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  1. 28041

    Integrating biomarkers for hemostatic disorders into computational models of blood clot formation: A systematic review by Mohamad Al Bannoud, Tiago Dias Martins, Silmara Aparecida de Lima Montalvão, Joyce Maria Annichino-Bizzacchi, Rubens Maciel Filho, Maria Regina Wolf Maciel

    Published 2024-12-01
    “…Eligibility criteria included mathematical models of thrombin generation, blood clotting, or fibrin formation under flow, incorporating at least one of these biomarkers. …”
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  2. 28042

    Role of Toll-Like Receptor 2 in Regulation of T-Helper Immune Response in Chronic Obstructive Pulmonary Disease by Karolina A. Sidletskaya, Tatyana I. Vitkina, Yulia K. Denisenko, Elena E. Mineeva

    Published 2021-01-01
    “…Serum levels of Th1 (TNF-α and IFN-γ), Th2 (IL-4), Th17 (IL-6 and IL-17A), Treg (IL-10) cytokines, and the percentage of peripheral blood Th cells expressing TLR2 (CD4+CD282+) were assessed by flow cytometry. Serum concentrations of IL-21 (Th17) and TGF-β1 (Treg) were measured using the ELISA method. …”
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  3. 28043

    Th2-Immune Polarizing and Anti-Inflammatory Properties of Insulin Are Not Effective in Type 2 Diabetic Pregnancy by Adnette Fagninou, Magloire Pandoua Nekoua, Darius Sossou, Kabirou Moutairou, Nadine Fievet, Akadiri Yessoufou

    Published 2020-01-01
    “…Immune cell subpopulation frequencies were determined in blood using flow cytometry. The proliferative capacity of T cells was performed, and serum and cell culture supernatant cytokine levels were also quantified. …”
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  4. 28044

    Effect of noninvasive respiratory support on interstitial lung disease with acute respiratory failure: A systematic review and meta-analysis by Natthawan Sanguanwong, Nattawat Jantarangsi, Jinjuta Ngeyvijit, Natthida Owattanapanich, Vorakamol Phoophiboon

    Published 2023-11-01
    “…# Background Primary studies have demonstrated the effectiveness of noninvasive respiratory supports, including noninvasive positive pressure ventilation (NIPPV) and high flow nasal cannula (HFNC), for improving oxygenation and ventilation in patients with interstitial lung diseases (ILDs) and acute respiratory failure (ARF). …”
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  5. 28045

    Multi-scale hydraulic graph neural networks for flood modelling by R. Bentivoglio, E. Isufi, S. N. Jonkman, R. Taormina

    Published 2025-01-01
    “…First, they cannot model rapid differences in flow propagation speeds; secondly, they can face instabilities during training when using a large number of layers, needed for effective modelling; third, they cannot accommodate time-varying boundary conditions; and fourth, they require initial conditions from a numerical solver. …”
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  6. 28046

    Evaluation of B cell related markers and autoantibodies in rheumatoid arthritis patients treated with abatacept by Ting Wang, Natalia V. Giltiay, Christian Lood, Ning Wang, Bobby Kwanghoon Han

    Published 2025-01-01
    “…Peripheral blood mononuclear cells were isolated and analysed for T cell and B cell subsets by flow cytometry. Patients were genotyped for human leukocyte antigen (HLA)-DRB1 shared epitope (SE) alleles. …”
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  7. 28047

    Differentiation between glioblastoma and solitary brain metastases using perfusion and amide proton transfer weighted MRI by Malte Knutsson, Tim Salomonsson, Faris Durmo, Emelie Ryd Johansson, Anina Seidemo, Jimmy Lätt, Anna Rydelius, Sara Kinhult, Elisabet Englund, Johan Bengzon, Peter C. M. van Zijl, Peter C. M. van Zijl, Linda Knutsson, Linda Knutsson, Linda Knutsson, Pia C. Sundgren, Pia C. Sundgren, Pia C. Sundgren

