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4261
Identification of SETD4 as an Onco‐Immunological Biomarker Encompassing the Tumor Microenvironment, Prognoses, and Therapeutic Responses in Various Human Cancers
Published 2025-01-01“…Furthermore, we investigated its association with cancer‐related pathways, the immune microenvironment, immunotherapy markers, and drug resistance signatures of chemotherapy. …”
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4262
Antiganglioside Antibodies and Inflammatory Response in Cutaneous Melanoma
Published 2020-01-01“…Antiganglioside antibodies associated with inflammation markers could be used as diagnostic, monitoring, and treatment tools in patients with cutaneous melanoma.…”
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4263
The impact of sleep interventions combined with enhanced nutritional support on sleep quality, nutritional status, pain management, psychological well-being, and quality of life in...
Published 2025-01-01“…Sleep quality (PSQI: 7.81 vs. 10.43, d = 0.81) and nutritional markers (e.g., prealbumin: 230.19 mg/L vs. 188.01 mg/L, d = 1.21 ) improved markedly. …”
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4264
SHP2 promotes the epithelial-mesenchymal transition in triple negative breast cancer cells by regulating β-catenin
Published 2025-01-01“…Downregulation of SHP2 also decreased the expression of mesenchymal markers but induced upregulation of the epithelial marker E-cadherin. …”
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4265
Anti-arthritic potential of crude sulfated polysaccharide from marine macroalgae Sargassum ilicifolium (Turner) C. Agardh: Regulation of cytokine cascade
Published 2025-01-01“…The body weight, paw volume, and biochemical markers (alanine aminotransferase, aspartate aminotransferase, creatinine, urea, and C-reactive protein levels) were also measured for each group coupled with histopathological and immunohistochemistry studies. …”
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4266
Genetic diversity and breeding value of synthetic hexaploid wheat introduced into the VIR collection
Published 2019-10-01“…To assess the diversity of SHWs, we also used gliadin proteins as informative biochemical markers. It was revealed that 21 SHWs were homogeneous, and the rest, heterogeneous. …”
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4267
<i>In silico</i> mapping of coronary artery disease genes
Published 2020-01-01“…The analysis was based on the results of the genome-wide association studies (GWAS) available from the open databases MICAD (120,575 people, 85,112 markers) and UK Biobank (337,199 people, 10,894,597 markers). …”
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4268
Elevated Plasma Level of 8-Hydroxy-2′-deoxyguanosine Is Associated with Primary Open-Angle Glaucoma
Published 2020-01-01“…To determine the association between plasma 8-hydroxy-2′-deoxyguanosine (8-OHdG) levels, a marker for oxidative DNA damage, and patients with primary open-angle glaucoma (POAG) or its clinical phenotypes. …”
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4269
Study on the effects of Mogroside V in inhibiting NLRP3-mediated granulosa cell pyroptosis and insulin resistance to improve PCOS
Published 2025-01-01“…Expression of pyroptosis and insulin resistance markers was analyzed using qRT-PCR, Western blot, and IHC. …”
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4270
African animal trypanocide resistance: A systematic review and meta-analysis
Published 2024“…To address resistance, most preclinical studies increased the dosage and the treatment time, and this failed to improve the patient’s prognosis. Major markers of resistance explored include TbAT1, P1/P2 transporters, folate transporters, such as F-I, F-II, F-III, and polyamine biosynthesis inhibitors. …”
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4271
Training and Employee Performance in Uganda: A Case of National Water and Sewarage Corporation
Published 2024“…Self-administered questionnaires and interviews were used to gather primary data, and document reviews were used to gather secondary data. …”
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4272
Career Guidance and Academic Performance in Secondary Schools in Kisoro District; A case Study of Namirembe and Nyanamo Comprehensive Secondary Schools in Bukimbiri Sub-County.
Published 2020“…The literature that was reviewed for the study was gathered from different textbooks, manuals, reports, journals and from internet. …”
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4273
The Diagnostic Value of Plasma NETs Levels and iCEB in Silent Myocardial Ischemia in Maintenance Hemodialysis Patients
Published 2025-01-01“…Furthermore, electrocardiography findings, echocardiographic parameters, inflammatory markers, and cardiac biomarkers showed significant differences between the two groups. …”
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4274
Nitidine chloride inhibits the progression of hepatocellular carcinoma by suppressing IGF2BP3 and modulates metabolic pathways in an m6A-dependent manner
Published 2025-02-01“…Among potential botanical therapeutics, nitidine chloride (NC) has garnered attention for its potential anti-HCC properties. …”
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4275
NALCN expression is down-regulated and associated with immune infiltration in gastric cancer
Published 2025-02-01“…BackgroundNALCN has been identified as a tumor suppressor gene, and its role in human cancer progression has garnered significant attention. However, there is a paucity of experimental studies specifically addressing the relationship between NALCN and immune cell infiltration in gastric cancer (GC).MethodsThe expression levels of NALCN in tumor tissues, peripheral blood and gastric cancer cells lines from patients with GC were assessed using RNA sequencing, immunohistochemistry (IHC) staining and RT-qPCR. …”
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4276
Unveiling sequence-agnostic mixed-chemical modification patterns for splice-switching oligonucleotides using the NATURA platform
Published 2025-03-01“…Chemical optimization of ribose has significantly advanced nucleic acid therapeutics (NATs) by improving the stability, specificity, and safety of therapies like small interfering RNAs, CRISPR-Cas9 guide RNAs, and GAPmers. Recent research has extended this approach to splice-switching oligonucleotides (SSOs), which target splicing events. …”
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4277
General method to synthesize aggregation‐induced emission molecules via carbon‐sulfur bond activation
Published 2025-01-01“…Abstract Poly‐substituted olefins, one of the most important aggregation‐induced emission luminogens (AIEgens), have garnered significant attention due to their various applications in chemical‐ and bio‐sensing, bio‐imaging, and opto‐electronics. …”
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4278
IL-6/GATA2/SERPINE1 pathway is implicated in regulating cellular senescence after acute kidney injury
Published 2025-02-01“…The role of cellular senescence in the progression of AKI has increasingly garnered attention in recent years. Our previous research has demonstrated that remote ischemic postconditioning (RIPC) can attenuate renal cellular senescence and elevation of serum level of interleukin-6 (IL-6) induced by ischemia-reperfusion injury following crush injury. …”
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4279
Eco-friendly synthesis of silver nanoparticles: Enhancing optimization reaction, characterization, and antimicrobial properties with Lantana camara from geothermal area
Published 2025-01-01“…Green synthesis methods for producing silver nanoparticles (AgNPs) have garnered significant attention for their potential in medical applications. …”
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4280
The Impact of Fermented Quinoa Sourdough with Enterococcus Strains on the Nutritional, Textural, and Sensorial Features of Gluten-Free Muffins
Published 2025-01-01“…As a result, there is a renewed interest in the fermentation of gluten-free cereals with lactic acid bacteria, which is associated with an improvement in the final baked goods. Quinoa is garnering growing attention due to its different nutrients and bioactive substances, and it is notably employed to build gluten-free goods. …”
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