Rab21-Targeted Nano Drug Delivery System-Based FFPG for Efficient Paclitaxel Delivery to Inhibit Lung Cancer Progression by Jing Wang, Xueying Yan, Wenfei Wang, Shu Wang, Hongxiang Jiang, Xinhua Zhu, Zhehui Li, Defu Cai, Yonggang Xia

“…The uptake of the NDDS was observed by confocal microscopy and flow cytometry. Cytotoxicity, apoptosis, migration, and invasion experiments were used to evaluate the anti-tumor ability of the NDDS in vitro. …”
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Temporal Characteristics of Heat Waves and Cold Spells and Their Links to Atmospheric Circulation in EURO-CORDEX RCMs by Eva Plavcová, Jan Kyselý

“…The RCMs reproduce in general the observed circulation significantly conducive to heat waves and cold spells. Zonal flow reduces the probability of temperature extremes in both seasons, while advection of warm/cold air from the south-easterly/north-easterly quadrant plays a dominant role in developing heat waves/cold spells. …”
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Different MHC class I cell surface expression levels in diverse chicken lines, associations with B blood group, and proposed relationship to antigen-binding repertoire by Michael Kaiser, Jim Kaufman, Susan J. Lamont

“…In our study, erythrocytes from 6 diverse and highly inbred lines of chickens, a closed broiler line, and a highly advanced intercross line were evaluated for MHC class I antigen expression level by flow cytometry using monoclonal antibodies to chicken MHC class I molecules. …”
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Changes in PD-1 expression on T lymphocyte subsets and related immune indicators before and after definitive chemoradiotherapy for esophageal squamous cell carcinoma by Xueling Shi, Hongyu Zhao, Jiaqi Yu, Peng Cai, Shixiang Zhou, Ning Yang, Duojie Li

“…Before and after CRT, flow cytometry was used to detect thePD-1 expression in the peripheral blood and related immune indicators. …”
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Assessment and Optimization of Ecological Networks in Trans-Provincial Metropolitan Areas—A Case Study of the Xuzhou Metropolitan Area by Yijia Zhao, Peiyuan Zhang, Hao Xu, Wei Liu

“…The number of ecological corridors decreased, the average length of ecological corridors increased, the difficulty of biological flow increased, the connectivity of the ecological network structure decreased, and accessibility between source areas decreased. …”
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Solid lipid nanoparticles for increased oral bioavailability of acalabrutinib in chronic lymphocytic leukaemia by Swagata Sinha, Punna Rao Ravi, Makarand Somvanshi, S. R. Rashmi

“…Additionally, inhibition of lymph production and flow by administering cycloheximide resulted in 46.01% decrease in the overall absorption of ACP-SLNs, indicating the significance of lymphatic uptake process in the oral absorption of ACP-SLNs. …”
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Using the YOUTUBE portal to train future studio managers abstract arts and crafts by Ekaterina O. Kunyaevа

“…Currently, the rapid growth of the scientific information flow, the volume of which increases every year, encourages the search for new effective methods, methods and means of training that would allow students to present more information for the same unit of study time and prepare high-level professionals. …”
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Green biosynthetic silver nanoparticles from Ageratum conyzoides as multifunctional hemostatic agents: Combining hemostasis, antibacterial, and anti-inflammatory properties for eff... by Yang Li, Yinfeng Tan, Huange Zhao, Shiting Chen, Azadeh Nilghaz, Rong Cao, Songlin Zhou

“…Subsequent experiments including scanning electron microscopy, flow cytometry, western blotting, and network pharmacology analysis have revealed that AC-AgNPs can cause platelet activation and aggregation, stimulated kallikrein-kinin system, shorten activated partial thromboplastin and prothrombin time, and increase fibrinogen content. …”
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Simulation study on catalytic oxidation of low concentration mine gas in an oxidation device by Yuhang Liu, Xijian Li, Qi Xiao, Xingfa Jiang, Weilai Dong, Xianyong Chen, Yuyan Feng

“…To study the combustion and heat transfer reactions of low-concentration coal mine methane in a catalytic oxidation device, a numerical simulation approach was employed to establish a model of the catalytic oxidation device that includes periodic boundary conditions, methane combustion mechanisms, and turbulent-laminar flow characteristics. The core focus of this study is on the dynamic changes in the bed temperature of the oxidation device, the temperature of the extracted hot air, and the methane conversion rate. …”
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D-mannose promotes diabetic wound healing through inhibiting advanced glycation end products formation in keratinocytes by Jialiang Luo, Tianxing Wu, Jing Zhang, Zhicheng Liang, Weijie Shao, Di Wang, Lei Li, Daming Zuo, Jia Zhou

“…Apoptotic cells were assessed by flow cytometry and Western blotting. Inflammatory cytokines and cellular differential gene expression levels were measured by real-time PCR. …”
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The Empty Bower and the Lone Fountain by Domenic Leo

“…In the Fonteinne, two images of a fountain as subject matter, devoid of figures, break the narrative flow. This literally forces the viewer to focus on the subject matter rather than passively following the verbal action taking place around it. …”
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Hard-coded backdoor detection method based on semantic conflict by Anxiang HU, Da XIAO, Shichen GUO, Shengli LIU

