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  1. 27481

    Investigation of the Aquifer Protective Capacity and Groundwater Quality around Some Open Dumpsites in Sapele Delta State, Nigeria by Julius Otutu Oseji, James Chucks Egbai, Emmanuel Chukwuemeka Okolie, Etebefia Chris Ese

    Published 2018-01-01
    “…However, the aquifer shows good transmissivity, an indication that if it is contaminated, the contaminants will circulate the aquifer at a high rate. The groundwater flows in the northeast (NE) direction, thereby recharging river Ethiope. …”
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  2. 27482

    Anti-TNBC effects of Lappaol F by targeting epithelial-mesenchymal transition via regulation of GSK-3β/YAP/β-catenin and PI3K/AKT pathways by Qiqi Meng, Qiqi Meng, Zhiping Li, Xiaofeng He, Yuanhao Hu, Guiyun Wu, Jiawen Huang, Zhuohui Luo, Zhuohui Luo, Yingjie Hu, Xiaoling Shen

    Published 2025-02-01
    “…The present study aimed to reveal the potential mechanism of LAF against TNBC by in vivo and in vitro experiments.MethodsIn situ, transplantation-induced MDA-MB-231 solid tumor model in NCG mice and cultured MDA-MB-231 and Hs-578T cells were used to evaluate the anti-TNBC effect of LAF. Flow cytometry, wound healing, transwell assay, western blot, RT-PCR, and immunofluorescence analysis were carried out to investigate the pharmacological mechanism of LAF against TNBC.ResultsLAF significantly inhibited the growth of MDA-MB-231 tumors, with downregulated tumor level of vimentin and upregulated level of ZO-1. …”
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  3. 27483

    Mortality and morbidity patterns in Yaoundé, Cameroon: an ICD-11 classification-based analysis by Georges Nguefack-Tsague, Fabrice Zobel Lekeumo Cheuyem, Boris Edmond Noah, Valérie Ndobo-Koe, Adidja Amani, Léa Melataguia Mekontchou, Marie Ntep Gweth, Annick Collins Mfoulou Minso Assala, Marie Nicole Ngoufack, Pierre René Binyom

    Published 2025-01-01
    “…Less than one-fifth (18.2%) of health care providers were able to understand data flow, correctly archived data (36.6%) and used electronic tools for data quality control (40.0%). …”
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  4. 27484
  5. 27485

    Familial Adenomatous Polyposis and Desmoid Tumor Treated with Multivisceral Transplantation and Kidney Autotransplantation: Case Report and Literature Review by Libor Janousek, Robert Novotny, Michal Kudla, Martin Oliverius, Petr Wohl, Joan Minguet, Jan Martinek, Tomas Hucl, Jiri Fronek

    Published 2019-01-01
    “…Following the restoration of graft vascular flow, the patient’s right kidney was removed and the DT dissected ex vivo before autotransplantation into the right pelvic fossa. …”
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  6. 27486

    Thermal optimization and exergy efficiency of two new parabolic solar collectors using response surface methodology by Samaneh Baharloui, Mohammad Mohsen Peiravi, Mofid Gorji bandpy

    Published 2025-01-01
    “…This research examines the heat transfer performance of PTSC influence of different baffle types, including circular and trapezoidal shapes, integrated with turbulent nanofluid flow in the receiver tube. The inlet temperature of the heat transfer fluid was set at 120 °C, with the outlet temperature fluctuating between 250 °C to 450 °C. 3D computational fluid dynamics simulations using Ansys Fluent software and optimization process based on response surface methodology (RSM) using Design Expert analysis investigated entropy, thermal power, exergy efficiency, thermal efficiency and effective Prandtl number (Pr) for various solar panel configurations. …”
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  7. 27487

    Liberties of the genome: insertions of mitochondrial DNA fragments into nuclear genome by M. V. Golubenko, V. P. Puzyrev

    Published 2024-09-01
    “…Of particular interest is the meaning of NUMTS in eukaryotic genome evolution. The constant flow of functionally inactive DNA sequences from mitochondria into the nucleus and its significance could be studied in view of the modern concepts of evolutionary theory suggesting non-adaptive complexity and the key role of stochastic processes in the formation of genomic structure.…”
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  8. 27488

    The politics of digital sovereignty and the European Union’s legislation: navigating crises by Gábor Hulkó, János Kálmán, András Lapsánszky

    Published 2025-02-01
    “…At the dawn of the digital age, technological innovation and the free flow of information promised unprecedented opportunities. …”
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  9. 27489

    A 7-Amino Acid Peptide Mimic from Hepatitis C Virus Hypervariable Region 1 Inhibits Mouse Lung Th9 Cell Differentiation by Blocking CD81 Signaling during Allergic Lung Inflammation by Wanzhou Zhao, Conghao Tan, Xi Yu, Ruihe Yu, Qibing Mei, Yun Cheng

    Published 2020-01-01
    “…To address this, we studied wild-type mice treated with 7P and a control peptide in an in vivo mouse model of OVA-induced allergic inflammation and an in vitro cell model of Th9 differentiation, using flow cytometry, cytokine assays, and quantitative PCR. …”
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  10. 27490

    Sorafenib enhanced the function of myeloid-derived suppressor cells in hepatocellular carcinoma by facilitating PPARα-mediated fatty acid oxidation by Chunxiao Li, Liting Xiong, Yuhan Yang, Ping Jiang, Junjie Wang, Mengyuan Li, Shuhua Wei, Suqing Tian, Yuexuan Wang, Mi Zhang, Jie Tang

