Prognostic value of body adipose tissue parameters in cancer patients treated with immune checkpoint inhibitors by Yan Li, Yean Yu, Kun Lv, Rongjuan Ge, Xie Xie

“…The analysis revealed that patients with higher levels of visceral adipose tissue (VAT) exhibited significantly improved OS (HR: 0.72, 95% CI: 0.59–0.89, p < 0.001) and PFS (HR: 0.80, 95% CI: 0.67–0.96, p = 0.015), along with a higher DCR (OR: 1.81, 95% CI: 1.26–2.60, p = 0.001), compared to those with lower VAT levels. Additionally, increased subcutaneous adipose tissue (SAT) levels were associated with significantly better OS (HR: 0.69, 95% CI: 0.58–0.82, p < 0.001) and PFS (HR: 0.82, 95% CI: 0.68–1.00, p = 0.049), and a higher DCR (OR: 1.99, 95% CI: 1.15–3.44, p = 0.014). …”
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Renin–angiotensin–aldosterone system activation in plasma as marker for prognosis in critically ill patients with COVID-19: a prospective exploratory study by Katharina Krenn, Felix Kraft, Luana Mandroiu, Verena Tretter, Roman Reindl-Schwaighofer, Theresa Clement, Oliver Domenig, Matthias G. Vossen, Gregor Riemann, Marko Poglitsch, Roman Ullrich

“…ICU patients showed higher concentrations of all measured angiotensin metabolites, PRA-S, ALT-S and active ACE2, and lower ACE-S and AA2R than patients in the medical ward at inclusion. …”
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Surrogate-based model parameter optimization in simulations of the West African monsoon by M. Fischer, P. Knippertz, C. Proppe

“…Results show that the ICON model is already generally well-tuned for the WAM system. However, a lower entrainment parameter would lead to a more accurate simulation of accumulated precipitation, averaged 2 <span class="inline-formula">m</span> dew point temperature, and mean sea level pressure over the considered domain (15° W to 15° E, 0 to 25° N). …”
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Comparing cup placement, leg length, and offset discrepancy after total hip arthroplasty between CT-based robotic arm-assisted and navigation systems by Akira Shimizu, Satoshi Murakami, Takayuki Tamai, Yuuki Haga, Tatsuhiko Kutsuna, Tomofumi Kinoshita, Masaki Takao

“…Absolute leg length and absolute discrepancies in the acetabular, femoral, and global offsets were significantly lower in the rTHA group than in the nTHA group (p = 0.042, p = 0.004, p = 0.003, and p = 0.010, respectively). …”
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An analysis of the Policy of Increasing the Salaries of Government Employees Based on the Framework of Kingdon's Multiple Streams (Case Study of Budget Law 1401) by Seyyed Mojtaba Shahraeini, Heidar Najafi, Seyyedamir Abbaszade, Mahdi Khosravi, Iman Akbari

“…To address the identified injustices, subsequent salary and benefits increases should combine a fixed percentage and a fixed amount to ensure that the overall percentage increase is higher for employees with lower salaries.…”
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Regional disparities of full pentavalent vaccine uptake and the determinants in Ethiopia: Mapping and spatial analysis using the EDHS data. by Getasew Mulat Bantie, Melaku Tadege, Teshager Zerihun Nigussie, Ashenafi Abate Woya, Abay Kassa Tekile, Amare Alemu Melese, Simeneh Ayalew, Belay Bezabih Beyene, Gizachew Yismaw Wubetu

“…<h4>Conclusion</h4>Ethiopia's full pentavalent vaccine uptake was far lower than the global target. Older maternal age, maternal education, wealth index, birth order, and giving birth in a health facility were the determinants of full pentavalent vaccine uptake. …”
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Response of high-yielding soybean varieties to water-saturated and drought stress by Purwantoro ., R.D. Purwaningrahayu, H. Kuntyastuti, A. Harsono, N. Nuryati, A. Sulistyo, Z. Yursak, R. Soehendi, Trustinah ., H. Kuswantoro, M.J. Mejaya, D. Harnowo

