Optimization of chemical transfection in airway epithelial cell lines by Tony J. F. Guo, Wan Yi Liang, Gurpreet K. Singhera, Jasmine Memar Vaghri, Janice M. Leung, Del R. Dorscheid

“…In NCI-H292, jetOPTIMUS yielded a lower transfection efficiency (22.6 ± 1.2%) with a significant reduction in viability (28.3 ± 0.9%, p < 0.0001). …”
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High SUVs Have More Robust Repeatability in Patients with Metastatic Prostate Cancer: Results from a Prospective Test-Retest Cohort Imaged with 18F-DCFPyL by Rudolf A. Werner, Bilêl Habacha, Susanne Lütje, Lena Bundschuh, Takahiro Higuchi, Philipp Hartrampf, Sebastian E. Serfling, Thorsten Derlin, Constantin Lapa, Andreas K. Buck, Markus Essler, Kenneth J. Pienta, Mario A. Eisenberger, Mark C. Markowski, Laura Shinehouse, Rehab AbdAllah, Ali Salavati, Martin A. Lodge, Martin G. Pomper, Michael A. Gorin, Ralph A. Bundschuh, Steven P. Rowe

“…High SUVs showed significantly improved wCOV relative to lower SUVs (P<0.0001), indicating that high SUVs are more repeatable, relative to the magnitude of the underlying SUV. …”
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Ultra-fast [18F]florbetapir PET imaging using the uMI Panorama PET/CT system by Xueqian Yang, Meiqi Wu, Menglin Liang, Haiqiong Zhang, Bo Li, Chenhui Mao, Liling Dong, Yuan Wang, Haiqun Xing, Chao Ren, Zhenghai Huang, Qingxiang Wen, Qi Ge, Zhengqing Yu, Feng Feng, Jing Gao, Li Huo

“…Subjective visual diagnosis by two physicians yielded consistent accuracy for G10min, G2min, and G1min groups, but lower specificity for G45s and G30s groups. The objective detection of Aβ status by cortex SUVr across all scan durations maintained perfect discriminatory efficiency and relatively high effect size (Hedge’s G: 2.48–2.54). …”
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Changes in muscle performance among older adults with myeloid malignancies engaging in a mobile health (mHealth) exercise intervention: a single arm pilot study by Marielle Jensen-Battaglia, Po-Ju Lin, Chandrika Sanapala, Erin E. Watson, Jason H. Mendler, Jane Liesveld, Ying Wang, Elisabeth Hayward, Marissa LoCastro, Soroush Mortaz, Richard F. Dunne, Karen Mustian, Kah Poh Loh

“…Clinical exercise physiologists provided instruction and ongoing support. Upper and lower extremity peak torque (maximum force, newton-meters, Nm), total work (force over entire movement, Nm), and average power (speed of force, watts, W) were assessed using the BIODEX System 4 isokinetic dynamometer. …”
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Which muscle is the external rotation compensator after superior capsular reconstruction? by Nattakorn Mahasupachai, MD, Nobuyuki Yamamoto, MD, PhD, Atsushi Arino, MD, Jun Kawakami, MD, PhD, Rei Kimura, MD, Toshimi Aizawa, MD, PhD

“…Of these patients, 28 who met the following inclusion criteria were retrospectively reviewed: (1) massive rotator cuff tears, including the supraspinatus and infraspinatus, (2) severe muscle atrophy and fatty change, (3) intact or reparable subscapularis tendon, and (4) Hamada of grade 3 or lower. Posterior deltoid and teres minor volume were measured using open-source medical image processing software preoperatively and 1-year postoperatively. …”
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Construction and Comparison of Machine Learning-Based Risk Prediction Models for Major Adverse Cardiovascular Events in Perimenopausal Women by Chen A, Chang X, Bian X, Zhang F, Ma S, Chen X

“…Ovarian function declines in perimenopausal women and lower estrogen levels lead to changes in the function of various organs, which may lead to cardiovascular disease. …”
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Increased DHEAS and Decreased Total Testosterone Serum Levels in a Subset of Men with Early-Onset Androgenetic Alopecia: Does a Male PCOS-Equivalent Exist? by Rossella Cannarella, Rosita A. Condorelli, Federica Dall’Oglio, Sandro La Vignera, Laura M. Mongioì, Giuseppe Micali, Aldo E. Calogero

