Genetic Associations Between Specific Sleep-Related Phenotypes and Idiopathic Sudden Sensorineural Hearing Loss: A Mendelian Randomization Analysis by Li M, He J, Liang Y, Zou F, Gou C, Lv J, Zhang X, Li D, Yu Z

“…However, narcolepsy was an inferred protective factor for ISSNHL. Lower risk of ISSNHL was found in relation to daytime dozing/sleeping (narcolepsy)-related SNPs.Conclusion: This phenomenon may provide a novel and meaningful therapeutic target for ISSNHL based on sleep medicine. …”
Get full text

Productivity and ecological functions of naturally regrown pine forests of the Ukrainian Polissia by Petro Lakyda, Volodymyr Blyshchyk

“…Based on the indicators of basic wood density (341 kg·(m3)-1), the studied stands have a slightly lower density compared to other pine forests of the Ukrainian Polissia zone, which are characterized by high moisture content in wood at a young age, soil conditions (structure, mechanical composition, fertility), which has a significant impact on the formation of late wood, and, consequently, on its density. …”
Get full text

Effects of Different Ratios of Mixed Silage of Licorice Stems and Leaves and Whole Corn on Fermentation Quality, Microbial Diversity, and Aerobic Stability by Qifeng Gao, Yuliang Sun, Limin Tang, Haonan Liu, Chenchen Yang, Yulan Ren, Fangpeng Liu, Chunying Jia, Houjun Yu, Tao Jiang

“…On the 15th day of aerobic exposure, the pH value of the G5Y5 group was significantly lower than that of the other groups (<i>p</i> < 0.05), and the number of lactic acid bacteria was significantly higher than that of the G6Y4 group (<i>p</i> < 0.05). …”
Get full text

Determinants of Dropout From a Virtual Agent–Based App for Insomnia Management in a Self-Selected Sample of Users With Insomnia Symptoms: Longitudinal Study by María Montserrat Sanchez Ortuño, Florian Pecune, Julien Coelho, Jean Arthur Micoulaud-Franchi, Nathalie Salles, Marc Auriacombe, Fuschia Serre, Yannick Levavasseur, Etienne De Sevin, Patricia Sagaspe, Pierre Philip

“…Younger age (adjusted odds ratio [AOR] 0.98, 95% CI 0.97‐0.99), lower education level (compared to middle school; high school: AOR 0.56, 95% CI 0.35‐0.90; bachelor’s degree: AOR 0.35, 95% CI 0.23‐0.52; master’s degree or higher: AOR 0.35, 95% CI 0.22‐0.55), poorer nocturnal sleep (sleep efficiency: AOR 0.64, 95% CI 0.42‐0.96; number of nocturnal awakenings: AOR 1.13, 95% CI 1.04‐1.23), and more severe depression symptoms (AOR 1.12, 95% CI 1.04‐1.21) were significant predictors of dropping out. …”
Get full text

Exploring in vivo human brain metabolism at 10.5 T: Initial insights from MR spectroscopic imaging by Lukas Hingerl, Bernhard Strasser, Simon Schmidt, Korbinian Eckstein, Guglielmo Genovese, Edward J. Auerbach, Andrea Grant, Matt Waks, Andrew Wright, Philipp Lazen, Alireza Sadeghi-Tarakameh, Gilbert Hangel, Fabian Niess, Yigitcan Eryaman, Gregor Adriany, Gregory Metzger, Wolfgang Bogner, Małgorzata Marjańska

“…The spectral quality was outstanding in the parietal and occipital lobes, but lower in other brain regions such as the temporal and frontal lobes. …”
Get full text

An Assessment of Microfinance Institution Services and Performance of Small and Medium Enterprises in Kabale Municipality. by Mugarura, Elijah

“…The study further recommends MFI to lower on their interest rates put on loans they give to SMEs so as not to let loans be too heavy for them to pay back which may hamper their positive contributions on the growth of SMEs. …”
Get full text

Joint Education Provision: A Relief or Challenge to Quality Education Services in Uganda. “A Study in Buganda Region”. by Sempungu, Godfrey

“…The study, in general, investigated the problems that affect the Ugandan school system, reviewed the government's position in lower levels of academia, and gave policy recommendations and suggestions for boosting school performance in light of the current performance. …”
Get full text

Structure of Spatial Correlation Network and Influencing Factors of Urban-Rural Integration in China by Wang Kai, Liu Meilun, Tan Jiaxin, Gan Chang

“…Spatially, it showed a decreasing gradient from east to west, but the gap between the interprovincial urban-rural integration level gradually narrowed, with obvious spatial non-equilibrium. 2) China's urban-rural integration spatial association network became increasingly dense, complex, and close, and the main linkage flows of urban-rural integration occurred between geographically neighboring provinces and cities, such as Shanghai-Jiangsu, Shanghai-Zhejiang, and Beijing-Tianjin. …”
Get full text

Robotic-assisted left thoracic small-incision minimally invasive coronary artery bypass grafting: a case series report by HE Peiling, SONG Yi, YUAN Ye

“…No internal mammary artery injury or transformation of the procedure occurred in these cases， and excellent bridging vessel flow was achieved after anastomosis of the internal mammary artery to left anterior descending branch. …”
Get full text

LRP11 promotes stem-like T cells via MAPK13-mediated TCF1 phosphorylation, enhancing anti-PD1 immunotherapy by Zhishui Chen, Gang Chen, Li Chen, Xiangli Zhao, Lingjuan Sun, Zhibo Ma, Xiaosheng Tan, Yuhao Tu, Jingzeng Wang, Peixiang Lan

