Local and Systemic CD4+ T Cell Exhaustion Reverses with Clinical Resolution of Pulmonary Sarcoidosis by Charlene Hawkins, Guzel Shaginurova, D. Auriel Shelton, Jose D. Herazo-Maya, Kyra A. Oswald-Richter, Joseph E. Rotsinger, Anjuli Young, Lindsay J. Celada, Naftali Kaminski, Carla Sevin, Wonder P. Drake

“…PD-1 expression and apoptosis were assessed by flow cytometry. Compared to healthy controls, sarcoidosis CD4+ T cells demonstrated reductions in Th1 cytokine expression, proliferative capacity (p<0.05), enhanced apoptosis (p<0.01), and increased PD-1 expression (p<0.001). …”
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A 3D Approach for the Virtual Commissioning of Processing Plants by Nikolai Striffler, Tobias Voigt

“…The simulation model is designed to depict complex fluid and material flows within a 3D environment, facilitating realistic, real-time interaction and improved visualization for VC. …”
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miR-504 Promoted Gastric Cancer Cell Proliferation and Inhibited Cell Apoptosis by Targeting RBM4 by Yi Zhang, Hongmei Yong, Jing Fu, Guangyi Gao, Huichang Shi, Xueyi Zhou, Mingsheng Fu

“…Cell proliferation and cell apoptosis were assessed by colony formation assay and flow cytometry, respectively. Luciferase reporter gene assays were used to investigate interactions between miR-504 and RBM4 in SGC-7901 cells. …”
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Evolution Mechanism of Water-Conducting Channel of Collapse Column in Karst Mining Area of Southwest China by Zhengzheng Cao, Yulou Ren, Qinting Wang, Banghua Yao, Xinchao Zhang

“…The results show that the water flowing into the 1908 working face comes from the Changxing formation aquifer and Yulongshan formation aquifer above the coal seam, and the proportion of coarse particles and fine particles in collapse column is 89.86% and 10.14%, respectively. …”
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Synergistic Enzybiotic Effect of a Bacteriophage Endolysin and an Engineered Glucose Oxidase Against <i>Listeria</i> by David Talens-Perales, José-Antonio Daròs, Julio Polaina, Julia Marín-Navarro

“…The combination of the two enzybiotics resulted in a synergistic effect with a log reduction in viable cells (log N₀/N) of 4, whereas, taken separately, the same dose of A10 and GOX caused only 1.2 and 0.2 log reductions, respectively. Flow cytometry and microscopy analyses revealed that A10 treatment alone induced the aggregation of dead cells. …”
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Research on the Formation Characteristics of Fog and Frost on Optical Windows of Unsealed Equipment Compartments in Aircrafts by Chun Shen, Yuanyuan Liang, Bo Wei, Chengchun Zhang, Tian Zhao

“…In this study, a numerical method for the formation and dissipation of fog and frost is established using the Eulerian multiphase flow liquid film model. In this approach, the formation and dissipation of fogging and frosting layers is directly determined by the saturation of the water vapor surface, and it does not depend on any empirical coefficients. …”
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A CEO's internal communication programme for middle management and its influence on their perception of the corporate reputation by Irma Meyer, Gideon de Wet

“…A pragmatic research approach was adopted for this study, and two communication theories – the systems theory and in particular the interrelatedness aspect thereof, and the flow of information aspects of the information theory (Bowers & Courtright, 1984: 23) - were used as the conceptual premise of the study. …”
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Discussion on Optimization of Public Transportation Network Setting considering Three-State Reliability by Zhang Xiaoliang, Jia Limin

“…The traditional bus route design is mainly based on the “four-stage” method model, which is mainly based on the investigation and analysis of the existing traffic system and land use. Through the work flow of “evaluation, calibration, and verification,” the network balance optimization model is used to get the bus travel allocation prediction model. …”
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Comparison of Intranasal Outer Membrane Vesicles with Cholera Toxin and Injected MF59C.1 as Adjuvants for Malaria Transmission Blocking Antigens AnAPN1 and Pfs48/45 by Michael Pritsch, Najib Ben-Khaled, Michael Chaloupka, Sebastian Kobold, Nicole Berens-Riha, Annabell Peter, Gabriele Liegl, Sören Schubert, Michael Hoelscher, Thomas Löscher, Andreas Wieser

“…T cell responses (cytotoxic T cells, Th1, Th17, and regulatory T cells) were determined by flow cytometry. When OMV were used as adjuvant for intranasal immunization, antibody and cellular responses against all three antigens could be induced, comparable to cholera toxin and MF59C.1. …”
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Immune Activation, Immunosenescence, and Osteoprotegerin as Markers of Endothelial Dysfunction in Subclinical HIV-Associated Atherosclerosis by Alessandra D’Abramo, Maria Antonella Zingaropoli, Alessandra Oliva, Claudia D’Agostino, Samir Al Moghazi, Giulia De Luca, Marco Iannetta, Claudio Maria Mastroianni, Vincenzo Vullo

“…CD4+/CD8+ T-cell activation (CD38+ HLADR+) and senescence (CD57+ CD28−) were measured by flow cytometry. IL-6 and OPG levels were measured by ELISA kit. c-IMT was higher in HIV+ than in controls. …”
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Credit Risk Assessment for Small and Microsized Enterprises Using Kernel Feature Selection-Based Multiple Criteria Linear Optimization Classifier: Evidence from China by Yimeng Wang, Yunqi Zhang

