An antagonistic role of clock genes and lima1 in kidney regeneration by Xian He, Ziming Wang, Linxi Cheng, Han Wang, Yuhua Sun

“…Abstract The circadian clock genes are known important for kidney development, maturation and physiological functions. …”
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Pulp stones and kidney stones-related gene: An investigation of single nucleotide polymorphisms in the gene encoding parathyroid hormone by Prescila Mota de Oliveira Kublitski, Bruna de Souza Romano, Vania Gomes Moraes, Manoel Damião Sousa-Neto, Lívia Azeredo Alves Antunes, Erika Calvano Küchler, Leonardo Santos Antunes, João Armando Brancher, Edgard Michel-Crosato, Marilisa Carneiro Leão Gabardo

“…Purpose: The aim of this study was to investigate the association between the presence of PS and kidney stones (KS) and single nucleotide polymorphisms (SNPs) in the parathyroid hormone (PTH) gene, which is related to KS. …”
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ADIPOQ rs2241766 Gene Polymorphism and Predisposition to Diabetic Kidney Disease by Qiuxia Han, Wenjia Geng, Dong Zhang, Guangyan Cai, Hanyu Zhu

“…This meta-analysis was performed to obtain a more comprehensive estimation of the role of the single nucleotide polymorphism (SNP) rs2241766 in the ADIPOQ gene in the occurrence of diabetic kidney disease (DKD). …”
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Differential Expression of -Associated Genes in Autosomal Dominant Polycystic Kidney Disease by Yeon Joo Yook, Yu Mi Woo, Moon Hee Yang, Je Yeong Ko, Bo Hye Kim, Eun Ji Lee, Eun Sun Chang, Min Joo Lee, Sunyoung Lee, Jong Hoon Park

“…Autosomal dominant polycystic kidney disease (ADPKD) is characterized by formation of multiple fluid-filled cysts that expand over time and destroy renal architecture. …”
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Modeling Pkd1 gene-targeted strategies for correction of polycystic kidney disease by Almira Kurbegovic, Rey Christian Pacis, Marie Trudel

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Pretransplant Immune- and Apoptosis-Related Gene Expression Is Associated with Kidney Allograft Function by Dorota Kamińska, Katarzyna Kościelska-Kasprzak, Paweł Chudoba, Oktawia Mazanowska, Mirosław Banasik, Marcelina Żabinska, Maria Boratyńska, Agnieszka Lepiesza, Agnieszka Gomółkiewicz, Piotr Dzięgiel, Marian Klinger

“…Lowered pretransplant Th1-derived cytokine and apoptosis-related gene expressions were a hallmark of subsequent worse kidney function but not of acute rejection rate. …”
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Identification of common and specific fibrosis-related genes in three common chronic kidney diseases by Zhangning Fu, Xiaodong Geng, Chao Liu, Wanjun Shen, Zheyi Dong, Guannan Sun, Guangyan Cai, Xiangmei Chen, Quan Hong

“…Therefore, we conducted this study aiming at exploring the common and specific fibrosis-related genes involved in different types of CKD.Methods Kidney biopsy specimens from patients with different types of CKD and normal control subjects were analyzed using the NanoString nCounter® Human Fibrosis V2 Panel. …”
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Genetic association analysis of lipid-lowering drug target genes in chronic kidney disease by Yi Zhang, Yi Zhang, Guangyang Ou, Lei Peng, Jian Pan, Shaohua Zhang, Jianguo Shi

“…ObjectiveThe impact of lipid-lowering medications on chronic kidney disease (CKD) remains a subject of debate. …”
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Water homeostasis gene expression in the kidney of broilers divergently selected for water conversion ratio by Kentu Lassiter, Loujain Aloui, Elizabeth S. Greene, Marciela Maqaeda, Travis Tabler, Sami Dridi, Robert F. Wideman, Jr., Sara Orlowski, Walter G. Bottje

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THE DOWNREGULATION OF GENES CONTROLLING VASCULAR TONE IN KIDNEYS OF ISIAH RATS WITH STRESS-INDUCED ARTERIAL HYPERTENSION by O. E. Redina, L. O. Klimov, N. I. Ershov, T. O. Abramova, L. N. Ivanova, L. A. Markel

