CYTOKINES AND PROTEINS OF THE EXTRACELLULAR MATRIX IN THE BLOOD OF RATS OF DIFFERENT AGES AFTER FILLING THE DEFECT IN THE FEMORAL METAPHYSIS WITH ALLOGENEIC BONE IMPLANTS SATURATED... by Petro Vorontsov, Frida Leontieva, Vladyslav Tulyakov, Igor Husakov

“…Bone remodeling in rats with MSCs was characterized by lower activity. In 12-month-old rats in comparison with 3-month-old animals we noted more active inflammation, with a slowed activity in bone remodeling.…”
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Analysis of factors causing delays in seeking medical attention and its relationship with short-term prognosis in patient with acute ischemic stroke (急性缺血性脑卒中患者延迟就医原因与短期预后相关性分析)... by PENG Hong (彭红), CHEN Xiangyang (陈向阳), ZHANG Xiuliang (张修亮)

“…The type of symptom identification and NIHSS score at 14th day of hospital admission in the Non-Delay group was lower than that in the Delay group(P＜0. 05). Conclusion There is a relationship between delays in seeking medical attention and type of symptom identification, which may affect the short-term prognosis in patient with acute ischemic stroke. …”
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The success of reforestation after experimental strip-shelterwood felling in the pine stands of the Eastern Polissia of Ukraine by Anatolyi Zhezhkun

“…After felling without the use of promotion measures for natural regeneration, the density of natural pine regeneration is 1.8-7.2 times lower than with soil mineralization. After carrying out the second cut of strip-shelterwood felling with a cutting cycle of 4-5 years and measures to promote natural regeneration for 2-4 years, the density of advance growth and self-sowing of pine in the age group of 4-8 years was 4.2-15.4 thousand pcs. .ha-1 (regeneration success is good and satisfactory). …”
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Investigation of the effect of intravitreal bevacizumab treatment on left heart function using speckle tracking echocardiography by Mehmet Şahinbaş, İdris Buğra Çerik, Duygu Yalınbaş Yeter

“…Results: Global longitudinal strain (GLS) values at three months were lower in the patients who participated in the study and this was statistically significant (−18.77±2.17, −18.60±2.01, p=0.001). …”
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Investigation on health behavior of middle-aged and elderly patients with ischemic stroke and analysis of its influencing factors (中老年缺血性脑卒中患者健康行为现状调查及影响因素分析)... by LONG XinLing (龙鑫伶), YANG Mingchun (杨鸣春), ZOU Airong (邹爱容)

“…Conclusion The health behavior of middle-aged and elderly patients with ischemic stroke was at the lower level, which needs to be improved. Attention should be paid to the influence of patients' access to health information, sedentary time on screen and the number of chronic diseases on health behavior, focusing on patients with short sleep time. …”
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Production of Arthrospira platensis algae to increase production efficiency and enhance immune system of grass carp, Ctenopharyngodon idella against Aeromonas hydrophila by Hossein Adineh

“…Results: The growth of fish in the treatments containing spirulina was significantly higher and the feed conversion ratio was lower compared to the control treatment. Highest protease and lipase activities were observed in S2 and S3 treatments, respectively. …”
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Pengaruh Masase pada Punggung Terhadap Intensitas Nyeri Kala I Fase Laten Persalinan Normal Melalui Peningkatan Kadar Endorfin by Yeni Aryani, Masrul ., Lisma Evareny

“…The results of this study shows that mothers who have massage on the back before delivery process, feel lower pain intensity in 29.62 points than those who do not have massage. …”
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A prospective cohort study on the impact of healthy lifestyles on all-cause and cardiovascular disease mortality among adult residents in Guizhou province by Jie ZHOU, Ling LI, Ji ZHANG, Lisha YU, Yujin REN, Wei JI, Yingjiao MU, Tao LIU

