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  1. 3881

    A New Prognostic Indicator of Immune Microenvironment and Therapeutic Response in Lung Adenocarcinoma Based on Peroxisome-Related Genes by Zhen Xiong, Liwen Zhang, Wei Fan

    Published 2022-01-01
    “…However, the prognostic values of peroxisome-related genes (PRGs) were rarely reported. Genomic sequence, mutation, and clinical data of 535 LUAD tissues were obtained from TCGA data sets. …”
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  2. 3882
  3. 3883

    Comparative analysis of antibiotic resistance genes between fresh pig manure and composted pig manure in winter, China. by Shuai Huang, Minghui Xing, Haifeng Wang

    Published 2025-01-01
    “…The gut microbiome acts as a reservoir for numerous antibiotic resistance genes (ARGs), which influence both existing and future microbial populations within a community or ecosystem. …”
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  4. 3884

    Gene Expression Profiling in Lungs of Chronic Asthmatic Mice Treated with Galectin-3: Downregulation of Inflammatory and Regulatory Genes by Esther López, M. Paz Zafra, Beatriz Sastre, Cristina Gámez, Carlos Lahoz, Victoria del Pozo

    Published 2011-01-01
    “…Results. We identify a set of genes involved in different pathways whose expression is coordinately decreased/increased in mice treated with Gal-3 gene therapy. …”
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  5. 3885
  6. 3886

    Feature Selection in Cancer Classification: Utilizing Explainable Artificial Intelligence to Uncover Influential Genes in Machine Learning Models by Matheus Dalmolin, Karolayne S. Azevedo, Luísa C. de Souza, Caroline B. de Farias, Martina Lichtenfels, Marcelo A. C. Fernandes

    Published 2024-12-01
    “…Gene expression data from RNA-seq, extracted from The Cancer Genome Atlas (TCGA), were used to train ML models, including decision trees (DTs), random forest (RF), and XGBoost (XGB), which achieved accuracies of 98.69%, 99.82%, and 99.37%, respectively. …”
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  7. 3887

    Exploring Core Genes Associated with Sepsis and Systemic Inflammatory Response Syndrome Using Single-Cell Sequencing Technology by Shen Y, Leng L, Hu Y

    Published 2025-02-01
    “…The frequency of occurrence is on the rise, but there is a lack of certain indicators for the timely detection and recognition of illnesses.Methods: By virtue of scRNA-seq, this research has analyzed single-cell transcriptome data from samples taken from groups with septic death and systemic inflammatory response syndrome so as to identify the unique markers and patterns in immune response.Results: By revealing the status of twelve cell clusters of four major cell types in blood samples through UMAP cell clustering and the differences of major cell populations between the dead and SIRS patients, the results have elucidated the components of different cells and their marker genes in two disease states, and the response mechanism beneficial to disease diagnosis in blood samples.Conclusion: By establishing a theoretical framework centered on cellular and molecular regulation, the study has introduced a novel approach for diagnosing and treating sepsis death group and SIRS patients early, as well as differentiating and preventing these conditions.Keywords: sepsis, SIRS, single cell sequencing, biomarkers, single cell transcriptome…”
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  8. 3888

    Parameterized High-Precision Finite Element Modelling Method of 3D Helical Gears with Contact Zone Refinement by Yanping Liu, Yongqiang Zhao, Ming Liu, Xiaoyu Sun

    Published 2019-01-01
    “…In order to perform a tooth contact analysis of helical gears with satisfactory accuracy and computational time consuming, a parameterized approach to establish a high-precision three-dimension (3D) finite element model (FEM) of involute helical gears is proposed. …”
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  9. 3889

    PPARγ Regulates Genes Involved in Triacylglycerol Synthesis and Secretion in Mammary Gland Epithelial Cells of Dairy Goats by Hengbo Shi, Jun Luo, Jiangjiang Zhu, Jun Li, Yuting Sun, Xianzi Lin, Liping Zhang, Dawei Yao, Huaiping Shi

    Published 2013-01-01
    “…To explore the function of PPARγ in the goat mammary gland, we cloned the whole cDNA of the PPARγ gene. Homology alignments revealed that the goat PPARγ gene is conserved among goat, bovine, mouse, and human. …”
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  10. 3890

    Fasting Upregulates PPAR𝛼 Target Genes in Brain and Influences Pituitary Hormone Expression in a PPAR𝛼 Dependent Manner by Bettina König, Christine Rauer, Susann Rosenbaum, Corinna Brandsch, Klaus Eder, Gabriele I. Stangl

    Published 2009-01-01
    “…Here we demonstrate that fasting of rats increased mRNA concentrations of typical PPAR𝛼 target genes implicated in 𝛽-oxidation of fatty acids (acyl-CoA oxidase, carnitine palmitoyltransferase-1, medium chain acyl-CoA dehydrogenase) and ketogenesis (mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase) in pituitary gland and partially also in frontal cortex and diencephalon compared to nonfasted animals. …”
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  12. 3892

    Characterization and molecular detection of pathogenicity and antibiotic resistance genes in Vibrio parahaemolyticus isolated from Pacific white shrimp by Muhammad Arif Mulya, Fachriyan Hasmi Pasaribu, Usamah Afiff, Munti Yuhana

    Published 2022-07-01
    “…However, no resistance was shown to CIP, ENR, and CHL. The PCR-based analysis resulted a detectable resistance gene of ampC (42% of the isolates) and tetB (83% of the isolates). …”
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  13. 3893

    ADAMTS1, CRABP1, and NR3C1 Identified as Epigenetically Deregulated Genes in Colorectal Tumorigenesis by Guro E. Lind, Kristine Kleivi, Gunn I. Meling, Manuel R. Teixeira, Espen Thiis-Evensen, Torleiv O. Rognum, Ragnhild A. Lothe

    Published 2006-01-01
    “…Background: Gene silencing through CpG island hypermethylation is a major mechanism in cancer development. …”
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  17. 3897

    The effect of drought stress on Pinellia ternata in terms of physiology and aquaporin genes after Arbuscular mycorrhizal fungal inoculation by Shuang Li, Yajun Liu, Han He, Yike Xu, Xiaochun Sun, Wenjing Huang

    Published 2025-02-01
    “…Mycorrhization upregulated the expression of PtTIP, NIP, and PIP genes under drought stress. AMF can alleviate drought stress-induced damage by regulating photosynthetic capacity, osmosis, antioxidant activities, and aquaporin gene expression. …”
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  18. 3898

    Eucalyptus grandis WRKY genes provide insight into the role of arbuscular mycorrhizal symbiosis in defense against Ralstonia solanacearum by Jianlang Zhang, Xinzhu Yang, Chunyu Huo, Xinyi Fan, Qiutong Liu, Zhihong Liu, Yu Su, Zujing Chen, Zujing Chen

    Published 2025-02-01
    “…IntroductionWRKY transcription factors are essential for plant growth, health, and responses to biotic and abiotic stress.MethodsIn this study, we performed a deep in silico characterization of the WRKY gene family in the genome of Eucalyptus grandis. …”
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  19. 3899

    Identification of Proteins and Genes Associated with Hedgehog Signaling Pathway Involved in Neoplasm Formation Using Text-Mining Approach by Nadezhda Yu. Biziukova, Sergey M. Ivanov, Olga A. Tarasova

    Published 2024-03-01
    “…For recognition of the Hedgehog pathway proteins and genes and neoplastic diseases we use a dictionary-based named entity recognition approach, while for all other proteins and genes machine learning method is used. …”
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