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27481
Investigation of the Aquifer Protective Capacity and Groundwater Quality around Some Open Dumpsites in Sapele Delta State, Nigeria
Published 2018-01-01“…However, the aquifer shows good transmissivity, an indication that if it is contaminated, the contaminants will circulate the aquifer at a high rate. The groundwater flows in the northeast (NE) direction, thereby recharging river Ethiope. …”
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27482
Anti-TNBC effects of Lappaol F by targeting epithelial-mesenchymal transition via regulation of GSK-3β/YAP/β-catenin and PI3K/AKT pathways
Published 2025-02-01“…The present study aimed to reveal the potential mechanism of LAF against TNBC by in vivo and in vitro experiments.MethodsIn situ, transplantation-induced MDA-MB-231 solid tumor model in NCG mice and cultured MDA-MB-231 and Hs-578T cells were used to evaluate the anti-TNBC effect of LAF. Flow cytometry, wound healing, transwell assay, western blot, RT-PCR, and immunofluorescence analysis were carried out to investigate the pharmacological mechanism of LAF against TNBC.ResultsLAF significantly inhibited the growth of MDA-MB-231 tumors, with downregulated tumor level of vimentin and upregulated level of ZO-1. …”
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27483
Mortality and morbidity patterns in Yaoundé, Cameroon: an ICD-11 classification-based analysis
Published 2025-01-01“…Less than one-fifth (18.2%) of health care providers were able to understand data flow, correctly archived data (36.6%) and used electronic tools for data quality control (40.0%). …”
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27484
Anti-SARS-CoV-2 Antibody Screening in Healthcare Workers and Its Correlation with Clinical Presentation in Tertiary Care Hospital, Kathmandu, Nepal, from November 2020 to January 2...
Published 2022-01-01“…Anti-SARS-CoV-2 antibody screening was performed using lateral flow immunoassay. The data were analyzed using SPSS version 20. …”
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27485
Familial Adenomatous Polyposis and Desmoid Tumor Treated with Multivisceral Transplantation and Kidney Autotransplantation: Case Report and Literature Review
Published 2019-01-01“…Following the restoration of graft vascular flow, the patient’s right kidney was removed and the DT dissected ex vivo before autotransplantation into the right pelvic fossa. …”
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27486
Thermal optimization and exergy efficiency of two new parabolic solar collectors using response surface methodology
Published 2025-01-01“…This research examines the heat transfer performance of PTSC influence of different baffle types, including circular and trapezoidal shapes, integrated with turbulent nanofluid flow in the receiver tube. The inlet temperature of the heat transfer fluid was set at 120 °C, with the outlet temperature fluctuating between 250 °C to 450 °C. 3D computational fluid dynamics simulations using Ansys Fluent software and optimization process based on response surface methodology (RSM) using Design Expert analysis investigated entropy, thermal power, exergy efficiency, thermal efficiency and effective Prandtl number (Pr) for various solar panel configurations. …”
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27487
Liberties of the genome: insertions of mitochondrial DNA fragments into nuclear genome
Published 2024-09-01“…Of particular interest is the meaning of NUMTS in eukaryotic genome evolution. The constant flow of functionally inactive DNA sequences from mitochondria into the nucleus and its significance could be studied in view of the modern concepts of evolutionary theory suggesting non-adaptive complexity and the key role of stochastic processes in the formation of genomic structure.…”
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27488
The politics of digital sovereignty and the European Union’s legislation: navigating crises
Published 2025-02-01“…At the dawn of the digital age, technological innovation and the free flow of information promised unprecedented opportunities. …”
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27489
A 7-Amino Acid Peptide Mimic from Hepatitis C Virus Hypervariable Region 1 Inhibits Mouse Lung Th9 Cell Differentiation by Blocking CD81 Signaling during Allergic Lung Inflammation
Published 2020-01-01“…To address this, we studied wild-type mice treated with 7P and a control peptide in an in vivo mouse model of OVA-induced allergic inflammation and an in vitro cell model of Th9 differentiation, using flow cytometry, cytokine assays, and quantitative PCR. …”
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27490
Sorafenib enhanced the function of myeloid-derived suppressor cells in hepatocellular carcinoma by facilitating PPARα-mediated fatty acid oxidation
