Application of family somatosensory game intervention in rehabilitation of COPD patients after discharge from hospital (家庭体感游戏干预在COPD患者出院后康复中的应用研究)... by FANG Huaqin (方华琴)

“…The score of Hospital Anxiety and Depression Scale(HADS) in the intervention group was lower than that of the control group after intervention(P＜0. 05). …”
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Treatment failure and drug resistance among the newly reported HIV-infected patients in Taizhou City from 2020 to 2022 by LI Yan, WU Xuanhe, SHI Lu, LI Guixia, WANG Shanling, WANG Yating, CHEN Tailin, WANG Tingting, XIE Yali, SHEN Weiwei, LIN Haijiang, CHEN Xiaoxiao, HE Na

“…Among the 66 patients with treatment failure (6.5%), the likelihood of treatment failure was lower in those with homosexual transmission (OR=0.39, 95%CI: 0.17‒0.84) and without history of sexually transmitted disease (STD) (OR=0.45, 95%CI: 0.24‒0.92), but higher in those with a baseline CD4 count of ≤200 cell·μL-1, delayed ART (OR=3.19, 95%CI: 1.24‒7.52), and primary drug resistance (OR=4.69, 95%CI: 1.68‒11.89). …”
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Mechanism of warmed malate ringer’s solution in fluid resuscitation in improving the lethal triad of severe trauma by WU Yinyu, SHE Han, SHE Han, DU Yunxia, DU Yunxia

“…Results‍　‍Compared with the Sham group, the severely traumatic rats at 180 min after injury had significantly prolonged ACT and R values (P<0.05), shortened MA and decreased Angle values (P<0.05), extended tail bleeding time (P<0.05), lower partial pressure of carbon dioxide (PCO2) and HCO 3 - and base excess (BE) levels (P<0.05), and continuously increasing K+ (P<0.05) and decreasing Na+ (P<0.05) and Ca2+ levels (P<0.05). …”
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Additive effect of brimonidine in maximum tolerated medical therapy for primary open-angle glaucoma by D.A. Dorofeev, V.P. Balukhtina, M.V. Es’kova, K.A. Efimova, E.V. Kirilik, K.O. Luk’yanova

“…&nbsp;Luk’yanova¹</b> </p> <p> <b>¹City Clinical Hospital No. 2, Polyclinic № 1, Chelyabinsk, Russian Federation</b> </p> <p> <b>²South Ural State Medical University, Chelyabinsk, Russian Federation</b> </p> <p> <i><b>Aim</b>: to evaluate additive IOP-lowering effect of brimonidine 0.2% to achieve target IOP via enhancing maximum tolerated medical therapy for primary open-angle glaucoma (POAG).…”
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Mitral Valve Repair by Irbaz Hameed, MD, Adham Ahmed, BS, Christina Waldron, BS, Percy T. Algarate, MD, Michal Kawczynski, MD, Maurish Fatima, MBBS, BS, Amnah Alhazmi, MBBS, Samantha Colon, BS, Alexandria Brackett, MA, MLIS, Samuel Heuts, MD, PhD, Peyman Sardari Nia, MD, PhD, Mario Gaudino, MD, PhD, Vinay Badhwar, MD, Arnar Geirsson, MD

“…The overall pooled 10-year survival was 70.8% (95% CI: 68.9%-72.8%). Compared to lower volume centers, centers performing >38 cases/y were associated with significantly improved long-term survival (HR: 0.42; 95% CI: 0.36-0.49; P < 0.001). …”
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JAUNOSIOS KARTOS KATALIKŲ INTELEKTUALŲ POŽIŪRIS Į FAŠIZMĄ IR NACIONALSOCIALIZMĄ TARPUKARIO LIETUVOJE by Valdas Pruskus

“…This salvation ought to be realized through a mass extermination of races of lower level, first of all, Jews. The theory of race inferiority preached by the Nazi and used by them as foundation of their activities, was antiscientific, and this was persuasively proved in the study of M. …”
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The digestibility of biofloc meal from African catfish culture medium as a feed raw material for Pacific white shrimp by Julie Ekasari, Muhammad Agus Suprayudi, Putri Elas, Reza Karunia Senja

“…Feeding shrimp with 30% biofloc meal diet resulted in higher survival and specific growth rate and lower feed conversion ratio than those of the control. …”
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Observation on the curative effect of umbilicus application therapy combined with Cucurbit moxibustion in the treatment of spleen deficiency syndrome of type 2 diabetes mellitus (敷... by GAO Junluan (高俊娈), XUE li (薛丽), ZHANG Gengliang (张庚良), HAO Min (郝民), MAO Hui (毛慧), SHEN Yanru (沈彦如)

“…After intervention, the total score of spleen deficiency symptom, FBG level and 2hPBG level in the treatment group were lower than those in the control group (P<0. 05). …”
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Effect of different hormonal protocols with timed AI on clinical signs of estrus and conception rates in Bulgarian Murrah buffaloes by Radena Nenova

