Clinical effect analysis of Hufu Tongbian scraping combined with Traditional Chinese medicine iontophoresis for patients with Fontaine's stage II arteriosclerosis obliteration (虎符铜... by (武亚楠), YE lei (叶蕾), HOU Jianan (侯佳楠), SU Kun (苏坤), YU Bo (于波), BAI Jianying (白建英), LI Liang (李亮)

“…After intervention, the scores of each dimension of symptom score and pain score in group D were lower than those in groups B and C (P＜0. 05), but there was no significant difference between groups B and C after intervention (P＞0. 05). …”
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Effect of Tiaoxin Recipe on Memory Learning and Synaptic Plasticity in APP/PS1 Double Transgenic Alzheimer's Disease Mice based on αCaMKⅡ-CREB-BDNF Signal Pathway by Xiaowen WANG, Hong QIAN, Chunjuan SHEN, Yanjun LI, Haixin YUAN, Jian WANG

“…During the 50-60 min stable period, compared with the model group, the slope of fEPSP in the LTP induced by Tiaoxin recipe group was significantly higher than that in the model group (<italic>P</italic>&lt;0.05).②RT-qPCR results: compared with the normal group, the expressions of αCaMKⅡ, CREB, BDNF and PSD-95mRNA in the hippocampus of the model group were significantly lower, and the difference was statistically significant (<italic>P</italic>&lt;0.05). …”
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Perbandingan Insidensi Hipotensi Saat Induksi Intravena Propofol 2 Mg/Kg Bb Pada Posisi Supine dengan Perlakuan dan Tanpa Perlakuan Elevasi Tungkai by Beni Indra, Untung Widodo, Yunita Widyastuti

“…In the third minute, incidence of hypotension was also significantly lower in group A (15,2%) than group B (23,9%), p value = 0,014 (p &lt; 0,05). …”
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Lake pulses driven by glacier melting and climate variability by Songtao Ai, Shoukat Ali Shah, Yi Cai, Jiajun Ling, Xinde Chu, Shijin Wang, Yuande Yang, Runchuan Ouyang, Jiachun An, Wolfgang Rack

“…Conversely, water level peaks occur approximately every 6.5 h, with a strong positive trend R2 = 0.99, indicating a slower recurrence rate. The transit time for meltwater from Baishui River Glacier No. 1 to BMLV is estimated at approximately 4.16 h. …”
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Determining the relationship between the speed of motion of large permanent magnets and the trajectory of implants in magnetic stereotaxic systems by Ц. Ханькунь, О. Г. Аврунін

“…The faster the large permanent magnet moves, the shorter the distance that the small permanent magnet moves along the linear trajectory, and the longer the distance that moves along the arc trajectory; The slower the large permanent magnet moves, the longer the small permanent magnet travels along a straight trajectory and the shorter the distance it travels along an arc trajectory. …”
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NPRL2 gene therapy induces effective antitumor immunity in KRAS/STK11 mutant anti-PD1 resistant metastatic non-small cell lung cancer (NSCLC) in a humanized mouse model by Ismail M Meraz, Mourad Majidi, Renduo Song, Feng Meng, Lihui Gao, Qi Wang, Jing Wang, Elizabeth J Shpall, Jack A Roth

“…Restoration of NPRL2 exhibited significantly slower tumor growth in humanized-mice, which was associated with increased presence of human cytotoxic-T, and DC and decreased percentage of Treg, MDSC, and TAM in TME. …”
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A conserved element in the first intron of Cd4 has a lineage specific, TCR signal-responsive, canonical enhancer function that matches the timing of cell surface CD4 upregulation r... by Gregory A. Swan, Gregory A. Swan, Chika Fujii, Mia E. Guzynski, Sheridan M. Page, Isabelle V. Meyers, Yordan P. Penev, Sejiro Littleton, Sejiro Littleton, Adinda Azzahra, Christine Richardson, Sophia D. Sarafova, Sophia D. Sarafova

“…Furthermore, CRISPR/Cas9-mediated deletion of coreNCE/E4m resulted in reduced CD4 surface levels, slower re-expression rates, and reduced TCR signaling responsiveness in INT cells, but not in DP cells. …”
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Risk Factors for Stress Fractures in Female Runners: Results of a Survey by Therese E Johnston, Allison E Jakavick, Caroline A Mancuso, Kathleen C McGee, Lily Wei, Morgan L Wright, Jeremy Close, Ayako Shimada, Benjamin E Leiby

“…Women running 11:00-11:59 minutes/mile or slower were less likely to have a stress fracture compared to those running 9:00-9:59 minutes/mile (OR 0.43-0.54). …”
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Study on Mechanical Performance of Prestressed UHPFRC U-Beam Bridges by Mengying Liu, Eugen Brühwiler, Fengkun Cui, Yue Xu

“…The farther away from the center the measurement point is, the slower its strain changes. Therefore, the load is mainly caused by the central rib and the loading center plate. …”
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Hameaux et villages paysans de la période romaine en plaine d’Alsace by Antonin Nüsslein, Pascal Flotté, Mathias Higelin, Muriel Roth-Zehner

“…The examples of rural settlements presented here are almost all located west of Strasbourg, in the area of the lower Bruche valley and in the Kochersberg area. …”
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The Impact of the Coexpression of MET and ESR Genes on Prognosticators and Clinical Outcomes of Breast Cancer: An Analysis for the METABRIC Dataset by Nehad M. Ayoub, Ghaith M. Al-Taani, Amer E. Alkhalifa, Dalia R. Ibrahim, Aymen Shatnawi

