miR-223-3p Inhibits Antigen Endocytosis and Presentation and Promotes the Tolerogenic Potential of Dendritic Cells through Targeting Mannose Receptor Signaling and Rhob by Hao-Cheng Tang, Yin-Yan Lai, Jing Zheng, Hong-Yan Jiang, Geng Xu

“…FITC-OVA antigen uptake and cell surface markers in bone marrow-derived DCs (BMDCs) were analyzed by flow cytometry. BMDCs were transfected with the miR-223-3p mimic or inhibitor. …”
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Low-Dose Irradiation Differentially Impacts Macrophage Phenotype in Dependence of Fibroblast-Like Synoviocytes and Radiation Dose by Lisa Deloch, Jana Fuchs, Michael Rückert, Rainer Fietkau, Benjamin Frey, Udo S. Gaipl

“…For this, the bone marrow of hTNF-α tg mice was differentiated either with cytokines to obtain key macrophage phenotypes (M0, M1, and M2) or with supernatants (SN) of untreated or irradiated FLS. Flow cytometry analyses were used to analyse the impact of radiation (0.1, 0.5, 1.0, and 2.0 Gy) on the phenotype of macrophages in the presence or absence of SN of FLS. …”
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Relationships between muscle strength, lung function, and cognitive function in Chinese middle-aged and older adults: A study based on the China health and retirement longitudinal... by Yixuan Ma, Xinze Wu, Yinjiao Zhao, Weihao Hong, Yisheng Luan, Peiyu Song, Bing Zhang

“…Muscle strength was measured using normalized grip strength and chair-standing time, while lung function was evaluated using peak expiratory flow (PEF). Results: Total cognitive function scores exhibited significant correlations with grip strength, chair-standing time, and PEF. …”
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Supercritical CO2 Brayton Cycle Design for Small Modular Reactor with a Thermodynamic Analysis Solver by Pan Wu, Chuntian Gao, Yanping Huang, Dan Zhang, Jianqiang Shan

“…Increasing the dry cooling flow rate will be helpful to decrease the compressor inlet temperature. …”
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Inspiratory muscle training facilitates liberation from mechanical ventilation in subacute critically ill patients—a randomized controlled trial by Shu-Jane Wang, Tien-Pei Fang, Tien-Pei Fang, Daniel D. Rowley, Nan-Wei Liu, Jui-O Chen, Jui-Fang Liu, Jui-Fang Liu, Hui-Ling Lin, Hui-Ling Lin, Hui-Ling Lin

“…IMT intervention significantly reduced rapid shallow breathing index and improved respiratory muscle strength, with greater maximum inspiratory pressure (p < 0.01), maximum expiratory pressure (p = 0.03), and peak expiratory flow (p = 0.01). A moderate positive correlation was observed between IMT and increased creatinine levels (rs = 0.54, p = 0.01), whereas the no-IMT group showed a reduction.ConclusionIMT significantly shortened ventilator duration and improved respiratory muscle strength. …”
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Influence of injection technique, drug formulation and tumor microenvironment on intratumoral immunotherapy delivery and efficacy by Patrick Hwu, Ravi Murthy, Aung Naing, Sapna P. Patel, Simon Young, Alda Tam, Nina M. Muñoz, Malea Williams, Katherine Dixon, Crystal Dupuis, Amanda McWatters, Rony Avritscher, Soraya Zorro Manrique, Kevin McHugh, David Leach, Jeffrey D. Hartgerink, Punit Prakash, Rahul A. Sheth

“…The influence of varying needle design and hydrogel-based drug delivery on the immune response to a stimulator of interferon genes (STING) agonist was evaluated using flow cytometry and single cell RNA sequencing. We also evaluated the influence of tumor stiffness on drug injection distribution.Results Variations in needle design, specifically with the use of a multiside hole needle, led to approximately threefold improvements in intratumoral drug deposition relative to conventional end-hole needles. …”
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Pharmacological Vitamin C-induced high H2O2 generation mediates apoptotic cell death by caspase 3/7 activation in breast cancer tumor spheroids by Ali Mussa, Mahasin Hamid, Khalid Hajissa, Ahmad Hafiz Murtadha, Mohammad A. I. Al-Hatamleh, Noor Fatmawati Mokhtar, Vuk Uskoković, Magdalena Plebanski, Rohimah Mohamud, Rosline Hassan

