchegoleva, V. E. Sokolov

“…The main indicator of educational migration was selected as a statistical indicator – the share of students from the total enrollment who received a previous education in another subject of the Russian Federation. …”
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Mindfulness-based retreat for mothers of paediatric heart transplant recipients: protocol for a pilot intervention study by Sara Ahola Kohut, Joanna Mitchell, Samantha J Anthony, Taylor Robertson, Heather Telfer, Mirna Seifert-Hansen

“…Informed consent will be obtained prior to participant enrolment. Findings will be disseminated via conference presentations and submitted for publication in a peer-reviewed journal.…”
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Meta Analysis of Efficacy and Safety of Prostate Biopsy: A Comparison Between Transperineal and Transrectal Approach by Syah Mirsya Warli, Stivano Rizky Valentino Torry, Dhirajaya Dharma Kadar, Ginanda Putra Siregar, Fauriski Febrian Prapiska

“…A total of 19 publications, involving 80133 patients with suspicion of prostate cancer who underwent prostate biopsy, were enrolled in the analysis. The pooled estimate demonstrated no significant differences in the cancer detection rate between TR and TP (risk difference (RD)=0.03; 95% CI: −0.01 to 0.08; P = .12). …”
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Automatic three-dimensional reconstruction of the oesophagus in achalasia patients undergoing POEM: an innovative approach for evaluating treatment outcomes by Alanna Ebigbo, Helmut Messmann, Vivian Grünherz, Miriam Elia, Alessandra Brunner, Tamara Krafft, Leo Pöller, Pia Schneider, Fabian Stieler, Bernhard Bauer, Anna Muzalyova, Sandra Nagl

“…In addition, these values were compared with normal value indices of non-achalasia patients.Results 50 treatment-naive achalasia patients were enrolled prospectively. The mean TE index decreased significantly (p<0.0001) and the mean LES index increased significantly 3 months post-POEM (p<0.0001). …”
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Repeatability and Agreement of Central Corneal Thickness and Keratometry Measurements between Four Different Devices by Laszlo Kiraly, Jana Stange, Kathleen S. Kunert, Saadettin Sel

“…Fifty-five healthy eyes from 55 volunteers were enrolled in this study. CCT (IOLMaster 700, Pentacam HR, and Cirrus HD-OCT) and keratometry readings (IOLMaster 700, Pentacam HR, and iDesign) were measured. …”
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Medical Student Musculoskeletal Knowledge: Examining the Impact and Value of an Orthopaedic Surgery Clerkship Using the Freedman and Bernstein Examination by Nicole Nishime, Mary Seibel, Dieter Lindskog, Daniel Wiznia

“…Methods Medical students enrolled in the orthopaedic surgery clerkship between February 2019 and May 2024 were asked to participate in pre- and post-clerkship surveys using the Freedman and Bernstein Basic Cognitive Musculoskeletal Examination. …”
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