Longitudinal associations between air pollution and incident dementia as mediated by MRI-measured brain volumes in the UK Biobank by Rhiannon Thompson, Xinning Tong, Xueyi Shen, Jinjun Ran, Shengzhi Sun, Xiaoxin Iris Yao, Chen Shen

“…Methods: UK Biobank is a large long-term study of 500,000 adults enrolled from 2006 to 2010 age 40–69 years. ICD-10 classified reports of dementia cases up to 2022 (Alzheimer’s disease, vascular dementia, dementia in other classified diseases, and unspecified dementia) were identified from health record linkage. …”
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Análise do comportamento com relação ao isolamento social da população de Itaqui – RS by Dieison Morozoli da Silva, Taináh Espinosa, Kellen da Rosa Carlosso, Felipe Batista Ethur, Luciana Zago Ethur

“…Isso demonstra que, mesmo em uma cidade distante de grandes centros urbanos, a tensão sobre um tema tão preocupante atinge a maioria da população. …”
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Las ciencias sociales como integración de saberes en la dimensión humana by Joaquín Molano Barrero

“…Esta intencionalidad surge debido a las dificultades que han padecido las ciencias sociales dentro del paradigma científico de la modernidad. …”
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Evaluation of B cell related markers and autoantibodies in rheumatoid arthritis patients treated with abatacept by Ting Wang, Natalia V. Giltiay, Christian Lood, Ning Wang, Bobby Kwanghoon Han

“…ObjectivesTo investigate whether biomarkers related to B cell activation and autoantibody production are associated with the response to abatacept in rheumatoid arthritis (RA) patients.MethodsTwenty-five patients with RA were enrolled in this study. Responders (n=10) to abatacept were subjects who achieved ACR50 response at week 24. …”
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Acquired hypothyroidism, iodine status and hearing impairment in adults: A pilot study. by Tereza Grimmichova, Ludmila Verespejova, Zuzana Urbaniova, Martin Chovanec, Martin Hill, Radovan Bilek

“…<h4>Methods</h4>30 patients with untreated and newly diagnosed peripheral hypothyroidism (H) and a control group of 30 healthy probands (C) were enrolled in the study. Biochemical markers were measured, including median iodine urine concentrations (IUC) µg/L. …”
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Migraine and subsequent chronic kidney disease risk: a nationwide population-based cohort study by Ming-Ju Wu, Chew-Teng Kor, Chia-Chu Chang, Shuo-Chun Weng, Chia-Lin Wu, Ping-Fang Chiu, Der-Cherng Tarng

“…Objective We compared the incidence and risk of chronic kidney disease (CKD) between subjects with new-onset migraine and matched controls without migraine in this large-scale retrospective cohort study.Design Population-based cohort study.Setting 8880 subjects with migraine and 503 070 subjects without migraine were enrolled between January 1, 2000 and December 31, 2013, all diagnosed to be without kidney disease. …”
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Low transthyretin is associated with the poor prognosis of colorectal cancer by Zhe Zhang, Zhe Zhang, Zhe Zhang, Chenhao Hu, Chenhao Hu, Chenhao Hu, Feiyu Shi, Feiyu Shi, Feiyu Shi, Lei Zhang, Lei Zhang, Lei Zhang, Ya Wang, Ya Wang, Yujie Zhang, Yujie Zhang, Yujie Zhang, Xiaojiang Zhang, Xiaojiang Zhang, Xiaojiang Zhang, Junjun She, Junjun She, Junjun She