“…The transcriptional activity of genes was studied in kidneys of hypertensive ISIAH and normotensive WAG rats in order to detect genes significantly expressed in kidneys of just one of the analyzed strains. …”
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Genetic association study of TERT gene variants with chronic kidney disease susceptibility in the Chinese population by Yan Su, Yuan Feng, Xinran Lin, Chunyang Ma, Jiali Wei

Subjects: “…Chronic kidney disease…”
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Global Gene Expression Profiling in PPAR-γ Agonist-Treated Kidneys in an Orthologous Rat Model of Human Autosomal Recessive Polycystic Kidney Disease by Daisuke Yoshihara, Masanori Kugita, Tamio Yamaguchi, Harold M. Aukema, Hiroki Kurahashi, Miwa Morita, Yoshiyuki Hiki, James P. Calvet, Darren P. Wallace, Takafumi Toyohara, Takaaki Abe, Shizuko Nagao

“…Immunohistochemical analysis revealed that the gene product of this enzyme was highly expressed in PCK kidneys and decreased by PIO. …”
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Identification of Anoikis-Related Genes in Chronic Kidney Disease Based on Bioinformatics Analysis Combined with Experimental Validation by Liu H, Mei M, Zhong H, Lin S, Luo J, Huang S, Zhou J

“…Among the 4 types of CKD mouse models, the mRNA expression levels of LAMB3 and CDH3 were significantly (P< 0.05) up-regulated in the model group.Conclusion: We identified 6 hub genes that may serve as potential key biomarkers of Anoikis-related progression in CKD.Keywords: chronic kidney disease, bioinformatics analysis, anoikis, biomarkers…”
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The Potential Diagnostic Value of Immune-Related Genes in Interstitial Fibrosis and Tubular Atrophy after Kidney Transplantation by Bin Yang, Dike Shi, Yahong Chen, Yi Zhu

“…Raw data of IF/TA samples after kidney transplantation and control samples after kidney transplantation were extracted from the Gene Expression Omnibus (GEO) database (GSE76882 and GSE120495 datasets), and genes that were differentially expressed between the two groups (DEGs) were screened. …”
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A Novel Immune-Related Three-Gene Signature and Immune Infiltration Insights in Psoriasis and Chronic Kidney Disease by Yin T, Zhang T, Ma L

“…The aim of this study was to screen immunologically related biomarkers for psoriasis and chronic kidney disease with the objective of identifying specific molecular markers to improve the accuracy and sensitivity of disease diagnosis.Patients and Methods: To achieve this objective, common differentially expressed genes between psoriasis and chronic kidney disease were first identified. …”
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Novel Mutation in the PKHD1 Gene Diagnosed Prenatally in a Fetus with Autosomal Recessive Polycystic Kidney Disease by Pankaj Thakur, Paul Speer, Aleksandar Rajkovic

“…Amniocentesis was performed for karyotype and to search for mutations in the PKHD1 for the presumptive diagnosis of autosomal recessive polycystic kidney disease (ARPKD). In our patient, a maternally inherited, previously reported pathogenic missense mutation in the PKHD1 gene, c.10444C>T, was identified. …”
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Highly Effective Ex Vivo Gene Manipulation to Study Kidney Development Using Self-Complementary Adenoassociated Viruses by Tie-Lin Chen, Hong-Lian Wang, Yun-Hong Liu, Yin Fang, Rui-Zhi Tan, Pu-Hui Zhou, Qin Zhou, Xiao-Yan Lv

“…Repressing WT1 in cultured kidney using shRNA impairs tubule formation. We for the first time employed and validated scAAV as a gene delivery tool in cultured kidney. …”
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Effect of vasopressin on the expression of genes for key enzymes of interstitial hyaluronan turnover and concentration ability in WAG rat kidneys by L. N. Ivanova, A. V. Babina, G. S. Baturina, L. E. Katkova

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A risk signature constructed by Tregs-related genes predict the clinical outcomes and immune therapeutic response in kidney cancer by Gang Li, Jingmin Cui, Tao Li, Wenhan Li, Peilin Chen

“…Abstract Regulatory T cells (Tregs) have been found to be related to immune therapeutic resistance in kidney cancer. However, the potential Tregs-related genes still need to be explored. …”
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