Last-millennium volcanic forcing and climate response using SO₂ emissions by L. R. Marshall, L. R. Marshall, L. R. Marshall, A. Schmidt, A. Schmidt, A. Schmidt, A. P. Schurer, N. L. Abraham, N. L. Abraham, L. J. Lücke, R. Wilson, K. J. Anchukaitis, G. C. Hegerl, B. Johnson, B. L. Otto-Bliesner, E. C. Brady, M. Khodri, K. Yoshida

“…In UKESM1, we find that the simulated volcanic forcing differs considerably from the PMIP4 dataset used in models without interactive aerosol schemes, with marked differences in the hemispheric spread of the aerosol, resulting in lower forcing in the NH when <span class="inline-formula">SO₂</span> emissions are used. …”
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Microwave ablation vs. single-needle radiofrequency ablation for the treatment of HCC up to 4 cm: A randomized-controlled trial by Katsutoshi Sugimoto, Kento Imajo, Hidekatsu Kuroda, Go Murohisa, Kazue Shiozawa, Kentaro Sakamaki, Takuya Wada, Hirohito Takeuchi, Kei Endo, Tamami Abe, Takashi Matsui, Takahiro Murakami, Masato Yoneda, Atsushi Nakajima, Shigehiro Kokubu, Takao Itoi

“…The proportion of lesions with LTP at the 2-year follow up was significantly lower in the MWA group (20 [16.4%] lesions) than in the RFA group (38 [30.4%] lesions) (risk ratio, 0.54; p = 0.007). …”
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Buffalo feed efficiency: optimizing the use of fibrous biomass carbon to enhance production while mitigating rumen methane emission by Metha Wanapat

“…Concerning the rumen microbiomes of buffaloes, it has been reported that they were highly diversified and relatively higher-abundant compared to cattle, leading to enhanced total volatile fatty acids (VFAs) and lower methane production, the biogenic methane. The current advanced analysis using Next-Generation Sequencing (NGS) of rumen microbiomes offered a more insightful understanding of their ability to degrade more fibrous feeds, especially agricultural crop residues, low-quality roughages, and some plastic materials. …”
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Mycobiome analyses of critically ill COVID-19 patients by Danielle Weaver, Sara Gago, Matteo Bassetti, Daniele Roberto Giacobbe, Juergen Prattes, Martin Hoenigl, Florian Reizine, Hélène Guegan, Jean-Pierre Gangneux, Michael John Bromley, Paul Bowyer

“…Our study provides insights into the lung fungal microbiome in severe COVID-19 and has found antifungal treatment to be associated with lower Aspergillus fumigatus burden and that higher levels of this pathogen are associated with mortality. …”
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AI versus human-generated multiple-choice questions for medical education: a cohort study in a high-stakes examination by Alex KK Law, Jerome So, Chun Tat Lui, Yu Fai Choi, Koon Ho Cheung, Kevin Kei-ching Hung, Colin Alexander Graham

“…AI questions primarily tested lower-order cognitive skills, while human MCQs better assessed higher-order skills (χ² = 14.27, p = 0.003). …”
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Assessment of Knowledge Gaps in Cervical Cancer Screening and HPV Vaccination Among Chinese Women: A Comprehensive Population-Based Study by Huang X, Ruan G, Sun P

“…Factors associated with lower CCS knowledge included low monthly household income, lack of rural cooperative medical insurance, low literacy, not having received CCS within the past 3 years, unmarried status, and childbirth history. …”
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Screening attendance of breast or cervical cancers and its associated factors among 30-49 year old women in Gedeo zone, South Ethiopia: Cross-sectional study. by Abel Desalegn Demeke, Bedilu Deribe, Martha Girma, Muluken Gizaw, Sefonias Getachew, Susanne Unverzagt, Eva J Kantelhardt, Betty Ferrell, Eric Sven Kroeber, Lesley Taylor

“…High response cost ([AOR] 0.19 95% CI [0.08, 0.50]) was a negative factor and associated with lower screening attendance.<h4>Conclusion and recommendation</h4>The study found that only one in four women attended breast or cervical cancer screening. …”
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Using microfluidic shear to assess transfusion requirements in trauma patients by Rachael A Callcut, James T Ross, Anamaria J Robles, Leslie H Vuoncino, Ashli C Barnes, Leonardo W Graeff, Taylor L Anway, Nico T Vincent, Nithya Tippireddy, Kimi M Tanaka, Randi J Mays