“…Furthermore, an additional cohort of 377 CRC patients enrolled between January 2014 and December 2015 was included as an external validation.ResultsBased on the optimal cut-off value of 121.3 mg/L, we divided the patients into the TTR-lower group (&lt;121.3 mg/L) and the TTR-higher group (≥121.3 mg/L). …”
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Biomarkers of pembrolizumab efficacy in advanced anal squamous cell carcinoma: analysis of a phase II clinical trial and a cohort of long-term responders by Jeffrey A Meyerhardt, Sunil Kumar, Jessica A Zerillo, Aparna Parikh, James M Cleary, Scott Rodig, Benjamin Schlechter, Kimmie Ng, Stephanie K Dougan, Nora Horick, Glenn J Hanna, Andrew L Coveler, Anuj K Patel, Nadine J McCleary, Douglas A Rubinson, Jeffrey W Clark, Kent Mouw, Kathleen Pfaff, Thomas A Abrams, Matthew B Yurgelun, Eliezer M Van Allen, S Jennifer Wang, Leah H Biller, Harshabad Singh, Emma L Welsh, Brandon M Huffman, Lestat R Ali, Megan T Hoffman, Katherine A Metayer, Shayla Murray, Alexandra Bird, Jennifer A Chan, Wolfram Goessling, Jeffrey S Wisch, Brendan Reardon, Robert J Mayer, Catherine Del Vecchio Fitz, Charlotte Kuperwasser

“…Background Recent trials suggest that programmed cell death 1 (PD-1)-directed immunotherapy may be beneficial for some patients with anal squamous cell carcinoma and biomarkers predictive of response are greatly needed.Methods This multicenter phase II clinical trial (NCT02919969) enrolled patients with metastatic or locally advanced incurable anal squamous cell carcinoma (n=32). …”
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Lymphocyte-C-reactive protein ratio upon admission to predict disease progression and ICU admission in adult patients with diabetic ketoacidosis by Yi-Jia Hu, Shu-Xiao Qiu, Jian-Nan Zhang, Qi-Qi Lai, Yi-Lu Lin, Lin-Qiong Liu, Di Wu, Hui-Ying Liu, Huan Meng, Jia-Xi Xu, Jia-Ning Zhang, Bo-Wen Liu, Yan Gao, Kai Kang, Yang Gao

“…A total of 271 adult DKA patients were enrolled and categorized into three groups: mild group (n = 42), moderate group (n = 64), and severe group (n = 165). …”
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Metagenomics and Faecal Metabolomics Integrative Analysis towards the Impaired Glucose Regulation and Type 2 Diabetes in Uyghur-Related Omics by Rebiya Nuli, Jureti Azhati, Junxiu Cai, Aizhatiguli Kadeer, Bing Zhang, Patamu Mohemaiti

“…A total of 60 different glycemic Uyghur subjects were enrolled and divided into T2DM, IGR, and normal glucose tolerance (NGT) groups. …”
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Cross-sectional association between plasma aldosterone concentration and cognitive performance by mini-mental state examination in community dwellers by Aketilieke Nusufujiang, Mulalibieke Heizhati, Nanfang Li, Ling Yao, Wenbo Yang, Hui Wang, Mei Li, Lin Gan, Adalaiti Maitituersun, Miaomiao Liu, Qiaolifanayi Nuermaimaiti, Li Cai, Xiayire Aierken, Xiufang Li, Qin Luo, Jing Hong

“…Therefore, we aimed to explore whether PAC is associated with cognitive performance in this population.MethodsWe cross-sectionally enrolled adults using multistage random sampling from Emin, China in 2019. …”
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Risk Factors of Hypertension among Diabetic Patients from Yaoundé Central Hospital and Etoug-Ebe Baptist Health Centre, Cameroon by Beryl Kemche, Brice Ulrich Saha Foudjo, Elie Fokou

“…A hospital-based cross-sectional study was conducted for 6 months, and 109 participants (types 1 and 2), aged 24–81 years, were enrolled using simple random sampling. A pretested structured questionnaire was used to collect sociodemographic data, habitual behaviors, clinical history blood pressure, and anthropometric measures. …”
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Acute Kidney Injury Complicating Critical Forms of COVID-19: risk Factors and Prognostic Impact [version 3; peer review: 2 approved] by Ghadhoune Hatem, Yosra Yahia, Olfa Hammami, Hend Allouche, Insaf Trabelsi, Jihene Guissouma, Hana Ben Ali