Published 2025-01-01“…These included subcutaneous tumor models, cell viability assays, flow cytometry, immunohistochemistry, and RNA sequencing. …”
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27491
Activated B Lymphocyte Inhibited the Osteoblastogenesis of Bone Mesenchymal Stem Cells by Notch Signaling
Published 2019-01-01“…Additionally, changes in lymphocytes (B lymphocyte, CD4+ and CD8+ T lymphocytes, and macrophages) in the bone marrow were analyzed by flow cytometry. The osteogenesis of BMSCs cocultured with normal and LPS-pretreated B lymphocytes was detected by BCIP/NBT and Alizarin red S staining. …”
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27492
Universities Graduates in the Far East Labour Market
Published 2019-12-01“…It was revealed that annual shortage of university-trained human resources for the Far East amounts to 13,000 taking into account both graduates’ employability and migration flows. Balance tables development such as “recruitment need – output” in terms of aggregated major groups/ fields of study contributed to carry out a qualitative analysis of the economy needs’ provision for university graduates in the Far Eastern regions. …”
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27493
KLF5 silencing restrains proliferation, invasion, migration and angiogenesis of gallbladder carcinoma cells by transcriptional regulation of PDGFA
Published 2024-12-01“…Cell apoptosis was evaluated using flow cytometry, and apoptosis-related proteins was examined by western blotting. …”
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27494
A new perspective on cardiovascular function and dysfunction during endurance exercise: identifying the primary cause of cardiovascular risk
Published 2024-04-01“…The rise in heart rate in response to thermal stress is a cardiovascular response that increases cardiac output and skin blood flow. The cardiovascular response during endurance exercise is a complex phenomenon potentially influenced by the involvement of nitric oxide in active thermoregulatory vasodilation. …”
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27495
Dental Pulp Mesenchymal Stem Cells Attenuate Limb Ischemia via Promoting Capillary Proliferation and Collateral Development in a Preclinical Model
Published 2021-01-01“…Among them, DP-MSCs and BM-MSCs produced much more impressive effects in restoring limb functions and promoting angiogenesis. The flow velocity restored to nearly 20% of the normal level at 3 weeks after treatments with DP-MSCs and BM-MSCs, and obvious capillary proliferation and collateral development could be observed. …”
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27496
A Fast and Validated HPLC Method for Simultaneous Determination of Dopamine, Dobutamine, Phentolamine, Furosemide, and Aminophylline in Infusion Samples and Injection Formulations
Published 2021-01-01“…Mobile phase A was buffer (50 mM KH2PO4) and mobile Phase B was acetonitrile at a flow rate of 1.0 mL/min. The column temperature was kept at 30°C, and the injection volume was 20 μL. …”
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27497
Comprehensive benefits evaluation of low impact development using scenario analysis and fuzzy decision approach
Published 2025-01-01“…The results show that LID measures, particularly combinations of sunken green spaces and permeable paving, offer significant reductions in runoff and peak flow, along with improved flood mitigation across multiple return periods. …”
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27498
Integrated Identification and Efficient Use of Biodiversity in Mountainous Regions
Published 2025-01-01“…The following issues were studied: hydrogeological research methods will help to identify the development zone of the intensive circulation aquifer (active water exchange) and the base of the development zone of the deep underground flow aquifer (impeded exchange) in the underground hydrosphere zones, and to assess their hydrodynamic and hydrothermal conditions and parameters. …”
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27499
Air-Entraining Effect on Rheological Properties of Cement-Based Mixtures
Published 2024-01-01“…Herschel–Buckley or modified Bingham models were used to approximate experimental flow curves and assess rheological parameters such as yield stress, plastic viscosity, and shear thinning/thickening index. …”
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27500
Evolution and trend of landslide research in India based on a decade long publication record
Published 2025-01-01“…The most common failure types reported were rock falls, debris flows, and rock slides, with rainfall identified as the primary landslide-triggering factor in 52 instances. …”
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