“…In flooded soil, the Dering 2 and Deja 1 varieties can develop the weight of 100 seeds, number of branches, and plant height as same as in optimal soil moisture, with relatively lower yield reduction compared to other varieties, with stress tolerance index values of 0.66 and 0.54. …”
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The Advances in Utilizing Right Ventricular Function as a Predictor of Peripartum Cardiomyopathy Recovery: A Single Centre Prospective Cohort Study by Akbar MR, Sakasasmita S, Achmad C, Dewi TI, Hasan M, Prameswari HS

“…The recovery rate of patients with initial RV systolic dysfunction is lower than patients with normal RV systolic function (51.5% vs 75.8%, p = 0.016). …”
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Gut microbiota drives colon cancer risk associated with diet: a comparative analysis of meat-based and pesco-vegetarian diets by Carlotta De Filippo, Sofia Chioccioli, Niccolò Meriggi, Antonio Dario Troise, Francesco Vitali, Mariela Mejia Monroy, Serdar Özsezen, Katia Tortora, Aurélie Balvay, Claire Maudet, Nathalie Naud, Edwin Fouché, Charline Buisson, Jacques Dupuy, Valérie Bézirard, Sylvie Chevolleau, Valérie Tondereau, Vassilia Theodorou, Claire Maslo, Perrine Aubry, Camille Etienne, Lisa Giovannelli, Vincenzo Longo, Andrea Scaloni, Duccio Cavalieri, Jildau Bouwman, Fabrice Pierre, Philippe Gérard, Françoise Guéraud, Giovanna Caderni

“…Results In both animal models, the PVD group exhibited significantly lower colon tumorigenesis than the MBD ones, consistent with various CRC biomarkers. …”
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Is intense exercise bad for your mind? Subjective, behavioral and physiological responses to a cognitive effort to failure by Darías Holgado, Ludovic Leubaz, Paolo Ruggeri, Guillermo Borragan, Antonio Luque-Casado, Tristan Bekinschtein, Daniel Sanabria, Nicolas Place

“…However, cognitive task performance was better in the in the phases of low subjective demands. Brain complexity was lower after the physical fatigue condition, indicating a potential shift in physiological states, although neither behavioral performance nor subjective feelings were affected. …”
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Effects of heat stress abatement on behavioral response in lactating dairy cows prior to and following an intramammary lipopolysaccharide infusion by T.N. Marins, R.M. Orellana Rivas, Y-C. Chen, V.H.L.R. Melo, Z. Wang, H. Liu, J. Gao, C.G. Savegnago, A.M. Roper, J.K. Bernard, P. Melendez, S. Tao

“…Before IM-LPS, NC cows had lower ruminating and eating time, and consequently greater inactive time compared with CL cows. …”
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Effects of community-wide vaccination with PCV-7 on pneumococcal nasopharyngeal carriage in the Gambia: a cluster-randomized trial. by Anna Roca, Philip C Hill, John Townend, Uzo Egere, Martin Antonio, Abdoulie Bojang, Abiodun Akisanya, Teresa Litchfield, David E Nsekpong, Claire Oluwalana, Stephen R C Howie, Brian Greenwood, Richard A Adegbola

“…The prevalence of vaccine-type pneumococcal carriage was lower in vaccinated than in control villages among older children (5 y to <15 y of age) and adults (≥15 y of age) at CSS-2 (odds ratio [OR] = 0.15 [95% CI 0.04-0.57] and OR = 0.32 [95% CI 0.10-0.98], respectively) and at CSS-3 (OR = 0.37 [95% CI 0.15-0.90] for older children, and 0% versus 7.6% for adults in vaccinated and control villages, respectively). …”
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Serum ALT activity and its isoenzymes as potential biomarkers for diagnosis of Sarcopenia in older adults: a retrospective, cross-sectional study by Jiangping Zeng, Nannan Li, Jiaying Ge, Huihui Ma, Siqi Sun, Yujie Jing, Chunhua Qian, Ran Cui, Shen Qu, Hui Sheng

