Utility of left atrial and ventricular strain for diagnosis of transthyretin amyloid cardiomyopathy in aortic stenosis by Fumi Oike, Hiroki Usuku, Eiichiro Yamamoto, Kyohei Marume, Seiji Takashio, Masanobu Ishii, Noriaki Tabata, Koichiro Fujisue, Kenshi Yamanaga, Daisuke Sueta, Shinsuke Hanatani, Yuichiro Arima, Satoshi Araki, Seitaro Oda, Hiroaki Kawano, Hirofumi Soejima, Kenichi Matsushita, Mitsuharu Ueda, Toshihiro Fukui, Kenichi Tsujita

“…In 2D speckle tracking echocardiography, the relative apical longitudinal strain (LS) index (RapLSI) [apical LS/ (basal LS + mid LS)] was significantly higher (1.09 ± 0.49 vs. 0.78 ± 0.23, P < 0.05) and the peak longitudinal strain rate (LSR) in LA was significantly lower in the 99mTc‐PYP scintigraphy‐positive than scintigraphy‐negative group (0.36 ± 0.14 vs. 0.55 ± 0.20 s−1, P < 0.05). …”
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Global prevalence of Eimeria species in goats: a systematic review and meta-analysis by Endris A. Ali, Abdul Ghafar, Juan C. Angeles-Hernandez, Muhammad Yaseen, Muhammad Yaseen, Charles G. Gauci, Ian Beveridge, Sandra Baxendell, Abdul Jabbar

“…The subgroup of studies conducted in 2000 or later presented a lower prevalence of 59.6% (95% CI: 54.7–64.3). Studies with a score of 5–7 had a significantly higher prevalence (72.4, 95% CI: 66.2–78.2) than studies with low or medium scores (p &lt; 0.01). …”
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Programmed Cell Death Ligand 1 (PD-L1) and major Histocompatibility Complex Class I (MHC Class I) Expression Patterns and Their Pathologic Associations in triple-Negative Breast Ca... by Kaewkedsri P, Intarawichian P, Jessadapattarakul S, Kunprom W, Koonmee S, Thanee M, Somintara O, Wongbuddha A, Chadbunchachai P, Nawapun S, Aphivatanasiri C

“…Older FFPE blocks (2008– 2018) showed lower PD-L1 expression than newer blocks (2019– 2021). …”
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Un port rural antique de fond d’estuaire à Blainville-sur-Orne (Calvados) by Cécile Allinne

“…This tripartite article reports on the state of investigations carried out in a small Roman port in the lower Dan valley, at Blainville-sur-Orne, occupied from the end of the 1st c. …”
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Inhibition of Vibrio parahaemolyticus infection in whiteleg shrimp reared in a biofloc system with different volumes by Surandha Bako, Widanarni Widanarni, Julie Ekasari, Munti Yuhana

“…The results showed that the presumptive Vibrio count (PVC) and the population of V. parahaemolyticus in the biofloc treatments were significantly lower than the positive control (p<0.05). Furthermore, the biofloc treatment with a volume of 15 mL/L demonstrated the best results compared to other treatments in decreasing PVC and V. parahaemolyticus population as evidenced by the immune response, survival rate, and growth performance of whiteleg shrimp.   …”
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Optimization of chemical transfection in airway epithelial cell lines by Tony J. F. Guo, Wan Yi Liang, Gurpreet K. Singhera, Jasmine Memar Vaghri, Janice M. Leung, Del R. Dorscheid

“…In NCI-H292, jetOPTIMUS yielded a lower transfection efficiency (22.6 ± 1.2%) with a significant reduction in viability (28.3 ± 0.9%, p < 0.0001). …”
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High SUVs Have More Robust Repeatability in Patients with Metastatic Prostate Cancer: Results from a Prospective Test-Retest Cohort Imaged with 18F-DCFPyL by Rudolf A. Werner, Bilêl Habacha, Susanne Lütje, Lena Bundschuh, Takahiro Higuchi, Philipp Hartrampf, Sebastian E. Serfling, Thorsten Derlin, Constantin Lapa, Andreas K. Buck, Markus Essler, Kenneth J. Pienta, Mario A. Eisenberger, Mark C. Markowski, Laura Shinehouse, Rehab AbdAllah, Ali Salavati, Martin A. Lodge, Martin G. Pomper, Michael A. Gorin, Ralph A. Bundschuh, Steven P. Rowe

