Quality of Life with Late-Onset Pompe Disease: Qualitative Interviews and General Public Utility Estimation in the United Kingdom by Lena Hubig, Anna-Katrine Sussex, Alasdair MacCulloch, Derralynn Hughes, Ryan Graham, Liz Morris, Syed Raza, Andrew J. Lloyd, Amanda Sowinski, Katy Gallop

“…The general public rated the health states consistently lower with increasing disease progression. There was greater uncertainty around utility estimates for the severe states, suggesting that participants found it harder to rate them. …”
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Intention to vaccinate against COVID-19 and adherence to non-pharmaceutical interventions against COVID-19 prior to the second wave of the pandemic in Uganda: a cross-sectional stu... by Ambrose Talisuna, Solome Okware, Rhoda K Wanyenze, Solomon Tsebeni Wafula, Innocent B Mugume, Benjamin Sensasi, Alexander Chimbaru, Richard Kabanda, Tabley Bakyaita, Jayne Byakika-Tusiime

“…Participants from the northern (4.0%, OR=0.28, 95% CI 0.12 to 0.92), western (5.1%, OR=0.30, 95% CI 0.14 to 0.65) and eastern regions (6.5%, OR=0.47, 95% CI 0.24 to 0.92), respectively, had lower odds of adhering to the COVID-19 guidelines than those from the central region (14.7%). …”
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Investigating uncertainty and parameter sensitivity in bedform analysis by using a Monte Carlo approach by J. Reich, A. Winterscheid

“…We applied the workflow to a test dataset from the Lower Rhine in Germany that was collected by the German Federal Waterways and Shipping Administration in February 2020. …”
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Ion homeostasis and coordinated salt tolerance mechanisms in a barley (Hordeum vulgare L.)doubled haploid line by Hongwei Xu, Hui Chen, Nigel G. Halford, RugenXu, Ting He, Bangwei Yang, Longhua Zhou, HuiminGuo, ChenghongLiu

“…Notably, the K+ efflux in DH20 was significantly lower while the Na+ and H+ efflux was significantly higher than those in Hua30 under salt stress in mesophyll cells. …”
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A Mobile App–Based Gratitude Intervention’s Effect on Mental Well-Being in University Students: Randomized Controlled Trial by Chloë Fuller, Silvia Marin-Dragu, Ravishankar Subramani Iyer, Sandra Melanie Meier

“…Participants in the subsample with at least moderate baseline symptomatology reported significantly lower symptoms of depression, anxiety, and stress postintervention (Cohen dPdPrPrP ConclusionsUniversity students experiencing moderate to severe distress can benefit from a gratitude intervention smartphone app to improve symptoms of depression, anxiety, and stress. …”
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YOLOX-SwinT algorithm improves the accuracy of AO/OTA classification of intertrochanteric fractures by orthopedic trauma surgeons by Xue-Si Liu, Rui Nie, Ao-Wen Duan, Li Yang, Xiang Li, Le-Tian Zhang, Guang-Kuo Guo, Qing-Shan Guo, Dong-Chu Zhao, Yang Li, He-Hua Zhang

“…However, orthopedic trauma surgeons have shown lower accuracy in ITF classification than expected. …”
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Behavioral factors associated with SARS-CoV-2 infection. Results from a web-based case-control survey in the Capital Region of Denmark by Mikkel Porsborg Andersen, Christian Torp-Pedersen, Helle Collatz Christensen, Ulrik Pedersen-Bjergaard, Thomas Alexander Gerds, Amalie Lykkemark Moeller, Birgitte Lindegaard, Mille Dybdal Cajar, Florence Chia Chin Tan, Mogens Karsboel Boisen, Sebastian Moretto Krog, Rúna Nolsoee, Peter Lommer Kristensen, Thomas Broe Christensen, Maria Elisabeth Lendorf

