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Oyster shells water extract ameliorates propylthiouracil-induced goitre in rats via PI3K/AKT/Bcl-2 pathway
Published 2025-06-01Get full text
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Mutations in the signal peptide of effector gene Pi04314 contribute to the adaptive evolution of the Phytophthora infestans
Published 2025-03-01“…The effector is under purifying selection, supported by the comparative analyses between its population differentiation with that of SSR marker loci as well as by negative Tajima’s D (-1.578, p = 0.040) and Fu’s FS (-10.485, p = 0.000). Furthermore, we found that the nucleotide diversity of Pi04314 is significantly correlated with the annual mean temperature at the collection sites. …”
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Aloperine Protects Mice against DSS-Induced Colitis by PP2A-Mediated PI3K/Akt/mTOR Signaling Suppression
Published 2017-01-01Get full text
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Phloretin-nanospanlastics for targeting the Akt/PI3K signaling pathways in dimethylhydrazine-induced colon cancer in mice
Published 2025-06-01“…Reduced plasma cancer antigen 19–9 (CA19–9) levels as well as improved of colon malondialdehyde (MDA), reduced glutathione (GSH), superoxide dismutase (SOD), interleukine-2 (IL-2), tumor necrosis factor-alpha (TNF-α), tumor growth factor-beta1 (TGF-β1), carcinoembryonic antigen (CEA), and tumor protein (P53) levels. Also, Ph-NSLs and 5FU, either alone or together, decreased the expression of the Akt and PI3K genes in the colon. …”
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The role of HDAC2 inhibition in cardioprotection against doxorubicin-induced myocardial injury
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Propolis as an Adjuvant for Colon Cancer Chemotherapy: Exploring its Potential on Apoptosis, Cell Cycle, and PI3K Expression
Published 2024-12-01“…Additionally, inhibition of the cell cycle at the G0-G1 and S phases was observed when propolis was combined with either 5-FU or oxaliplatin. PI3K expression was inhibited by propolis in combination with 5-fu or oxaliplatin. …”
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MUSTN1 and FABP3 interact to regulate adipogenesis and lipid deposition
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Causal role of MiRNAs in chronic rhinosinusitis: mendelian randomization and validation study
Published 2025-04-01Get full text
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