Vaccination with a Replication-Dead Murine Gammaherpesvirus Lacking Viral Pathogenesis Genes Inhibits WT Virus Infection by Dipanwita Mitra, Darby G. Oldenburg, J. Craig Forrest, Laurie T. Krug

“…To further improve the RDV vaccine and more closely model KSHV vaccine design, we generated an RDV lacking the unique M1-M4 genes and the non-coding tRNA-miRNA-encoded RNAs (TMERs) 6, 7, and 8 that collectively promote latency of MHV68 in vivo. …”
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Neuromorphic Digital-Twin-Based Controller for Indoor Multi-UAV Systems Deployment by Reza Ahmadvand, Sarah Safura Sharif, Yaser Mike Banad

“…By integrating spike coding with nature-inspired control principles inspired by tilapia fish territorial behavior, our system achieves sophisticated formation control and obstacle avoidance in complex urban environments. …”
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Spontaneous mutation reveals influence of exopolysaccharide on Lactobacillus johnsonii surface characteristics. by Nikki Horn, Udo Wegmann, Enes Dertli, Francis Mulholland, Samuel R A Collins, Keith W Waldron, Roy J Bongaerts, Melinda J Mayer, Arjan Narbad

“…During growth of the bacterium a rare but consistent emergence of an altered phenotype was noted, generating smooth colonies in contrast to the wild type rough form. …”
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“You get the money after waiting for long and you get less than you anticipated”: Experiences of persons with disabilities in accessing the district special grant in Uganda by Patrick Ojok, Joseph Mukasa

“… In 2010, Uganda scrapped an ambitious tax incentive provision in the Persons with Disabilities Act, 2006 that had allowed employers to claim up to 15% tax reduction in annual income provided that they hired at least 10 persons with disabilities at any job level. …”
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Biochemical and phylogenetic characterization of the wastewater tolerant Chlamydomonas biconvexa Embrapa|LBA40 strain cultivated in palm oil mill effluent. by Patrícia Verdugo Pascoal, Dágon Manoel Ribeiro, Carolina Ribeiro Cereijo, Hugo Santana, Rodrigo Carvalho Nascimento, Andrei Stecca Steindorf, Lorena C G Calsing, Eduardo Fernandes Formighieri, Bruno S A F Brasil

“…Carbohydrates comprised the major fraction of algal biomass (31.96%), while the lipidic fraction reached up to 11.3% of dry mass. Reductions of 99% in ammonium and nitrite, as well as 98% reduction in phosphate present in POME were detected after 5 days of algal cultivation. …”
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Plastome and transcriptome analysis reveals a degenerated photosynthesis-related pathway in the mycoheterotrophic vanilloid orchid Cyrtosia lindleyana by Shiou Yih Lee, Peishan Zou, Zhihui Chen, Kenji Suetsugu, Wenbo Liao

“…Results The plastome, despite its reduction to 89,414 base pairs, maintained its quadripartite structure. …”
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Influence of Information Technology on the Performance of Financial Institutions in Ntungamo: A Case Study of Centenary Bank Ntungamo Branch. by Murungi, Doreen

“…The study applied primary data using questionnaires and secondary data collected from the respective institution’s financial statements and summaries at the Centenary Bank Ntungamo branch. Editing, coding, classifying, and tabulation are the processing steps that were used to process data for better and more efficient analysis. …”
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Mitigating host microRNA interference to enhance mRNA vaccine efficacy in public health interventions by Tielong Xu, Ziqi Lin, Yicheng Yu, Muhammad Irfan, Munir Ahmed, Maya Septriana, Twinky Zebrina Cysta Sumantri, Anindini Winda Amalia, Bin Zheng

“…Furthermore, the commentary suggests two actionable strategies for evading miR interference: (1) Synonymous codon optimization at seed-match regions, achieving binding energy reduction while preserving antigenicity through degeneracy of genetic coding; (2) Targeted co-delivery of miR inhibitors. …”
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MicroRNA-Based Delivery Systems for Chronic Neuropathic Pain Treatment in Dorsal Root Ganglion by Stefan Jackson, Maria Rosa Gigliobianco, Cristina Casadidio, Piera Di Martino, Roberta Censi

“…In addition to that, there has been ongoing research with clinical evidence relating to the role of small non-coding ribonucleic acids known as microRNAs in regulating gene expressions affecting pain signals. …”
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Characterization and genome analysis of lytic Vibrio phage VPK8 with potential in lysing Vibrio parahaemolyticus isolates from clinical and seafood sources by Valalak Jintasakul, Jiranan Pattano, Sutima Preeprem, Pimonsri Mittraparp-arthorn

“…Phage morphology was characterized by transmission electron microscopy (TEM), while genomic features were analyzed using next-generation sequencing. Lytic characteristics, including latent period and burst size, were determined through one-step growth curves, and bacterial growth reduction was evaluated over a 24-h. …”
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Transcriptome analysis reveals PTBP1 as a key regulator of circRNA biogenesis by Mohan Wang, Shanshan Zheng, Yan Zhang, Jingwen Zhang, Fuming Lai, Cong Zhou, Qiangwei Zhou, Xingwang Li, Guoliang Li

