The potential of Trichoderma sp. as antibacterial and immunostimulant on white shrimp (Litopenaeus vannamei) by Catur A. Pebrianto, . Sukenda, . Widanarni

“…., either prophylactic or therapeutic, showed protective effect against V. harveyi significantly higher than positive control and lower compared with negative control. Total haemocyte count (THC), differential haemocyte count (DHC), phagocytic index and phenoloxydase activity were different among the groups of prophylactic treatment or therapeutic treatment compared to control positive and negative treatments. …”
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UltraTimTrack: a Kalman-filter-based algorithm to track muscle fascicles in ultrasound image sequences by Tim J. van der Zee, Paolo Tecchio, Daniel Hahn, Brent J. Raiteri

“…It also yielded similar or lower root-mean-square deviations from manual tracking for previously published image sequences (fascicle length: 2.3–2.6 mm, fascicle angle: 0.8–0.9 deg) compared with a recently-proposed hybrid algorithm (4.7 mm, 0.9 deg), and the recently-proposed DL_Track algorithm (3.8 mm, 3.9 deg). …”
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Immunosuppressive therapy and nutritional diseases of patients after kidney transplantation: a systematic review by Aleksandra Anna Kajdas, Marcin Kleibert, Anne Katrine Normann, Krzysztof Krasuski, Ditte Søndergaard Linde, Dorota Szostak-Węgierek

“…Consequently, patients who were not using CNIs had a lower prevalence of hypomagnesaemia, hyperkalaemia, and metabolic acidosis compared to those treated with CNIs. …”
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Preservative-free therapy for glaucoma after corneal refractive surgery by A.A. Antonov, I.V. Kozlova, T.S. Mitichkina, I.I. Vedmedenko

“…In these patients, glaucoma is a specific condition because of low significance of classical screening and diagnostic tools. IOP-lowering treatment should not affect ocular surface but provide a stable IOP level. …”
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A Community-Based Intervention for Mental Health and Wellbeing in Pregnancy and Postpartum: One Healthy Start Site’s Story by Sampson M, Xu W, York FN, Roberson J

“…Healthy Start (HS) programs around the country seek to lower the risk of maternal mortality through services that screen for and address social determinants of health, including mental health. …”
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Short-term Effects of Sling Exercise Combined with Massage on the Treatment of Neck Type Cervical Spondylopathy by LI Jianfei, ZHAO Hong, CHEN Qian, LI Li, ZHANG Deqi

“…Further correlation analysis showed that the MPQ scores was negatively correlated with MF value (left: <italic>r</italic>=-0.626, <italic>P</italic>&lt;0.05; right: <italic>r</italic>=-0.695, <italic>P</italic>&lt;0.05); besides the NDI scores decreased with the increase of MF value (left: <italic>r</italic>=-0.692, <italic>P</italic>&lt;0.05; right: <italic>r</italic>=-0.491, <italic>P</italic>&lt;0.05), and the average MF value on the right was lower than that on the left.ConclusionSling exercise combined with massage can significantly reduce the patient's pain, activate and strengthen the neck muscles, improve the neck function of patients. …”
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Artificial intelligence-assisted clinical decision support for childhood asthma management: A randomized clinical trial. by Hee Yun Seol, Pragya Shrestha, Joy Fladager Muth, Chung-Il Wi, Sunghwan Sohn, Euijung Ryu, Miguel Park, Kathy Ihrke, Sungrim Moon, Katherine King, Philip Wheeler, Bijan Borah, James Moriarty, Jordan Rosedahl, Hongfang Liu, Deborah B McWilliams, Young J Juhn

“…Mean health care costs with 95%CI of children during the trial (compared to before the trial) in the intervention group were lower than those in the control group (-$1,036 [-$2177, $44] for the intervention group vs. +$80 [-$841, $1000] for the control group), though there was no significant difference (p = 0.12). …”
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Depressive symptoms among the oldest-old in China: a study on rural-urban differences by Chaoqun Hu, Qinqin Jiang, Yuan Yuan, Bing Hou, Zhe Zhao, Yijun Liu, Jinhai Sun, Lei Yuan

“…., health education, improving medical security, and providing sports venues and equipment) to improve mental health and lower the risk of depression among the oldest population.…”
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Active ingredients and mechanisms of peony seed blended oil in diabetes treatment using Kunming mice: Insights from GC–MS, network pharmacology, and experimental verification by Yuning Gu, Fengliang Zhong, Tiantian Sun, Zirui Chang