“…An elevated international normalized ratio significantly correlated with decreased cumulative PCF (p=0.05), maximum PCF (p=0.05) and CA (p=0.02). Lower cumulative PCF significantly correlated with transfusion of any products at 6 and 24 hours (p=0.04 and p=0.05) as well as packed red blood cells (pRBCs) at 6 and 24 hours (p=0.04 and p=0.03). …”
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Counting the cost of hospitalised injury using administrative data in Australia: three considerations from a retrospective cohort data linkage study by Jacelle Warren, Kirsten Vallmuur, Victoria McCreanor, Steven M McPhail, Shahera Banu, Michael Schuetz, Clifford Afoakwah

“…CPI-inflated costs were significantly lower than health group index-inflated estimates, with observed differences between 7.7% (95% CI 6.9% to 8.7%) and 11.9% (95% CI 10.8% to 13.1%) for the same AR-DRG. …”
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Improving the Biostability of Extra Virgin Olive Oil with Olive Fruit Extract During Prolonged Deep Frying by Taha Mehany, José M. González-Sáiz, Consuelo Pizarro

“…However, HTyr-EVOOs exhibited lower rancidity compared to non-enriched oils under identical conditions, attributed to the protective effect of HTyr. …”
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Efficacy and safety of ketamine and esketamine in reducing the incidence of postpartum depression: an updated systematic review and meta-analysis by Moaz Yasser Darwish, Abdallah A. Helal, Yousif Ahmed Othman, Manar Alaa Mabrouk, Aya Alrawi, Taha Abd-ElSalam Ashraf, Nada K. Abdelsattar, Fatma Mohammed Sayed, Mohamed Abd-ElGawad

“…Conclusion Both ketamine and esketamine are effective in lowering the incidence of short-term PPD. On the other hand, only esketamine is effective in reducing the incidence of long-term PPD. …”
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Evaluating metagenomics and targeted approaches for diagnosis and surveillance of viruses by Sarah Buddle, Leysa Forrest, Naomi Akinsuyi, Luz Marina Martin Bernal, Tony Brooks, Cristina Venturini, Charles Miller, Julianne R. Brown, Nathaniel Storey, Laura Atkinson, Timothy Best, Sunando Roy, Sian Goldsworthy, Sergi Castellano, Peter Simmonds, Heli Harvala, Tanya Golubchik, Rachel Williams, Judith Breuer, Sofia Morfopoulou, Oscar Enrique Torres Montaguth

“…While untargeted ONT had good sensitivity at high viral loads (60,000 gc/ml), at lower viral loads (600–6000 gc/ml), longer and more costly sequencing runs would be required to achieve sensitivities comparable to the untargeted Illumina protocol. …”
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Almajiri health; a scoping review on disease, health literacy and space for participatory research. by Muzzammil Imran Muhammad, Amna Hassana Abdulsalam, Fadhina Petit-Clair, Amber Acquaye, Autumn Nobles, Brian Fleischer, Chigoziri Konkwo, Yusuf Ransome, Elijah Paintsil

“…Studies comparing almajirai to controls found significantly higher rates of cholera, urinary schistosomiasis, and psychiatric disorders, lower levels of rabies awareness and poorer oral hygiene among almajirai (p<0.05). …”
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Thrombolysis, time-to-treatment and in-hospital outcomes among young adults with ischaemic stroke in China: findings from a nationwide registry study in China by Yong-Jun Wang, Xin Yang, Qi Zhou, Hao Li, Xia Meng, Yong Jiang, Li-Ping Liu, Yi-long Wang, Hong-Qiu Gu, Zi-Xiao Li, Xing-Quan Zhao, Chun-Juan Wang, Chelsea Liu, Hai-yan Wang, Ying-Yu Jiang