“…Abstract Background Circular RNAs (circRNAs) are a class of non-coding RNAs generated through back splicing. High expression of circRNAs is often associated with numerous abnormal cellular biological processes. …”
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Protease-activated receptor-2 (PAR2) mutation attenuates airway fibrosis in mice during the exacerbation of house dust mite‑induced allergic lung disease by multi‑walled carbon nan... by Logan J. Tisch, Ryan D. Bartone, Silvio Antoniak, James C. Bonner

“…Methods The PAR2-mutant mice used were previously generated by replacing a 1.8-kb region of the PAR2 coding sequence with a neomycin resistance gene, which did not entirely delete the gene. …”
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Designing the alignment model of petrochemical projects with the country's industrial strategies in the Ministry of Petroleum by Abdolrasoul Shojaeian, ghanbar abbaspour esfadan, Changiz Valmohammadi, Aboutorab Alirezaei

“…Data analysis and model design were done through coding. The findings of the research showed that the alignment of the refinery projects with the country's industrial strategies in the Ministry of Oil, the enablers of the alignment include the maturity of communication and managerial factors and the exercise of authority, strategic technology planning and organizational architecture aligned with technology, partnership factors, human resources (innovation, entrepreneurship, expertise, knowledge), and the distinctive competence factors that lead to the realization of optimization results and reduction of capital and current costs and synergy in both sides of petro-refining and industry. …”
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miR-23b-3p, miR-126-3p and GAS5 delivered by extracellular vesicles inhibit breast cancer xenografts in zebrafish by Iulia Andreea Pelisenco, Daniela Zizioli, Flora Guerra, Ilaria Grossi, Cecilia Bucci, Luca Mignani, Giulia Girolimetti, Riccardo Di Corato, Vito Giuseppe D’Agostino, Eleonora Marchina, Giuseppina De Petro, Alessandro Salvi

“…Here, by using breast cancer (BC) cells treated with the multi-kinase inhibitor sorafenib, we generated EVs enriched in specific non-coding RNAs (miR-23b-3p, miR-126-3p, and the long ncRNA GAS5) and investigated their potential impact on the aggressive properties of the BC in vitro and in vivo using zebrafish. …”
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Establishment of human periodontal ligament cell lines with ALPL mutations to mimic dental aspects of hypophosphatasia by Jana Schiffmaier, Jana Schiffmaier, Sofia Rehling, Sofia Rehling, Katharina Marnet, Katharina Marnet, Angela Borst, Drenka Trivanović, Drenka Trivanović, Drenka Trivanović, Denitsa Docheva, Franz Jakob, Stephanie Graser, Marietta Herrmann, Daniel Liedtke

“…TNAP activity was furthermore investigated during in vitro osteogenic differentiation and strong suppression during this process in nearly all newly established lines was observed.DiscussionWe report the generation of a new set of immortalized ALPLtg PDL-hTERT cells for investigation of TNAP cellular function in PDL cells, which can be used in subsequent studies for deciphering molecular processes in dental cells affected by reduction of TNAP function.…”
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Efficient Realization of BCD Multipliers Using FPGAs by Shuli Gao, Dhamin Al-Khalili, J. M. Pierre Langlois, Noureddine Chabini

“…The main highlight of the proposed architecture is the generation of the partial products and parallel binary operations based on 2-digit columns. 1 × 1-digit multipliers used for the partial product generation are implemented directly by 4-bit binary multipliers without any code conversion. …”
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Model-Driven Development of Android Audio-based Applications by Reza Vakili, Leila Samimi-Dehkordi, Marzieh Varposhti

“…The framework comprises domain-specific metamodels, a graphical editor, and a transformation engine, enabling the automatic generation of application code and supporting customization within Android Studio. …”
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Loss of MEF2C function by enhancer mutation leads to neuronal mitochondria dysfunction and motor deficits in mice by Ali Yousefian-Jazi, Suhyun Kim, Jiyeon Chu, Seung-Hye Choi, Phuong Thi Thanh Nguyen, Uiyeol Park, Min-gyeong Kim, Hongik Hwang, Kyungeun Lee, Yeyun Kim, Seung Jae Hyeon, Hyewhon Rhim, Hannah L. Ryu, Grewo Lim, Thor D. Stein, Kayeong Lim, Hoon Ryu, Junghee Lee

“…However, the mechanism behind genetic mutations in the non-coding region of genes that affect epigenetic modifications remains unclear. …”
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Exploring large language models for summarizing and interpreting an online brain tumor support forum by Christy Muasher-Kerwin, M Courtney Hughes, Michelle L Foster, Ibrahim Al Azher, Hamed Alhoori

“…Summaries produced by LLMs aligned closely with human-generated thematic analysis, with significant reductions in time and labor. …”
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Presenting a model of ecotourism and sustainable tourism development with an emphasis on foreign exchange and economic development of Qeshm Island by Naser Rajabi, Vahid Reza Mirabi, Khosro Moradi Shahdadi

“…Ecotourism is a sustainable alternative to degraded livelihoods around protected areas in developing countries, and its contribution to poverty reduction is evident in terms of employment and income generation. …”
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