Development and validation of the Michigan Chronic Disease Simulation Model (MICROSIM). by James F Burke, Luciana L Copeland, Jeremy B Sussman, Rodney A Hayward, Alden L Gross, Emily M Briceño, Rachael Whitney, Bruno J Giordani, Mitchell S V Elkind, Jennifer J Manly, Rebecca F Gottesman, Darrell J Gaskin, Stephen Sidney, Kristine Yaffe, Ralph L Sacco, Susan R Heckbert, Timothy M Hughes, Andrzej T Galecki, Deborah A Levine

“…This manuscript describes the design principles, implementation details, and population-level validation of a novel population-health microsimulation framework, the MIchigan ChROnic Disease SIMulation (MICROSIM), for The Effect of Lower Blood Pressure over the Life Course on Late-life Cognition in Blacks, Hispanics, and Whites (BP-COG) study of the effect of BP levels over the life course on dementia and cardiovascular disease. …”
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A scoping review and prevalence analysis of soil-transmitted helminth infections in Honduras. by Ana Lourdes Sanchez, José Antonio Gabrie, María Mercedes Rueda, Rosa Elena Mejia, Maria Elena Bottazzi, Maritza Canales

“…Prevalences above 20% for each trichuriasis, ascariasis, and hookworm infection were found in 68%, 47.8%, and 7.2% of studied municipalities, respectively. Municipalities with lower human development index, less access to of potable water, and with higher annual precipitation showed higher STH prevalences.…”
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Caspase-1 activation, IL-1/IL-6 signature and IFNγ-induced chemokines in lungs of COVID-19 patients by Audrey Cambon, Christophe Guervilly, Christophe Guervilly, Clémence Delteil, Nicola Potere, Richard Bachelier, Edwige Tellier, Evelyne Abdili, Evelyne Abdili, Marine Leprince, Marco Giani, Ildo Polidoro, Valentina Albanese, Paolo Ferrante, Laurence Coffin, Michael Schiffrin, Laurent Arnaud, Romaric Lacroix, Romaric Lacroix, Sandrine Roque, Jean-Marie Forel, Jean-Marie Forel, Sami Hraiech, Sami Hraiech, Laurent Daniel, Laurent Papazian, Françoise Dignat-George, Françoise Dignat-George, Gilles Kaplanski, Gilles Kaplanski

“…Soluble Caspase-1p20, IL-1β, IL-1Ra, IL-6 and at lower level IFNγ and CXCL-10, were highly elevated in BALF from steroid-treated-C-ARDS as well as in NC-ARDS. …”
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Abnormal Esophageal Scintigraphy Associates With a Distinct Clinical Phenotype in Patients With Systemic Sclerosis by Antonio D. Salas, Lisa R. Yanek, Laura K. Hummers, Ami A. Shah, Zsuzsanna H. McMahan

“…Patients with delayed esophageal transit were more likely to have diffuse SSc (24 [32%] vs 11 [22%]; P = 0.024), severe lung involvement (22 [41%] vs 7 [19%]; P = 0.034), severe Raynaud (36 [47%] vs 15 [31%]; P = 0.063), and a higher median (interquartile range [IQR]) diarrhea GIT score (0.5 [IQR 0–1] vs 0 [IQR 0–1]; P = 0.050). Lower diffusing capacity of the lungs for carbon monoxide values correlated with a higher esophageal transit time (ρ = −0.32; P = 0.014). …”
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The effects of the urotensin-II receptor antagonist palosuran treatment on the corpora cavernosa of streptozotocin-induced diabetic rats by Murat Olukman, Cenk Can, Sibel Ülker, Yiğit Uyanikgil, Türker Çavuşoğlu, Neslihan Düzenli, Deniz Coşkunsever, Fatma G. Kozcu

“…The expression level of nNOS was lowered in diabetic CC; however, palosuran treatment did not change the decreased the neuronal NOS expression. …”
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GsMTx-4 combined with exercise improves skeletal muscle structure and motor function in rats with spinal cord injury. by Xin Zhang, Xinyu Liu, Qianxi Li, Chenyu Li, Xinyan Li, Jinghua Qian, Jianjun Li, Xuemei Li

“…This study was conducted on animal models, it offers insights for SCI treatment, advancing understanding of lower limb muscle pathology post-SCI. Further research is needed for clinical validation in the future.…”
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Structural features of correlations in lines with the naturally colored fiber in the trait-specific collection by L. P. Podolnaya, R. K. Tuz, M. Sh. Asfandiiarova, T. P. Rybakova, N. A. Khodjaeva

“…The negative correlation of fiber color with the first generative branch height (r = -0.53), and positive with the fiber yield (r = 0.57) indicate that the lines with brown fiber have a lower height of fruiting branches development (and potentially a shorter growing season) and a larger yield of fiber. …”
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Calibration of Low-cost Sensors for Measurement of Indoor Particulate Matter Concentrations via Laboratory/Field Evaluation by Doheon Kim, Dongmin Shin, Jungho Hwang

“…Each LCS indicated higher mass concentrations than GRIMM 11-D for small-sized PSL particles (0.56 µm); however, the LCSs indicated lower mass concentrations than GRIMM 11-D for PSL particles larger than 0.56 µm. …”
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Finite element analysis of stress in mandibular molars repaired after fractured instrument removal by Salih Düzgün, Emir Esim, Tuğrul Aslan, Ayşe Tuğba Eminsoy Avcı