“…At the same time, in the buffalo cows, the differences are lower, the Ovsynch pro- tocol having a relatively low pregnancy rate (38.3%), Ovsyn- ch+PRID – highest (45.0%), and Presynch/Ovsynch – lowest (30.4%). …”
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Ovarian cancer prevention through opportunistic salpingectomy during abdominal surgeries: A cost-effectiveness modeling study. by Angela Kather, Habib Arefian, Claus Schneider, Michael Hartmann, Ingo B Runnebaum

“…ICER of strategies I and II was lower than the 2× gross domestic product per capita (GDP/C) (€94,366/QALY, Germany 2022) within the range of all tested parameters, but strategy III exceeded this threshold in case-risk reduction was <35% (HR > 0.65). …”
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Does coenzyme Q10 improve semen quality and circulating testosterone level? a systematic review and meta-analysis of randomized controlled trials by Tunmise M. Akhigbe, Tunmise M. Akhigbe, Fabrael B. Fidelis, Fabrael B. Fidelis, Adebayo O. Adekunle, Adebayo O. Adekunle, Victory J. Ashonibare, Victory J. Ashonibare, Bolaji A. Akorede, Bolaji A. Akorede, Mansur S. Shuaibu, Mansur S. Shuaibu, Suliat A. Hassan, Cecilia A. Adegbola, Cecilia A. Adegbola, Precious J. Ashonibare, Precious J. Ashonibare, Opeyemi M. Oladapo, Opeyemi M. Oladapo, Adetomiwa E. Adeogun, Adetomiwa E. Adeogun, Adetomiwa E. Adeogun, Seun G. Bamidele, Seun G. Bamidele, Precious A. Oyedokun, Precious A. Oyedokun, Mungala Mukolokota, Mungala Mukolokota, Omotolani S. Kukoyi, Omotolani S. Kukoyi, Ayoola A. Oladipo, Ayoola A. Oladipo, Olayinka E. Adelowo, Olayinka E. Adelowo, Marvelous D. Akangbe, Marvelous D. Akangbe, Jennifer R. Hughes, Albert M. Ricken, Martine Culty, Maria C. W. Avellar, Roland E. Akhigbe, Roland E. Akhigbe

“…In addition, CoQ10 supplementation significantly lowered serum LH (SMD 1.77 [95% CI: 1.26, 2.28] P&lt; 0.00001) and FSH concentrations (SMD 1.60 [95% CI: 1.38, 1.81] P&lt; 0.00001). …”
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Exploring the minds of rural seniors: A journey into cognitive health in aging communities by Raju Naganandini

“…Rural areas often face unique challenges that can impact cognitive health, including limited access to health-care services, lower educational opportunities, and lifestyle factors that may differ significantly from urban counterparts. …”
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The growth performance and physiological status of comet goldfish Carassius auratus in aquascape with different aquatic plant species by Rafiatun Indriani, Yani Hadiroseyani, Iis Diatin, Media Fitri Isma Nugraha

“…After blood glucose test, comet goldfish that reared with aquatic plants consistently showed a lower blood glucose level than without aquatic plants. …”
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Long-Term Impact of Using Mobile Phones and Playing Computer Games on the Brain Structure and the Risk of Neurodegenerative Diseases: Large Population-Based Study by Yi Xiao, Sirui Zhang, Yuanzheng Ma, Shichan Wang, Chunyu Li, Yan Liang, Huifang Shang

“…However, higher weekly usage time did not confer additional risk reduction compared to lower weekly usage of mobile phones. The neuroimaging analysis involved 35,643 participants, with an average duration of approximately 9.0 years between baseline and neuroimaging scans. …”
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Improving the hydrological consistency of a process-based solute-transport model by simultaneous calibration of streamflow and stream concentrations by J. Salmon-Monviola, O. Fovet, M. Hrachowitz

“…Parameter uncertainty decreased when the model was calibrated using solute concentrations, except for parameters related to fast and slow reservoir flow. This study shows the added value of using multiple types of data along with streamflow, in particular DOC and NO<span class="inline-formula"><math xmlns="http://www.w3.org/1998/Math/MathML" id="M4" display="inline" overflow="scroll" dspmath="mathml"><mrow><msubsup><mi/><mn mathvariant="normal">3</mn><mo>-</mo></msubsup></mrow></math><span><svg:svg xmlns:svg="http://www.w3.org/2000/svg" width="9pt" height="16pt" class="svg-formula" dspmath="mathimg" md5hash="0723f17b5be9fc41c36a5585631feb47"><svg:image xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="hess-29-127-2025-ie00004.svg" width="9pt" height="16pt" src="hess-29-127-2025-ie00004.png"/></svg:svg></span></span> concentrations, to constrain hydrological models to improve representation of internal hydrological states and flows. …”
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Effect of Berberine on the Inflammatory Response of ANA-1 Cells Induced by Angiotensin Ⅱ Based on TLR4 Signaling Pathway by GAO Dexing, JIA Peizhi, PENG Jun, LIN Wei

