Pooled prevalence and subgroup variations of Tetralogy of Fallot among children and adolescents with congenital heart defect in Sub-Saharan Africa: A systematic review and meta-ana... by Biniam Endale Geleta, Abay Mulu

“…The subgroup analysis based on geographic regions revealed statistically significant difference.<h4>Conclusions and future implications</h4>The prevalence of Tetralogy of Fallot observed was found considerably higher compared to global estimate and reports of developed countries. …”
Get full text

RETRACTED ARTICLE: Synthesis of silver nanoparticles using Plantago lanceolata extract and assessing their antibacterial and antioxidant activities by Muhammad Zahir Shah, Zheng-Hui Guan, Ala Ud Din, Amjad Ali, Ata Ur Rehman, Kashif Jan, Shah Faisal, Shah Saud, Muhammad Adnan, Fazli Wahid, Saud Alamri, Manzer H. Siddiqui, Shamsher Ali, Wajid Nasim, Hafiz Mohkum Hammad, Shah Fahad

“…Outstanding antioxidant, antibacterial activities have been shown by NPs and can be used in various biological techniques in future research.…”
Get full text

Immunoregulatory programs in anti‐N‐methyl‐D‐aspartate receptor encephalitis identified by single‐cell multi‐omics analysis by Xinhui Li, Yicong Xu, Weixing Zhang, Zihao Chen, Dongjie Peng, Wenxu Ren, Zhongjie Tang, Huilu Li, Jin Xu, Yaqing Shu

“…These findings provide deeper insights into the molecular mechanism driving the pathogenesis of anti‐NMDARE and offer promising targets for future therapeutic intervention. Key points Significant B cell clonal expansion, particularly in plasma cells, driven by antigen recognition. …”
Get full text

The economic burden of Lyme disease and the cost-effectiveness of Lyme disease interventions: A scoping review. by Stephen Mac, Sara R da Silva, Beate Sander

“…Economic literature from countries with historically high incidence rates or increasing rates of Lyme disease are limited, and can be useful for future justification of resource allocation.…”
Get full text

Urban Economic Structures as Multidimensional Networks: A Complex Systems Framework for Analyzing Economic Development Trajectories by Shade T. Shutters

“…This framework offers potential applications including the ability to quantify structural change over time in response to a shock or to assess the relative difficulty of future desirable trajectories. More broadly, this framework might be applied to the study of structural change in other complex adaptive systems from human institutions to ecosystems.…”
Get full text

Assessing caregiver stress and resource needs in pediatric cancer care by Shaimaa Mohamed Amin, Mahmoud Abdelwahab Khedr, Azza Medhat Aziz Mansy, Ahmed Hashem El-Monshed, Mohamed Gamal Noaman Malek, Ayman Mohamed El-Ashry

“…Implementing caregiver-centered support programs in pediatric oncology can enhance the well-being of both caregivers and patients. Future research should explore sustainable strategies to further reduce caregiver burden. …”
Get full text

The Effect of Cumin on the Formation of <i>β</i>-Carboline Heterocyclic Amines in Smoked Meat and Simulated Systems by Xiuxiu Liu, Wenyu Chen, Minghao Sun, Xufang Lv, Xing Shen, Zhongping Chai, Maomao Zeng

“…This study not only provides the food industry with a potential natural additive to improve food safety and quality, but also offers new directions for future research, namely by comparing natural plant extracts from different origins to explore their potential applications in food processing.…”
Get full text

SDG11-Based Sustainability Assessment of Urban Communities: A Case Study of Changsha by Qin Shuqian, Zhang Nan, Zhu Peijuan, Zhang Yong, Zhang Chen

“…Then, in addition to the zoning results of core, central urban, and suburban areas, a differentiated governance path is proposed. (4) The assessment indicator system has high validity and needs to be further enhanced with a larger number of empirical cases in the future. The research results enrich the theoretical system of community sustainability and technical means of assessment. …”
Get full text

Quantification of antimicrobial use on Irish dairy farms: A comparison of three recording methods by Hannah Martin, Edgar Garcia Manzanilla, Simon J. More, Robert Hyde, Conor McAloon

“…This is an important finding for the future monitoring of AMU at a national level.…”
Get full text

Beyond the current state of just-in-time adaptive interventions in mental health: a qualitative systematic review by Claire R. van Genugten, Claire R. van Genugten, Melissa S. Y. Thong, Melissa S. Y. Thong, Melissa S. Y. Thong, Wouter van Ballegooijen, Wouter van Ballegooijen, Wouter van Ballegooijen, Annet M. Kleiboer, Annet M. Kleiboer, Donna Spruijt-Metz, Arnout C. Smit, Mirjam A. G. Sprangers, Mirjam A. G. Sprangers, Yannik Terhorst, Yannik Terhorst, Heleen Riper, Heleen Riper, Heleen Riper

“…Regarding the current state of studies, initial findings on usability, feasibility, and effectiveness appear positive.ConclusionsJITAIs for mental health are still in their early stages of development, with opportunities for improvement in both development and testing. For future development, it is recommended that developers utilize complex analytical techniques that can handle real-or near-time data such as machine learning, passive monitoring, and conduct further research into empirical-based decision rules and points for optimization in terms of enhanced effectiveness and user-engagement.…”
Get full text

