Falls and Fractures among Nursing Home Residents Treated with Pimavanserin versus Other Atypical Antipsychotics: Analysis of Medicare Beneficiaries with Parkinson’s Disease Psychos... by Krithika Rajagopalan, Nazia Rashid, Daksha Gopal, Dilesh Doshi

“…Results Of 7187 residents, 47.59% (n = 3420) were female and mean age was 78.8 (± 7.75) years. In total, 14% (n = 1005) were on PIM and 86% (n = 6182) were on other AAPs. …”
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Preventable hospitalizations through ED: does the number of hospital beds matter under the global budget in a single-payer system in Taiwan? by Hsueh-Fen Chen, Hsueh-Fen Chen, Hsueh-Fen Chen, Hui-Min Hsieh, Hui-Min Hsieh, Hui-Min Hsieh, Wei-Shan Chang

“…In contrast, other factors, such as female patients and the Charlson comorbidity index, were negatively associated with the likelihood of ED hospitalizations.ConclusionUnder hospital global budgeting with a floating-point value mechanism, increases in hospital beds likely motivate hospitals to admit ED patients with preventable and discretionary conditions. …”
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A qualitative study exploring the acceptability of the TEXTPAD telehealth and virtual supervised exercise intervention and trial for patients with peripheral arterial disease livin... by Maddey Patterson, MPH, Letitia Sermin-Reed, MSc, James Prentis, MBBS, Arathi Radhakrishnan, MBBS, Eileen Kaner, PhD, Sandip Nandhra, MBBS, Maisie Rowland, BSc, Gabriel Cucato, PhD, Mackenzie Fong, PhD

“…Fifteen patients were male and three were female. Overall, the TEXTPAD and walking programs were highly acceptable to and positively perceived by participants. …”
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Global leukemia burden and trends: a comprehensive analysis of temporal and spatial variations from 1990—2021 using GBD (Global Burden of Disease) data by Pengyu Huang, Jie Zhang

“…Males displayed higher leukemia incidence, mortality, and DALY rates compared to females. The oldest age groups, mainly those aged 95 and above, experienced the most significant changes, with the highest EAPC observed in this demographic. …”
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Association between diabetes mellitus and total hip arthroplasty outcomes: an observational study using the US National Inpatient Sample by Jasvinder A Singh, Sumanth Chandrupatla, Kranti Rumalla

“…Primary THA hospitlizations were analysed as the overall group and also stratified by the underlying primary diagnosis for THA.Outcome measures Outcome measures of interest were the length of hospital stay>the median, total hospital charges>the median, inpatient mortality, non-routine discharge, need for blood transfusion, prosthetic fracture, prosthetic dislocation and postprocedural infection, including periprosthetic joint infection, deep surgical site infection and postprocedural sepsis.Results Among 2 467 215 patients who underwent primary THA, the mean age was 68.7 years, 58.3% were female, 85.7% were white, 61.7% had Medicare payer and 20.4% had a Deyo-Charlson index (adjusted to exclude diabetes mellitus) of 2 or higher. 416 850 (17%) patients had diabetes. …”
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Nonlinear association between glycated hemoglobin levels and mortality in elderly patients with non-diabetic chronic kidney disease: a national health and nutrition examination sur... by Lihua Huang, Liuliu He, Qingfeng Zeng, Jinjing Huang, Xiaoyan Luo, Qiuming Zhong

“…Hazard ratios (HR) and 95% confidence intervals (CIs) for all-cause and CVD mortality were calculated using weighted Cox proportional hazards and restricted cubic spline models.ResultsAmong the 1,931 participants (mean [SE] age, 73.2 [0.2] years; 61.9% female), over a median follow-up period of 7.6 years, a total of 1,003 deaths were observed, including 412 from CVD. …”
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Conjunctival microbiota variations in a subset of middle-aged and elderly individuals from Beijing, China by Tian-Yao Zhao, Yu-Chen Wang, Ying-Juan Sun, Jun-Yue Wang, Xiao-Dan Jiang, Xue-Min Li, Ai-Hua Deng

“…Notably, an increased isolation rate of Corynebacterium and Micrococcus is detected, suggesting a possible change in the microbial balance that requires further investigation and attention from the ophthalmological community. Advanced age, female gender, MGD, diabetes, a recent history of infectious diseases, and inadequate mask-wearing habits are potentially significant factors associated with the conjunctival microbiota. …”
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Pre-injury frailty and clinical care trajectory of older adults with trauma injuries: A retrospective cohort analysis of A large level I US trauma center. by Oluwaseun Adeyemi, Corita Grudzen, Charles DiMaggio, Ian Wittman, Ana Velez-Rosborough, Mauricio Arcila-Mesa, Allison Cuthel, Helen Poracky, Polina Meyman, Joshua Chodosh

“…<h4>Results</h4>The mean (SD) age of the study population was 80 (8.9) years, and the population was predominantly female (64%) and non-Hispanic White (60%). Compared to those classified as robust, those categorized as frail had 2.5 (95% CI: 1.86-3.23), 3.1 (95% CI: 2.28-4.12), and 0.3 (95% CI: 0.23-0.42) times the adjusted odds of trauma team activation, inpatient admission, and ED discharge, respectively. …”
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Celastrol promotes DNA damage and apoptosis in uterine corpus endometrial carcinoma via promotion of KAT2B-mediated RBPJ acetylation and repression of MCM4 transcription by Lipeng Pei, Yan Zhu, Wenpeng Li, Bin Xu, Jingli Sun