“…High SUVs showed significantly improved wCOV relative to lower SUVs (P<0.0001), indicating that high SUVs are more repeatable, relative to the magnitude of the underlying SUV. …”
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Increased DHEAS and Decreased Total Testosterone Serum Levels in a Subset of Men with Early-Onset Androgenetic Alopecia: Does a Male PCOS-Equivalent Exist? by Rossella Cannarella, Rosita A. Condorelli, Federica Dall’Oglio, Sandro La Vignera, Laura M. Mongioì, Giuseppe Micali, Aldo E. Calogero

“…Group 1 had higher BMI (27.9 ± 3.8 vs. 23.7 ± 3.8 ml; P<0.05), fat-mass percentage (17.5 ± 4.1 vs. 13.2 ± 5.3; P<0.05), HOMA index (2.5 ± 1.8 vs. 1.5 ± 0.7; P<0.05), DHEAS (323.3 ± 112.6 vs. 257.8 ± 107.1 μg/dl; P<0.05), seminal fluid volume (4.2 ± 2.8 vs. 2.8 ± 1.3 ml; P<0.05), lower TT (5.16 ± 1.70 vs. 6.47 ± 4.30 ng/ml; P=0.016), and left TV (12.3 ± 2.8 vs. 15.0 ± 4.3 ml; P<0.05) compared to controls. …”
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Lenvatinib Therapy in Patients with Unresectable Hepatocellular Carcinoma in Real Clinical Practice by V. V. Petkau, A. V. Sultanbaev, K. V. Menshikov, A. S. Antipin, M. V. Volkonsky, V. M. Filippova, Yu. V. Vasilyeva, A. A. Tarkhanov, M. R. Mukhitova, M. Zh. Murzalina, A. R. Safarova

“…Patients with macroscopic portal vein invasion had a significantly lower PFS compared with those lacking this complication: 3.97 (0.00-8.07) vs. 11.1 (8.46-13.7), p = 0.053. …”
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Degradation of low-density polyethylene by a novel strain of bacteria isolated from the plastisphere of marine ecosystems by F.A. Febria, A. Syafrita, A. Putra, H. Hidayat, C. Febrion

“…Fourier transform infrared observations showed variations in transmittance and wavenumbers, indicating changes in chemical bonds or functional groups in the low-density polyethylene film which caused it to become brittle and break down into smaller fragments with a lower molecular weight, making it easier for bacteria to digest. …”
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Integrated microbiome, transcriptome and metabolome insight into the alleviating mechanisms of sheep milk in a DSS-induced colitis mouse model by Wenna Yao, Ruilin Du, Shuo Yan, Teligun Bao, Huimin Zhang, Fang Yang, Yue Xue, Yulong Zhao, Siqin Bao, Xihe Li, Yongli Song

“…In the DSS group, LGR5, KI67, and MUC2 were significantly lower than in the CON group, but the SM treatment increased these protein expression levels. …”
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THE ORGANIZATION WORKS TO IMPROVE THE CLINICAL AND ECONOMIC OUTCOMES OF CARE FOR PROSTATE CANCER by O. I. Apolikhin, A. V. Sivkov, I. V. Chernishov, M. I. Katibov, O. V. Zolotukhin, I. A. Shaderkin, S. A. Leonov, D. A. Vojtko, M. Y. Prosyannikov

“…The purpose of this stage is a screening questionnaire for men of Voronezh region between the ages of 45 to 74 years using a modified international questionnaire lower urinary tract symptoms (IPSS) and nomograms individual risk of prostate cancer (SWOP №1).            …”
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Digital Surveillance of Mental Health Care Services in Saudi Arabia: Cross-Sectional Study of National e-Referral System Data by Abdullah A Alharbi, Nawfal A Aljerian, Meshary S Binhotan, Hani A Alghamdi, Ali K Alsultan, Mohammed S Arafat, Abdulrahman Aldhabib, Yasser A Alaska, Eid B Alwahbi, Mohammed A Muaddi, Ahmad Y Alqassim, Ronnie D Horner

“…The utilization of the mental health e-referral system varied across regions, with the Northern Border and Albaha regions showing the highest rates, while Madinah, Eastern, and Riyadh regions demonstrated lower use. Temporal analysis showed almost similar monthly patterns in 2020 and 2021. …”
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Tobacco Use, Risk Perceptions, and Characteristics of Adults Who Used a Heated Tobacco Product (IQOS) in the United States: Cross-Sectional Survey Study by Hui G Cheng, Brendan Noggle, Andrea R Vansickel, Edward G Largo, Pierpaolo Magnani

