Genetic insights into psychotic major depressive disorder: bridging the mood-psychotic disorder spectrumResearch in context by Thuy-Dung Nguyen, Joeri J. Meijsen, Robert Sigström, Ralf Kuja-Halkola, Ying Xiong, Arvid Harder, Kaarina Kowalec, Joëlle A. Pasman, Carolina Scarpa, Elin Hörbeck, Lina Jonsson, Sara Hägg, Niamh Mullins, Kevin S. O’Connell, Christina Dalman, Dorte Helenius, Richard Zetterberg, Henrik Larsson, Paul Lichtenstein, Ole A. Andreassen, Thomas Werge, Alfonso Buil, Mikael Landén, Patrick F. Sullivan, Yi Lu

“…Within 30,000 genotyped MDD cases, individuals with psychotic MDD had higher mean PRS for schizophrenia and BD but a lower MDD PRS than non-psychotic MDD. PRS for BD type-I was associated with increased odds of psychotic MDD, while BD type-II PRS showed no significant association with psychotic MDD. …”
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Investigation of geographic disparities and temporal changes of non-gestational diabetes-related emergency department visits in Florida: a retrospective ecological study by Md Marufuzzaman Khan, Agricola Odoi

“…Counties with high percentages of non-Hispanic Black, current smokers, uninsured, and populations with diabetes had significantly higher non-gestational diabetes-related ED visit rates, while counties with high percentages of married populations had significantly lower ED visit rates. Conclusions The study findings confirm geographic disparities of non-gestational diabetes-related ED visit rates in Florida with high-rate areas observed in the rural northern and south-central parts of the state. …”
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β-glucan attenuates intestinal ischemia-reperfusion injury in mice by promoting glucagon-like peptide-1 secretion by WANG Wei, HAN Ben, SUN Lihua

“…While, the mRNA levels of the 3 molecules were obviously higher and the Chiu's score was lower in the II/R+BG group than the II/R group (P<0.05). …”
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Medical student experiences of Case-Based Learning (CBL) at a multicultural medical school by Catherine Bruen, Jan Illing, Ronan Daly, Frances Meagher, Caroline Delany, Gozie Offiah, Sally Doherty, Ellen Stuart, Martina Crehan, Helen Kelly

“…We identified six learning points to highlight features of CBL that support active learning: CBL increased contact with peers and facilitated student bonding; students need to feel psychologically safe to participate; prior learning can enhance confidence to participate; facilitators need to be aware of their role, know about psychological safety, and manage student participation including the dominant voice; some students have a lower tolerance of uncertainty and need additional clarity at the end either via the facilitator or additional notes that provide the key learning points to take away; students became more engaged when a case is aligned to a real patient case giving it authenticity. …”
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Diagnostic Decision-Making Variability Between Novice and Expert Optometrists for Glaucoma: Comparative Analysis to Inform AI System Design by Faisal Ghaffar, Nadine M. Furtado, Imad Ali, Catherine Burns

“…ResultsBoth groups showed lower concordance rates with clinical diagnosis, with experts showing almost double (7/35, 20%) concordance rates with limited data in comparison to novices (7/69, 10%), highlighting the impact of experience and data availability on clinical judgment; this rate increased to nearly 40% for both groups (experts: 5/12, 42% and novices: 8/21, 42%) when they had access to complete historical data of the patient. …”
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A Rare Case of Spontaneous Heterotopic Pregnancy at 12&nbsp;weeks of Gestation Following Natural Conception With Literature Review by Wang F, Xu Y, Dong X, Jiang P, Yu QQ

“…Postoperative β-HCG levels were 49,213 mIU/mL and 57,577 mIU/mL on the second and third days, respectively.Conclusion: Clinicians should maintain vigilance for heterotopic pregnancy, especially in the absence of infertility treatments or known risk factors. Lower quadrant abdominal or pelvic pain should prompt consideration of heterotopic pregnancy, as the presence of an intrauterine pregnancy does not exclude a concurrent ectopic pregnancy.Keywords: ectopic pregnancy, heterotopic pregnancy, laparoscopy, spontaneous pregnancy…”
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Growth response of <i>Emiliania huxleyi</i> to ocean alkalinity enhancement by G. Faucher, M. Haunost, A. J. Paul, A. U. C. Tietz, U. Riebesell

“…Due to the decreasing growth rate in response to alkalinity enhancement, total carbonate formation was lower.</p> <p>OAE is rapidly advancing and has already reached the field-testing stage. …”
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Typologie et caractéristiques des pâturages de la commune urbaine de Téra dans l'ouest du Niger by Hamza Seydou Korombé, Idrissa Soumana, Abdoul Aziz Maman Lawal, Ibrahim Djibo, Sanoussi Atta

“…Les différences entre les pâturages et l’homogénéité de la flore au sein de chaque pâturage ont été analysées. …”
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Sole and Combined Application of Biodigestate, N, P, and K Fertilizers: Impacts on Soil Chemical Properties and Maize Performance by Aruna Olasekan Adekiya, Olufunmilayo Titilayo Ande, Samuel Olatunde Dahunsi, Joshua Ogunwole

“…High fertilizer rates (N2, P2, and K2) significantly enhanced soil chemical properties and growth parameters, but lower rates (N1, P1, and K1) resulted in higher maize yield. …”
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Nonspecific response of Lake Baikal phytoplankton to anthropogenic impact by A. A. Nikonova, S. S. Vorobyeva

“…Using the method of gas chromatography, we showed a lower (up to 15 %) content of polyunsaturated fatty acids in phytoplankton characterized by stress occurrence. …”
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Levels of growth factors in the lungs affected by cancer with preventive effect of 1,3-diethylbenzimidazolium triiodide in the experiment by E. M. Frantsiyants, I. V. Kaplieva, L. K. Trepitaki