“…Assessments were conducted to determine the cell viability, H2O2 levels, glutathione-to-glutathione disulfide (GSH/GSSG) ratios, and apoptosis. Both flow cytometry analyses of Annexin V/PI staining and caspase3/7 activity assay were used to check apoptosis. …”
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Isolation and Characterization of an Adult Stem Cell Population from Human Epidural Fat by Nedaa Al-Jezani, Roger Cho, Anand O. Masson, Brian Lenehan, Roman Krawetz, Frank G. Lyons

“…The cell surface receptor profile of HEF cells was examined by flow cytometry. HEF cells were also assayed through the collagen contraction assay. …”
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Mechanisms of N₂O Emission in Drip-Irrigated Saline Soils: Unraveling the Role of Soil Moisture Variation in Nitrification and Denitrification by Fang Zhang, Zhi Qu, Qian Zhao, Zixuan Xi, Zhen Liu

“…Therefore, during drip irrigation, the position and flow rate of the dripper should be controlled to reduce soil water saturation areas, maintain soil aeration, control soil moisture content below field holding capacity, promote the nitrification process, reduce N₂O emissions, and improve soil nitrogen use efficiency. …”
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Law enforcement activity, globalization and social morality in frameworks of mass culture (On the Example of Modern European TV-Shows on Law-Enforcements. Part 2) by Vovk V.

“…Special attention is paid to analyzing the sociocultural context within which modern mass culture exists (globalization, the spread of democracy, unification and standardization of life, compression of time, significant information flow, clip type of thinking, etc.). Results: the article shows that the spread of mass culture is due to the development of technologies and a change in the type of communication: from verbal-written to audiovisual (which only confirms the fundamental importance of sight and visual metaphor within European culture). …”
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Applications of Ultrasonic Brain Imaging and Transcranial Ultrasound Therapy in Brain Injury Rehabilitation by WU Yi

“…It can also be combined with EEG to simultaneously record the changes of the cerebral blood flow and neural activities, so as to conduct multi-dimensional evaluation of the neurovascular function after the occurrence of cerebrovascular disease. …”
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Mitigating effects of Jiawei Chaihu Shugan decoction on necroptosis and inflammation of hippocampal neurons in epileptic mice by Qin Wang, Baijun Qin, Han Yu, Jiawei Zeng, Jingjing Fan, Qiong Wu, Rong Zeng, Haichun Yu, Xian Zhang, Mingfen Li, Yanying Zhou, Limei Diao

“…Viability and apoptosis were assessed via CCK-8 and flow cytometry. In vivo, 60 C57BL/6J mice were divided into six groups: control, model, carbamazepine, JWCHSGD, JWCHSGD + Sh Circ_Csnk1g3, and JWCHSGD + Sh NC. …”
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Pyrolysis-catalytic gasification of plastic waste for hydrogen-rich syngas production with hybrid-functional Ni-CaOCa2SiO4 catalyst by Tian Heng Qin, Guozhao Ji, Boyu Qu, Alan J McCue, Shaoliang Guan, Jos Derksen, Ye Shui Zhang

“…The different parameters (Ni loading, temperature, N2 flow rate and feedstock-to-catalyst ratio) have been investigated to optimise the H2 production. …”
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INCREASING EFFICIENCY OF REPAIRING, MANUFACTURING AND OPERATION OF THE TPP FACILITIES BY TECHNOLOGY OF GAS-THERMAL COATING AND LASER SURFACE MELTING by O. E. Grachev, V. M. Neuimin, D. V. Nasteka

“…The rotor blades work under conditions of intense power loading, their airfoil being erosion-corrosion destructed by the action of the moist-steam flow. Repairing companies employ quite a number of technologies to restore some of erosion-worn rotor blades. …”
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Alcohol intake exacerbates experimental autoimmune prostatitis through activating PI3K/AKT/mTOR pathway-mediated Th1 differentiation by Shun Xu, Shun Xu, Shun Xu, Jing Chen, Jing Chen, Jing Chen, Shaoyu Yue, Shaoyu Yue, Shaoyu Yue, Yifan Zhang, Yifan Zhang, Yifan Zhang, Shengyu Zhao, Shengyu Zhao, Shengyu Zhao, Yongtao Hu, Yongtao Hu, Yongtao Hu, Cheng Zhang, Cheng Zhang, Cheng Zhang, Wenrui Guan, Wenrui Guan, Wenrui Guan, Li Zhang, Li Zhang, Li Zhang, Ligang Zhang, Ligang Zhang, Ligang Zhang, Chaozhao Liang, Chaozhao Liang, Chaozhao Liang

