Showing 61 - 80 results of 93 for search 'Generation Kill', query time: 0.06s Refine Results
  1. 61

    Influence of the polysaccharide capsule on virulence and fitness of Klebsiella pneumoniae by Lisa Zierke, Rodi Mourad, Thomas P. Kohler, Mathias Müsken, Sven Hammerschmidt

    Published 2025-02-01
    “…In whole blood killing assays, we demonstrate that the K. pneumoniae capsule is essential for survival in human blood, protecting K. pneumoniae against recognition and clearance by the human immune system, as well as complement-mediated opsonization and killing. …”
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  2. 62

    Fully integrated wearable control system for micro/nanorobot navigation by Zhanxiang Zhang, Lin Wang, Fengqi Jiang, Shimin Yu, Fengtong Ji, Tianhao Sun, He Zhang, Yanhe Zhu, Hao Chang, Tianlong Li, Jie Zhao

    Published 2025-01-01
    “…Such a novel, feasible control strategy was validated in the biological experiment in which cancer cells were targeted and killed by photothermal therapy using micro/nanorobots and integrated control platform. …”
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  3. 63

    Photo‐inactivation of bacteria in hospital effluent via thiolated iron‐doped nanoceria by Sara Khan, Sulaiman Faisal, Dilawar Farhan Shams, Maryam Zia, Akhtar Nadhman

    Published 2019-10-01
    “…In this study, thiolated iron‐doped nanoceria was synthesised and tested for killing of microbes from hospital effluent. These particles were designed to inhibit the efflux pumps of the bacteria found in hospital effluent with further ability to activate in visible light via iron doping thus generating tunable amount of reactive oxygen species (ROS). …”
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  4. 64

    PSYCHOPATHIC PERSONALITY DISORDER IN LARSSON’S “THE GIRL WITH THE DRAGON TATTOO” by Christy Tisnawijaya, Puji Astuti

    Published 2020-10-01
    “…He was sexually assaulted by his father and was forced to watch him killing women. These experiences are the seeds of crimes that Martin commits as an adult. …”
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  5. 65

    Rhyme or Reason: Three Patterns of Poetic Interference in the British Crime Novel by Camille Fort-Cantoni

    Published 2004-12-01
    “…This essay shows how poetical elements may be integrated to a prose genre, the crime fiction narrative, and the perturbations they may generate. Conan Doyle’s Musgrave Ritual centers on a pattern of verse. …”
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  6. 66

    “It’s not what I saw, it’s not what I thought”: by Lindsey Dodd

    Published 2022-07-01
    “…Rachel was a Jewish child, persecuted, abused, but saved; Anne-Marie was the daughter of a railway resistance fighter who was deported and killed; Grégoire was a child evacuee who survived a violent bombardment. …”
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  7. 67

    THE ROLE OF THE MULTINATIONAL JOINT TASK FORCE IN COUNTER INSURGENCY IN NORTH EASTERN NIGERIA: THE BOKO- HARAMINSURGENCY by ODO CHRISTOPHER UBA

    Published 2024-08-01
    “…The study revealed that the counter insurgency against Boko Haram to some extent is succeeding as many of the insurgents have been killed, some repented while others fled and some surrenders their arms and themselves to the Multinational Joint Task Force. …”
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  8. 68

    Differences in cNOS/iNOS Activity during Resistance to Trypanosoma cruzi Infection in 5-Lipoxygenase Knockout Mice by Carolina Panis, Vanessa Jacob Victorino, Vera Lúcia Hideko Tatakihara, Rubens Cecchini, Luiz Vicente Rizzo, Lucy Megumi Yamauchi, Sueli Fumie Yamada-Ogatta, Marli Cardoso Martins-Pinge, Phileno Pinge-Filho

    Published 2019-01-01
    “…Nitric oxide (NO) is a key mediator of parasite killing in T. cruzi-infected mice, and previous studies have suggested that leukotrienes (LTs) essentially regulate the NO activity in the heart. …”
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  9. 69

    Adoptive cell transfer of piezo-activated macrophage rescues immunosuppressed rodents from life-threating bacterial infections by Xiaoyi Liu, Wenxiu Xu, Junkun Feng, Ying Wang, Kai Li, Yi Chen, Wenjun Wang, Weiwei Zhao, Shaohua Ge, Jianhua Li

    Published 2025-02-01
    “…Catalytic antibacterial nanoparticles that generate reactive oxygen species (ROS) are emerging, as a promising therapeutic approach in treating bacterial infection by boosting the innate immune defenses. …”
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  10. 70

    « Ce n’est pas ce que j’ai vu, ce n’est pas ce que j’ai pensé»  by Lindsey Dodd

    Published 2022-07-01
    “…Rachel was a Jewish child, persecuted, abused, but saved; Anne-Marie was the daughter of a railway resistance fighter who was deported and killed; Grégoire was a child evacuee who survived a violent bombardment. …”
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    Article
  11. 71

    Allogeneic CD33-directed CAR-NKT cells for the treatment of bone marrow-resident myeloid malignancies by Yan-Ruide Li, Ying Fang, Siyue Niu, Yichen Zhu, Yuning Chen, Zibai Lyu, Enbo Zhu, Yanxin Tian, Jie Huang, Valerie Rezek, Scott Kitchen, Tzung Hsiai, Jin J. Zhou, Pin Wang, Wanxing Chai-Ho, Sunmin Park, Christopher S. Seet, Caspian Oliai, Lili Yang

    Published 2025-02-01
    “…Using stem cell gene engineering and a clinically guided culture method, we generate allogeneic CD33-directed CAR-NKT cells with high yield, purity, and robustness. …”
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  12. 72

