Predictors and long-term patterns of medication adherence to glaucoma treatment in Denmark—an observational registry study of 30 100 Danish patients with glaucoma by Miriam Kolko, Rikke Faergemann Hansen, Louise G Dal, Emma Sabelström, Magnus Brandel, Andreas Hoiberg Bentsen, Anne Cathrine Falch-Joergensen

“…Adherence in the first year and in the first two years was associated with adherence in the fifth (ORfirst year: 4.55, 95% CI: 4.30 to 4.82/ORfirst two years: 6.47, 95% CI: 6.10 to 6.86) as with adherence in the 10th year with slightly lower estimates. Being medical adherent was related to higher costs related to glaucoma medication after 5 and 10 years comparing with poor adherence, whereas poor adherence was associated with a marked increase in long-term costs for hospital contacts.Conclusion Increasing age, female sex and low comorbidity score are correlated with better adherence to glaucoma treatment. …”
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Examining the Chemical and Optical Properties of Biomass-burning Aerosols and their Impact on Oxidative Potential by Suman Yadav, Taveen Singh Kapoor, Pradnya Vernekar, Harish C. Phuleria

“…The average (± SD) indoor PM2.5, OC, EC, BC, and WSOC during cooking using biomass fuels were 1025 ± 1001, 203 ± 196, 140 ± 133, 112 ± 61, and 130 ± 118 µg m−3, respectively, and the corresponding village outdoor levels were ~12.8 (p = 0.04), 4.9 (p = 0.14), 19.8 (p = 0.09), 23.6 (p = 0.01), and 8.1 (p = 0.12) folds (statistical significance of difference) lower, respectively. The volume normalized oxidative potential (DTTv) of PM from biomass cooking was 25.3 nmol DTT min−1 m−3, which was an order of magnitude higher redox active than rural ambient PM. …”
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Synergistic effects of allantoin and Achyranthes japonica-biochar profoundly alleviate lead toxicity during barley growth by Ghulam Murtaza, Najmaldin Ezaldin Hassan, Muhammad Usman, Gang Deng, Zeeshan Ahmed, Javed Iqbal, Mohamed S. Elshikh, Humaira Rizwana, Basharat Ali, Rashid Iqbal, Maximilian Lackner

“…The resistance towards Pb2+ was enhanced by biochar, allantoin, and their combined application, with lower Pb2+ concentrations in shoots (59.9 %, 40.1 %, and 49.8 %), roots (48.2 %, 24.1 %, and 58.3 %), and grains (60.2 %, 29.7 %, and 40.1 %) compared to solely Pb-stress, respectively. …”
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Habitual sleep duration, healthy eating, and digestive system cancer mortality by Diana A. Nôga, Elisa M. S. Meth, André P. Pacheco, Jonathan Cedernaes, Pei Xue, Christian Benedict

“…Additionally, a diet score ≥ 1 was linked to a lower cancer risk (0.72–0.91 (0.59–0.96)). Adjusting for smoking, type 2 diabetes, and body mass index (BMI) status eliminated the association between sleep duration and digestive cancer mortality. …”
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Associations between nutrient intake and osteoarthritis based on NHANES 1999 to 2018 cross sectional study by Xiaofeng Lv, Xinmin Deng, Rui Lai, Shanshan Liu, Zihao Zou, Xuechun Dai, Yalan Luo, Jian Luo, Ying Li

“…Compared with participants in the lowest quartile (Q1), those in the highest quartile (Q4) of dietary fiber, folic acid, and nicotinic acid intake had 27%, 28%, and 33% lower odds of having OA, respectively, after adjusting for potential confounding factors. …”
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Effect of TNF-α-Induced Sclerostin on Osteocytes during Orthodontic Tooth Movement by Fumitoshi Ohori, Hideki Kitaura, Aseel Marahleh, Akiko Kishikawa, Saika Ogawa, Jiawei Qi, Wei-Ren Shen, Takahiro Noguchi, Yasuhiko Nara, Itaru Mizoguchi