“…Group 1 had higher BMI (27.9 ± 3.8 vs. 23.7 ± 3.8 ml; P<0.05), fat-mass percentage (17.5 ± 4.1 vs. 13.2 ± 5.3; P<0.05), HOMA index (2.5 ± 1.8 vs. 1.5 ± 0.7; P<0.05), DHEAS (323.3 ± 112.6 vs. 257.8 ± 107.1 μg/dl; P<0.05), seminal fluid volume (4.2 ± 2.8 vs. 2.8 ± 1.3 ml; P<0.05), lower TT (5.16 ± 1.70 vs. 6.47 ± 4.30 ng/ml; P=0.016), and left TV (12.3 ± 2.8 vs. 15.0 ± 4.3 ml; P<0.05) compared to controls. …”
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Comparison of TAP block and epidural analgesia for postoperative analgesia after robotic-assisted radical prostatectomy by O.O. Volkov, Lutsenko V.V., M.O. Plis, M.V. Pavlenko, Krishtafor D.A.

“…A direct medium strength significant correlation was found between the method of analgesia and weakness in one of the lower limbs at the time of mobilization (r=0.69; p=0.039), a direct medium strength significant correlation was found between the size of the prostate and the time to tracheal extubation (r=0.39; p=0.041). …”
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Lenvatinib Therapy in Patients with Unresectable Hepatocellular Carcinoma in Real Clinical Practice by V. V. Petkau, A. V. Sultanbaev, K. V. Menshikov, A. S. Antipin, M. V. Volkonsky, V. M. Filippova, Yu. V. Vasilyeva, A. A. Tarkhanov, M. R. Mukhitova, M. Zh. Murzalina, A. R. Safarova

“…Patients with macroscopic portal vein invasion had a significantly lower PFS compared with those lacking this complication: 3.97 (0.00-8.07) vs. 11.1 (8.46-13.7), p = 0.053. …”
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Effect of Muscle Energy Technique Combined with Conventional Rehabilitation Therapy on Elderly Patients with Knee Osteoarthritis by FAN Jingjing, HUANG Lihua, XU Yiming, LIU Kun, FANG Ping

“…Compared with the control group at the same time, the WOMAC joint pain, joint stiffness, activity of daily living score and total WOMAC score in the observation group were significantly lower after treatment for four weeks and after treatment six months (P&lt;0.05). ② ROM, PT and PT/BW: Compared with that before treatment, ROM, PT and PT/BW of both groups were significantly higher after treatment for four weeks (P&lt;0.05). …”
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Analysis and Validation of Autophagy-Related Gene Biomarkers and Immune Cell Infiltration Characteristic in Bronchopulmonary Dysplasia by Integrating Bioinformatics and Machine Lea... by Xiao S, Ding Y, Du C, Lv Y, Yang S, Zheng Q, Wang Z, Zheng Q, Huang M, Xiao Q, Ren Z, Bi G, Yang J

“…Finally, the IHC result in mice showed that expression of PES1, BRX1, RRP9, JUN, NR4A1 was lower in the hyperoxia group compared to the normoxia group.Conclusion: BRIX1, JUN, PES1, NR4A1, RRP9, may be promising therapeutic targets for BPD. …”
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Degradation of low-density polyethylene by a novel strain of bacteria isolated from the plastisphere of marine ecosystems by F.A. Febria, A. Syafrita, A. Putra, H. Hidayat, C. Febrion

“…Fourier transform infrared observations showed variations in transmittance and wavenumbers, indicating changes in chemical bonds or functional groups in the low-density polyethylene film which caused it to become brittle and break down into smaller fragments with a lower molecular weight, making it easier for bacteria to digest. …”
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Identifying Community-Built Environment’s Effect on Physical Activity and Depressive Symptoms Trajectories Among Middle-aged and Older Adults: Chinese National Longitudinal Study by Kaili Zhang, Bowen Huang, Prasanna Divigalpitiya