“…In an in vivo setting, we employed male C57BL/6J injected with B16 cells or MC38 cells to build a tumor model to assess the effects of LDL and LRP11 inhibitors, LRP11 activators, MAPK13 inhibitors on tumor growth. Flow cytometry was used to measure cell proportions and activation status. …”
Get full text

A Case Study on Multi-Real-Option-Integrated STO-PF Models for Strengthening Capital Structures in Real Estate Development by Jung Kyu Park, Jun Bok Lee, Young Mee Ahn, Ga Young Yoo

“…The traditional discounted cash flow (DCF) method is frequently ill-suited to the dynamic and uncertain nature of long-term real estate projects, particularly in regard to the ability to adapt to market fluctuations. …”
Get full text

A deep learning approach for classifying and predicting children's nutritional status in Ethiopia using LSTM-FC neural networks by Getnet Bogale Begashaw, Temesgen Zewotir, Haile Mekonnen Fenta

“…We used Python's TensorFlow and Keras libraries on a GPU-equipped system for model training. …”
Get full text

Vehicle Detection Algorithm Based on Embedded Video Image Processing in the Background of Information Technology by Rui Liang, Gaoqing Ji

“…With the continuous development of society and the gradual improvement of people’s quality of life, automobiles have gradually become an indispensable means of transportation in people’s lives, resulting in increased traffic flow. However, the old traffic system is still unable to cope with the rapid growth of traffic pressure, and traffic congestion and various accidents occur frequently, which is a huge test for the contemporary intelligent traffic system. …”
Get full text

Rhopalurus junceus scorpion venom induces G2/M cell cycle arrest and apoptotic cell death in human non-small lung cancer cell lines by Alexis Díaz-García, Ángel Garrido, Jenny Laura Ruiz-Fuentes, Tamara Hermosilla, Diego Varela

“…The effects on cell cycle, apoptosis, and cell signaling-related proteins were determined by flow cytometry and WB. Protein fractions responsible for the observed effect were identified using HPLC. …”
Get full text

NCAPD3-mediated ferroptosis of 2,3,5,4’-Tetrahydroxystilbene-2-O-β-D-glucoside inhibits proliferation in T47D cells by Jianfen Shen, Shuo Zhang, Shuo Zhang, Yan Song, Yan Song, Leiming Yang, Leiming Yang, Qi Huang, Qi Huang, Pengyu Wang, Pengyu Wang, Youzhi Zhang, Youzhi Zhang

“…Moreover, cell cycle and ferroptosis were assessed using flow cytometry analysis and WB respectively. Mechanically, cell viability and clone formation was detected using Biochemical kit. …”
Get full text

Comparative Performance of Ante-Mortem Diagnostic Assays for the Identification of <i>Mycobacterium bovis</i>-Infected Domestic Dogs (<i>Canis lupus familiaris</i>) by Conor O’Halloran, Paul Burr, Danielle A. Gunn-Moore, Jayne C. Hope

“…All three serological assays employed in this study (Idexx <i>M. bovis</i> Ab ELISA, [Idexx Laboratories, Westbrook, ME, USA], DPP VetTB lateral flow assay [Chembio, Medford, NY, USA], and comparative PPD ELISA [in-house]) identified seropositive dogs but, overall, the test-positive rate for the serological assays was only one third that of the cellular-based assays. …”
Get full text

Targeted protein degradation through site-specific antibody conjugation with mannose 6-phosphate glycan by Kaori Mukai, Robert Cost, Xin Sheen Zhang, Emily Condiff, Joanne Cotton, Xiaohua Liu, Ekaterina Boudanova, Björn Niebel, Peter Piepenhagen, Xinming Cai, Anna Park, Qun Zhou

“…The M6P-conjugated antibody against a protein of interest (POI) efficiently internalized targeted soluble proteins, such as human tumor necrosis factor (TNF), in both cancer cell lines and human immune cells, through the endo-lysosomal pathway as demonstrated by confocal microscopy and flow cytometry. TNF in cell culture media was significantly depleted after the cells were incubated with the M6P-conjugated antibody. …”
Get full text

Brain connectivity for constructing new face representations in typical adults versus a prosopagnosic patient by Ela I. Olivares, Jorge F. Bosch-Bayard, Ana S. Urraca, Alba Jiménez-Bascuñán, Rolando J. Biscay, Jaime Iglesias

“…Then, we studied the induced EEG activity using ‘isolated effective coherence’ to analyse the intracortical causal information flow among face-sensitive nodes. Initial presentation of external features (E before I), when compared to internal ones, triggered connections encompassing extensively the right-hemisphere face processing pathway [from posterior visual cortices for initial structural analysis, towards both intermediate (occipitotemporal) and high-level (prefrontal) relay stations], in which face-identity is thought to emerge progressively. …”
Get full text

lncRNA-KCNQ1OT1: A Potential Target in Exosomes Derived from Adipose-Derived Stem Cells for the Treatment of Osteoporosis by Shan-zheng Wang, Jun Jia, Chang-hong Chen

“…Cell viability and apoptosis were assessed by Cell Counting Kit-8 (CCK-8) and flow cytometry analysis, respectively. The binding sites between KCNQ1OT1 and miR-141-5p were validated by dual-luciferase reporter assay. …”
Get full text

Economic Feasibility of Ginger Emprit Extract Drink (Zingiber officinale Var. Amarum) using CMC Stabilizer by Ahmad Farhan, Anwar Kasim, Rini B

“…This parameter calculates projected production, revenue and cash flow. Determination of the economic feasibility of the Tempe juice drink with Emprit ginger extract with the Net Present Value (NPV), Incremental Rate of Return (IRR), Net B/C and Pay Back Period (PBP). …”
Get full text