Fragile Histidine Triad (FHIT) Suppresses Proliferation and Promotes Apoptosis in Cholangiocarcinoma Cells by Blocking PI3K-Akt Pathway by Qiang Huang, Zhen Liu, Fang Xie, Chenhai Liu, Feng Shao, Cheng-lin Zhu, Sanyuan Hu

“…The viability and apoptosis of QBC939 cells were then assessed using MTT assays and flow cytometry. Our results revealed that the expression of survivin and Bcl-2 was downregulated, and caspase 3 was upregulated, in cells overexpressing FHIT. …”
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Simulation of a Reverse Electrodialysis–Absorption Refrigeration Integration System for the Efficient Recovery of Low-Grade Waste Heat by Xi Wu, Linjing Yan, Xiaojing Zhu, Mingjun Liu

“…Based on this model, the authors simulated and analyzed the impact of various factors on system performance, including the heat source temperature (90 °C to 130 °C), concentrated solution concentration (3 mol∙L⁻¹ to 9 mol∙L⁻¹), dilute solution concentration (0.002 mol∙L⁻¹ to 0.5 mol∙L⁻¹), condensing temperature of the dilute solution (50 °C to 70 °C), solution temperature (30 °C to 60 °C) and flow rate (0.4 cm∙s⁻¹ to 1.3 cm∙s⁻¹) in the RED stacks, as well as the number of RED stacks. …”
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Voltage Stability Assessments and Their Improvement Using Optimal Placed Static Synchronous Compensator (STATCOM) by Tebeje Tesfaw Wondie, Teshome Goa Tella

“…In this study, the 400 kV, 230 kV, and 132 kV Ethiopian electric power networks are modeled using Power System Analysis Toolbox (PSAT), and the load flow analysis is carried out using MATLAB source code. …”
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Sources of Forecast Errors for Rainstorms in the South China Monsoon Region by Lin Lin, Chuhan Lu, Feifan Zhou

“…Based on this, we developed a new method (which we refer to as the “guide flow method”) to identify the sensitive area for rainstorm forecasts in the South China monsoon region and then examined the efficiency of the sensitive areas. …”
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Plasma from hypertensive pregnancy patients induce endothelial dysfunction even under atheroprotective shear stress by Sarah Viana-Mattioli, Miriam Helena Fonseca-Alaniz, Iguaracy Pinheiro-de-Sousa, Ricardo Rosa Junior, Moises Henrique Mastella, Ricardo de Carvalho Cavalli, Valeria Cristina Sandrim

“…Previous in vitro studies have not considered the impact of in vivo elements, such as the different patterns of blood flow, and laminar (LSS) vs. oscillatory (OSS) shear stress, on the development of ED. …”
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Spatial Analysis of Flood Hazard in Nirchay River Basin Using HEC-HMS Model and and fuzzy logic by fariba sfandyary darabad, mansour kheirizade, masoud rahimi

“…Rainfall conversion to runoff at the Nirchay River Basin controlled by slope and land-use.The most runoff height and peak flow in Nirchay River Basin are located in the upstream sub-basins. …”
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Spatial Differentiation and Elements Influencing Urban Resilience in the Middle Reaches of the Yangtze River under the COVID-19 Pandemic by Xin Hou, Qianli Ma, Xuan Wang

“…Thus, to upgrade the system cycle mechanism and augment the endogenous power for urban development, we need to focus more on the flow of innovative elements in central cities, the optimization of ecological and safe spatial patterns in Hunan and Hubei Provinces, and the innovation of sustainable supply chain in the entire region.…”
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Development and Validation of a Specific Stability Indicating High Performance Liquid Chromatographic Methods for Related Compounds and Assay of Solifenacin Succinate by B. V. Rami Reddy, B. Srinivasa Reddy, N. V. V. S. S. Raman, K. Subhash Reddy, C. Rambabu

“…The mobile phase-A contains a 0.01 M phosphate buffer pH: 3.5±0.05 with orthophosphoric acid (88%) and mobile phase-B contains a mixture of acetonitrile and water in the ratio of 90 : 10(v/v). The flow rate was 1.0 mL/minute, column temperature was kept at 35°C, and detection was monitored at 220 nm. …”
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Influence of Geometrical Design on Defect Formation of Commercial Al-Si-Cu-Mg Alloy Fabricated by High-Pressure Diecasting: Structural Observation and Simulation Validation by Warda Bahanan, Siti Fatimah, Dong-Ju Kim, I Putu Widiantara, Jee-Hyun Kang, Young Gun Ko

“…Because the associated work primarily relies on technical experience, it is necessary to perform the structural analysis of the HPDed component in comparison with simulation-based findings that forecast flow behavior, hence reducing trial and error for optimization. …”
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US Migration Policy Towards the States of the North American Continent by I. P. Tsapenko