“…Most precautions, for example, using hand sanitizer (NC: 0.79; UC: 0.98), physical distancing (NC: 0.79; UC: 0.82) and avoiding handshakes (NC: 0.74; UC: 0.77), were associated with a lower rate of infection. Activities associated with many close contacts, especially indoors, increased rate of infection. …”
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EGCG improve meat quality, restore lipid metabolism disorder and regulate intestinal flora in high-fat fed broilers by Lujia Gao, Chen Liu, Jiaqi Wu, Ying Cui, Man Zhang, Chongpeng Bi, Anshan Shan, Xiujing Dou

“…Compared to high-fat diet-induced obese chickens, supplementation of EGCG significantly lowered hepatic fatty acid synthase (FAS) expression and lipid synthesis metabolites, while fatty acid decomposition enzymes showed no significant changes. …”
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Long-term effects of orthognathic surgery on masticatory function in individuals with cleft lip and palate: A prospective study by Patricia Martins Bueno, Paulo Alceu Kiemle Trindade, Laís Hollara Medeiros, Leide Vilma Fidélis da Silva, Ivy Kiemle Trindade-Suedam

“…Results: In the PRE-ORTHOG phase, the BF for the CLP group (x‾ RM + LM = 285 ± 141) was significantly lower compared to the CON group (x‾ RM + LM = 524 ± 202). …”
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Comparative analysis of deep learning and radiomic signatures for overall survival prediction in recurrent high-grade glioma treated with immunotherapy by Qi Wan, Clifford Lindsay, Chenxi Zhang, Jisoo Kim, Xin Chen, Jing Li, Raymond Y. Huang, David A. Reardon, Geoffrey S. Young, Lei Qin

“…The potential time-saving must be weighed against the lower interpretability of end-to-end black box modeling.…”
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Waning neutralizing antibodies through 180 days after homologous and heterologous boosters of inactivated COVID-19 vaccine by Zhifei Chen, Fangqin Xie, Hairong Zhang, Dong Li, Suhan Zhang, Mengping Zhang, Junrong Li, Jianfeng Xie, Lina Zhang, Xiuhui Yang, Dongjuan Zhang

“…By day 14 of post-boost, the ability to neutralize the Delta variant slightly diminished compared to the wild-type, whereas neutralizing antibodies against the Omicron variant exhibited a more pronounced decline, ranging from 10.78 to 19.88 times lower than those against the wild-type. Notably, heterologous boosting with the Convidecia vaccine maintained higher GMTs of neutralizing antibodies against both Delta and Omicron variants compared to the other boosters. …”
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Time-restricted feeding improves metabolic syndrome by activating thermogenesis in brown adipose tissue and reducing inflammatory markers by Yueling Gong, Yueling Gong, Honghui Zhang, Jiang Feng, Li Ying, Mengmeng Ji, Shiyin Wei, Shiyin Wei, Qiming Ma

“…TRF also increased thermogenesis by upregulating the expression of thermogenic genes (UCP1 and PGC-1α) in BAT, while lowering serum levels of pro-inflammatory cytokines IL-6 and TNF-α, though IL-1β levels remained unchanged.ConclusionThis study demonstrates that TRF can activate thermogenesis in brown adipose tissue and reduce inflammation maker, leading to an improvement in hepatic steatosis and a reduction in white adipose tissue accumulation. …”
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Effects of dietary selenium nanoparticles, selenomethionine and sodium selenite on growth performance, levels of thyroid hormones and antioxidant status of rainbow trout, Oncorhync... by Fardin Shaluei, Somayeh Hadadi, Shafigh Shafiei, Hossein Rahimi, Mehrdad Fattollahi

“…The level of malondialdehyde in the liver of fish fed the diet containing sodium selenite was significantly lower than the other experimental treatments (p<0.05). …”
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Feasibility, User Acceptance, and Outcomes of Using a Cancer Prehabilitation App for Exercise: Pilot Cohort Study by Fuquan Zhang, Deepali Bang, Christine Alejandro Visperas, Mon Hnin Tun, San San Tay

