Magnetic Resonance Imaging Evaluation in Patients with Linear Morphea Treated with Methotrexate and High-Dose Corticosteroid by Mohammad Shahidi-Dadras, Fahimeh Abdollahimajd, Razieh Jahangard, Ali Javinani, Amir Ashraf-Ganjouei, Parviz Toossi

“…The lack of correlative laboratory disease activity markers, control group, and clearly defined criteria to judge the MRI changes. …”
Get full text

Study of Zuojin Pill in Treating Chronic Atrophic Gastritis by UPLC-Q-TOF/MS Based on Serum and Urine Metabolomics Combined with Network Pharmacology by Shihua Wu, Xing Chen, Honghong Liu, Ruilin Wang, Jianyu Li, Jianxia Wen, Tao Yang, Ying Wei, Sichen Ren, Shizhang Wei, Manyi Jing, Haotian Li, Min Wang, Houlin Xia, Yanling Zhao

“…Validation of metabolic markers and key targets of network pharmacology through RT-PCR analysis showed that ZJP significantly downregulated a series of inflammatory markers, such as MAPK1, PKIA, RB1, SCN5A, RXRA, E2F1, PTGS1, IGF2, ADRB1, ADRA1B, PTGS2, and GABRA1. …”
Get full text

Inflammatory biomarkers profiles and cognition among older adults by Aline Thomas, Jing Guo, Dolly Reyes-Dumeyer, Danurys Sanchez, Nikolaos Scarmeas, Jennifer J. Manly, Adam M. Brickman, Rafael A. Lantigua, Richard Mayeux, Yian Gu

“…However, inflammatory markers are regulated and influenced by each other, and it is therefore important to consider a more comprehensive panel of markers to better capture diverse immune pathways and characterize the overall inflammatory profile of individuals. …”
Get full text

Laminin 521 Stabilizes the Pluripotency Expression Pattern of Human Embryonic Stem Cells Initially Derived on Feeder Cells by Halima Albalushi, Magdalena Kurek, Leif Karlsson, Luise Landreh, Kristín Rós Kjartansdóttir, Olle Söder, Outi Hovatta, Jan-Bernd Stukenborg

“…All cell lines expressed pluripotency markers at protein and RNA level and were able to differentiate into cell types of the three germ layers after being cultured on LN521 for nine passages. …”
Get full text

A Family History of Diabetes Modifies the Association between Elevated Urine Albumin Concentration and Hyperglycemia in Nondiabetic Mexican Adolescents by Aida Jiménez-Corona, Antonio Ávila-Hermosillo, Robert G. Nelson, Guadalupe Ramírez-López

“…We examined the frequency of elevated urine albumin concentration (UAC) and its association with metabolic syndrome (MetS) and metabolic markers in 515 nondiabetic Mexican adolescents stratified by family history of diabetes (FHD). …”
Get full text

Probing the Hepatic Progenitor Cell in Human Hepatocellular Carcinoma by Shu-Qin Jia, Jian-Jun Ren, Pei-De Dong, Xing-Kai Meng

“…Immunohistochemistry was performed on 107 paraffin-embedded hepatocellular carcinoma specimens with the marker of hepatocyte and hepatocellular carcinoma (HepPar1), biliary differentiation (CK7,CK19), haemopoietic stem cell (HSC) (c-kit/CD117, CD34, and Thy-1/CD90), HPC specific markers (OV-6), and Ki-67, p53 protein. …”
Get full text

Features of the course and treatment of low back pain in patients with reduced bone mineral density by N. M. Shuba, T. S. Tsymbaliuk, A. S. Krylova, T. D. Voronova

“…The dynamics of questionnaires and inflammatory markers during treatment was better in patients with normal BMD. …”
Get full text

Lycium ruthenicum Murr. treatment attenuates APPswE/PS1ΔE9 mouse model-like mitochondrial dysfunction in Slc25a46 knockout mouse model by Min Wang, Tianxiong Xu, Li Gao, Chujun Huang, Piao Xu, Congcong Gong, William Kwame Amakye, Linfeng Liao, Maojin Yao, Jiaoyan Ren

“…Moreover, whether similarities in mitochondrial morphology can be a suitable marker for screening and/or discovering mitochondrial-protective substances remains unknown. …”
Get full text

Routine antibiotics for infants less than 6 months of age with growth failure/faltering: a systematic review by Jai K Das, Zulfiqar Ahmed Bhutta, Abigail Smith, Aamer Imdad, Olivia Tsistinas, Emily Tanner-Smith, Melissa François, Fanny F Chen, Momal Sana

“…The comparison group was infants who received antibiotics according to the aforementioned guidelines.Primary and secondary outcomes The primary outcome was all-cause mortality, and secondary outcomes: clinical deterioration, antimicrobial resistance, recovery from comorbidity, adverse events, markers of intestinal inflammation, markers of systemic inflammation, hospital-acquired infections and non-response. …”
Get full text

Random Tree Algorithm to Analyse the Relation between Type of Traumatic Dental Injuries and Its Demographic and Predisposing Factors - A Cross-Sectional Study by Mohammad Kamran Khan, Mahendra Kumar Jindal