“…ConclusionsThe more healthy lifestyle factors adopted by adult residents in Guizhou province, the lower their risks of all-cause and CVD mortality.…”
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Cerebral microvascular density, blood-brain barrier permeability, and support for neuroinflammation indicate early aging in a Marfan syndrome mouse model by Tala Curry-Koski, Tala Curry-Koski, Liam P. Curtin, Mitra Esfandiarei, Mitra Esfandiarei, Mitra Esfandiarei, Theresa Currier Thomas, Theresa Currier Thomas, Theresa Currier Thomas, Theresa Currier Thomas

“…We have reported that pre-mature vascular aging in MFS mice could extend to cerebrovasculature, where peak blood flow velocity in the posterior cerebral artery (PCA) of 6-month-old (6M) MFS mice was reduced, similarly to 12-month-old (12M) control mice. …”
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Dual Role of α-MSH in Colitis Progression: Mediating Neutrophil Differentiation via Bone Marrow by Liao X, Liu H, Li Y, Zhang W, Dai Q, Wei H, Zhou J, Xie X, Zhou H

“…Additionally, we used flow cytometry, adeno-associated virus-mediated gene silence, parabiosis and single-cell RNA sequencing to uncover the specific roles and mechanisms of the HPA in colitis.Results: Our results indicate that colitis activates HPA secretion and increases α-MSH. α-MSH acts on the MC5R present on the surface of hematopoietic stem cells (HSCs) in the bone marrow, altering the bone marrow microenvironment and promoting HSCs proliferation and differentiation into neutrophils. …”
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Screening and characterization of the scFv for chimeric antigen receptor T cells targeting CEA-positive carcinoma by Chengcheng Zhang, Linling Wang, Qianzhen Zhang, Junjie Shen, Xia Huang, Meiling Wang, Yi Huang, Jun Chen, Yanmin Xu, Wenxu Zhao, Yanan Qi, Yunyan Li, Yanjiao Ou, Zhi Yang, Cheng Qian

“…We monitored CAR-T cell phenotype and scFv binding stability to CEA antigen through flow cytometry. We performed repeated CEA antigen stimulation assays to compare the proliferation potential and response of the four CAR-T cells, then further evaluated the anti-tumor efficacy of CAR-T cells ex vivo and in vivo.ResultsM5A and hMN-14 CARs displayed higher affinity and more stable CEA binding ability than BW431/26 and C2-45 CARs. …”
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Exploring the Impact of Homophily Attitude, Physical, and Social Attractiveness on Purchase Intentions by Honya Ghasemi, Ramin Bashir Khodaparasti, Hooshmand Bagheri Garbollagh

“…ObjectiveAugmented reality technology has made its way into households, presenting a valuable opportunity for marketers to offer customers a seamless flow experience within the comfort of their homes. …”
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Post-COVID-19 laryngo-tracheal sequelae: a comprehensive study at a tertiary care centre by Karthik P., Rupa Mehta, Ranganath T. G., Ajoy K. Behra, Atul Jindal, Himanshi Grover

“…Moderate cases often necessitated oxygen supplementation through various means such as oxygen masks, non-rebreather masks, and high-flow nasal cannula, while severe cases required mechanical support and emergency procedures like intubation, continuous positive airway pressure, and tracheostomy. …”
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Beyond Chemistry: Investigating the Physical, Pharmacological, and Computational Aspects of Polyoxometalate Integrated Solid Lipid Nanoparticles for Cancer Treatment by Khan R, Tulain UR, Shah HS, Usman F, Chohan TA, Iqbal J, Kazi M, Ijaz M, Erum A, Malik NS, Mahmood A

“…Further examinations of DNA damage were made through comet test and flow cytometry techniques. The assessment of tumor regression and survival was conducted, and comparison was recorded. …”
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Mechanism of Spica Prunellae in Suppressing Proliferation and Stem Cell Properties of Colorectal Cancer Cells Based on Notch Signaling Pathway by TIAN Haoyuan, XIE Yi, FANG Yi, CHENG Ying, LIN Yan, SU Daifeng, WEI Lihui