“…Soybean oil, rich in linoleic acid, plays a crucial role in lowering blood lipids and cholesterol, which helps prevent cardiovascular diseases. …”
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The effect of irrigation practice and water consumption using aqua-crop by M.D. Teweldebrihan, M.O. Dinka

“…This seemingly contradictory finding can be explained by diminishing returns: deficit irrigation may result in slightly lower yields but higher water efficiency, highlighting the importance of considering both yield and water use efficiency when making long-term irrigation decisions. has highlighted the disparity between projected and actual crop yields, underscoring the significance of incorporating practical factors into the simulation of irrigation techniques. …”
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JAUNOSIOS KARTOS KATALIKŲ INTELEKTUALŲ POŽIŪRIS Į FAŠIZMĄ IR NACIONALSOCIALIZMĄ TARPUKARIO LIETUVOJE by Valdas Pruskus

“…This salvation ought to be realized through a mass extermination of races of lower level, first of all, Jews. The theory of race inferiority preached by the Nazi and used by them as foundation of their activities, was antiscientific, and this was persuasively proved in the study of M. …”
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Calibration and Verification of the AquaCrop Model in Simulating the Yield, Dry Matter and Water Productivity of Grain Corn (Zea mays L.) under Different Irrigation Methods and Nit... by zhaleh zarei, Hassan Heidari, Saeid Jalali Honarmand, Ali Bafkar

“…AquaCrop simulation results showed that the model was able to simulate water productivity better than yield and total biomass so the coefficient of determination (R2) related to water productivity, yield, and biomass of maize was obtained as 0.82, 0.52, and 0.54 respectively.ConclusionThe simulation of yield, dry matter, and water productivity in the calibration and verification stage was lower than the actual value in all treatments. The biggest difference between the observed and simulated values of yield, biomass and water productivity was observed in the wick treatment (first and second year). …”
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Asociación entre burnout y calidad asistencial en atención primaria by Kilian Griñan Ferre, Joan Torras Borrell, Jordi Aparicio Freixa

“…Conclusions: Family physicians with burnout have a lower EQA value, which is not associated with age, sex or years of experience, but with the emotional exhaustion suffered.…”
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Optical coherence tomography in differential diagnosis of optic neuropathy of various genesis by S.I. Zhukova, D.Yu. Samsonov, T.N. Yur’eva, T.V. Prozorova

“…</p> <p> <b>Results: </b>the most pronounced RNFL alterations were observed in lower and temporal quadrants (GON patients); upper and nasal quadrants (ischemia patients); and in a temporal quadrant (MS patients). …”
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A Dynamic Adaptive Ensemble Learning Framework for Noninvasive Mild Cognitive Impairment Detection: Development and Validation Study by Aoyu Li, Jingwen Li, Yishan Hu, Yan Geng, Yan Qiang, Juanjuan Zhao

“…Specifically, compared with healthy individuals, patients with MCI exhibited a longer skin conductance response decay time during cognitive testing (P<.001), a lower percentage of continuous normal-to-normal intervals exceeding 50 milliseconds (P<.001), and higher LF/HF (P<.001), accompanied by greater variability. …”
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Association between insulin resistance indices and outcomes in patients with heart failure with preserved ejection fraction by Weicheng Ni, Ruihao Jiang, Di Xu, Jianhan Zhu, Jing Chen, Yuanzhen Lin, Hao Zhou

“…Additionally, the TyG-BMI index revealed a U-shaped correlation with MACE, indicating that both an elevated and a lower TyG-BMI index were associated with an increased risk. …”
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Clinical Efficacy of Muscle Energy Technology Combined with Conventional Rehabilitation Therapy on Patients with Chronic Non-Specific Neck Pain by ZHENG Kun, YANG Haolun, JIA Chengsen, ZHANG Liming

“…Compared with the control group, VAS score was significantly lower in the observation group after treatment, CSR20 score was significantly higher, and the differences were statistically significant (<italic>P</italic>&lt;0.05). …”
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Effects of Metabolic Factors on Left Ventricular Diastolic Function in Patients with Obstructive Sleep Apnea by Zhou YF, Chen SH, Wang WD, Chen JL, Cai PY, Li MM, Lin YL, Li WQ, Huang DH, Li J, Li YT, Lin HL