“…No significant differences in preoperative functional improvements were observed between app users and nonusers (6MWT: PPPPPPPP ConclusionsThis preliminary study demonstrates the acceptability, feasibility, and safety of Singapore’s first smartphone app for exercise prescription in cancer prehabilitation. Lower baseline functional outcome measures and a higher mean frailty score in the unprescribed group have implications for the selection process and patient participation. …”
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Kombinasi K-NN dan Gradient Boosted Trees untuk Klasifikasi Penerima Program Bantuan Sosial by Elly Firasari, Umi Khultsum, Monikka Nur Winnarto, Risnandar Risnandar

“…Gradient Boosted Trees produce lower accuracy percentage values than the K-NN method. …”
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NEW MID-SEASON SPRING BARLEY CULTIVAR OMSKY 101 by P. N. Nikolaev, O. A. Yusova, N. I. Aniskov, I. V. Safonova, J. V. Ryapolova

“…During the period of study, according to the maximum damage scores with various smut species, ‘Omsky 101’ showed low rates of susceptibility to false loose smut (3.5% on average) and covered smut (5.0%), which is lower than the reference and level with cv. ‘Omsky 100’. …”
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Phase I study of efineptakin alfa (NT-I7) for the treatment of Kaposi sarcoma by Leonard D’Amico, Martin Cheever, Steven P Fling, Anna Wright, Kathryn Lurain, Ramya Ramaswami, Irene Ekwede, Thomas S Uldrick, Robert Yarchoan, Judith C Kaiser, Angela Shaulov Kask, Manoj P Menon, Paul Couey, Eli Burnham, Allysson Angeldekao, Byung Ha Lee, Li-Lian Kwok, Chia-Ching Jackie Wang

“…Participants who experienced a response had HIV and lower CD4/CD8 ratio at baseline and throughout the study as compared with those who did not have KS response to NT-I7.Conclusions Preliminary data demonstrate safety and activity of IL-7 in patients with KS and activity specifically among individuals HIV-associated KS.Trial registration number NCT04893018.…”
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Pregnancy Complications and Outcomes in Obese Women with Gestational Diabetes by Gitana Ramonienė, Laura Malakauskienė, Eglė Savukynė, Laima Maleckienė, Greta Gruzdaitė

“…Neonates of these women more often had macrosomia (<i>p</i> < 0.001) and lower Apgar scores at 1 min (<i>p</i> = 0.024) and at 5 min (<i>p</i> = 0.024) compared to neonates of normal-weight women. …”
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Rumen DNA virome and its relationship with feed efficiency in dairy cows by Xiaohan Liu, Yifan Tang, Hongyi Chen, Jian-Xin Liu, Hui-Zeng Sun

“…Two pathways were proposed to explain how rumen viruses might modulate FE: (1) Lytic viruses could lyse beneficial host bacteria linked to favorable cattle phenotypes, such as vOTU1836 targeting Ruminococcaceae, resulting in diminished organic acid production and consequently lower FE; (2) AMG-mediated host metabolism modulation, exemplified by GT2 carried by vOTU0897, which may enhance Lachnospiraceae fermentation capacity, increasing organic acid production and thereby improving FE. …”
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Do Nonsuicidal Severely Depressed Individuals with Diabetes Profit from Internet-Based Guided Self-Help? Secondary Analyses of a Pragmatic Randomized Trial by Sandra Schlicker, Kiona K. Weisel, Claudia Buntrock, Matthias Berking, Stephanie Nobis, Dirk Lehr, Harald Baumeister, Frank J. Snoek, Heleen Riper, David D. Ebert

“…Major depressive disorder diagnosis at the baseline (pprf6=0.01), higher levels of depression (Beck Depression Inventory II; pprpo=0.00; pprf6=0.00), and lower HbA1c (pprpo=0.04) predicted changes in depressive symptoms. …”
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