“…The results show that (1) the proposed KFS-MCLOC has greater advantages in predictive accuracy, interpretability, and stability than other models; (2) the KFS-MCLOC selects 10 features from 53 original features and gives selected features their weight automatically; (3) the features selected by the KFS-MCLOC are further verified and compared by the features selected by the logistic regression model with stepwise parameter, and the indicators of “quick ratio; net operating cash flow; enterprises’ abnormal times of water, electricity, and tax fee; overdue days of enterprises’ loans; and mortgage and pledge status” are proved to be the most influencing credit risk factors.…”
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Fine-scale forest classification with multi-temporal sentinel-1/2 imagery using a temporal convolutional neural network by Rongfei Duan, Chunlin Huang, Peng Dou, Jinliang Hou, Ying Zhang, Juan Gu

“…A Temporal Convolutional Neural Network (TempCNN), which excels in handling temporal data and adapting to complex patterns, was constructed using TensorFlow with 133.8k parameters. The model was compared with CNN, random forest, XGBoost, and long short-term memory to validate its advantages. …”
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Endothelial Differentiation of Human Adipose-Derived Stem Cells on Polyglycolic Acid/Polylactic Acid Mesh by Meng Deng, Yunpeng Gu, Zhenjun Liu, Yue Qi, Gui E. Ma, Ning Kang

“…Cell adhesion, viability, and distribution of hADSCs on PGA/PLA mesh were observed by CM-Dil labeling, live/dead staining, and SEM examination while endothelial differentiation was evaluated by flow cytometry, Ac-LDL/UEA-1 uptake assay, immunofluorescence stainings, and gene expression analysis of endothelial related markers. …”
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Flash floods on the northern coast of the Black Sea: Formation and characteristics by Ludmila Kuksina, Pelagiya Belyakova, Valentin Golosov, Ekaterina Zhdanova, Maxim Ivanov, Anatoly Tsyplenkov, Artem Gurinov

“…The small watershed area (≤351 km2) of river basins experiencing flash floods promotes very rapid flow concentration. Analysis of extreme precipitation demonstrates significant increasing trends in river basins on the Crimean Peninsula and decreasing a maximum precipitation amount in 5 days (r5d) and 1 day (r1d) in river basins in the Caucasus Black Sea Coast in the 21st century as determined by processing of Integrated Multi-satellite Retrievals for Global precipitation measurement (IMEGR) satellite data. …”
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Differentiation-Associated MicroRNA Alterations in Mouse Heart-Derived Sca-1+CD31− and Sca-1+CD31+ Cells by Qiong Wu, Jinxi Zhan, Yun Li, Xiaoxia Wang, Lu Xu, Juan Yu, Shiming Pu, Zuping Zhou

“…The purposes of this study were to (1) isolate CSC/CPCs with Lin−CD45−Sca-1+CD31− and Lin−CD45−Sca-1+CD31+ surface antigens using flow-activated cell sorting; (2) investigate their differentiation potential; and (3) determine the molecular basis for differences in stemness characteristics between cell subtypes. …”
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Lifecycle Risk Assessment for Steel Cargo Vessel Sinkings: An Interpretive Structural Modeling and Fuzzy Bayesian Network Approach by Xiaodan Jiang, Haibin Xu, Yaming Zhu, Yingxia Gu, Shiyuan Zheng

“…Intermediate risk factors from deeper to surface layers flow from shipping companies to crew and further to vessel and environmental conditions. …”
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Transitions of deformation mechanisms in new metastable β-titanium Ti-1500G alloy by Yongqiang Ye, Yuanfei Han, Siyuan Zhang, Jianwen Le, Fu Chen, Jiaming Zhang, Chunyu Shen, Guangfa Huang, Shewei Xin, Weijie Lu, Di Zhang

“…An integrated response of the flow stress caused by multiple mechanisms initiated softening and work hardening was characterized using a strain-compensated constitutive model, including shear bands, dynamic recovery and dynamic recrystallization (DRX). …”
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Dynamic characteristic analysis and load design of large floating structures based on experimental design by Guofeng Zhao, Shifan Zhu

“…The boundary element method based on potential flow theory is applied to calculate the frequency domain response of the structure, and the time domain response of the structure is calculated by the Fourier transform and convolution method. …”
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Combined Application of Coagulation/Flocculation/Sedimentation and Membrane Separation for the Treatment of Laundry Wastewater by Camila O. C. Nascimento, Márcia T. Veit, Soraya M. Palácio, Gilberto C. Gonçalves, Márcia R. Fagundes-Klen

“…The maximum values of color, total nitrogen, dissolved solids, and turbidity removal were similar to MF and UF membranes at transmembrane pressure of 1.4 bar, with the greatest flow of permeates (92.2 L·h−1·m−2) presented by the MF membrane at 1.4 bar. …”
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Design and Application of a Financial Distress Early Warning Model Based on Data Reasoning and Pattern Recognition by Xiaoya Hu

“…Difference nonparametric test and Spearman nonparametric correlation analysis were carried out with cash flow financial data, and 14 financial indicators with strong discriminant ability were selected from 28 financial indicators as the input variables of the model. …”
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