    Published 2025-01-01
    “…These included subcutaneous tumor models, cell viability assays, flow cytometry, immunohistochemistry, and RNA sequencing. …”
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  11. 27491

    Activated B Lymphocyte Inhibited the Osteoblastogenesis of Bone Mesenchymal Stem Cells by Notch Signaling by Mengxue Pan, Wei Hong, Ye Yao, Xiaoxue Gao, Yi Zhou, Guoxiang Fu, Yuanchuang Li, Qiang Guo, Xinxin Rao, Peiyuan Tang, Shengzhi Chen, Weifang Jin, Guoqiang Hua, Jianjun Gao, Xiaoya Xu

    Published 2019-01-01
    “…Additionally, changes in lymphocytes (B lymphocyte, CD4+ and CD8+ T lymphocytes, and macrophages) in the bone marrow were analyzed by flow cytometry. The osteogenesis of BMSCs cocultured with normal and LPS-pretreated B lymphocytes was detected by BCIP/NBT and Alizarin red S staining. …”
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  12. 27492

    Universities Graduates in the Far East Labour Market by V. A. Gurtov, I. S. Stepus, S. S. Shabaeva

    Published 2019-12-01
    “…It was revealed that annual shortage of university-trained human resources for the Far East amounts to 13,000 taking into account both graduates’ employability and migration flows. Balance tables development such as “recruitment need – output” in terms of aggregated major groups/ fields of study contributed to carry out a qualitative analysis of the economy needs’ provision for university graduates in the Far Eastern regions. …”
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  13. 27493

    KLF5 silencing restrains proliferation, invasion, migration and angiogenesis of gallbladder carcinoma cells by transcriptional regulation of PDGFA by Xiaowei Lu, Kui Hu, Dandan Zhang, Xuefeng Yin, Jifeng Nie, Kai Zhao

    Published 2024-12-01
    “…Cell apoptosis was evaluated using flow cytometry, and apoptosis-related proteins was examined by western blotting. …”
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  14. 27494

    A new perspective on cardiovascular function and dysfunction during endurance exercise: identifying the primary cause of cardiovascular risk by Amine Souissi, Ismail Dergaa, Samia Ernez Hajri, Karim Chamari, Helmi Ben Saad

    Published 2024-04-01
    “…The rise in heart rate in response to thermal stress is a cardiovascular response that increases cardiac output and skin blood flow. The cardiovascular response during endurance exercise is a complex phenomenon potentially influenced by the involvement of nitric oxide in active thermoregulatory vasodilation. …”
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  15. 27495

    Dental Pulp Mesenchymal Stem Cells Attenuate Limb Ischemia via Promoting Capillary Proliferation and Collateral Development in a Preclinical Model by Youfeng Li, Yuning Zhang, Hua Wang, Chengfeng Sun, Dongmei Liu, Hongying Liu, Jia He, Furong Chen, Weiting Wang, Xi Jiang, Chu-tse Wu, Yuefeng Yang

    Published 2021-01-01
    “…Among them, DP-MSCs and BM-MSCs produced much more impressive effects in restoring limb functions and promoting angiogenesis. The flow velocity restored to nearly 20% of the normal level at 3 weeks after treatments with DP-MSCs and BM-MSCs, and obvious capillary proliferation and collateral development could be observed. …”
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  16. 27496

    A Fast and Validated HPLC Method for Simultaneous Determination of Dopamine, Dobutamine, Phentolamine, Furosemide, and Aminophylline in Infusion Samples and Injection Formulations by Fuchao Chen, Baoxia Fang, Sicen Wang

    Published 2021-01-01
    “…Mobile phase A was buffer (50 mM KH2PO4) and mobile Phase B was acetonitrile at a flow rate of 1.0 mL/min. The column temperature was kept at 30°C, and the injection volume was 20 μL. …”
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  17. 27497

    Comprehensive benefits evaluation of low impact development using scenario analysis and fuzzy decision approach by Ting Ni, Xiaohong Zhang, Peng Leng, Mark Pelling, Jiuping Xu

    Published 2025-01-01
    “…The results show that LID measures, particularly combinations of sunken green spaces and permeable paving, offer significant reductions in runoff and peak flow, along with improved flood mitigation across multiple return periods. …”
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  18. 27498

    Integrated Identification and Efficient Use of Biodiversity in Mountainous Regions by Mehdiyeva A. M., Mahmudova Z. A., Rustamova D. F., Mansurova D., Juraeva G.

    Published 2025-01-01
    “…The following issues were studied: hydrogeological research methods will help to identify the development zone of the intensive circulation aquifer (active water exchange) and the base of the development zone of the deep underground flow aquifer (impeded exchange) in the underground hydrosphere zones, and to assess their hydrodynamic and hydrothermal conditions and parameters. …”
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  19. 27499

    Air-Entraining Effect on Rheological Properties of Cement-Based Mixtures by Aigerim Tolegenova, Gintautas Skripkiunas, Lyudmyla Rishko, Kenzhebek Akmalaiuly

    Published 2024-01-01
    “…Herschel–Buckley or modified Bingham models were used to approximate experimental flow curves and assess rheological parameters such as yield stress, plastic viscosity, and shear thinning/thickening index. …”
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  20. 27500

    Evolution and trend of landslide research in India based on a decade long publication record by Ashutosh Kainthola, Vishnu Himanshu Ratnam Pandey, Gaurav Kushwaha, Kumari Priya, P. K. Singh, T. N. Singh

    Published 2025-01-01
    “…The most common failure types reported were rock falls, debris flows, and rock slides, with rainfall identified as the primary landslide-triggering factor in 52 instances. …”
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