Triple Active Antiretroviral Regimen Including Enfuvirtide Via the Biojector is Effective and Safe by Mona Loutfy, Colin Kovacs

“…For full HIV virological suppression, three fully active antiretroviral agents are required. New drug classes should be included to ensure that agents are fully active. …”
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Efficacy of Ivermectin, Liquid Paraffin, and Carbaryl against Mange of Farmed Rabbits in Central Kenya by Kennedy O. Ogolla, Joyce Chebet, Robert M. Waruiru, Peter K. Gathumbi, Paul O. Okumu, Gabriel O. Aboge

“…The current study evaluated the efficacy of three commonly used therapeutic agents in Kenya against mange. In a controlled laboratory trial, 20 adult rabbits were recruited for the study (16 of which were infested with mange, while 4 were mange-free). …”
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Mission Planner: An Open-Source Alternative to Commercial Flight Planning Software for Unmanned Aerial Systems by Jesse Chintanadilok, Sahaj Patel, Yilin Zhuang, Aditya Singh

“…Free and open-source (FOSS) options may be a very useful alternative to commercial-off-the-shelf (COTS) UASs. …”
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Synthesis and QSAR Study of Some HDL Cholesterol Increasing Quinazolinone Derivatives by M. B. Deshmukh, Savita Dhongade (Desai)

“…We describe here an easy and efficient method to obtain S-alkylated derivatives of thio-quinazolinone using different alkylating agents via a solvent-free microwave-assisted method. …”
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Towards an agency-oriented model of congregational vitality: by C.A.M. Hermans

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Seeding the Spatial Prisoner’s Dilemma with Ulam’s Spiral by Tim Johnson

“…The classic spatial prisoner’s dilemma (PD) reveals pathways to cooperation by presenting a model of agents interacting on a grid. This paper brings these tools together via a deterministic spatial PD model that distributes cooperators at the prime-numbered locations of Ulam’s spiral. …”
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Antioxidant Properties of 5-ASA: Potential Mechanism for Its Anti-Inflammatory Activity by T Yamada, C Volkmer, MB Grisham

“…The authors' laboratory and others have demonstrated that 5-aminosalicylic acid (5-ASA) possesses potent antioxidant activity, including free radical scavenging properties and the ability to decompose neutrophilic oxidants (eg, hypochlorous acid) and detoxify hemoprotein-associated oxidizing agents. 5-ASA has the additional property of being able to chelate iron and render it poorly redox active. …”
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Enhanced effects of slowly co-released TGF-β3 and BMP-2 from biomimetic calcium phosphate-coated silk fibroin scaffolds in the repair of osteochondral defects by Jiping Chen, Yanyi Wang, Tianyi Tang, Baochao Li, Banani Kundu, Subhas C. Kundu, Rui L. Reis, Xingnan Lin, Huang Li

“…Abstract Bioactive agents have demonstrated regenerative potential for cell-free bone tissue engineering. …”
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BRAF inhibitor monotherapy in BRAFV600E-mutated pediatric low-grade glioma: a single center’s experience by S. S. McThenia, S. S. McThenia, S. S. McThenia, K. M. Reddy, K. M. Reddy, E. Damaraju, E. Castellino, Z. He, R. Beer, F. Chien, F. Chien, F. Chien, R. C. Castellino, R. C. Castellino, R. C. Castellino, A. E. Goldman-Yassen, A. E. Goldman-Yassen, J. R. Fangusaro, J. R. Fangusaro, J. R. Fangusaro, T. MacDonald, T. MacDonald, T. MacDonald

“…The aim herein was to investigate the efficacy and tolerability of single agent BRAF inhibitor treatment in BRAFV600E altered pLGG.MethodsA single institution retrospective chart review analysis was performed on patients, 0 to 21 years of age, with newly diagnosed and/or progressive BRAFV600E mutated pLGGs (WHO Grade 1 or 2) at Children’s Healthcare of Atlanta treated off-study with BRAF inhibitor monotherapy between 2013-2023. 2-year progression free survival (PFS) and objective tumor response was evaluated. …”
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Poly-ADP ribose polymerase (PARP) inhibitor regimens for platinum-sensitive ovarian cancer in randomized, double-blind, phase III controlled trials: protocol for a systematic revie... by Xiaolian Peng, Jie Liu