“…The proliferation inhibition rate of colorectal cancer cells was detected using Cell Counting Kit-8 (CCK8) assay. Flow cytometry was used to detect the proportion of stem cells in colorectal cancer cells. …”
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Protective mechanism of safflower yellow injection on myocardial ischemia-reperfusion injury in rats by activating NLRP3 inflammasome by Lingmei Li, Ce Cao, Hao Guo, Li Lin, Lei Li, Yehao Zhang, Gaojie Xin, Zixin Liu, Shujuan Xu, Xiao Han, Qiong Zhang, Jianhua Fu

“…Methods The I/R model was prepared by ligating the left anterior descending coronary artery for 45 min and then releasing the blood flow for 150 min. 96 male Wistar rats were randomly divided into sham group, I/R group, Hebeishuang group (HBS), SYI high-dose group (I/R + SYI-H), SYI medium-dose group (I/R + SYI-M) and SYI low-dose group (I/R + SYI-L). …”
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The generation and evaluation of TKO/hCD55/hTM/hEPCR gene-modified pigs for clinical organ xenotransplantation by Guoli Huai, Yong Wang, Jiaxiang Du, Zhenhui Cheng, Yuxuan Xie, Jia Zhou, Hongmei Tang, Yanyan Jiang, Xiangyang Xing, Shaoping Deng, Dengke Pan, Dengke Pan, Dengke Pan

“…This study investigates the generation of TKO/hCD55/hTM/hEPCR (6GE) pigs and evaluates their compatibility with human immune and coagulation systems.MethodsThe 6GE pigs were generated through iterative genome editing and F1 generation breeding. Genotyping, flow cytometry, and immunohistochemistry confirmed the knockout of GGTA1, CMAH, and B4GALNT2. …”
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Awake prone positioning and ventilation distribution as assessed by electric impedance tomography in patients with non-COVID-19 acute hypoxemic respiratory failure: A prospective p... by Jingjing Wang, Changxing Chen, Zhanqi Zhao, Puyu Deng, Chenchen Zhang, Yu Zhang, Hui Lv, Daonan Chen, Hui Xie, Ruilan Wang

“…The study included patients with AHRF (partial pressure of oxygen [PaO2]/inspired oxygen concentration [FiO2] <200 mmHg or oxygen saturation [SpO2]/FiO2 <235) treated with high-flow nasal oxygen. Electrical impedance tomography (EIT) measurements including center of ventilation (COV), global inhomogeneity (GI) index, and regional ventilation delay (RVD) index were performed in the supine position (T0), 30 min after the start of APP (T1), and 30 min returning to supine position after the APP (T2). …”
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Inflammatory Monocyte Subsets Correlation with Iron Levels in Low Vitamin D Pediatric Transfusion-Dependent Thalassemia by Ghozali M, Matahari M, Cahyadi AI, Agustini SD, Ghrahani R, Reniarti L, Setiabudiawan B, Panigoro R

“…Considering the mechanisms of vitamin D activation and its potential interaction with monocytes, further investigation of its immunomodulatory role in transfusion-dependent thalassemia is essential.Purpose: This study evaluated monocyte subsets, population, and surface receptor expression (CD14, CD16, and HLA-DR), and their association with iron status and vitamin D levels in patients with transfusion-dependent thalassemia.Patients and Methods: Fifty lysed erythrocyte-heparinized whole blood samples from transfusion-dependent thalassemia patients were analyzed by flow cytometry and classified into three monocyte subsets: CD14++CD16- (classical), CD14++CD16+ (intermediate), and CD14+CD16++ (non-classical). …”
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Simultaneous Determination of Multiple Acid-Suppressing Drugs by UPLC-MS/MS Method and Application for Pharmacokinetics Study by Li X, Liu S, Yu M, Xi W, Wu X, Liu D, Liu A, Wang H

“…The mobile elution was composed of 0.2% formic acid in acetonitrile (mobile phase A), 0.1% ammonium hydroxide and 10 mmol/L ammonium formate in deionized water (mobile phase B). The flow rate was 0.4 mL/min, the run time was 4.5 minutes, and the injection volume was 20 μL.Results & Conclusions: The method exhibited excellent linearity across the ranges of 0.2– 200 ng/mL for PPIs and 0.5– 500 ng/mL for the P-CAB. …”
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