“…The current router security issues focus on the mining and utilization of memory-type vulnerabilities, but there is low interest in detecting backdoors.Hard-coded backdoor is one of the most common backdoors, which is simple and convenient to set up and can be implemented with only a small amount of code.However, it is difficult to be discovered and often causes serious safety hazard and economic loss.The triggering process of hard-coded backdoor is inseparable from string comparison functions.Therefore, the detection of hard-coded backdoors relies on string comparison functions, which are mainly divided into static analysis method and symbolic execution method.The former has a high degree of automation, but has a high false positive rate and poor detection results.The latter has a high accuracy rate, but cannot automate large-scale detection of firmware, and faces the problem of path explosion or even unable to constrain solution.Aiming at the above problems, a hard-coded backdoor detection algorithm based on string text semantic conflict (Stect) was proposed since static analysis and the think of stain analysis.Stect started from the commonly used string comparison functions, combined with the characteristics of MIPS and ARM architectures, and extracted a set of paths with the same start and end nodes using function call relationships, control flow graphs, and branching selection dependent strings.If the strings in the successfully verified set of paths have semantic conflict, it means that there is a hard-coded backdoor in the router firmware.In order to evaluate the detection effect of Stect, 1 074 collected device images were tested and compared with other backdoor detection methods.Experimental results show that Stect has a better detection effect compared with existing backdoor detection methods including Costin and Stringer: 8 hard-coded backdoor images detected from image data set, and the recall rate reached 88.89%.…”
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Antiangiogenic therapy with recombinant human endostatin may improve blood perfusion of cervical node with necrosis in nasopharyngeal carcinoma patients: a preliminary study by usi... by Zhendong Yang, Huimin Xiao, Xigui Li, Zhuxin Wei, Min Kang, Rensheng Wang, Jianyuan Huang

“…The MTT of day 5 after AT became obviously shorter than the MTT of the day before AT [28.08 ± 3.03 (s) vs. 33.76 ± 6.20 (s), p = 0.001].ConclusionThese results revealed that the blood volume and the blood flow velocity in the microvessels of the CNN increased after AT, indicating that AT with RHES may improve blood perfusion in the CNN of NPC, thus providing valuable insights for the clinical application of AT combined with RT and/or chemotherapy in NPC patients with CNN. …”
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Frequency and factors associated with loss to follow-up in newly diagnosed rheumatoid arthritis patient: a single-centre study by Sumariyono Sumariyono, Rudy Hidayat, Faisal Parlindungan, Suryo Anggoro Kusumo Wibowo, Anna Ariane, Johanda Damanik, Abirianty Priandani Araminta, Ryzkianty Annis Nurdin

“…The reasons for LTFU were distance from house to hospital constraints (76%), busy (56%), transportation constraints (38%), dissatisfaction with the outpatient clinic service (21%), lack of information about their disease (18%), having other comorbidities that compelled them to go to another department’s clinic (15%), difficulties understanding the clinic registration flow system (9%), and having minimal symptoms (6%). …”
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A reliable analytical procedure to determine the carbon isotopic signature of CO₂-bearing COH fluids generated in petrological experiments by L. Toffolo, L. Minopoli, E. Ferrari, S. Tumiati

“…The optimal values of the carrier gas flow in the QMS, sampling times, and chromatography column temperature for IRMS are determined. …”
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Overcoming the Silencing of Doxycycline-Inducible Promoters in hiPSC-derived Cardiomyocytes [version 1; peer review: 1 approved, 2 approved with reservations] by Michelle Guichardaz, Elisa Balmas, Alessandro Bertero, Sveva Bottini

“…Transgene expression was assessed via flow cytometry and real-time quantitative PCR. Results TRE3VG exhibited higher activity than T11, but both were prone to silencing. …”
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Vicarious trauma, coping strategies and nurses' health outcomes: An exploratory study by Ilenia Piras, Vanessa Usai, Paolo Contu, Maura Galletta

“…Literature showed that pandemics influenced the nurses' stress and psychosocial health due to poor rest, high work overloads, a lack of control over the patient flows, and a frequent isolation from family. Under these circumstances, nurses experienced severe psychological and mental stressors that generated mental health problems. …”
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Anticancer Activity of Holothuria Leucospilota-Derived Saponin on MKN45 Gastric Cancer Cell via Upregulation of CDH1 Hub Gene by Khadijeh Sadegh, Amirhossein Ahmadi, Ahmad Shadi, Ahmad Ghasemi

“…The effect of HLBS on MKN45 cell migration, cell cycle, and apoptosis was assessed using a scratch assay, and flow cytometry, respectively. Hub genes of GC were identified through bioinformatics analysis. …”
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Direct visualization of peptide/MHC complexes at the surface and in the intracellular compartments of cells infected in vivo by Leishmania major. by Eric Muraille, Pierre Gounon, Julie Cazareth, Johan Hoebeke, Christoph Lippuner, Ana Davalos-Misslitz, Toni Aebischer, Sylviane Muller, Nicolas Glaichenhaus, Evelyne Mougneau

“…The presence of I-Ad/LACK complexes at the surface of dendritic cells, but neither on the plasma membrane of macrophages nor eosinophils was independently confirmed by flow cytometry and by incubating sorted phagocytes with highly sensitive LACK-specific hybridomas. …”
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Mechanically stable polymer networks incorporating polymeric ionic liquids for enhanced conductivity in solid-state electrolytes by Sezer Özenler, Nataliya Kiriy, Upenyu L. Muza, Martin Geisler, Anton Kiriy, Brigitte Voit

“…Molecular weights of the PIL samples, ranging from 30 to 40 kDa, were determined using a complimentary combination of thermal field-flow fractionation (ThFFF) and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) analysis. …”
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