“…Patients with high MET/ESR1 coexpression had favorable clinicopathologic tumor characteristics and prognosticators compared to low MET/ESR1 coexpression in terms of greater age at diagnosis, reduced Nottingham Prognostic Index, lower tumor grade, hormone receptor positivity, HER2-negative status, and luminal subtype p<0.001. …”
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Turkish suicide patterns: Longitudinal analysis of suicide trends in Turkiye (2000 -2022) by Ayhan Tabur, Feruza Turan Sonmez

“…While the overall rate among individuals aged 65 and older was lower (2.9/100,000), a significant increase was noted in recent years, peaking at 4.2/100,000 in 2019. …”
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Preliminary investigation on the establishment of a new meibomian gland obstruction model and gene expression by Ming Sun, Huanmin Cheng, Zheng Yang, Jiangqin Tang, Shengshu Sun, Zhanglin Liu, Shaozhen Zhao, Lijie Dong, Yue Huang

“…Consequently, meibomian gland obstruction model rats were established successfully with corneal damage and lower tear film stability. Meibomian gland obstruction is a causative factor of MGD, which led to abnormal histological structure in MG, differential expression of PPAR signaling pathway and TRPV3.…”
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The Predictive Role of Lactate in the Emergency Department in Patients with Severe Dyspnea by Maciej Niczewski, Szymon Gawęda, Paulina Kluszczyk, Mikołaj Rycerski, Daria Syguła, Anna Danel, Szymon Szmigiel, Konrad Mendrala, Aleksandra Oraczewska, Czarosław Kijonka, Monika Nowicka, Michał Wita, Tomasz Cyzowski, Grzegorz Brożek, Maciej Dyrbuś, Szymon Skoczyński

“…Patients who died were more frequently initially assigned to the red triage risk group, more burdened with comorbidities, and the median SpO2 on admission was significantly lower than in patients who survived the follow-up period. …”
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Transcriptome analysis of ovarian cancer uncovers association between tumor-related inflammation/immunity and patient outcome by Jingfang Wang, Wenrui Zhu, Xia Li, Yuanyuan Wu, Wenhui Ma, Yangzhou Wang, Weihong Zhao, Fang Wei, Wenhao Wang

“…Further analysis revealed that the high-risk group had a higher abundance of M2-type macrophage infiltration, more active anti-tumor immune response, higher tumor stemness score, potentially worse prognosis, and lower response rates to multiple chemotherapy drugs and immune checkpoint inhibitors.ConclusionThese findings provide new perspectives and potential targets for immunotherapy and prognostic evaluation of ovarian cancer and offer new strategies and directions for clinical treatment and patient management. …”
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Seaweed Fly Larvae Cultivated on Macroalgae Side Streams: A Novel Marine Protein and Omega-3 Source for Rainbow Trout by Niklas Warwas, Emma L. Berdan, Xintian Xie, Elisabeth Jönsson, Jonathan A. C. Roques, Darragh Doyle, Markus Langeland, James Hinchcliffe, Henrik Pavia, Kristina Sundell

“…The feed conversion ratio of fish fed the BSFL and SWFL diets was higher compared to the control, suggesting lower bioavailability of both insect meals compared to fish meals. …”
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Pelletization of composted swine manure solid fraction with different organic co-formulates: effect of pellet physical properties on rotating spreader distribution patterns by Elio Romano, Massimo Brambilla, Carlo Bisaglia, Niccolò Pampuro, Ester Foppa Pedretti, Eugenio Cavallo

“…Introduction In Europe, because of the high production levels of livestock farming in general and pig farming in particular, animal waste management has become increasingly important to comply with the required lowering of livestock farming environmental pressure. …”
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Response Analysis of a Ballasted Rail Track Constructed on Soft Soil by 3D Modeling by Iram Lamiya Hoque, Shamontee Aziz, Joya Rani Mallick, Md. Arifuzzaman Nayeem, Tamanna-E-Hafiz Maisha, F. M. Zahid Hossain, A. F. M. S. Amin

“…Moreover, a high subballast stiffness can counterbalance the potential of forming permanent deformation by generating lower strains. However, a stiffer subballast does not play a prominent role in reducing the displacement of ballast or vertical stresses. …”
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Severe primary graft failure: Are there lasting impacts? Analysis from the PHTS Database by Jennifer Conway, MD, Tara Pidborochynski, MSc, James K. Kirklin, MD, Ryan Cantor, PhD, Hong Zhao, PhD, Aryaz Sheybani, MD, Jacqueline Lamour, MD, Lakshmi Gokanapudy Hahn, MD, Leslie Collins, MD, Jessica Laks, MD, Darren H. Freed, MD, PhD

“…Patients with PGF were younger, with higher proportion of congenital heart disease, longer cardiopulmonary bypass and ischemic times (IT), and more likely to be on extracorporeal membrane oxygenation or ventilator at HTx (all p < 0.0001, IT p = 0.0006). PGF resulted in lower overall survival (1 year: 54% vs 94%, p < 0.001). …”
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Circulating MMP-12 as Potential Biomarker in Evaluating Disease Severity and Efficacy of Sublingual Immunotherapy in Allergic Rhinitis by Yandan Zhou, Min Xu, Wei Gong, Xiaoming Kang, Renzhong Guo, Jie Wen, Dinggang Zhou, Manjing Wang, Dazhi Shi, Qiancheng Jing

“…Serum MRGPRX2 and MMP-12 levels were lower in the effective group than the ineffective group. …”
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