“…Subsequently, proteomic analysis, flow cytometry, immunofluorescence, Western blotting, and immunohistochemistry were utilized to investigate the underlying mechanism involved both in vivo and in vitro.ResultsHE staining, ELISA, and behavioral experiments showed that alcohol exacerbated the severity of EAP in mice and patients. …”
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Can Primary Cardiac Myxofibrosarcoma Grow Quickly from Zero to a Size Leading to Left-Sided Heart Failure within 9 Months? by Levan Karazanishvili, Eduard Limonjiani

“…These tumors can silently grow and produce no or few symptoms until the tumor is large enough to obstruct blood flow. The definitive treatment is negative margin resection, if possible. …”
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Enhancing hydraulic fracturing efficiency through machine learning by Ali Karami, Ali Akbari, Yousef Kazemzadeh, Hamed Nikravesh

“…This process involves the creation of new fractures and the extension of existing ones within the rock by injecting a high-pressure fracturing fluid, which enhances the flow of hydrocarbons. To assess the efficiency and safety of HF, various factors such as fracture orientation, geometry, length, distribution, and stimulated reservoir volume are analyzed. …”
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اعتماد برنامج المکتبات والمعلومات بجامعة المنوفية : المشکلات والصعوبات by فاطمة خمیس

“…The study aimed to identify the problems and difficulties that the Librariesand Information Department faced when applying the standards, indicators,elements and characteristics of the evaluation and accreditation guide for theeducational program in higher education institutions and Al-Azhar through theexperience of accrediting the Library and Information Program at the University ofMenoufia.The study identified problems at the level of five main axes focused Thefirst axis focused on problems from a formal point of view, while the second axisdealt with coding at the level of standards, while the third axis represented theabsence of forms for questionnaires required for accreditation, while the fourthaxis devoted to problems at the level of procedures, and finally the fifth axisaddressed problems at the level of relationships between standards, Theresearcher used the Descriptive Analytical Methodology, as the researcheranalyzed the actual content of the actual application of the evaluation andaccreditation guide for the educational program in higher education institutionsand Al-Azhar through the experience of accrediting the library and informationprogram at the University of Menoufia , The study reached to identify thoseproblems in the above five axes, the most important of which are the presence ofindicators, elements and characteristics in other than their correct locations, therecurrence of coding at the level of the first three criteria under each of theprogram management axis and the axis of educational effectiveness, theabsence of models of questionnaires required to meet the criteria , The guidedoes not include flowcharts in which the starting point and the end point arespecified to meet the standard, the absence of a model procedural guide thatclarifies the steps of work within the standard and one of the most importantrecommendations of the study is the preparation of a model procedural guide bythe National Authority to ensure the quality of education and accreditationclarifies the method of work within Evaluation and accreditation guide for the  educational program in higher education institutions and Al-Azhar, preparing anew edition of the "evaluation and accreditation guide for the educationalprogram in higher education and Al-Azhar institutions taking into account thefollowing: Non-repetition of coding at the level of the first three criteria under boththe program management axis and the educational effectiveness axis and toinclude The new version of the guide provides flow charts that define a point Thestart and the end point to meet the standard…”
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Aerodynamic optimization of small diffuser Augmented Wind Turbines: A differential evolution approach by Turan Dias Oliveira, Luzia Aparecida Tofaneli, Alex Álisson Bandeira Santos

“…This work aims to study the impact of wind characteristics on the optimal aerodynamic design of a DAWT blade considering non-uniform flow generated using the diffuser. A new expression for the correction of thrust coefficients for high values of axial induction factor is proposed, so that it is suitable for the evaluation of turbines with and without diffusers. …”
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Derivation of pressure distribution models for horizontal well using source function by J.O. Oloro, E.S. Adewole

“…Despite these advantages, determination of pressure distribution expression is a problem because it involve 3D transient-flow that need to be solved. In this work, ten (10) models for pressure distribution for horizontal well under different boundary variation were derived following these steps for each of the models:(i) choosing a boundary condition for each axis (ii) selecting the appropriate source function for each axis and (iii)applying Newman product rule to arrive at the pressure expression. …”
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