    Published 2025-02-01
    “…The objective of this study was to assess whether amide proton transfer weighted (APTw) MRI alone or combined with dynamic susceptibility contrast (DSC) MRI parameters, including cerebral blood volume (CBV), cerebral blood flow (CBF), and leakage parameter (K2) measurements, can differentiate GBM from MET.MethodsAPTw MRI and DSC-MRI were performed on 18 patients diagnosed with GBM (N = 10) or MET (N = 8). …”
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  8. 28048

    Spirituality-Based Intervention in Hypertension: EFfects on Blood PrEssure and EndotheliaL Function—FEEL Trial Results by Maria Emília Figueiredo Teixeira, Weimar Kunz Sebba Barroso, Andréa Araújo Brandão, Ana Luiza Lima Sousa, Roberto Esporcatte, Mário Henrique Elesbão de Borba, Ana Clara Neri Ávila Baleeiro, Beatriz Caldas Gonçalves, Enzo Inumaru, Enzo Mata de Sousa, Giovana Barros Leal, Henrique Soares de Araújo Pereira Farias, Juliana Alves de Souza, Lure Emilly Barreto da Silva, Matheus Canguçu de Paiva Queiroz, Frederico Rafael Moreira, Priscila Valverde de Oliveira Vitorino, John Eikelboom, Álvaro Avezum

    Published 2025-01-01
    “…Following baseline evaluation, including lifestyle questionnaires, and measurements of office and central blood pressure (BP), home blood pressure monitoring (HBPM) and flow mediated dilation (FMD), patients were randomized to a spirituality-based intervention, which included training for forgiveness, gratitude, optimism, and life purpose delivered by daily WhatsApp communications, or to the control group (CG). …”
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  9. 28049

    Study on the Key Influential Factors on Water Huff-n-Puff in Ultralow-Permeability Reservoir by Xiaoyan Wang, Kun Xie, Jie Zhang, Yong Zhang, Yang Zhang, Wei Wang, Xi Yan, Fengxiang Zhao

    Published 2021-01-01
    “…Higher reservoir energy is good for oil flow, and better physical property can improve the displacement effect and imbibition function of injection solution. …”
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  10. 28050

    Research on Territorial Spatial Use Regulation, Land Element Allocation, and Regional Fiscal Transfer Payments: An Empirical Study of the Yangtze River Economic Belt by Wanmin Zhao, Yijia Gao, Aihui Ma

    Published 2025-01-01
    “…The regulation of land use within territorial spaces has, to some extent, inhibited the free flow of land resources, giving rise to the dilemma of substantial losses and profits within and outside regulated areas. …”
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  11. 28051

    Curdione combined with borneol treats bacterial mixed HPV infection by regulating the crosstalk among immune cells by Jingwei Liu, Jingwei Liu, Tong Shu, Yiheng Mu, Wanlin Zheng, Xiaohuan Lu, Xiaohuan Lu, Hong Tao, Hong Tao

    Published 2025-01-01
    “…Bioinformatics and network pharmacology approaches were employed to identify therapeutic targets of Baofukang suppository for BV/HPV co-infections. qRT-PCR, Western blot, immunofluorescence staining, and flow cytometry were utilized to validate the therapeutic targets of curdione and borneol, along with the associated immune molecular changes. …”
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  12. 28052
  13. 28053

    S100A13-driven interaction between pancreatic adenocarcinoma cells and cancer-associated fibroblasts promotes tumor progression through calcium signaling by Liuyuan Xia, Xin Guo, Dong Lu, Yixin Jiang, Xiaohui Liang, Yiwen Shen, Jiayi Lin, Lijun Zhang, Hongzhuan Chen, Jinmei Jin, Xin Luan, Weidong Zhang

    Published 2025-01-01
    “…Cellular viability and apoptosis rates were evaluated through CCK-8 and flow cytometry tests, respectively. Additionally, the wound healing and migration assays were conducted to assess the invasive and metastatic capabilities. …”
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  14. 28054
  15. 28055

    A blinded comparison of fluticasone propionate with budesonide via powder devices in adult patients with moderate-to-severe asthma: a clinical evaluation by N. Ringdal, P. Swinburn, R. Backman, P. Plaschke, A. P. Sips, P. Kjaersgaard, G. Bratten, T. A. J. Harris

