Immunosuppressive treatment results in patients with primary IgA nephropathy in Turkiye; the data from TSN-GOLD working group by Aysegul Oruc, Abdullah Sumnu, Aydın Turkmen, Taner Basturk, Egemen Cebeci, Kenan Turgutalp, Hakkı Cetinkaya, Müge Uzerk Kibar, Nurhan Seyahi, Erhan Tatar, Metin Ergul, Ülver Derici, Mehmet Deniz Aylı, Musa Pınar, Betül Bakar, Rümeyza Kazancıoglu, Abdülmecit Yıldız, Ahmet Burak Dirim, Zülfükar Yılmaz, Kültigin Turkmen, Onur Tunca, Mehmet Koc, Sim Kutlay, Hasan Micozkadıoglu, Alper Azak, Burcu Boztepe, Sedat Ustundag, Seda Şafak Ozturk, Abdulkadir Unsal, Serhat Karadag, Gülizar Sahin, Ezgi Coşgun Yenigun, Necmi Eren, Mustafa Gullulu, Meltem Gursu, Savaş Ozturk

“…Baseline systolic blood pressure, mean arterial pressure, and proteinuria levels were lower in responsives. Remission was achieved at significantly higher rates in the CS group (78% vs. 66.7%, p = 0.016). …”
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Associations between adverse childhood experiences and trust in health and other information from public services, professionals and wider sources: national cross sectional survey by Mark A Bellis, Karen Hughes, Kat Ford, Catherine Sharp, Rebecca Hill

“…However, a history of ACEs was associated with lower trust in supporting institutions, systems and professionals. …”
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The efficacy and safety of fluvoxamine in patients with COVID-19: A systematic review and meta-analysis from randomized controlled trials. by Qiufeng Zhou, Guozheng Zhao, Yu Pan, Ying Zhang, Yuehua Ni

“…Compared to the placebo group, the fluvoxamine group had a significantly lower rate of clinical deterioration (RR, 0.73; P = 0.004; 95% CI, 0.59 to 0.90; I2 = 0%) and hospitalization (RR, 0.76; P = 0.04; 95% CI, 0.59 to 0.99; I2 = 0%). …”
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ABCD3-I and ABCD2 Scores in a TIA Population with Low Stroke Risk by Fredrik Ildstad, Hanne Ellekjær, Torgeir Wethal, Stian Lydersen, Hild Fjærtoft, Bent Indredavik

“…Since there is a generally lower stroke risk after TIA during the last years, the benefit of these clinical risk scores and their role in TIA management seems limited. …”
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Visual and somatosensory evoked potentials abnormalities among Behçet’s disease patients and their relation to disease activity, severity and antiphospholipid antibodies: a cross-s... by Ghada S. Nageeb, Enass A. Eliwa, Ibrahim Tharwat, Lamiaa A. Mohammad, Nada Alaa Attia

“…Prolonged Central conduction time of upper limb and lower limb evaluated by N13- N20 IPL and N22-P39 IPL respectively may be used to detect nervous system involvement in BD patients. …”
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Urinary Tract Infections in Children: Changing Trends in Etiology and Local Resistance Patterns over a Three-Year Period by Patrícia Sousa, Lucinda Delgado, Susana Correia-de-Oliveira, Cecília Pereira, Ângela Dias, Ana Cláudia Tavares

“…The switch from A-C to cefuroxime as first-line agent resulted in a decreasing trend in A-C resistance, while cefuroxime resistance remained low and even slightly lower. …”
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Impaired Glucose Metabolisms of Patients with Obstructive Sleep Apnea and Type 2 Diabetes by Ye Zhang, Yanpeng Xing, Haibo Yuan, Xiaokun Gang, Weiying Guo, Zhuo Li, Guixia Wang

“…As for OSA patients with T2DM, the severe OSA group had higher homeostasis model assessment of insulin resistance (HOMA-IR) (P=0.013) than the mild-to-moderate OSA group, whereas had lower morning plasma cortisol levels (P=0.005) than the mild-to-moderate OSA group. …”
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In silico study of Sambiloto (Andrographis paniculata) compounds from GC-MS and LC-MS/MS as alpha-glucosidase and DPP-4 enzyme inhibitor by Herni Kusriani, Purwaniati Purwaniati, Muhamad Ilham Bintang

“…Sambiloto showed activity in lowering blood glucose which has the potential as an antidiabetic. …”
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Evaluation of the practical application of the category-imbalanced myeloid cell classification model. by Zhigang Hu, Aoru Ge, Xinzheng Wang, Cuisi Ou, Shen Wang, Junwen Wang

“…However, the lightweight model RegNetX-3.2gf had significantly fewer parameters and a significantly faster inference speed than Swin Transformer V2, and its F1 Score was only 0.032 lower than that of Swin Transformer V2. Accordingly, RegNetX-3.2gf is strongly recommended for practical applications. …”
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Phantom motor execution as a treatment for phantom limb pain: protocol of an international, double-blind, randomised controlled clinical trial by Brian E McGuire, Lina Bunketorp-Käll, Eva Lendaro, Liselotte Hermansson, Helena Burger, Corry K Van der Sluis, Monika Pilch, Katarzyna Kulbacka-Ortiz, Ingrid Rignér, Anita Stockselius, Lena Gudmundson, Cathrine Widehammar, Wendy Hill, Sybille Geers, Max Ortiz-Catalan