“…Materials and Methods: The present study's data were gathered by conducting the observational cross-sectional study among index age-groups 12 and 15 years children of randomly selected schools of different geographical regions. …”
Get full text

The Novel Methods for Analysis of Exosomes Released from Endothelial Cells and Endothelial Progenitor Cells by Jinju Wang, Runmin Guo, Yi Yang, Bradley Jacobs, Suhong Chen, Ifeanyi Iwuchukwu, Kenneth J. Gaines, Yanfang Chen, Richard Simman, Guiyuan Lv, Keng Wu, Ji C. Bihl

“…The sensitivities of the cell origin markers for ECs (CD105, CD144) and EPCs (CD34, KDR) were evaluated. …”
Get full text

Covid-19 and the South African Pentecostal Landscape: Historic Shift from Offline Liturgical Practice to Online Platforms by John Mhandu and Vivian Ojong

“…The prohibition of gatherings to promote social distancing culminated in the use of online platforms as an alternative to physical gatherings. …”
Get full text

Changes in Testing and Treatment Methods in Osteoporosis Care by Takashi Nagai, Koji Ishikawa, Koki Tsuchiya, Soji Tani, Yusuke Dodo, Yusuke Oshita, Keizo Sakamoto, Nobuyuki Kawate, Yoshifumi Kudo

“…In addition, more physicians chose to utilise bone metabolic markers due to their ease of measurement through blood tests and reduced diurnal variation. …”
Get full text

THE IMPACT OF HUMAN RESOURCE OUTSOURCING ON EMPLOYEE PERFORMANCE (A CASE STUDY OF ACCESS BANKPLC) by JOY DAMIAN-ONYIA

“…While observation and oral interviews were equally used to gather more insights into the research premise. Thus, the Bank's employees weresampled using simple random sampling and 84 respondents were used for this study. …”
Get full text

Epigenetic regulation of the nuclear genome associated with mitochondrial dysfunction in Leber’s hereditary optic neuropathy (LHON) by Aswathy P. Nair, Ambika Selvakumar, Janani Gopalarethinam, B. Abishek Kumar, Balachandar Vellingiri, Mohana Devi Subramaniam

“…Therefore, here, we studied the epigenetic alterations of NDUFS4 by focusing on histone activation and repressive markers. We isolated peripheral blood mononuclear cells (PBMCs) from LHON patients and healthy individuals and examined epigenetic modifications in ND4 mutant cells and control cells. …”
Get full text

Impact of Obesity-Associated SARS-CoV-2 Mutations on COVID-19 Severity and Clinical Outcomes by Ana B. Martínez-Martinez, Alexander Tristancho-Baró, Beatriz Garcia-Rodriguez, Marina Clavel-Millan, Maria Pilar Palacian, Ana Milagro, Antonio Rezusta, Jose M. Arbones-Mainar

“…C313T showed a 428% increase in mortality risk, marking it as a possible poor-prognosis marker. Interestingly, all three mutations were synonymous, suggesting adaptive roles in obesity-driven environments despite not altering viral protein structures. …”
Get full text

Microalbuminuria and Cardiovascular Risk Factors in Diabetic Patients from a Medical Office by Agustín Paramio Rodríguez, Gabriel Ignacio Hinojoza Alarcón

“…<strong>Background:</strong> the concept of microalbuminuria was introduced as an early marker of diabetic nephropathy and mortality. Microalbuminuria has become a prognostic marker of cardiovascular risk in both diabetics and non-diabetics. …”
Get full text

Prediction models for cognitive impairment in middle-aged patients with cerebral small vessel disease by Wei Zheng, Xiaoyan Qin, Ronghua Mu, Peng Yang, Bingqin Huang, Bingqin Huang, Zhixuan Song, Xiqi Zhu, Xiqi Zhu

“…The combination model of imaging markers and hippocampal texture did not yield improved a better diagnosis compared to the individual model (p &gt; 0.05).ConclusionThe hippocampal texture model is a surrogate imaging marker for predicting cognitive impairment in middle-aged CSVD patients.…”
Get full text

Adult Human Multipotent Neural Cells Could Be Distinguished from Other Cell Types by Proangiogenic Paracrine Effects via MCP-1 and GRO by Sung Soo Kim, Hee-Jang Pyeon, Yoon Kyung Bae, Hyun Nam, Chung Kwon Kim, Sun-Ho Lee, Kyeung Min Joo

“…Interestingly, the expression of cell type-specific markers of ahMNCs could not be differentiated from those of pericytes, mesenchymal stem cells (MSCs), or fNSCs. …”
Get full text

Cardiac Troponin T and Illness Severity in the Very-Low-Birth-Weight Infant by Danielle N. Lopes, José M. Moraes Ramos, Maria Elizabeth Lopes Moreira, Jofre A. Cabral, Manoel de Carvalho, José Maria de Andrade Lopes

“…Cardiac troponin T (cTnT) is the most useful marker of injury in adult population, but has not been extensively studied in this population. …”
Get full text