    Published 1996-01-01
    “…Assessment of mean morning peak expiratory flow (PEF) over the 12-week treatment period revealed a statistically significant difference in efficacy between FP 800 μg daily and BUD 1600 μg daily in favour of FP (p = 0.003), with an overall improvement of 20.9 l/min with FP compared with 12.4 l/min on BUD. …”
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  16. 28056

    Design and Mechanism Study of 6c, a Novel Artesunate Derivatives, for Anti-Hepatocellular Carcinoma by Xiong SS

    Published 2025-01-01
    “…The effect of 6c on cycle arrest was detected by flow cytometry. Molecular simulations of several hybrids with vascular endothelial growth factor receptor 2 (VEGFR-2) and Transferrin receptor protein 1 (TFR1) were performed using MOE molecular docking software.Results: A series of new artemisinin-4-(4-substituted phenoxy) pyridine derivatives were synthesized and their anticancer activities were tested in three lines of hepatocellular carcinoma (HCC) cells. …”
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  17. 28057

    Development and assessment of an intestinal tri-cellular model to investigate the pro/anti-inflammatory potential of digested foods by Marina Ramal-Sanchez, Chiara Bravo-Trippetta, Veronica D’Antonio, Elena Corvaglia, Angela A. M. Kämpfer, Roel P. F. Schins, Mauro Serafini, Donato Angelino

    Published 2025-02-01
    “…Additionally, ZO-1 protein from the tight junctions of epithelial cells was analyzed by flow cytometry. The results indicated that 100 nM PMA added to the whole model for 20 h was the best stressor to simulate a mild-inflammatory status of the gut. …”
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  18. 28058

    Practice, governance, and culture characteristics of lived experience organisations, and evidence of efficacy: A scoping review protocol. by Jessica E Opie, An Vuong, Alexandra Macafee, Hanan Khalil, Natalie Pearce, Erandathie Jayakody, Christropher Maylea, Jennifer E McIntosh

    Published 2023-01-01
    “…Results will be presented in a Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews flow chart. Results will be presented in tabular form and narratively synthesized. …”
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  19. 28059

    Cerebral vascular shunting and oxygen metabolism in sickle cell disease by Alexander K. Song, Wesley T. Richerson, Megan A. Aumann, Spencer L. Waddle, R. Sky Jones, Samantha Davis, Lauren Milner, Chelsea Custer, L. Taylor Davis, Sumit Pruthi, Dann Martin, Lori C. Jordan, Manus J. Donahue

    Published 2025-01-01
    “…Vascular shunting was assessed in each patient using a previously published ordinal venous hyperintensity score (VHS) of 0, 1, or 2 on cerebral blood flow-weighted MRI. Participants with VHS of 2, indicative of the most rapid arteriovenous transit, had significantly reduced blood oxygen content (CaO2; 10.90 ± 1.69 mL O2/100 mL blood), oxygen extraction fraction (OEF; 33.52% ± 5.54%), and cerebral metabolic rate of oxygen consumption (CMRO2; 2.91 ± 0.69 mL O2/100 g tissue per minute) compared with their counterparts with VHS = 0 (CaO2 = 12.42 ± 1.58 mL O2/100 mL blood; OEF = 39.03% ± 3.80%; CMRO2 = 3.77 ± 0.84 mL O2/100 g tissue per minute) or VHS = 1 (CaO2 = 11.86 ± 1.73 mL O2/100 mL blood; OEF = 36.37% ± 5.11%; CMRO2 = 3.59 ± 0.78 mL O2/100 g tissue per minute). …”
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  20. 28060

    A Quick Method for Appraising Pore Connectivity and Ultimate Imbibed Porosity in Shale Reservoirs by Ziqing Hong, Mianmo Meng, Kong Deng, Jingwen Bao, Qianyou Wang, Xingchen Liu

    Published 2025-01-01
    “…Pore connectivity and ultimate imbibed porosity are two important parameters used to assess the shale oil reservoir property, the proper appraising of which could facilitate the efficient flow of oil from the matrix and an improvement in recovery efficiency. …”
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