“…They have been indicated to improve progression-free survival or overall survival in patients with patients with platinum-sensitive ovarian cancer. …”
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Preparation and In Vitro Evaluation of Alginate Microparticles Containing Amphotericin B for the Treatment of Candida Infections by Merlis P. Alvarez-Berrios, Lisa M. Aponte-Reyes, Lourdes Diaz-Figueroa, Juan Vivero-Escoto, Alexis Johnston, David Sanchez-Rodriguez

“…Amphotericin B (AmB) is one of the most effective antifungal agents commonly used to treat this infection. However, it induces severe side effects such as nephrotoxicity, cardiac alterations, nausea, fever, and liver damage. …”
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Dual Biologic or Small Molecule Therapy in Pediatric Inflammatory Bowel Disease: A Single Center Experience by Cheng Guo, Jin Zhou, Guoli Wang, Jie Wu

“…Purpose: Currently, there is no clinical data reported on the therapy of dual biological agents in pediatric-onset inflammatory bowel disease (PIBD) patients in China. …”
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Book spreaders in the towns of Samogitian principality in the XVIII century by Elmantas Meilus

“… The free spread of Enlightenment books from Western Europe in the 18th century in the Samogitian principality (the books were presumably spread following the decision of sovereign Michał Korybut Wiśniowiecki issued in 1672) worried the leaders of the Catholic Church who were responsible for education in the Republic of Both Nations. …”
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Small Extracellular Vesicles Secreted by iPSC-Derived MSCs Ameliorate Pulmonary Inflammation and Lung Injury Induced by Sepsis through Delivery of miR-125b-5p by Wei Peng, Yun Yang, Jiaquan Chen, Zeyao Xu, Yuanlei Lou, Qi Li, Ning Zhao, Kejian Qian, Fen Liu

“…Small extracellular vesicles, secreted by mesenchymal stem cells (MSCs), derived from human-induced pluripotent stem cells (iMSC-sEV), possess striking advantages when incorporated MSCs and iPSCs, which are considered extremely promising cell-free therapeutic agents. However, no studies have yet been conducted to systemically examine the effects and underlying mechanisms of iMSC-sEV application on attenuated lung injury under sepsis conditions. …”
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Induction of Oxidative Stress in Kidney by Emin Ozbek

“…We searched the literature using PubMed, MEDLINE, and Google scholar with “oxidative stress, reactive oxygen species, oxygen free radicals, kidney, renal injury, nephropathy, nephrotoxicity, and induction”. …”
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Exploring green synthesis of parietin-mediated silver nanoparticles using γ-ray induced Xanthoria parietina foliose extracts for antibacterial potential by Sikander Ali, Alisha Moazzam, Saima Shahzad Mirza, Majid Mahmood, Sibtain Ahmed, Muhammad Usman Ahmad, Gildardo Rivera, Akhtar Rasool Asif, Muhammad Arshad, Mirza Imran Shahzad, Kaynat William, Sundas Sharif

“…The current results exhibited that Xa-AgNPs are potent bactericidal agents and should be considered a promising candidate to combat bacterial infections.…”
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Effect of Induced Plant Expression on Ants and Extrafloral Nectaries Number in Cotton and Castor by Nalini Thiyagarajan, Revathi Mani

“…Artificial induction techniques can be utilized in pest management programs to attract and conserve plant guards, viz., biocontrol agents, including ants in the field. EFN is a cheap resource in quickly and effectively maintaining consistent population levels of biocontrol agents within the crops, even during pest-free times.  …”
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A Potential Concept In The Management of Tumors With Modulation of Prostaglandin, Nitric Oxide and Antioxidants by Noori S. Al-Waili

“…Prostaglandins (PGs), nitric oxide (NO), free radicals and chronic inflammation play a major role in tumorogenesis. …”
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Neuroinflammation and Cerebrovascular Disease in Old Age: A Translational Medicine Perspective by Mario Di Napoli, Imtiaz M. Shah

“…Neuroinflammation and oxidative stress are important pathogenic processes occurring during the acute phase of cerebral ischemia. Free radical generation is also implicated in the aging process, and the combination of these effects in elderly stroke patients could explain the higher risk of morbidity and mortality. …”
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Black mulberry (Morus nigra L.) prevents deleterious effects of excess glucose in obese C. elegans decreasing lipofuscin accumulation and ROS production by Sonia Núñez, Adrián Millán-Laleona, Javier Cano-Lou, Andrea Corella, Cristina Moliner, Guillermo Cásedas, Filippo Maggi, Víctor López, Carlota Gómez-Rincón

“…Black mulberries have been traditionally used as antidiabetic agents and are a source of nutrients and phenolic compounds, particularly anthocyanins. …”
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