“…Conclusions Biodentine (Septodont) may be preferable to MTA for filling staging platform cavities post-fractured instrument removal due to lower stress levels. Furthermore, calcium silicate-based materials alone or in combination with Gutta-percha showed similar stress levels, suggesting their potential use for root canal filling. …”
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Burden of Antimicrobial Resistance in Adult Hospitalized Patients With Cancer: A Multicenter Analysis by Vikas Gupta, Michael J. Satlin, Kalvin Yu, Yehoda M. Martei, Lillian Sung, Lars F. Westblade, Scott C. Howard, ChinEn Ai, Diane C. Flayhart

“…The percentage of nonsusceptible isolates in most pathogen groups was lower in patients with versus without cancer except for ESBL producers among Enterobacterales (odds ratio (OR), 1.11 [95% CI, 1.07, 1.15]) and vancomycin resistance among enterococci (OR, 1.22 [95% CI, 1.14, 1.30]), which were higher in cancer patients. …”
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Effects of kelp phlorotannins on the growth, immunity, intestinal health and disease resistance against Vibrio splendidus of sea cucumber Apostichopus japonicus by Zhikai Zhang, Yan Chi, Yongheng Du, Feng Li, Ning Ma, Song Qin

“…And 0.8 g kg−1 of phlorotannins induced the lowest post-challenge motility, which was about 43 % lower than control group. On one hand, dietary phlorotannins significantly increased total coelomocytes counts, phagocytosis, superoxide anion production (P < 0.05). …”
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Relative abrasive potential of silica-based conventional and tablet dentifrices on enamel and dentin. by Shaira R Kasi, Rafaela Oliveira Pilecco, Lucas Saldanha da Rosa, João Paulo Mendes Tribst, Cornelis Johannes Kleverlaan, Mutlu Özcan, Albert J Feilzer

“…Prodent also induced the highest enamel wear (2.64 μm) among the toothpaste formulations, while water, Zendium, and Denttabs exhibited comparatively lower enamel wear values. Statistical analysis using One-way ANOVA with two-sided Dunnett's multiple comparisons against the control (water) confirmed these differences.…”
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Karyopherin Alpha 2-Expressing Pancreatic Duct Glands and Intra-Islet Ducts in Aged Diabetic C414A-Mutant-CRY1 Transgenic Mice by Satoshi Okano, Akira Yasui, Shin-ichiro Kanno, Kennichi Satoh, Masahiko Igarashi, Osamu Nakajima

“…In mature stages, the level of KPNA2 expression was lower in islets of Tg mice than in wild-type controls. …”
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Effects of Escherichia coli Nissle 1917 on immunity, blood constituents, antioxidant capacity, egg quality and performance in laying Japanese quail by Asghar Sedaghat, Mohammad Amir Karimi Torshizi, Mohammad Reza Soleimani

“…Likewise, these groups demonstrated heavier egg weight (EW) and lower MDA in the meat sample. The MDA concentration of fresh yolk samples in groups receiving EcN was higher but diminished after iron-inducing (P < 0.05). …”
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Preparation and Photocatalytic Characterization of Modified Nano TiO2/Nd/Rice Husk Ash Material for Rifampicin Removal in Aqueous Solution by Thuy Dang Thi Ngoc, Ha Nguyen Thi, Dung Nguyen Duc, Sen Nguyen Thi, Toan Nguyen Duc, Nam Nguyen Hoang

“…The rifampicin-degrading efficiency of TiO2/Nd and TiO2/Nd/rice husk ash material reached approximately 86 and 75%, respectively, within 90 min under sunlight. Although a lower efficiency was obtained, the TiO2/Nd/rice husk ash material was selected to degrade rifampicin residue in water via the photocatalytic process (under sunlight) because of its advantages such as requirement of a small amount and easy recovery. …”
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Effects of the Stanford Chronic Conditions Model on Behavioral and Clinical Indicators in Saudi Arabia: A Prospective Quasi-Experimental Study by Bahari G, Kerari A, Alsadoun A, Alnassar M

“…Data analysis included analysis of descriptive and covariance statistics.Results: The analysis of covariance indicated that individuals who received the Chronic Disease Self-Management Program had significantly lower systolic (F=5.60, p< 0.05) and diastolic blood pressure (F=7.60, p< 0.01). …”
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A Mitochondria‐Related Signature in Diffuse Large B‐Cell Lymphoma: Prognosis, Immune and Therapeutic Features by Zhen‐Zhong Zhou, Jia‐Chen Lu, Song‐Bin Guo, Xiao‐Peng Tian, Hai‐Long Li, Hui Zhou, Wei‐Juan Huang

“…The high‐risk group had shorter overall survival, less immune infiltration, lower CD20 and higher PD‐L1 expression than the low‐risk group. …”
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Growth and Performance of Baby Spinach (Spinacia oleracea L.) Grown under Different Organic Fertilizers by C. Parwada, V. Chigiya, W. Ngezimana, J. Chipomho

“…Low quality (large C/N) cattle and goat manure had lower effects than high quality (small C/N) poultry manure at early growth stages of the baby spinach. …”
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The Impact of Socioeconomic Inequalities on the Risk of Hypertension in Bangladesh: A Systematic Review and Meta‐Analysis by Kabir Hossain, Tonmoy Alam Shuvo, Asma‐Ul Hosna, Dipu Rani Dey

“…Working individuals had a 39% lower risk of hypertension (OR = 0.61, 95% CI: 0.43–0.80) compared to nonworking individuals.…”
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MicroPulse Transscleral Laser Therapy Demonstrates Similar Efficacy with a Superior and More Favorable Safety Profile Compared to Continuous-Wave Transscleral Cyclophotocoagulation by Enrico Bernardi, Marc Töteberg-Harms

“…MP-TLT was as effective in lowering IOP as CW-TSCPC and achieved comparable success. …”
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