“…Cell proliferation and toxicity test (CCK-8) was used to detect the effect of different concentrations of BBR on cell viability; the flow cytometry was used to detect the mean fluorescence intensity (MFI) of TLR4 on cell membrane ; ELISA method was used to detect the content of interleukin-1β (IL-1β), interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α); the real-time quantitative PCR was used to detect the mRNA level of IL-1β, IL-6, TNF-α; Western blot was used to detect the phosphorylation of p-ERK/ERK, p-p38/p38, p-JNK/JNK, p-p65/p65 and p-IRF3/IRF3 and the expression of TLR4, MyD88 and AP-1; the biochemical assay was used to detect the content of malondialdehyde (MDA) and the activity of superoxide dismutase (SOD).Results① CCK-8 assay results: compared with the control group, there was no significant difference in cell activity of the low, medium and high- dose BBR group, the difference was not statistically significant (<italic>P</italic>&gt;0.05). ② Flow cytometry results: compared with the fluorescent antibody group, MFI of the model group was significantly decreased; compared with the model group, MFI of the model group + the high dose BBR group was significantly increased, the difference was statistically significant (<italic>P</italic>&lt;0.05). ③ ELISA results: compared with the control group, the content of IL-1β, IL-6, TNF- α of the model group was significantly increased; compared with the model group, the content of IL-1β, IL-6, TNF- α of the model group + the low, medium and high dose BBR group was significantly decreased, the difference was statistically significant (<italic>P</italic>&lt;0.05). ④ Real-time quantitative PCR results: compared with the control group, the mRNA level of IL-1β, IL-6, TNF-α of the model group was significantly increased; compared with the model group, the mRNA level of IL-1β, IL-6, TNF- α of the model group + the low, medium and high-dose BBR group was significantly decreased, the difference was statistically significant (<italic>P</italic>&lt;0.05). ⑤ Western blot results: compared with the control group, the phosphorylation expression of p65 and IRF-3 protein of the model group after intervention for 45 minutes was significantly increased, and the phosphorylation expression of p65, IRF-3 protein in the model group + the low, medium and high-dose BBR group was significantly decreased. …”
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A pharmacoinformatic approach for studying Atractylodes Lancea DC’s anticancer potential and control ROS-mediated apoptosis against prostate cancer cells by Chi-Hoon Ahn, Ji Soo Myong, Kazi Rejvee Ahmed, Md Ataur Rahman, Md. Maharub Hossain Fahim, Min Choi, Muntajin Rahman, Jinwon Choi, Kiryang Kim, Seungjoon Moon, Seungjoon Moon, Mohammed Dalli, Mohammed Dalli, Rony Abdi Syahputra, Sang-Won Shin, Abdel Halim Harrath, Moon Nyeo Park, Bonglee Kim, Hwa-Seung Yoo

“…Apoptosis was further analyzed through an-nexin V-FITC/PI staining and quantified by flow cytometry (FACS). Western blotting was performed to elucidate the underlying molecular mechanisms. …”
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Pengaruh Perkembangan Sastra Arab Pada Era 5.0 by Adelia Finanti

“…The development of digital-based technology has disrupted the flow of social interactions in the real world, and social interactions now only occur digitally. …”
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The impact of CD3ζ ITAM multiplicity and sequence on CAR T-cell survival and function by Shubhabrata Majumdar, Hilda Echelibe, Maria Bettini, Matthew L. Bettini

“…We hypothesized that the individual CD3ζ ITAMs will exhibit unique signaling properties in the ITAM restricted CARs which may allow for optimization of CAR signaling and improve CAR T-cell persistence and function.MethodWe subjected the ITAM restricted CAR T cells to various conditions of in vitro stimulation using CD19+ tumor cells or CD19-coated magnetic beads. Immunoblotting and flow cytometry based Ca2+ signaling assays were used to quantify signaling differences. …”
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Club Cell Protein 16 Attenuates CD16brightCD62dim Immunosuppressive Neutrophils in Damaged Tissue upon Posttraumatic Sepsis-Induced Lung Injury by Nils Becker, Philipp Störmann, Andrea Janicova, Kernt Köhler, Klemens Horst, Ildiko Rita Dunay, Claudia Neunaber, Ingo Marzi, Jan Tilmann Vollrath, Borna Relja

“…PMNL were characterized via expression of CD11b, CD16, CD45, CD62L, and Ly6G by flow cytometry in bone marrow (BM), blood, spleen, lung, liver, and bronchoalveolar and peritoneal lavage fluid (BALF and PL). …”
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