Virulence factor discovery identifies associations between the Fic gene family and Fap2+ fusobacteria in colorectal cancer microbiomes by Geicho Nakatsu, Duhyun Ko, Monia Michaud, Eric A. Franzosa, Xochitl C. Morgan, Curtis Huttenhower, Wendy S. Garrett

“…The Fic family proteins that we find are encoded by fusobacteria and expressed by Fusobacterium animalis merit future investigation to assess their roles in colorectal cancer development and progression.…”
Get full text

Pediatric Intensive Care Unit Admissions for COVID-19: Insights Using State-Level Data by Rohit S. Loomba, Enrique G. Villarreal, Juan S. Farias, Ronald A. Bronicki, Saul Flores

“…These factors should be included in future studies using patient-level data.…”
Get full text

The scholarly and practice profile of respiratory therapists in Canada: A cross-sectional survey by Marco Zaccagnini, André Bussières, Peter Nugus, Andrew West, Aliki Thomas

“…Creating supportive environments, providing access to resources, and encouraging professional development activities may advance the scholarly practice of RTs. Future national surveys could employ random sampling strategies to achieve a more representative sample of the profession.…”
Get full text

The A to E (ABCDE) Pit Crew Model: A Novel Approach to Team Based Care of Critical Patients in the Prehospital Setting by Ayanna Walker, Adam Oswald, Jessica Wanthal, Christine Van Dillen, Cherian Plamoottil, Parth Patel, Maria Tassone, Latha Ganti

“…Our data identified that a formal instruction of the pit crew approach to a critical care scenario improved comfort in patient care. Future studies are needed evaluate other methods of training and the effects of continued formal pit-crew training over time.…”
Get full text

Risk factors for fear of falling in stroke patients: a systematic review and meta-analysis by Li Ma, Qi Xie, Juhong Pei, Ling Gou, Yabin Zhang, Juanping Zhong, Yujie Su, Xinglei Wang, Xinman Dou

“…Sensitivity analysis (leave-one-out method) showed that the pooled estimate was stable.Conclusion This meta-analysis indicated that female population, impaired balance ability, lower mobility, history of falls and walking aid in patients with stroke might be at greater risk for FoF. Future studies are recommended to determine other risk factors specific to patients with stroke.…”
Get full text

The neighborhood walk: introducing first-year medical students to social determinants of health in underserved neighborhoods by Tien C. Nguyen, Lilly W. Tang, Emma Bryant, Awa S. Jobe, Amy J. Yu, Yui Sugiura, Thuy Bui

“…Research has shown that community exposure and engagement during undergraduate medical education increases the likelihood of students working in underserved areas in the future. Given the limited research on the feasibility and educational effects of SDoH experiences implemented at the early stages of medical education, this study presents a unique perspective on an interactive learning opportunity during the preclinical curriculum. …”
Get full text

Integrated metabolome and transcriptome analysis reveals key genes and pathways associated with egg yolk percentage in chicken by Wen Li, Yuxing Luo, Shoujia Zhu, Mengyuan Wang, Xuli Zhao, Zhonghua Ning

“…Such insights may advance future strategies to improve egg quality and productivity in poultry breeding programs.…”
Get full text

Comparison of air-liquid interface transwell and airway organoid models for human respiratory virus infection studies by Camilla T. Ekanger, Camilla T. Ekanger, Camilla T. Ekanger, Nilima Dinesh Kumar, Rosanne W. Koutstaal, Fan Zhou, Martin Beukema, Joanna Waldock, Simon P. Jochems, Noa Mulder, Cécile A. C. M. van Els, Cécile A. C. M. van Els, Othmar G. Engelhardt, Nathalie Mantel, Kevin P. Buno, Karl Albert Brokstad, Karl Albert Brokstad, Agnete S. T. Engelsen, Agnete S. T. Engelsen, Rebecca J. Cox, Rebecca J. Cox, Barbro N. Melgert, Barbro N. Melgert, Anke L. W. Huckriede, Puck B. van Kasteren

“…Our collaborative efforts to harmonize infection experiments and compare ALI transwell and airway organoid models described here aid in advancing our understanding and improving the standardization of these complex in vitro respiratory models for future studies.…”
Get full text

Protocol paper: randomized controlled trial of the smart online-to-offline model development for chronic diseases management through digital health in real world setting by Jae Eun Shin, Juho Choi, Heejung Lee, Suk-Won Lee, Juhwan Oh

“…It offers insights into the nuanced effects of the intervention, highlighting the potential for tailoring future interventions for maximum benefit. By assessing its real-world effectiveness, this study can inform healthcare policies, expand the application scope of O2O service models, and identify additional chronic diseases that can benefit from digital health services. …”
Get full text

A Novel Immune-Related lncRNA-Based Model for Survival Prediction in Clear Cell Renal Cell Carcinoma by Zedan Zhang, Yanlin Tang, Yanjun Liu, Hongkai Zhuang, Enyu Lin, Lu Xie, Xiaoqiang Feng, Kaiwen Tian, Jiayi Zeng, Jiumin Liu, Yuming Yu

“…The five immune-related lncRNAs could potentially be therapeutic targets for immunotherapy in ccRCC in the future.…”
Get full text