“…Compared with older adults, young adults treated with IV tPA had lower odds of in-hospital mortality (0.5% vs 1.3%, aOR 0.54, 95% CI 0.35 to 0.82) and higher odds of independent ambulation at discharge (61.0% vs 53.6%, aOR 1.15, 95% CI 1.08 to 1.22), and the associations may be partly explained by stroke severity measured by the National Institutes of Health Stroke Scale score.Conclusion Young adults with AIS were more likely to receive IV tPA than older adults, although there was no difference between the two groups in time to treatment. …”
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Identification of the crucial circ-mi-mRNA interaction networks regulating testicular development and spermatogenesis in ganders by Xiaopeng Li, Xiaoyong He, Guibi Li, Zhujun Wang, Fuli Huang, Jiasen Chen, Yang Song, Tanze Liu, Zhaoyan Chen, Xiangfeng Wang, Jiwei Hu, Hua He, Hehe Liu, Liang Li, Jiwen Wang, Shenqiang Hu

“…At the morphological level, the left, right, and bilateral testicular weights, the right and bilateral testicular organ indexes, and the long, short, and dorsoventral diameters of the left, right and bilateral testes were significantly lower in AG than in NG (P < 0.05). At the histological level, most testicular histological parameters, such as the testicular parenchymal area, the diameter of seminiferous tubules, and the number of germ cells, were significantly higher (P < 0.05) in NG than in AG. …”
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Use of Cesarean Birth among Robson Groups 2 and 4 at Mizan-Tepi University Hospital, Ethiopia by Margo S. Harrison, Tewodros Liyew, Ephrem Kirub, Biruk Teshome, Andrea Jimenez-Zambrano, Margaret Muldrow, Teklemariam Yarinbab

“…In multivariable modeling of Robson Group 4, having a labor longer than 24 hours trended towards a significant association with cesarean (RR 3.6, CI (0.9, 14.3)), and women had a more dilated cervix on admission trended toward having a lower odds of cesarean (RR 0.8, CI (0.6, 1.0)). Conclusion. …”
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Initial treatment with a single capsule containing half-dose quadruple therapy vs standard-dose dual therapy in hypertensive patients (QUADUAL): a randomized, blinded, crossover tr... by Xiexiong Zhao, Tao Liu, Qiong Yang, Guoping Yang, Xingli Li, Xiaohong Tang, Jingle Li, Zhongshu Liang, Anying Li, Lixiong Zeng, Juan Wen, Xiaoyan Wang, Liping Peng, Wenjuan Wang, Jingjing Cai, Ye Chen, Miao Huang, Ruixuan Li, Ru Fu, Lin Zhao, Xiaogang Li, Weihong Jiang

“…Conclusions Initiating treatment with half-dose quadruple combination therapy was more effective in lowering blood pressure than standard-dose dual therapy. …”
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Prevalence of anaemia and its associated factors among HIV-infected adults at the time of ART initiation at Debre Markos Comprehensive Specialized Hospital, Northwest Ethiopia: a r... by Agazhe Aemro, Belayneh Shetie Workneh, Enyew Getaneh Mekonen, Mulugeta Wassie, Basazinew Chekol

“…Hence, giving special attention to those who have not attended formal education, were males, had decreased baseline CD4+ T cell count, had lower BMI and patients with ambulatory/bedridden baseline functional status is crucial to reduce the health impact of anaemia. …”
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UPLC-MS/MS Method for Givinostat in Rat Plasma: Development, Validation, in vivo Pharmacokinetics Study and in vitro Metabolic Stability Research by Zhan R, Liu Y, Wu J, Shen Y, Xu X, Lin G, Chen X

“…The intra- and inter-day precisions (RSD%) were lower than 15%, with an accuracy (RE%) of 95.8%– 108.6%. …”
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Efficacy analysis of prophylactic hyperthermic intraperitoneal chemotherapy in patients with locally advanced gastric cancer: a retrospective study by Zhijie Gong, Zhijie Gong, Liping Zhou, Yinghao He, Yinghao He, Jun Zhou, Yanjie Deng, Zudong Huang, WeiWei Wang, Qiangbang Yang, Jian Pan, Yingze Li, Xiaolu Yuan, Minghui Ma

“…The incidence of isolated peritoneal metastasis (PM) was significantly lower in the HIPEC group (5.3% vs. 17.3%, p = 0.039). …”
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