Enhanced breast cancer cell targeting: RGD integrin ligand potentiates RWQWRWQWR’s cytotoxicity and inhibits migration by Andrea Barragán-Cárdenas, Daniel Castellar-Almonacid, Yerly Vargas-Casanova, Claudia Parra-Giraldo, Adriana Umaña-Pérez, Joel López-Meza, Zuly Rivera-Monroy, Javier García-Castañeda

“…Evaluation of mechanism associated to the cytotoxic effect were carried out by flow cytometry, RT-qPCR, wound healing, transwell and zymography. …”
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A probabilistic model-based approach to assess and minimize scaling in geothermal plants by Pejman Shoeibi Omrani, Jonah Poort, Eduardo G. D. Barros, Hidde de Zwart, Cintia Gonçalves Machado, Laura Wasch, Aris Twerda, Huub H. M. Rijnaarts, Shahab Shariat Torbaghan

“…The proposed modelling framework to demonstrate the optimization under uncertainty workflow consists of a multiphase flow solver coupled with a geochemistry model and an uncertainty quantification workflow to locally estimate the probability of precipitation potential, including its impact on the hydraulic efficiency of the geothermal plant by increasing the roughness and/or decreasing the diameter of the casings and pipelines. …”
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English Grammar Error Correction Algorithm Based on Classification Model by Shanchun Zhou, Wei Liu

“…The study results show that, with the continuous increase of training samples and the continuous progress of learning process, the proposed English grammar error correction algorithm based on the classification model will continue to increase its classification accuracy, further refine its recognition rules, and gradually improve correction efficiency, thereby reducing processing time, saving storage space, and streamlining processing flow. The study results of this paper provide a certain reference for the further research on English grammar error correction algorithm based on the classification model.…”
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Development of a high-order global dynamical core using the discontinuous Galerkin method for an atmospheric large-eddy simulation (LES) and proposal of test cases: SCALE-DG v0.8.0 by Y. Kawai, H. Tomita, H. Tomita

“…By conducting several tests with various polynomial (<span class="inline-formula"><i>p</i></span>) orders, the impact of the high-order DGM on the accuracy of the numerical simulations of atmospheric flows was investigated. To show high-order numerical convergence, a few modifications were made in the experimental setup of existing test cases. …”
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Investment climate assessment standards’ impact on the gross regional product growth of the Russian Federation subjects by L. I. Sergeyev, A. V. Samsonov

“…The revealed situation testifies to the uneven movement of financial flows in the Russian Federation: about 45.8%of the profit of organizations falls on Moscow and St. …”
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Design and Implementation of an Ethical AI-Based Teaching Assistant for IoT Security Education by Matilda Isaacs, Anwar Majeed, Karim Moussa, Dolapo Shodipo

“…Central to the project's success was a robust design phase that included carefully selecting AI algorithms, a modular and scalable architecture, an intuitive user interface, and efficient data flow mechanisms. Thorough testing and continuous improvements ensured seamless integration with existing educational technologies, enhancing learning and teaching experiences. …”
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Lung injury in myocardial infarction-associated cardiogenic shock supported by venoarterial extracorporeal membrane oxygenation: a scoping review by Akram M. Zaaqoq, Michael A. Mazzeffi, Melissa A. Vogelsong, Mark Roeser, Sung-Min Cho

“…We identified disruption of the pulmonary blood flow in patients with cardiogenic shock, with cardiac arrest being an extreme form of cardiogenic shock. …”
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Convenient estimation of oxytetracycline and polymyxin B by a novel high-performance liquid chromatography method: development and validation by Tanu Chaudhary, Balak Das Kurmi, Dilpreet Singh

“….), 5 μm], mobile phase consisting of aotearoa co-incidence network (ACN):water containing 0.5% (v/v) orthophosphoric acid (pH 3.5) in the ratio of 80:20 respectively. The flow rate was set at 0.9 mL/min and the column was maintained at room temperature. …”
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Measuring Passenger Car Equivalents (PCE) for Heavy Vehicle on Two Lane Highway Segments Operating Under Various Traffic Conditions by Pan Lu, Zijian Zheng, Denver Tolliver, Danguang Pan

“…Highway Capacity Manual 2010 (HCM 2010) used PCE values and percent of heavy vehicles to account the impacts on both highway planning and operation, however, PCE values in the latest version of HCM derived based on the steady and balanced two-lane-two-way (TLTW) traffic flows. The objective of the study is to identify PCE values for TLTW highway at various traffic volume with an emphasis on congestion conditions. …”
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Outer retina micro-inflammation is driven by T cell responses prior to retinal degeneration in early age-related macular degeneration by Lucas Stürzbecher, Lucas Stürzbecher, Lucas Stürzbecher, Lucas Stürzbecher, Hendrik Bartolomaeus, Hendrik Bartolomaeus, Hendrik Bartolomaeus, Hendrik Bartolomaeus, Theda U. P. Bartolomaeus, Theda U. P. Bartolomaeus, Theda U. P. Bartolomaeus, Theda U. P. Bartolomaeus, Sylvia Bolz, Andjela Sekulic, Marius Ueffing, Marius Ueffing, Simon J. Clark, Simon J. Clark, Simon J. Clark, Nadine Reichhart, Sergio Crespo-Garcia, Nicola Wilck, Nicola Wilck, Nicola Wilck, Nicola Wilck, Olaf Strauß

