Showing 201 - 220 results of 2,583 for search 'GCHQ~', query time: 2.79s Refine Results
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    Therapeutic molecules for multiple human diseases identified from pigeon pea (Cajanus cajan L. Millsp.) through GCâMS and molecular docking by Deepu Mathew, Lidiya John P., Manila T.M., Divyasree P., Sandhya Rajan V.T.K.

    Published 2017-12-01
    “…Molecular mechanism behind the therapeutic potential of pigeon pea over the human diseases such as rheumatoid arthritis, breast cancer, type II diabetes, malaria, measles and sickle cell disease were revealed through docking of GCâMS identified phyto-compound ligands with candidate disease proteins. …”
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  5. 205

    Two-component system GrpP/GrpQ promotes pathogenicity of uropathogenic Escherichia coli CFT073 by upregulating type 1 fimbria by Xueping Li, Yu Pang, Lingyan Jiang, Le Liu, Jiarui Zhou, Chen Jin, Qian Wang, Hongmin Sun, Qing Li, Zhen Chen, Jingliang Qin, Jianwei Mu, Bin Liu, Qiyue Zhang, Yutao Liu, Lu Feng, Lei Wang

    Published 2025-01-01
    “…This study reported a previously uncharacterized two-component system (TCS) GrpP/GrpQ that directly activates type 1 fimbria expression to promote UPEC invasion and therefore pathogenicity in response to D-serine present in the host urine. grpP/grpQ mutation severely impaired UPEC invasion of BECs and decreased the bacterial burden and formation of intracellular bacterial communities in mouse bladders during acute UTI. grpP/grpQ is widely present in UPEC genomes but rarely in other E. coli genomes, suggesting that this TCS specifically contributes to UPEC evolution. …”
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    Prevalence of GCKR rs1260326 Variant in Subjects with Obesity Associated NAFLD and T2DM: A Case-Control Study in South Punjab, Pakistan by Tayyaba Nisar, Kashan Arshad, Zahid Abbas, Maira Ali Khan, Sohail Safdar, Rehan Sadiq Shaikh, Ali Saeed

    Published 2023-01-01
    “…The glucokinase regulatory protein (GCKR) regulates glycogen metabolism and insulin secretion, and the GCKR rs1260326 is a putative single nucleotide polymorphism (SNP) associated with metabolic disorders including nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes mellitus (T2DM). …”
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    IL-8, IL-10, TGF-β, and GCSF Levels Were Increased in Severe Persistent Allergic Asthma Patients with the Anti-IgE Treatment by Arzu D. Yalcin, Atil Bisgin, Reginald M. Gorczynski

    Published 2012-01-01
    “…We observed that SPA patients presented increasing levels of IL-8, IL-10, TGF-β and GCSF during the anti-IgE treatment in period of sampling times at 4 months and 18 months. …”
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  16. 216

    Quality education for all in an ideas-informed society: exploring idea-engagement amongst friendship networks and how education can prevent idea “echo-chambers” by Chris Brown, Jana Gross Ophoff, Graham Handscomb

    Published 2024-12-01
    “…Originality/value – The authors consider whether ideas-related discussion within politically homophilous networks is problematic for the IIS and what is required from education systems if we are to build individuals’ capacity to engage with ideas while escaping echo chambers.…”
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    Echo- and B-Type Natriuretic Peptide-Guided Follow-Up versus Symptom-Guided Follow-Up: Comparison of the Outcome in Ambulatory Heart Failure Patients by Gani Bajraktari, Nicola Riccardo Pugliese, Andreina D’Agostino, Gian Marco Rosa, Pranvera Ibrahimi, Luan Perçuku, Mario Miccoli, Gian Giacomo Galeotti, Iacopo Fabiani, Roberto Pedrinelli, Michael Henein, Frank L. Dini

    Published 2018-01-01
    “…Our aim was to determine whether a therapy guided by echo markers of left ventricular filling pressure (LVFP), lung ultrasound (LUS) assessment of B-lines, and BNP improves outcomes of HF patients. …”
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    COMPARISON MEASUREMENT AND CALCULATION OF BRAIN TUMOR IN MRI MODALITIES UTILISING SPIN-ECHO PULSE SEQUENCE T1-WEIGHTED CONTRAST AND DIGITAL IMAGE PROCESSING APPLICATIONS by Maizza Nadia Putri, Kusworo Adi, M.Irwan Katili, Sidin Hariyanto, Dwi Rochmayanti

    Published 2022-11-01
    “…Conclusion: The active contour segmentation method applied to pulse sequence spin-echo T1-weighted contrast can be utilized as an alternative measurement and calculation of brain tumors with a sensitivity and specificity value of 87.5%. …”
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