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Desmoplasia in Pancreatic Cancer. Can We Fight It?
Published 2012-01-01“…Herein we discuss such new developments to fight the desmoplastic reaction, including inhibitors of the epidermal growth factor, fibroblast growth factor, the hedgehog pathway, as well as new molecular targets like CD40 agonist and its effects on T cells, extracellular matrix modifying enzymes such as LOXL2 inhibitor and novel tumour penetrating peptides for delivery of drugs.…”
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Mathematical Modeling, Analysis, and Optimal Control of Corruption Dynamics
Published 2020-01-01“…From the numerical simulation, it was found that the integrated control strategy must be taken to fight against corruption.…”
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Between giants and windmills: Lulismo in the presidential elections of 2018
Published 2023-09-01“…The methodology used combines the observation of the types of ads with the analysis of the French matrix discourse, based mainly on the contributions of Charaudeau and Orlandi. …”
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Réflexions sur l’appropriation du théâtre historique élisabéthain par la scène britannique contemporaine : usages de Macbeth dans Thirteenth Night de Howard Brenton (1981) et Dunsi...
Published 2022-01-01“…This article deals with how Shakespeare can be used as a matrix, either accommodating or problematic, to shape past or present events into a historical perspective on the contemporary stage, and looks at two plays that are explicit adaptations of Macbeth, Howard Breton’s Thirteenth Night (1981) and David Greig’s Dunsinane (2010). …”
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Nanoparticle Therapy Is a Promising Approach in the Management and Prevention of Many Diseases: Does It Help in Curing Alzheimer Disease?
Published 2020-01-01“…Treatment of brain diseases is always limited by the physiological nature of the highly selective blood-brain barrier (BBB) and the electrostatic charge of the nanoporous extracellular matrix. Nanomedical application provides a promising drug delivery revolution for the treatment of neurodegenerative diseases (NDDs). …”
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Current Treatment Regimens and Promising Molecular Therapies for Chronic Hepatobiliary Diseases
Published 2025-01-01“…Chronic hepatobiliary damage progressively leads to fibrosis, which may evolve into cirrhosis and/or hepatocellular carcinoma. The fight against the increasing incidence of liver-related morbidity and mortality is challenged by a lack of clinically validated early-stage biomarkers and the limited availability of effective anti-fibrotic therapies. …”
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An antibacterial, antioxidant and hemostatic hydrogel accelerates infectious wound healing
Published 2025-01-01“…The results confirmed its positive effects in fighting bacterial infection, reducing inflammation and promoting wound healing. …”
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Identification of most motivating resource for estimation of social hierarchy in water buffaloes
Published 2023-11-01“…The number of physical (fighting, bunting, pushing) and non-physical (threatening, avoiding) interactions were higher (p<0.01) for concentrate (439.4±13.49, 368.8±12.16) than green fodder (126.6±9.49, 147.8±90) and foggers (36.90±7.22, 83.5±6.61). …”
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