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5121
Circular RNA RHOT1 Regulates miR-142-5p/CCND1 to Participate in Chondrocyte Autophagy and Proliferation in Osteoarthritis
Published 2022-01-01“…We observed that autophagy markers, including LC3 and beclin1, were repressed in clinical OA samples. …”
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5122
Investigation of <i>ITGB3</i> Heterogeneity to Overcome Trastuzumab Resistance in HER2-Positive Breast Cancer
Published 2024-12-01“…This study investigates the role of <i>ITGB3</i> heterogeneity in Trastuzumab resistance, focusing on its impact on TGF-β signalling and migration marker response. It also evaluates the potential of combining Trastuzumab with the integrin β3 inhibitor cilengitide to overcome resistance associated with <i>ITGB3</i> levels. …”
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5123
Boosting the Motor Outcome of the Untrained Hand by Action Observation: Mirror Visual Feedback, Video Therapy, or Both Combined—What Is More Effective?
Published 2018-01-01“…On the contrary, the combination of MVF and VT turns out to be less effective looking from clinical perspective. The gathered results suggest that action-related motor competence with the untrained hand is acquired by both mirror-based and video-based AO.…”
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5124
Anaplastic Thyroid Carcinoma: A ceRNA Analysis Pointed to a Crosstalk between SOX2, TP53, and microRNA Biogenesis
Published 2015-01-01“…In detail, silencing SOX2 in SW1736 is able to suppress the expression of the stem markers analysed, strongly sensitizing the line to treatment with chemotherapeutic agents. …”
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5125
Applications of Mesenchymal Stem Cells and Neural Crest Cells in Craniofacial Skeletal Research
Published 2016-01-01“…Previous studies have identified mouse- and human-specific MSC subsets using cell surface markers. Additionally, some studies have shown that a subset of MSCs is closely related to neural crest derivatives and endothelial cells. …”
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5126
LKM: A LDA-Based -Means Clustering Algorithm for Data Analysis of Intrusion Detection in Mobile Sensor Networks
Published 2015-10-01“…Intrusion detection system (IDS) is a kind of active network security technology to protect network from attacks. In the data gathering phase of IDS, due to the high-dimension data collected in multidimension space, great pressure has been put on the subsequent data analysis and response phase. …”
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5127
Five New Indole Alkaloid Derivatives from Deep-Sea Fungus <i>Aspergillus fumigatus</i> AF1
Published 2024-12-01“…Compounds <b>8</b> and <b>13</b> displayed significant downregulation of the mRNA expression levels of all three molecular markers (COL1A1, α-SMA and FN1), with compound <b>13</b> exhibiting the best performance among all the tested compounds.…”
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5128
İBN RÜŞD’ÜN TE’VİL ANLAYIŞI VE AKTÜEL DEĞERİ ÜZERİNE
Published 2009-11-01“…However, this constrictive attitude and his advices has not been accepted by muslim scholars in general and thelogians, exegetes and lawyers in particular. Moreover, today the meaning and content of the ‘philosopher’ has changed a little bit more and has narrowed.…”
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5129
Th2 Regulation of Viral Myocarditis in Mice: Different Roles for TLR3 versus TRIF in Progression to Chronic Disease
Published 2012-01-01“…Interestingly, TLR3-deficient mice developed an interleukin (IL)-4-dominant T helper (Th)2 response during acute CVB3 myocarditis with elevated markers of alternative activation, while TRIF-deficient mice elevated the Th2-associated cytokine IL-33. …”
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5130
Shikonin Induces Glioma Necroptosis, Stemness Decline, and Impedes (Immuno)Proteasome Activity
Published 2024-01-01“…This study elucidates Shikonin’s capacity to effectively induce necroptosis in glioma cells, concurrently mitigating glioma stemness, as evidenced by diminished levels of stem cell markers, namely SOX2, CD44, CHI3L1, and CD24. Our findings indicate that Shikonin-induced programed necrosis leads to a downregulation of proteasome activity and a decrease in the expression of immune proteasome subunits PSMB8/9/10 and PSME1/2/3, contributing to the attenuation of stemness in gliomas. …”