“…Due to massive spontaneous flows of migrants who lack the required documents for entering, staying, and working in the country of destination, including asylum seekers, the region's countries face serious challenges aggravated by the pandemic. …”
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Toluene Conversion by Using Different Morphology MnO2 Catalyst by Huaijian Wang, Fangtong Liu, Wenting Yang, Chenglong Yu, Huanhuan Xiong, Jiaqi Li, Meijuan Lu

“…Next, their catalytic conversion test for toluene was carried out under the condition of toluene concentration of 500 ppm and gas flow rate of 200 mL min−1. The results showed that the crystal structure of nanotube and nanowire were α-MnO2, nanoflower was α-MnO2 phase and other crystalline, the nanocube was β-MnO2. …”
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A model of optimal dosing of antibiotic treatment in biofilm by Mudassar Imran, Hal L. Smith

“…The pharmacodynamics function is taken to be dependentboth on limiting nutrient and antibiotic concentration. Assumingthat flow rate of fluid compartment is large enough, we reduce thesix dimensional model to a three dimensional model. …”
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Toward Digital Transformation: Insights into Chinese Cross-Border E-Commerce SMEs During the COVID-19 Pandemic and the Post-Pandemic Era by Arthur William Fodouop Kouam

“…They should leverage technology, diversify their supply chain, adopt online marketing strategies, focus on customer service, optimize their cash flow, and explore new markets.…”
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Implementation and Comparison of High-Resolution Spatial Discretization Schemes for Solving Two-Fluid Seven-Equation Two-Pressure Model by Pan Wu, Fei Chao, Dan Wu, Jianqiang Shan, Junli Gou

“…The numerical results show that the high-resolution semi-implicit algorithm is robust in solving the two-pressure two-fluid two-phase flow model; Superbee scheme and Koren scheme give two highest levels of accuracy while Minmod scheme is the worst one among the eight TVD schemes.…”
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CRISPR screen reveals modifiers of rAAV production including known rAAV infection genes playing an unexpected role in vector production by Emily E. O’Driscoll, Sakshi Arora, Jonathan F. Lang, Beverly L. Davidson, Ophir Shalem

“…Specifically, we performed a CRISPR-based genome-wide knockout (KO) screen in human embryonic kidney (HEK) 293 cells using an antibody specific to intact AAV2 capsids coupled with flow cytometry to identify genes that modulate rAAV production. …”
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A mathematical model of mechanotransduction by Bradley J. Roth

“…Potential applications are discussed, such as predicting growth and remodeling in the diseased heart, analyzing stretch-induced arrhythmias, modeling shear forces in a vessel caused by blood flow, examining the role of mechanical forces in engineered sheets of tissue, studying differentiation in colonies of stem cells, and characterizing the response to localized forces applied to nanoparticles.…”
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Immersion in Complex Dynamical Systems with Ergodicity by Rômulo Damasclin Chaves dos Santos, Jorge Henrique de Oliveira Sales

“…Furthermore, the work introduces the Ergodic Theory of Turbulent Flow (ETTF), which probes the interplay between topological entropy and the ergodic properties of dynamic systems governed by the Navier-Stokes equations. …”
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Folate Receptor–Targeted Single-Photon Emission Computed Tomography/Computed Tomography to Detect Activated Macrophages in Atherosclerosis: Can It Distinguish Vulnerable from Stabl... by Leah C.J. Winkel, Harald C. Groen, Bibi S. van Thiel, Cristina Müller, Antonius F.W. van der Steen, Jolanda J. Wentzel, Marion de Jong, Kim Van der Heiden

“…We investigated the feasibility of a folate-based radiopharmaceutical ( 111 In-EC0800) with high-resolution animal single-photon emission computed tomography/computed tomography (SPECT/CT) to differentiate between stable and vulnerable atherosclerotic plaques in apolipoprotein E 7 mice in which we can induce plaques with the characteristics of stable and vulnerable plaques by placing a flow-modifying cast around the common carotid artery. …”
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Experimental Research on Performance of New Gas Drainage Borehole Sealing Material with High Fluidity by Xin Guo, Sheng Xue, Chunshan Zheng, Yaobin Li

“…To ensure the sealing effect of gas extraction borehole in underground coal mine and improve the concentration of gas extraction, a kind of high-flow sealing material which can be injected into the microcracks around borehole was developed. …”
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Baggley C. R., Read M. G. Investigation of a thermo-fluidic exchange pump in trilateral flash and organic Rankine cycles / trans. from Engl. M. A. Fedorova by M. A. Fedorova

“…One drawback of the TFC is the higher working fluid mass flow rate required. Depending on the scale of the system, this can potentially cause difficulties with pump selection. …”
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