“…Dysfunction of the retinal pigment epithelium (RPE) is a unifying salient feature of the pathology and a primary end-point damage leading to complications such as geographic atrophy (GA), which represents the most common end-stage of AMD.MethodsHuman and murine ocular tissues were used for histological examinations. Furthermore, flow cytometry and gene expression analysis were used on ocular and splenic tissues of Cx3cr1GFP/GFP and C57BL/6J mice at 8 and 12 months of age to characterize the dynamics of local and systemic T cell populations.ResultsWe show the presence of memory T cells such as CD45RO+ cells in the choroid and retina of patients with AMD with a peak of abundance in early stages of AMD. …”
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Improving reading competence in aphasia with combined aerobic exercise and phono-motor treatment: Protocol for a randomized controlled trial. by Olga Boukrina, Elizabeth B Madden, Brian M Sandroff, Xiangqin Cui, Abubakar Yamin, Yekyung Kong, William W Graves

“…AET, known for its positive impact on cerebral blood flow (CBF) and oxygenation, is hypothesized to facilitate neuroplasticity when administered before PMT, an intensive therapy aimed at strengthening phonological processing. …”
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Eliminating Boundary Layer Separation on a Cylinder with Nonuniform Suction by James Ramsay, Mathieu Sellier, Wei Hua Ho

“…Boundary layer separation negatively influences the performance of aerospace vehicles, for example, by triggering static stall or reducing combustion engine efficiency. Developing effective flow control to delay or eliminate separation is therefore of real use to the field. …”
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Innovations and Structural Problems of Industry: Comparative Analysis of Azerbaijan’s Indicators with Turkish Republics by Gulshen Yuzbashiyeva, Samira Abasova, Israfil Yuzbashiyev

“…It is important to know at the expense of what resources structural changes will occur, what investments will be needed for this, and how much the existing structure will contribute to the flow of investment. A qualitatively new structural policy is advisable, based on an analysis of the changes that have been observed in recent years of economic development. …”
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Combined Experimental and CFD Investigation of the Parabolic Shaped Solar Collector Utilizing Nanofluid (CuO-H2O and SiO2-H2O) as a Working Fluid by Ketan Ajay, Lal Kundan

“…Nanofluids of SiO2-H2O (DI) and CuO-H2O (DI) of 0.01% volume concentration are used. Flow rates of 40 LPH and 80 LPH are used. ANSYS FLUENT 14.5 is used for carrying out CFD investigation. 3D temperature distribution of absorber tube is obtained using numerical investigation and the result is compared with the experimental one. …”
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Anticancer Potential of Fruit Extracts from Vatica diospyroides Symington Type SS and Their Effect on Program Cell Death of Cervical Cancer Cell Lines by Atchara Chothiphirat, Kesara Nittayaboon, Kanyanatt Kanokwiroon, Theera Srisawat, Raphatphorn Navakanitworakul

“…Distinctive morphological changes were observed in ACE-treated cervical cancer cells contributing to apoptosis action. Flow cytometry analysis with Annexin V-FITC and PI staining precisely indicated that ACE induced apoptosis in HeLa and SiHa cell lines in a dose-dependent manner. …”
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Combination of potassium oxonate with anti-PD-1 for the treatment of colorectal cancer by Yuanyuan Wang, Chenxi Hu, Tianpeng Du, Jiawen Li, Kaiyuan Hui, Xiaodong Jiang

“…We also tested the changes of TME through flow cytometry of spleen of mice in each group, as well as the IHC of cytokines.ResultsThe co-therapy of PO and anti-PD-1 showed admirable anti-tumor effect compared with the control group and the single drug groups. …”
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A Validated RP-HPLC Method for the Determination of Recombinant Human Insulin in Bulk and Pharmaceutical Dosage Form by B. A. Moussa, F. Farouk, H. M. E. Azzazy

“…The column temperature was 40 °C, the flow rate was 1 mL/min and detection was performed at 216 nm. …”
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Estimating Conveyance Efficiency and Maize Productivity of Traditional Irrigation Systems in Usa River Catchment, Tanzania by Humuri K. Haymale, Karoli N. Njau, Frederick C. Kahimba

“…The task involved measurement of irrigation water flows to determine the amount of water abstraction, inflow (head) and outflow (tail) between the canals to determine the conveyance efficiency of the main, secondary, and tertiary canals of the traditional irrigation systems. …”
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How coaching interventions impact learning organization culture, knowledge and customer experience performances: A case study comparing Thai car dealers from one US company by Sitthimet Solthong, Xavier Parisot, Vincent Ribiere

“…Among various benefits, coaching interventions can assist organizations with becoming learning organizations by developing a knowledge-sharing culture and strengthening knowledge flows. Nevertheless, there is insufficient empirical evidence supporting the positive impact of coaching interventions on both learning organization culture as defined in Watkins and Marsick’s model (1993) and knowledge and customer experience performances. …”
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Heart morphology and function evaluation by transthoracic echocardiography in six captive crested gibbons (Nomascus spp.) by Irène Vonfeld, Anaïs Nowakowski, Brice Lefaux, Benoît Quintard

“…Most functional parameters evaluated, like left ventricular ejection fraction (range, 49.3 to 72.4%), shortening fraction (SF; range, 18.9 to 34.5%), left atrium/aorta ratio (range, 0.8 to 1.2), and maximal velocity of aortic, pulmonic, and mitral flows had similar values as those described in gorillas, dogs, and humans. …”
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