“…Lung tissues of intact females showed 1.4 times (p&lt;0.05) lower VEGF-А and 3.3 times higher sVEGF-R1, compared to males. …”
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Species Diversity, Biomass Production and Carbon Sequestration Potential in the Protected Area of Uttarakhand, India by Geetanjali Upadhyay, Lalit M. Tewari, Ashish Tewari, Naveen Chandra Pandey, Sheetal Koranga, Zishan Ahmad Wani, Geeta Tewari, Ravi K. Chaturvedi

“…The <i>Quercus leucotrichophora</i>, <i>Rhododendron arboreum</i> and <i>Quercus floribunda</i> (QL-RA-QF) community(higher altitudinal zone) exhibited the highest tree biomass (568.8 Mg ha⁻¹), while the (<i>Pinus roxburghii</i> and <i>Quercus leucotrichophora</i>) PR-QL (N) community (lower altitudinal zone) in the north aspect showed the lowest (265.7 Mg ha⁻¹). …”
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Identifying the Dimensions and Consequences of Digital Customer Experience: A Phenomenological Study by Fatemeh Eslahi, Seyed Mohammad Reza Mirahmadi, Mojtaba Aghajani

“…Utilizing interactive capabilities enables direct contact with consumers, resulting in lower costs, increased productivity, enhanced satisfaction with internet purchasing, higher repurchase intentions, and ultimately, a more pleasant consumer experience. …”
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Efficacy and prognosis of dapagliflozin in the treatment of patients with acute myocardial infarction complicated with type 2 diabetes in Xining area by Jinping Chai, Delian Li, Yanmin Liu, Xiaoling Su

“…However, up to dapagliflozin group of patients after discharge significantly lower than the control group, the incidence of cardiovascular adverse events at dapagliflozin group of 4 cases of heart failure and cardiovascular death in 1 case and control group in heart failure 13 cases, 10 cases of cardiovascular death, cerebral hemorrhage 2 cases died. …”
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Intracalvariosseous injection: an approach for central nervous system drug delivery through skull bone marrow with a preclinical research in strokeResearch in context by Wenqian Liu, Mo Yang, Nanxing Wang, Xiangrong Liu, Chaoyu Wang, Kaibin Shi, Fu-Dong Shi, Yuesong Pan, Mingjun Zhang, Zhiwei Sun, Yongjun Wang, Yilong Wang

“…In the treatment of stroke with neuroprotective agents, although the drug dosage of ICO injection was lower than intravenous injection, drug accumulation in the brain increased after ICO injection, which helped repair nerve damage, reduce neuronal apoptosis, and decrease the expression of inflammatory factors. …”
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DYSFUNCTION OF MODERN RUSSIAN INSTITUTES OF STATE AWARDS IN THE SPHERE OF EDUCATION AND SCIENCE by Aleksey V. Ruchkin

“…Moreover, it is necessary to lower qualifications on presence of the certain experience and to remove some other restrictions for the state recognition. …”
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The prognostic importance of the pan-immune-inflammation value in patients with septic shock by Yasemin Bozkurt Turan

“…Results Median age, presence of hypertension, Acute Physiology and Chronic Health Evaluation II (APACHE II) levels, and neutrophil, monocyte, and platelet counts were lower in the low-PIV group than in the high-PIV group (p < 0.05). …”
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Coagulation Parameters in Elderly Patients with Severe Pneumonia: Correlation with Disease Severity and Prognosis by Zhang Q, Liu Y, Tong C, Zhang L, Li R, Guo W, Li J

“…Non-survivors had significantly higher PT, APTT and D-dimer levels and lower FIB levels than survivors (p < 0.05). Multivariate logistic regression analysis showed that elevated PT (odds ratio [OR] = 1.218, 95% confidence interval [CI]: 1.076– 1.379, p = 0.002) and D-dimer (OR = 1.109, 95% CI: 1.032– 1.192, p = 0.005) were independent risk factors for 28-day mortality. …”
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Comparisons of open surgical repair, thoracic endovascular aortic repair, and optimal medical therapy for acute and subacute type B aortic dissection: a systematic review and meta-... by Jianping Liu, Xiaohong Chen, Juan Xia, Long Tang, Yongheng Zhang, Lin Cao, Yong Zheng

“…Moreover, OSR versus TEVAR showed an increased risk of in-hospital mortality (OR: 2.67; 95%CI: 1.92–3.72; P < 0.001), acute renal failure (OR: 1.98; 95%CI: 1.61–2.42; P < 0.001), myocardial infaraction (OR: 2.76; 95%CI: 1.64–4.65; P < 0.001), respiratory failure (OR: 2.19; 95%CI: 1.73–2.76; P < 0.001), or bleeding (OR: 1.88; 95%CI: 1.33–2.67; P < 0.001), and lower risk of reintervention (OR: 0.30; 95%CI: 0.10–0.89; P = 0.030). …”
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Potential pharmacological effect of Quercetin Phytosome™ in the management of hyperuricemia: results from real-life clinical studies by Francesco Di Pierro, Francesco Di Pierro, Francesco Di Pierro, Fazle Rabbani, Meherullah Tareen, Roohi Nigar, Amjad Khan, Nicola Zerbinati, Maria L. Tanda, Massimiliano Cazzaniga, Alexander Bertuccioli, Alexander Bertuccioli, Paolo Falasca, Gabriele Damiani, Nicola Villanova

“…Additionally, triglyceride-lowering benefits were evident, particularly in metabolically compromised individuals (Cohorts 2 and 3), where these effects were statistically significant. …”
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