    Physiochemical and functional evaluation of the first-in-class anti-cancer IgE antibody drug, MOv18, through process development and good manufacturing practice production by Heather J Bax, Jitesh Chauhan, Alexandra J McCraw, Melanie Grandits, Chara Stavraka, Heike Lentfer, Tim Hillyer, Simon Carroll, Kim Vigor, Chris Selkirk, Mariangela Figini, Jack Cheeseman, Paulina A Urbanowicz, Richard A Gardner, Daniel I R Spencer, Nigel Westwood, Sarah Mellor, James Spicer, Debra H Josephs, Sophia N Karagiannis

    Published 2025-12-01
    “…Research-grade recombinant IgE antibodies have been generated and studied for several decades. The recent Phase 1 clinical trial of the first-in-class MOv18 IgE, however, necessitated the inaugural process development and scaled manufacture of a recombinant IgE to clinical quality standards. …”
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  13. 73

    Tides of Time: The Dutch Delta Works as Time-Mediating Climate Adaptation Infrastructure by Huub Dijstelbloem, Victor Toom, Annick de Vries

    Published 2025-02-01
    “…This article argues that climate adaptation infrastructures mediate between different temporal regimes and can even be said to generate temporal regimes themselves. By examining the development of the Dutch Delta Works, a set of infrastructures initiated after the 1953 North Sea floods that killed more than 1,800 people, the article reconceptualizes the development from the response to the 1953 disaster to its current relationship with the consequences of climate change, in particular rising sea levels, river water inflows and weather fluctuations such as increased rainfall. …”
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  14. 74

    Cell Therapy for Chemically Induced Ovarian Failure in Mice by Paula Terraciano, Tuane Garcez, Laura Ayres, Isabel Durli, Melchiani Baggio, Cristiana Palma Kuhl, Claudia Laurino, Eduardo Passos, Ana Helena Paz, Elizabeth Cirne-Lima

    Published 2014-01-01
    “…Studies modeling this in mice have shown that cells transplantation generates donor-derived oocytes in chemotherapy-treated recipients. …”
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  15. 75

    Drug-induced differential culturability in diverse strains of Mycobacterium tuberculosis by Valerie F. A. March, Nino Maghradze, Kakha Mchedlishvili, Teona Avaliani, Rusudan Aspindzelashvili, Zaza Avaliani, Maia Kipiani, Nestani Tukvadze, Levan Jugheli, Selim Bouaouina, Anna Doetsch, Galo A. Goig, Sebastien Gagneux, Sonia Borrell

    Published 2025-01-01
    “…In patients, serial sputa were more likely to generate Mtb-positive cultures in liquid as opposed to solid medium, with this liquid culture bias extending up to 5 months post diagnosis. …”
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  16. 76

    Peculiarities of archival information resources legal regulation in the field of research on the development of the rocket and space industry by L. M. Popova, А. V. Khromov

    Published 2023-07-01
    “…It has been noted that in the course of military events on the territory of Ukraine, where the Russian Federation has fired thousands of ballistic and cruise missiles, killing thousands of Ukrainians, interest in the topic of rocket and space technology has increased significantly. …”
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  17. 77

    Involvement of a 1-Cys peroxiredoxin in bacterial virulence. by Gilberto Hideo Kaihami, José Roberto Fogaça de Almeida, Suelen Silvana dos Santos, Luis Eduardo Soares Netto, Sandro Rogério de Almeida, Regina Lúcia Baldini

    Published 2014-10-01
    “…The killing of bacterial pathogens by macrophages occurs via the oxidative burst and bacteria have evolved to overcome this challenge and survive, using several virulence and defense strategies, including antioxidant mechanisms. …”
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  18. 78

    Wartime activities of the Vavilov Institute by I. G. Loskutov

    Published 2021-07-01
    “…In the harsh reality of the winter in 1941–1942, the daily bread rationing was cut down, and hunger raged in the city, killing tens of thousands of city residents, including VIR employees who kept the stored seeds and tubers untouched. …”
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  19. 79

    Metabolic consequences of erastin-induced ferroptosis in human ovarian cancer cells: an untargeted metabolomics study by Kaylie I. Kirkwood-Donelson, Alan K. Jarmusch, Carl D. Bortner, Bruce Alex Merrick, Birandra K. Sinha

    Published 2025-01-01
    “…Erastin (ER), a ferroptosis inducer, kills tumor cells by generating and accumulating reactive oxygen species (ROS) within the cell, resulting in an iron-dependent oxidative damage-mediated ferroptotic cell death.MethodsWe have utilized human ovarian cancer cell lines, OVCAR-8 and its adriamycin-selected, multi-drug resistance protein (MDR1)-expressing NCI/ADR-RES, both equally sensitive to ER, to identify metabolic biomarkers of ferroptosis.ResultsOur studies showed that ER treatment rapidly depleted cellular glutathione and cysteine and enhanced formation of ophthalamate (OPH) in both cells. …”
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  20. 80

    Dysregulated Circulating Dendritic Cell Function in Ulcerative Colitis Is Partially Restored by Probiotic Strain Lactobacillus casei Shirota by Elizabeth R. Mann, Jialu You, Verena Horneffer-van der Sluis, David Bernardo, Hafid Omar Al-Hassi, Jon Landy, Simon T. Peake, Linda V. Thomas, Cheng T. Tee, Gui Han Lee, Ailsa L. Hart, Parveen Yaqoob, Stella C. Knight

    Published 2013-01-01
    “…Human blood DC from healthy controls (control-DC) and UC patients (UC-DC) were conditioned with heat-killed LcS and used to stimulate allogeneic T cells in a 5-day mixed leucocyte reaction. …”
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