“…Results Older adults with sarcopenia exhibited a lower serum ALT activity and a higher ALT1/ALT2 ratio compared to those without sarcopenia. …”
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Phytochemical and Metabolomic Profiles of Ethanolic Extract of Curculigo pilosa Rhizomes for Animal Health by Adenike Abosede Adebisi, Adeyinka Oye Akintunde, Grace Oluwatoyin Tayo, Rufus Olusegun Animashaun

“…The results showed that the ethanolic extracts of C. pilosa had higher concentrations of phenols (9.27 ± 0.55 mg GAE/g), alkaloids (6.22 ± 1.95 g/100g), flavonoids (0.66 ± 0.05 g/100g), and saponins (0.51 ± 0.02 g/100g), but lower concentrations of glycosides (0.06 ± 0.01 g/100g), steroids (0.20 ± 0.02 g/100g), and tannins (0.09 ± 0.01 g/100g). …”
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Racial differences in takotsubo cardiomyopathy outcomes in a large nationwide sample by Raja Zaghlol, Amit K. Dey, Sameer Desale, Ana Barac

“…Additionally, the adjusted risk was lower in AA compared with Caucasians, for cardiogenic shock [odds ratio (OR) 0.61 (0.47–0.78), P < 0.0001], mechanical ventilation [OR 0.8 (0.70–0.92), P = 0.002] and intraaortic balloon pump insertion [OR 0.63 (0.41–0.99), P = 0.04]. …”
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Prevalence and antibiotic resistance patterns of Pseudomonas aeruginosa and Acinetobacter baumannii strains isolated from chicken droppings on poultry farms in Gondar city, Northwe... by Mitkie Tigabie, Muluneh Assefa, Yalewayker Gashaw, Azanaw Amare, Aklilu Ambachew, Sirak Biset, Feleke Moges

“…However, both isolates presented lower resistance rates to piperacillin-tazobactam (4, 9.8 %) and cefepime (7, 17.1 %). …”
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Thiol-Disulfide Homeostasis in Noise-Induced Hearing Loss in Rats by Enes Aydın, Serpil Mungan Durankaya, Osman Yilmaz, Günay Kirkim, Safiye Aktaş, Salim Neşelioğlu, Özcan Erel, Yüksel Olgun, Abdullah Dalgıç

“…Results: Intergroup comparisons by frequency on day 5 of noise exposure showed statistically significantly lower responses in ABR measurements at 8 kHz, 12 kHz, and 16 kHz in group 2 compared to group 3 (P = .003, P=.006, and P=.002). …”
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Systemic Immune-Inflammation Index: A Promising, Non-Invasive Biomarker for Crohn&rsquo;s Disease Activity and Severity Assessment by Deng Y, Fu T, Gao D, Zhou J, Nie X, Wang F, Yu Q

“…Although SII decreased in patients with mucosal healing (p< 0.001), its prognostic accuracy (AUC=0.719) was lower than other biomarkers. However, SII emerged as an independent predictor for CD activity and severity with higher efficacy (AUC=0.774 and 0.807). …”
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Central corneal thickness to adjust IOP measurements by A.V. Korneeva, A.V. Kuroyedov, D.N. Lovpache, I.R. Gazizova, S.Yu. Petrov, I.A. Loskutov

“…CCT is known to affect applanation tonometry readings thus resulting in late glaucoma diagnosis and inadequate IOP-lowering treatment. In patients with thick cornea, ignoring of this parameter will lead to overdiagnosis and unreasonable therapies. …”
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PET imaging of 52Mn labeled DOTATATE and DOTAJR11 by James M. Omweri, Hailey A. Houson, Shannon E. Lynch, Volkan Tekin, Anna G. Sorace, Suzanne E. Lapi

“…The PET images revealed similar biodistribution results, with [52Mn]Mn-DOTATATE showing a significant tumor uptake of 11.16 ± 2.97% ID/g, while [52Mn]Mn-DOTA-JR11 exhibited a lower tumor uptake of 2.11 ± 0.30% ID/g 4 h post-injection. …”
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