“…After 6 days of OTM, the percentage of sclerostin-positive osteocytes on the compression side of the first molar in TNFRsKO mice was lower than that in WT mice. In this study, TNF-α increased sclerostin expression in osteocytes, and sclerostin enhanced RANKL expression in osteocytes. …”
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The corneal biomechanical changes of phacoemulsification in cataract patients: A systematic review and meta-analysis. by Xinru Li, Xiaofeng Li, Lintong Tan, Hu Chen, Yuan Lai

“…The values of corneal hysteresis(CH) (MD = -0.43, 95% CI: [-0.62, -0.23]; P<0.05) and corneal resistance factor(CRF) (MD = -0.49, 95% CI: [-0.64, -0.33]; P<0.05) after phacoemulsification surgery were statistically lower than the control groups. While the values of IOPcc did not show statistically different (MD = -0.13, 95% CI: [-0.67, 0.41]; P = 0.64).…”
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Altering the intracellular trafficking of Necator americanus GST-1 antigen yields novel hookworm mRNA vaccine candidates. by Athos Silva De Oliveira, Leroy Versteeg, Neima Briggs, Rakesh Adhikari, Maria Jose Villar, JeAnna R Redd, Peter Hotez, Maria Elena Bottazzi, Jeroen Pollet

“…Although PM Na-GST-1 elicited one of highest titers of antigen-specific antibody and a diverse set of memory T-cell populations, it resulted in a lower ratio of neutralizing antibodies after IgG purification compared to the other vaccine candidates.…”
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The prognostic value of boost dose in residual cervical lymph nodes in nasopharyngeal carcinoma patients after intensity-modulated radiotherapy: a retrospective study by Mengting Xu, Liuling Wang, Jianming Ding, Yiying Xu, Zhaodong Fei

“…Results Patients with positive RCLN findings exhibited considerably lower 3-year relapse-free survival (RRFS), overall survival (OS), progression-free survival (PFS), and distant metastasis-free survival (DMFS) rates compared to those with negative findings (98.0% vs. 92.8%; 93.5% vs. 85.0%; 87.0% vs. 68.4%; 92.8% vs. 81.9%, all P < 0.001). …”
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Evaluation of Peripartum Hysterectomy in a Tertiary Care Unit and Its Effect on Patients’ Long-Term Physical and Mental Wellbeing: Quest Is Not Over When You Save the Life by P. D. M. Pathiraja, Asanka Jayawardane

“…Nine of the deliveries were elective lower-segment caesarean section and two were vaginal deliveries. …”
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Digitalization of public administration in Russia: risks, casuses, problems by L. A. Vasilenko, V. V. Zotov

“…Highlighting the weaknesses of modern public administration, the authors drew attention to such aspects of this problem as: 1) realization of “digitalization for the purpose of digitalization”; 2) deficiency of the required legal regulatory framework; 3) inefficiency of electronic document workflow, including problems caused by imperfections of the interface of reporting interactive forms, frequent change of the composition of indicators in reporting forms, desire of higher authorities to solve the problem of input of volume primary data at the expense of lower hierarchical levels; 4) absence of data analysis infrastructure, including due to imperfections of organization of interaction between agencies and incompatibility of information resources; 5) lack of data analysts and deficiency of necessary digital competences among state and municipal employees. …”
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Annual Zoledronic Acid for the Treatment of Osteoporosis: A Randomized Controlled Trial by Asif Hussain, Sushil Kumar Saini, Jaydeep Patel, Chandra Prakash Pal, Hemant Singh Chahar, Rohit Yadav

“…The efficacy of oral bisphosphonates is lower because of poor compliance. Annual treatment with zoledronic acid has been reported to improve outcomes. …”
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Relationship between klotho, neurotrophic factors (BDNF, NGF, GDNF) and cognitive functions in patients with bipolar disorder by Zeynep Çelebi, Esra Yazıcı, Derya Güzel Erdoğan, Onur Davutoglu, Ahmet Bulent Yazıcı