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5131
Successful Treatment of Fungal Dermatitis in a Bottlenose Dolphin (<i>Tursiops truncatus</i>)
Published 2025-01-01“…Hematological examination revealed a reduction in inflammatory markers after antifungal treatment and surgical resection of necrotic tissue on the edge of the tail fin. …”
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5132
Nitric Oxide Mediates Inflammation in Type II Diabetes Mellitus through the PPARγ/eNOS Signaling Pathway
Published 2020-01-01“…The results showed that excess NO increased the inflammation marker levels in T2DM, which is activated by the PPARγ/eNOS pathway. …”
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5133
Host-Guest Interaction between Herbicide Oxadiargyl and Hydroxypropyl- β -Cyclodextrin
Published 2013-01-01“…UV-Vis and NMR experiments allowed concluding that the stoichiometry of the OXA/HP-β-CD complex formed is 1 : 1. The gathered results can be regarded as an important step for its removal from industrial effluents and/or to increase the stabilizing action, encapsulation, and adsorption in water treatment plants.…”
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5134
Autoimmune encephalitis: case reports of anti-NMDAR and anti-CASPR2 encephalitides and literature review
Published 2021-12-01“…In clinical practice, neuronal antibodies remain the most significant diagnostic marker currently available. Prognosis of AE varies greatly depending on the subtype and the time of immunotherapy initiation. …”
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5135
The influence of vaginal microbiota on the pregnancy outcome of artificial insemination with husband's sperm based on microscope images combined with PCR fluorescence method
Published 2025-02-01“…Among women with successful pregnancy, the proportion of beneficial bacteria (such as lactic acid bacteria) is higher, while the abundance of pathogenic bacteria is significantly reduced. Specific microbial markers detected by PCR fluorescence method are positively correlated with pregnancy rate. …”
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5136
Association between HMGB1 and COPD: A Systematic Review
Published 2015-01-01“…To this purpose we reviewed experimental studies that investigated this alarmin as marker as well as a potential treatment in chronic obstructive pulmonary disease. …”
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5137
Antidiabetic and Antioxidant Properties of Triticum aestivum in Streptozotocin-Induced Diabetic Rats
Published 2013-01-01“…Various parameters were studied and the treatment group with the extract showed a significant increase in the liver glycogen and a significant decrease in fasting blood glucose, glycosylated hemoglobin levels, and serum marker enzyme levels. The total cholesterol and serum triglycerides levels, low density lipoprotein, and very low density lipoprotein were also significantly reduced and the high density lipoprotein level was significantly increased upon treatment with the Triticum aestivum ethanol extract. …”
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5138
Foundations of Second Language Acquisition: Strategies and Motivation of Banjarese Young Learners in Learning English as a Foreign Language
Published 2019-12-01“…The researchers used a mixed-method approach, collecting data from 60 student participants across 3 State Islamic Junior High Schools and 3 State Junior High Schools in the region. The data were gathered through a survey questionnaire and semi-structured interviews. …”
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5139
Interventional Treatment of Abdominal Compartment Syndrome during Severe Acute Pancreatitis: Current Status and Historical Perspective
Published 2016-01-01“…Abdominal compartment syndrome (ACS) in patients with severe acute pancreatitis (SAP) is a marker of severe disease. It occurs as combination of inflammation of retroperitoneum, visceral edema, ascites, acute peripancreatic fluid collections, paralytic ileus, and aggressive fluid resuscitation. …”
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5140
Comparative In Vitro Immune Stimulation Analysis of Primary Human B Cells and B Cell Lines
Published 2016-01-01“…As for the read-out for such screening assay, it is proposed that the expression of activation and costimulatory surface markers reliably reflects B lymphocyte activation.…”
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