“…Methods A retrospective descriptive case/control monocentric study conducted in a medical intensive care unit of a tertiary teaching hospital over a period of 18 months. Results We enrolled 144 patients, with a mean age of 58±13 years old and a male predominance (sex-ratio: 1.25). …”
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Analysis of Retinal Perfusion in Children, Adolescents, and Young Adults with Type 1 Diabetes Using Optical Coherence Tomography Angiography by Chiara Mameli, Alessandro Invernizzi, Alice Bolchini, Giorgio Bedogni, Elisa Giani, Maddalena Macedoni, Gianvincenzo Zuccotti, Chiara Preziosa, Marco Pellegrini

“…Fifty-three patients (median age 15.5, IQR 12.4-19.4 years; 57% females) with type 1 diabetes and 48 controls were enrolled. The median (IQR) HbA1c was 7.6% (60 mmol/mol) (6.9-8.1%, 52-65 mmol/mol), and the median (IQR) duration of disease was 6.0 (3.3-10.3) years. …”
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Adquisición de unidades verbales en niños/as que desarrollan el chedungun en la región del Biobío by Jonathan Miranda Espinoza, Pilar Vivar Vivar

“…Este proceso es in situ con participación directa de las familias y contempla el registro periódico de los niños/a durante un año. Dentro de los resultados, se evidencia una adquisición sistemática de verbos, en ambos niños/as mapuche. …”
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Exploring the influence of age on the causes of death in advanced nasopharyngeal carcinoma patients undergoing chemoradiotherapy using machine learning methods by Mengni Zhang, Shipeng Zhang, Xudong Ao, Lisha Liu, Shunlin Peng

“…A total of 2841 patients (1037 classified as older, ≥ 60 years and 1804 as younger, < 60 years) were enrolled. Variations in the CODs between the two age groups were analyzed before and after applying inverse probability of treatment weighting (IPTW). …”
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The Role of β-Catenin in Th1 Immune Response against Tuberculosis and Profiles of Expression in Patients with Pulmonary Tuberculosis by Kunlong Xiong, Jinxia Niu, Ruijuan Zheng, Zhonghua Liu, Yanzheng Song, Lin Wang, Changtai Zhu, Lin Fan

“…Patients with PTB were enrolled, with blood samples collected and PBMCs isolated. …”
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Reagentes e resíduos químicos em laboratório de química (Programa de Iniciação Científica Voluntária) by Antonio Marcos de Oliveira Siqueira, Rafaela Moreira da Silva Cordeiro, Gustavo Carvalho Menezes

“…Dentro desta ótica, foi realizado o levantamento dos reagentes e demais agentes químicos, armazenados nos espaços físicos de dois laboratórios, onde são realizados experimentos envolvendo práticas relacionadas as disciplinas de Laboratório de Química Geral e Laboratório de Engenharia Química. …”
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Perfil nacional de uso de mercurio en Costa Rica a la luz de la entrada en vigencia del Convenio de Minamata by Adriana Fernández-Villalobos, Jorge Herrera-Murillo, José Pablo Sibaja-Brenes

“…De acuerdo con el análisis realizado, la minería artesanal se considera el sector más riesgoso, ya que los grupos mineros se encuentran en constante contacto con el metal y lo manipulan inadecuadamente; los centros de salud, hospitales y clínicas odontológicas están limitados por la falta de legislación y, por ello, se identifican debilidades como la falta de capacitación del personal respecto a los riesgos del mercurio y el almacenamiento de sus residuos en sitios inadecuados. …”
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The challenges of evidence-based prehabilitation in a real-life context for patients preparing for colorectal surgery—a cohort study and multiple case analysis by A. D. Talen, N. L. U. van Meeteren, J. A. Barten, I. Pereboom, W. P. Krijnen, H. Jager-Wittenaar, B. C. Bongers, G. van der Sluis

“…Methods In this observational cohort study with multiple case analyses, all patients who underwent colorectal surgery from January 2023 to June 2023 were enrolled. Patients meeting the criteria for low aerobic capacity or malnutrition were advised to participate in a prehabilitation program. …”
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