Intranasal Testing and Treatment for Staphylococcus aureus With Intravenous Vancomycin and Intranasal Povidone-iodine Prior to Posterior Spinal Fusion: A Retrospective Cohort Study... by Jason Malone, DO, Alex Lee-Norris, DO, Austin Wynn, MD, Kaitlin Maher, PA-C, John Lovejoy, III, MD, Ryan Illgenfritz, MD, Margaret Baldwin, MD, Adriana Cadilla, MD, Kathryn Farrell, MSN, Emily Craver, MS

“…Hospital-wide bacterial rates in Group A compared to Group B were higher for all S. aureus species (33.8% vs 30.1%, P ​= ​0.0004), methicillin-sensitive S. aureus (24.6% vs 13.1 %, P ​< ​0.001) but lower for methicillin-resistant S. aureus (9.2% vs 17%, P ​= ​0.02). …”
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The physiological responses to volume-matched high-intensity functional training protocols with varied time domains by Jessica S. Smith, Jessica S. Smith, Gabriella F. Bellissimo, Gabriella F. Bellissimo, Fabiano T. Amorim

“…An interaction effect revealed that BLA was lower for the EMOM (6.5 ± 2.7 mmol/L) than the RFT (11.2 ± 2.1 mmol/L) post-exercise (p &lt; 0.00). …”
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Association between blood test indicators and atrial fibrillation in elderly patients aged 65 and above in the Central Jiangsu region: a cross-sectional study by Hao Liang, Shuai Zhang, Ye Zhu

“…After adjusting for relevant confounding factors, lower levels of albumin, and higher levels of direct bilirubin and uric acid were significantly associated with the occurrence of AF (P < 0.05). …”
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Management of Irritable Bowel Syndrome: Novel Approaches to the Pharmacology of Gut Motility by Carmelo Scarpignato, Iva Pelosini

“…Although it is unclear to what extent irritable bowel syndrome (IBS) symptoms represent a normal perception of abnormal function or an abnormal perception of normal function, many believe that IBS constitutes the clinical expression of an underlying motility disorder, affecting primarily the mid- and lower gut. Indeed, transit and contractile abnormalities have been demonstrated with sophisticated techniques in a subset of patients with IBS. …”
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Systematic Review with Network Meta-Analysis: Comparative Efficacy and Safety of Combination Therapy with Angiotensin II Receptor Blockers and Amlodipine in Asian Hypertensive Pati... by Dae Wook Lee, Mira Jung, Hye Won Wang, Zainah Khan, Philippe Pinton

“…All ARB-AML CTs had safety profiles comparable to AML monotherapy except TEL-AML, which had significantly lower odds of TEAEs (0.26 (95% CI: 0.087, 0.70)). …”
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Antimicrobial susceptibility testing of Dermabacter hominis by Tim Kintzinger, Dennis Knaack, Sören Schubert, Uwe Groß, Robin Köck, Frieder Schaumburg

“…All isolates were susceptible to vancomycin, rifampicin, and linezolid (100%, n = 30/30). Lower susceptibility rates were found for ampicillin (83%, n = 25/30) followed by ceftriaxone (37%, n = 11/30) and clindamycin (27%, n = 8/30). …”
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Wind–Wave Misalignment in Irish Waters and Its Impact on Floating Offshore Wind Turbines by Thomas Shanahan, Breiffni Fitzgerald

“…The investigation highlighted that in western coastal areas, average misalignment could reach <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msup><mn>57.95</mn><mo>∘</mo></msup></mrow></semantics></math></inline-formula>, while sheltered Irish Sea regions experienced lower values, such as <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msup><mn>23.06</mn><mo>∘</mo></msup></mrow></semantics></math></inline-formula>. …”
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Extended-release amphetamine (Dyanavel XR) is associated with reduced immediate-release supplementation in adults with ADHD, regardless of baseline patient variables: a retrospecti... by Joel L. Young, Richard N. Powell, Anna Powell, Lisa L. M. Welling, Lauren Granata, Jaime Saal, Margot Nash

“…Results Compared to the other amphetamine and methylphenidate ER medications, only Dyanavel XR resulted in lower IR supplementation at 90 days. This relationship held when controlling for baseline IR use. …”
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Assessing the feasibility of measuring residents’ quality of life in English care homes and the construct validity and internal consistency of measures completed by staff proxy: a... by Claire Goodman, Julienne Meyer, Karen Spilsbury, Barbara Hanratty, Rachael Carroll, Adam L Gordon, Gizdem Akdur, Anne Killett, Jennifer Burton, Ann-Marie Towers, Stacey Rand, Nick Smith, Sinead Palmer, Stephen Allan, Lucy Anne Webster

“…Feasibility (% missing by software provider and measure), % floor/ceiling effects (&gt;15% at lower/upper end of the scales), convergent or divergent construct validity (criterion of &gt;75% of hypotheses accepted) and internal consistency (Cronbach’s alpha ≥0.7) were assessed for all four measures.Results The ordinal EFA of QUALIDEM did not replicate the findings of previous research. …”
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Reproductive management and parity influence reproductive activity in a tropical buffalo herd by José Atilio Aranguren-Méndez, Rafael Román-Bravo, Ricardo A. Briceño-Rojas, Mauricio G. Briceño-Rojas, Eliani K. Núñez-Guerrero, Fernando P. Perea

“…Conception rate at first service was lower in period 1 (60.1%) than in period 2 (69.1%) (p<0.0001). …”
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Overlying strata movement law and rockburst prevention & control for fully mechanized top coal caving face in extra-thick coal seams by Hai Rong, Longyue He, Yadi Wang, Xiangzhi Wei, Shilong Wei, Suihan Yang, Jincheng Li, Linlin Chen