“…Here we present the study protocol for an international (seven countries), multicentre (nine clinics), double-blind, randomised controlled clinical trial to assess the effectiveness of PME in alleviating PLP.Methods and analysis Sixty-seven subjects suffering from PLP in upper or lower limbs are randomly assigned to PME or phantom motor imagery (PMI) interventions. …”
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Profiling Serum Cytokines and Anticytokine Antibodies in Psoriasis Patients by Dan Hong, Xiuting Liu, Xiaonan Qiu, Siyao Lu, Yanyun Jiang, Guozhen Tan, Zhenrui Shi, Liangchun Wang

“…Of 13 anticytokine antibodies, anti-IL-22 was moderately lower (median: 262.8 vs.190.5, p=0.0418), and anti-IL-15 was slightly higher (median: 25.5 vs. 30.5, p=0.0069) in psoriasis than controls. …”
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Early- and Late-Onset Preeclampsia: A Comprehensive Cohort Study of Laboratory and Clinical Findings according to the New ISHHP Criteria by Anna Wójtowicz, Małgorzata Zembala-Szczerba, Dorota Babczyk, Monika Kołodziejczyk-Pietruszka, Olga Lewaczyńska, Hubert Huras

“…Children born to women with EOP had lower Apgar scores (p<0.001) and higher rates of intraventricular hemorrhage (p<0.0001), respiratory disorders requiring mechanical ventilation (p<0.0001), and early (p=0.0004) and late sepsis (p=0.002). …”
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Osteoperiosteal versus osteochondral for autologous transplantation in the treatment of large cystic osteochondral lesions of the talus by Lequan Liu, Jiangtao Jin, Jinping Pan, Huikang Guo, Sen Li, Jisheng Li, Zheng Zhang

“…Conclusions In the treatment of large cystic OLTs, for patients with a chondral lesion of the patellofemoral joint that is unsuitable for AOCT, AOPT may be a safe and effective choice, with lower donor-site morbidity of the normal knee joint.…”
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Interference of Celastrol with Cell Wall Synthesis and Biofilm Formation in <i>Staphylococcus epidermidis</i> by Leandro de León Guerra, Nayely Padilla Montaño, Laila Moujir

“…Time–kill assays revealed a concentration-dependent bactericidal effect, with a shift from bacteriostatic activity at lower concentrations to bactericidal and lytic effect at higher concentrations. …”
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Physical and occupational therapy service delivery models for populations identified as hard-to-reach: A scoping review. by Kenneth S Noguchi, Muhib Masrur, Lori Letts, Susanne Sinclair, Sarah Wojkowski, Julie Richardson

“…<h4>Results</h4>Twenty-one articles with variable sample sizes (min, max n = 3 to 237) were included and detailed PT and/or OT services for immigrants/migrants, refugees, hard-to-reach veterans, people experiencing homelessness, lower incomes, trauma/torture, and those living in rehabilitation-deficient areas. …”
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Evaluating the impact of donor eGFR and HLA-DR mismatch on graft survival in living donor kidney transplants by Pooja Budhiraja, Jesse D. Schold, Jesse D. Schold, Rocio Lopez, Rocio Lopez, Susana Arrigain, Susana Arrigain, Bruce Kaplan, Bruce Kaplan

“…Similar results were observed for patient survival.ConclusionsHigher donor eGFR was associated with lower risks of graft loss and patient death in the HLA-DR mismatch group but not the 0 HLA-DR mismatch group. …”
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The use of methylene blue in adult patients with septic shock: a systematic review and meta-analysis by Ka Ting Ng, Pei En Kwok, Wei En Lim, Wan Yi Teoh, Mohd Shahnaz Hasan, Mohd Fitry Zainal Abidin

“…Patients who were given methylene blue were associated with statistically lower mortality rate (OR = 0.49, 95% CI 0.27 to 0.88, p = 0.02, level of evidence: low), reduced serum lactate levels (MD: -0.76 mmoL.L-1, 95% CI -1.22 to -0.31, p = 0.0009, level of evidence: low), reduced length of hospital stay (MD: -1.94 days, 95% CI -3.79 to -0.08, p = 0.04, level of evidence: low), and increased PaO2/FiO2 (MD: 34.78, 95% CI 8.94 to 60.61, p = 0.008, level of evidence: low). …”
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Functional Connectivity Changes in Multiple-Frequency Bands in Acute Basal Ganglia Ischemic Stroke Patients: A Machine Learning Approach by Jie Li, Lulu Cheng, Shijian Chen, Jian Zhang, Dongqiang Liu, Zhijian Liang, Huayun Li

“…In the contralesional M1, the BGIS patients showed lower FC with the right SFGmed in the conventional frequency band. …”
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Melatonin attenuates MPP+-induced autophagy via heat shock protein in the Parkinson’s disease mouse model by Yinli Guo, Chengbo Liu

“…The expression levels of HSP70 and CDK5 were significantly lower, while the expression levels of LC3 II /LC3I and p62 increased significantly. …”
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Can Thinning Foster Forest Genetic Adaptation to Drought? A Demo‐Genetic Modelling Approach With Disturbance Regimes by Victor Fririon, Hendrik Davi, Sylvie Oddou‐Muratorio, Gauthier Ligot, François Lefèvre

“…However, the conventional thinning practice of retaining the larger trees resulted in indirect anthropogenic selection that enhanced genetic gain in vigour and lowered sensitivity by up to 30%. More intensive thinning aimed at reducing drought stress by reducing stand density hampered the selection against sensitivity to drought, potentially hindering long‐term adaptation. …”
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