“…Results The klotho protein levels (0.12 ± 0.15 and 0.17 ± 0.16) and NGF levels (34.36 ± 41.99 and 48.54 ± 41.06) in the patient group were significantly lower than those in the control group (Z = -3.071, p = 0.002 and Z = -2.217, p = 0.027, respectively). …”
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Effects of family socioeconomic status on the self-expectations of children under grandparenting in China by QiXuan Hu

“…In comparison to families without grandparenting, those with grandparenting had significantly lower family SES, children’s self-expectations, parent-child communication, and parental marital status, with more students studying in non-elite schools. …”
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Soil Erosion Process Under the Combined Action of Water and Gravity on Red Soil Slope by ZHANG Xiaohan, MA Lan, YU Chong, WU Zhiwei, WANG Jie

“…Under the third rainfall, a small area of collapse occurred in the middle and lower part of the gravel soil, and the amount of gravity erosion was 6.08 × 103 cm3. …”
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A novel regional forecastable multiscalar standardized drought index (RFMSDI) for regional drought monitoring and assessment by Aamina Batool, Veysi Kartal, Zulfiqar Ali, Miklas Scholz, Farman Ali

“…The research findings include the following: 1) K-CGMD is a better fitting approach for standardizing RFMSDI and SPI based on reduced BIC values. 2) RFMSDI has superior performance over SPI based on the lower values of RMSE and MAE. 3) Both machine learning and classical methods reveal that RFMSDI outperforms SPI in predicting droughts. 4) SPI shows localized advantages with the ELM training set at 1- and 6-month time scales but RFMSDI offers a more comprehensive and consistent tool for drought prediction, especially when tested on unseen data. …”
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Determinants of nosocomial infections and emerging antibiotic resistance in the Intensive Care Unit: A prospective evidence-based study by Pranali Patil, Amol Muthal, Jignesh Shah, Asavari Raut

“…Stress ulcer prophylaxis (aOR 7.691, 95% CI 2.202-26.860, P=0.001), endotracheal intubation (aOR 3.251, 95% CI 1.251-8.420, P=0.015), Foley’s catheter (aOR 11.917, 95% CI 1.335-106.410, P=0.027), and ICU stay > 7 days (aOR 30.915, 95% CI 10.062-94.980, P=0.001) were statistically significant risk factors associated with nosocomial infection in ICU patients. …”
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Effect of dendritic cell vaccine on blood redox status in patients with cervical cancer by A. P. Menshenina, I. A. Goroshinskaya, E. M. Frantsiyants, T. I. Moiseenko, E. V. Verenikina, I. V. Kaplieva, L. A. Nemashkalova

“…Catalase activity, initially reduced by more than 40 %, remained 20–38 % lower than the norm at all stages of DCV. In this setting, hydrogen peroxide was probably inactivated by glutathione peroxidase whose activity was increased at all stages of treatment and decreased only when MDA was normalized after 7 DCVs.Conclusion. …”
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The mediating role of body surface area-adjusted basal metabolic rate: effects of low muscle mass and central obesity on cognitive impairment in Chinese patients with type 2 diabet... by Ya-Jie Zhai, Ya-Jie Zhai, Fang Li, Chen-Ying Lin, Chen-Ying Lin, Fan Wu, Hui-Na Qiu, Jing-Bo Li, Jing-Na Lin

“…Mediation analysis explored the role of BMR adjusted by body surface area (BMR/BSA) in CI risk.ResultsPatients with CI showed significantly lower BMR, BMR adjusted for height squared (BMR/Height²), BMR/BSA, appendicular skeletal muscle mass (ASM), and fat-free mass (FFM), alongside higher waist circumference (WC) and percentage of body fat. …”
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Curative Effect of Prebiotics/Probiotics-Assisted Ketogenic Diet on Children with Refractory Epilepsy by Lingying Su, Sai Li, Bo Sun

“…The incidence of adverse reactions in the combination group was lower than that in the KD group (13.64% vs 36.11%) (P<0.05). …”
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