“…Among all AUIs, over 563 (81.8%) had never used a cessation treatment or had not used it in the past 12 months, and 555 (80.7%) AUIs demonstrated a correct understanding of the MRTP message and AUIs perceived THS as having a lower risk than cigarettes (43.8 vs 64.4 on a 100-point composite score scale). …”
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Integrated Microbiome and Metabolome Analysis Reveals Correlations Between Gut Microbiota Components and Metabolic Profiles in Mice With Mitoxantrone-Induced Cardiotoxicity by Zhang Q, Liang D, Zhang C, Ye L, Sun P, Zhu H, Zhao Y, Li Y, Guan Y, Zhang H

“…Additionally, MTX increased Romboutsia, Enterococcus, and Turicibacter abundances and lowered norank_f__Muribaculaceae, Alistipes, Odoribacter, norank_f__Lachnospiraceae, norank_f__Ruminococcaceae, norank_f__Oscillospiraceae, unclassified_f__Ruminococcaceae, NK4A214_group, Colidextribacter, norank_f__norank_o__Clostridia_vadinBB60_group, Rikenella, and Anaerotruncus abundances. …”
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Unveiling Cuproptosis-Driven Molecular Clusters and Immune Dysregulation in Ankylosing Spondylitis by Wei B, Wang S, Li S, Gu Q, Yue Q, Tang Z, Zhang J, Liu W

“…According to the blood serum samples of AS patients and controls, PELI1 had a higher expression level (AUC = 0.703, p = 0.07), while ICAM2 and RANGAP1 had lower expression levels (AUC = 0.724, 0.745, and p = 0.011, 0.000, respectively) in AS patients.Conclusion: We explored the correlation of cuproptosis in AS, and developed the optimal machine learning model to identify high-risk genes associated with AS. …”
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Immune Modulation Effect of Administration of Rice Bran Extract with Increased Solubility Fermented by <i>Lentinus edodes</i> UBC-V88 in Cyclophosphamide-Treated Mice Model by Gi-Jung Kim, Yelim Jang, Ji-Yoon Hong, Kyoung-Tae Kwon, Dae-Weon Kim, Dae-Jung Kang, Sung-Joo Hwang, Jung-Yun Lee, Emmanouil Apostolidis, Young-In Kwon

“…The potential immunomodulatory effect of fermented rice bran (FRB) and processed rice bran (RB) was evaluated using male BALB/c mice whose immunity was lowered by Cyclophosphamide (CY). The changes in the weight of the thymus and the spleen, immunoglobulins, and cytokine expressions were measured as biomarkers of immunomodulating potential after 14 days of oral administration of FRB and RB (0.5 g/kg-body weight (b.w.), respectively). …”
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Improving Outcomes and Quality of Life for Patients With Hand and Foot Eczema: Randomized Study of a Patient-Centered Monitoring App by Aimee Bruch, Wanja Weigandt, Yannic Schardt, Raphael Herr, Johannes Benecke, Astrid Schmieder

“…We were able to demonstrate a significant correlation between the HECSI calculated based on pictures uploaded by patients through the app and the HECSI assessed during personal visits (ρ=0.885; P<.001), despite the potentially lower image quality of the pictures uploaded through the app. …”
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Cardiovascular disease attenuates the protective effect of folate on global cognitive function in an elderly population: a cross-sectional study by Jianqiang Zhang, Di Yue, Huifeng Zhang

“…According to tertile groups, compared with participants in the lowest tertile, individuals in the highest tertile of total dietary folate levels (OR 0.67, 95% CI 0.48–0.94, P = 0.02), folic acid levels (OR 0.57, 95% CI 0.38–0.86, P = 0.01), and RBC folate levels (OR 0.62, 95% CI 0.44–0.85, P = 0.004) had significantly lower odds of having CoI. The RCS showed a linear negative correlation between RBC folate levels and CoI. …”
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Impact of hepatic steatosis on the efficacy of antiviral treatment for chronic hepatitis B and the establishment of predictive model: a cohort study by Guanghui Ren, Kaining Jia, Shi Yin, Yunpeng Guan, Qingwei Cong, Ying Zhu

“…Factors like younger age, NAs with PEG IFNα therapy, lower initial HBsAg levels, and MASLD presence predict treatment success. …”
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