“…The goaf of the 12,220 working face in the north of the working face is a crucial reason for the support resistance of the upper part of the 12,240 working face being greater than that of the middle part and the middle part being greater than that of the lower part. When the working face advances 20–30 m, a distinct pressure accumulation area emerges in the middle of the working face and is regularly distributed as the working face advances. …”
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Geochemical signatures and nanomechanical properties of echinoid tests from nearshore habitats of Florida: environmental and physiological controls on echinoid biomineralization by Przemysław Gorzelak, Luis Torres Jr., Dorota Kołbuk, Tobias B. Grun, Michał Kowalewski

“…The inner galleried and coarse labyrinthic stereom typically exhibited a lower Mg/Ca ratio and nanohardness than the outer imperforate stereom layer that locally forms tubercles. …”
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A Multidisciplinary-Based and Bundle Intervention for Controlling Carbapenem-Resistant Organisms in Neurosurgery by Zhu W, Liang Y, Xu J, Weng C

“…The total detection rate of CRO strains was 52.25%, which was significantly lower than 66.45% before intervention (RR = 0.786; 95% CI, 0.678– 0.912; p < 0.05), and the incidence density of patients infected or colonized with CROs showed significant decrease from 18.75 per 1000 patient-days to 15.09 per 1000 patient-days (IRR = 0.563; 95% CI, 0.449– 0.707; p < 0.05).Conclusion: The multidisciplinary and bundle interventions based on PDCA cycle management tool had a good effect on the prevention and control of CROs in neurosurgery.Keywords: PDCA, carbapenem-resistant organisms, neurosurgery, intervention…”
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Targeting necroptosis in MCF-7 breast cancer cells: In Silico insights into 8,12-dimethoxysanguinarine from Eomecon Chionantha through molecular docking, dynamics, DFT, and MEP stu... by Maram B Alhawarri, Mohammad G Al-Thiabat, Amit Dubey, Aisha Tufail, Katreen Banisalman, Ghazi A Al Jabal, Eman Alkasasbeh, Esra'a Ibrahim Al-Trad, Bilal Harieth Alrimawi

“…Molecular docking revealed that SG-A exhibited a stronger affinity for MLKL (-9.40 kcal/mol) compared to the co-crystallized ligand (-6.29 kcal/mol), while its affinity for RIPK1 (-6.37 kcal/mol) and RIPK3 (-7.01 kcal/mol) was lower. MD simulations further demonstrated the stability of SG-A within the MLKL site, with RMSD values stabilizing between 1.4 and 3.3 Å over 300 ns, indicating a consistent interaction pattern. …”
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Effect of Tea Polyphenols, α-Lipoic Acid and Their Joint Use on the Antioxidant and Lipid Metabolism Performance of Hybrid Grouper (♀Epinephelus fuscoguttatus × ♂E. lanceolatu) Fed... by Xiangxiang Suo, Xiaobo Yan, Beiping Tan, Simiao Pan, Tao Li, Hao Liu, Weibin Huang, Shuang Zhang, Yuanzhi Yang, Xiaohui Dong

“…In contrast, the TL group had the highest fatty acid synthetase (FAS) activity (P<0.05). (5) The oil-red aspects of liver tissue displayed lipid particles in other groups were reduced to different degrees compared with FL group, and the OL group showed the best lipid-lowering effect. (6) Compared with the FL group, the relative expressions of FAS, acetyl-CoA carboxylase (acc), and apolipoprotein b-100 (apoB100) genes in the liver were decreased. …”
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Fractal Characteristics of Pore Structure of Longmaxi Shales with Different Burial Depths in Southern Sichuan and Its Geological Significance by Manping Yang, Yanyan Pan, Hongye Feng, Qiang Yan, Yanjun Lu, Wanxin Wang, Yu Qi, Hongjian Zhu

“…Burial depth can significantly impact the pore structure characteristics of shale. The Lower Silurian Longmaxi Shale in the Weiyuan block of the Sichuan Basin is a marine formation that we studied for deep shale gas exploration. …”
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A Rare Case of Arteriovenous Hemangioma Clinically Mimicking Pigmented Nevus by Sri Lestari, Tofrizal ., Yenny Raflis

“…She complained about a black pimple on the right lower arm since one month. Physical examination: there is a solitare black papule, with 0,3x0,4 mm, round shape, fine scales, well defined, regular border with irreguler surface.…”
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Studi Awal Deteksi COVID-19 Menggunakan Citra CT Berbasis Deep Learning by Windra Swastika

“…Abstract In December 2019, the COVID-19 virus spread to many countries, including Indonesia which later became a pandemic and caused serious problems because there was still no vaccine to prevent transmission. Tests of upper and lower respiratory tract specimens are now an effective method of finding whether a person is infected with COVID-19 or not. …”
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Evaluation of Retinal Nerve Fiber Layer Thickness, Electroretinogram and Visual Evoked Potential in Patients with Alzheimer’s Disease by Qi Zhe Ngoo, Wan Hazabbah Wan Hitam, Asrenee Ab Razak

“…The mean of the average, superior and inferior RNFL thickness were significantly lower in the AD group compared with control. There is also significant difference of PERG and PVEP parameters between AD and controls. …”
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DeepGenMon: A Novel Framework for Monkeypox Classification Integrating Lightweight Attention-Based Deep Learning and a Genetic Algorithm by Abdulqader M. Almars

“…Compared to the state-of-the-art (SOTA) models, DeepGenMon features a lightweight design that requires significantly lower computational resources and is easier to train with few parameters. …”
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