“…Measurements included nocturnal polysomnography, biochemical testing, and transthoracic echocardiography data.Results: The AHI in the MS group was higher (30.24± 21.69 vs 23.19± 17.65, p< 0.001) and the lowest oxygen saturation at night was lower (77.67± 9.23 vs 80.59± 9.26, p< 0.001) than those in the non-MS group. …”
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Dietary Cinnamaldehyde Enhances Growth Performance, Digestion, Immunity, and Lipid Metabolism in Juvenile Fat Greenling (Hexagrammos otakii) by Yixin Gu, Jian Han, Wenjie Wang, Yu Zhan, Huijie Wang, Wenyuan Hua, Yue Liu, Yafeng Guo, Zhuang Xue, Wei Wang

“…The juvenile H. otakii-fed dietary CNE had lower triglycerides (TG) and total cholesterol (TCHO) levels in the serum than fish-fed CNE-free diets (P<0.05). …”
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Effects of Duhuo Jisheng Decoction on Calcium Homeostasis and Apoptosis of Chondrocytes under Endoplasmic Reticulum Stress by Qing LIN, Wenyi WANG, Danhong PAN, Yanfeng HUANG, Changlong FU, Jinxia YE

“…Objective:To observe the effect of Duhuo Jisheng decoction on the balance of calcium homeostasis and apoptosis of chondrocytes under endoplasmic reticulum stress(ERS), and to preliminarily explore its mechanism of preventing and treating osteoarthritis.Methods:A steady chondrocyte in vitro culture system was established by using 4-week-old SD rat knee cartilage, and identify the third generation chondrocyte by toluidine blue staining.The 25 μmol/L Thapsigargin(TG)was used to induce chondrocyte in vitro culture to produce endoplasmic reticulum stress(ERS), incubate it in Duhuo Jisheng Decoction(100, 200, 400 μg/mL)for 24 hours after induction.The cells were divided into the blank group, the model group, the low-dose Duhuo Jisheng decoction group, the medium-dose Duhuo Jisheng decoction group, and the high-dose Duhuo Jisheng decoction group.Then morphological changes of chondrocytes were observed respectively by inverted microscope, viability of chondrocyte in each group was examined by CCK-8 method, chondrocyte apoptosis was observed by Hoechst 33342 staining and real-time dynamic changes of intracellular Ca²⁺concentration was examined by double turntable laser confocal microscope.Results:①The morphology of chondrocytes: the cells in the blank group grew in a single-layer paving stone shape, while the cells in the model group increased in a polygonal shape, the pseudopodia increased, the gaps widened, and the number of cells decreased significantly.Compared with the model group, the number of cells in the three dose groups of Duhuo Jisheng decoction(100, 200, 400 μg/mL)increased significantly and the cytoplasm was uniform.The activity of chondrocytes in each group: compared with the blank group, the survival rate of the model group was lower, and the difference was statistically significant(<italic>P</italic>&lt;0.05).The absorbance of each concentration group of Duhuo Jisheng decoction increased with the increase of concentration, and the difference was statistically significant compared with the model group(<italic>P</italic>&lt;0.05).③Apoptosis of chondrocytes: the number of apoptosis in the model group was significantly increased, and the degree of pyknosis of the nucleus was obvious, and some of them were a high density of bright blue or half moon-shaped.The number of apoptotic cells in each dose group of Duhuo Jisheng decoction was significantly reduced, only a few apoptotic cells showed a high density of bright blue or half-moon shape, and the number of apoptosis decreased with the increase of the concentration of Duhuo Jisheng decoction, showing a certain dose-effect relationship.④The changes of intracellular calcium ion concentration: the calcium ion fluorescence intensity of the cells in the blank group was weaker and more uniform, maintaining a stable state.The calcium ion release of the model group was significantly increased, and the fluorescence intensity was enhanced.The fluorescence spectrum showed that calcium sparks were more frequent.Compared with the blank group, the difference was statistically significant(<italic>P</italic>&lt;0.05).Chondrocytes in the medium and high-dose Duhuo Jisheng decoction groups could quickly return to calcium homeostasis, and calcium sparks were significantly reduced.Although there were still some calcium sparks in the low-concentration Duhuo Jisheng decoction group, the fluorescence intensity was significantly weaker than the model group.Conclusion:Duhuo Jisheng decoction has an inhibitory effect on the apoptosis of chondrocyte induced by TG, the mechanism may be that Duhuo Jisheng decoction can alleviate endoplasmic reticulum stress by regulating calcium balance, thus inhibiting the apoptosis of chondrocyte.…”
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