“…ResultsIn the 2015 and 2018 waves, higher low-intensity leisure-time physical activity (LTPA) was associated with lower depressive symptoms (β=–.025, P=.01 and β=–.027, P=.005, respectively). …”
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The Effects of Artificial vs. Natural Rearing on Growth Performance, Thyroid Hormone Levels, Locomotor Activity, Carcass Traits and Meat Quality Characteristics in Chios Lambs by Panagiotis Simitzis, Georgia Alexopoulou, Eftychis Karampekos, Konstantina Linardopoulou, Anargyros Rigakis, Niki Stamelou, Michael Goliomytis, Iosif Bizelis, Ioannis Bossis

“…Levels for triiodothyronine (T3), thyroxine (T4) and the free form of T3 (FT3) were greater, whereas the standing percentage was lower in NR compared with AR lambs (<i>p</i> < 0.05). …”
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Integrated microbiome, transcriptome and metabolome insight into the alleviating mechanisms of sheep milk in a DSS-induced colitis mouse model by Wenna Yao, Ruilin Du, Shuo Yan, Teligun Bao, Huimin Zhang, Fang Yang, Yue Xue, Yulong Zhao, Siqin Bao, Xihe Li, Yongli Song

“…In the DSS group, LGR5, KI67, and MUC2 were significantly lower than in the CON group, but the SM treatment increased these protein expression levels. …”
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THE ORGANIZATION WORKS TO IMPROVE THE CLINICAL AND ECONOMIC OUTCOMES OF CARE FOR PROSTATE CANCER by O. I. Apolikhin, A. V. Sivkov, I. V. Chernishov, M. I. Katibov, O. V. Zolotukhin, I. A. Shaderkin, S. A. Leonov, D. A. Vojtko, M. Y. Prosyannikov

“…The purpose of this stage is a screening questionnaire for men of Voronezh region between the ages of 45 to 74 years using a modified international questionnaire lower urinary tract symptoms (IPSS) and nomograms individual risk of prostate cancer (SWOP №1).            …”
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Association between demographic, clinical characteristics and severe complications by SARS-CoV-2 infection in a community-based healthcare network in Chile. by Javiera Leniz, Sam Hernández-Jaña, Mauricio Soto, Eduardo Arenas, Paula Margozzini, Francisco Suarez, Daniel Capurro, María Paulina Rojas, Claudia Bambs

“…Having two or more COVID-19 vaccine doses compared with no doses was associated with a lower risk of any hospital admission (HR 0.81; 95% CI 0.77-0.84), an ICU admission (HR 0.60; 95% CI 0.57-0.63) and death (HR 0.50; 95% CI 0.46-0.54). …”
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Digital Surveillance of Mental Health Care Services in Saudi Arabia: Cross-Sectional Study of National e-Referral System Data by Abdullah A Alharbi, Nawfal A Aljerian, Meshary S Binhotan, Hani A Alghamdi, Ali K Alsultan, Mohammed S Arafat, Abdulrahman Aldhabib, Yasser A Alaska, Eid B Alwahbi, Mohammed A Muaddi, Ahmad Y Alqassim, Ronnie D Horner

“…The utilization of the mental health e-referral system varied across regions, with the Northern Border and Albaha regions showing the highest rates, while Madinah, Eastern, and Riyadh regions demonstrated lower use. Temporal analysis showed almost similar monthly patterns in 2020 and 2021. …”
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Tobacco Use, Risk Perceptions, and Characteristics of Adults Who Used a Heated Tobacco Product (IQOS) in the United States: Cross-Sectional Survey Study by Hui G Cheng, Brendan Noggle, Andrea R Vansickel, Edward G Largo, Pierpaolo Magnani

“…Among all AUIs, over 563 (81.8%) had never used a cessation treatment or had not used it in the past 12 months, and 555 (80.7%) AUIs demonstrated a correct understanding of the MRTP message and AUIs perceived THS as having a lower risk than cigarettes (43.8 vs 64.4 on a 100-point composite score scale). …”
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Prevalence and determinants of full vaccination coverage according to the national schedule among children aged 12–35 months in Ghana by Berhan Tekeba, Tadesse Tarik Tamir, Alebachew Ferede Zegeye

“…The full vaccination coverage according to the national schedule in Ghana was lower as compared to 90% coverage recommendation by World Health organization, and there is also in-equality among regions. …”
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