“…Abstract Background Uterine corpus endometrial carcinoma (UCEC) is one of the most frequent female genital malignant tumors. Targeting DNA damage and cell apoptosis are regarded as effective ways for UCEC therapy. …”
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Oral pre-exposure prophylaxis implementation in South Africa: a case study of USAID-supported programs by Jerome Wendoh Milimu, Lauren Parmley, Mahlodi Matjeng, Mathata Madibane, Mandisi Mabika, Jacques Livingston, Joseph Lawrence, Orapeleng Motlhaoleng, Hasina Subedar, Rethabile Tsekoa, Zandile Mthembu

“…(vi) USAID-supported PrEP initiations have been highest among females of reproductive age in the general population and men who have sex with men among key populations, priority populations in South Africa. …”
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Interaction of genetics risk score and fatty acids quality indices on healthy and unhealthy obesity phenotype by Niloufar Rasaei, Seyedeh Fatemeh Fatemi, Fatemeh Gholami, Mahsa Samadi, Mohammad Keshavarz Mohammadian, Elnaz Daneshzad, Khadijeh Mirzaei

“…Therefore, in this study, we investigated how dietary fat quality indices with metabolically healthy obesity (MHO) or metabolically unhealthy obesity (MUO) based on the Karelis criterion interact with genetic susceptibility in Iranian female adults. Methods In the current cross-sectional study, 279 women with overweight or obesity participated. …”
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A Comparison of Resting Scapular Posture and the Davies Closed Kinetic Chain Upper Extremity Stability Test by John D Heick, Jenna Haggerty, Robert C Manske

“… # STUDY DESIGN Multicenter, single session descriptive cohort # METHODS Sixty-one healthy participants (33 males, 28 females; mean age 24.19±2.61) completed testing across two locations in one testing session. …”
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Evaluation of The Effect of Pre-Operative Informed Consent Form on Pre-Operative Anxiety by Sultan Zortul

“…Results: The mean age of participants was 45.5±14.66 years, with 31 (47%) female and 35 (53%) male participants. It was found that 31.8% of the participants did not experience anxiety (n=24), 36.4% had mild anxiety (n=13), 19.7% had moderate anxiety (n=8), and 12.1% had severe anxiety. …”
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Association between life's essential 8 and Parkinson's disease: a case–control study by Jiaxin Fan, Yanfeng Wang, Xingzhi Guo, Shuai Cao, Shuqin Zhan, Rui Li

“…Conclusions CVH, as delineated by LE8 metrics, was reversely associated with PD in the dose–response pattern, more pronounced in female compared to male. These findings highlight the potential of the LE8 metrics to guide targeted strategies for addressing gender-based CVH disparities, offering beneficial insights for the tertiary prevention of PD.…”
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Viral suppression and adherence in adolescents living with HIV in rural Tanzania. by Ezekiel Luoga, James Okuma, Lilian Moshi, George Sigalla, Dorcas Mnzava, Daniel H Paris, Tracy R Glass, Fiona Vanobberghen, Maja Weisser, Getrud Joseph Mollel, KIULARCO working group

“…Factors associated with viral suppression were having a CD4 cell count ≥500 cells/mm3 (adjusted Odds Ratio (aOR) 3.48; 95% CI 1.49-8.13) versus those with a CD4 cell count <500 cells/mm3, being on a dolutegravir-based regimen (aOR 12.6; 95% CI 2.50-68.7) versus those on a NNRTI based regimen. Female gender was associated with lower odds of having viral suppression (aOR 0.41; 95%CI 0.18-0.93). …”
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Automatic detection and multi-component segmentation of brain metastases in longitudinal MRI by Vincent Andrearczyk, Luis Schiappacasse, Daniel Abler, Marek Wodzinski, Andreas Hottinger, Matthieu Raccaud, Jean Bourhis, John O. Prior, Vincent Dunet, Adrien Depeurnge

“…The retrospective data includes 518 metastases in 184 contrast-enhanced T1-weighted MRIs originating from 49 patients (63% male, 37% female). 131 time-points (36 patients, 418 BMs) are used for cross-validation, the remaining 53 time-points (13 patients, 100 BMs) are used for testing. …”
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Association between healthy lifestyle choices and mental health among students: a cross sectional study by Yan Wang, Jiayu Zhang, Lihua Huang, Xiaonan Li, Yanyan Zhong

“…Multiple analysis revealed that personal characteristics including female (1.280[1.035—1.582]), obesity (2.015[1.278—3.175]), general or poor health status (1.738[1.380—2.188]; 4.265[1.125—16.165]), occasionally attending health knowledge lectures or paying attention to health books and information (1.376[1.055—1.795]), healthy lifestyle choices including occasionally or seldom eating breakfast (1.393[1.105—1.757]; 1.825[1.287—2.587]), occasionally or seldom getting enough sleep (2.800[2.179—3.597]; 3.544[2.209—5.685]), a poor or very poor irregular schedule (1.792[1.222—2.628]; 3.619[1.380—9.486]), seldom or no physical exercise (1.395[1.053—1.847]; 1.377[1.066—1.779]), and often smoking (3.320[1.281—8.604]) were identified as significant predictors of poor mental health. …”
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An exceptionally rare case of a diffuse midline glioma with concomitant H3.1 K27M and G34R mutations in the HIST1H3C (H3C3) gene by Zita Reisz, Rita Pereira, Smitha Nevis, Alan Mackay, Leena Bhaw, Yura Grabovska, Ross Laxton, Valeria Molinari, Anna Burford, Barnaby Clark, Cristina Bleil, Bassel Zebian, Erika Pace, Annette Weiser, Fernando Carceller, Lynley Marshall, Andrew King, Istvan Bodi, Safa Al-Sarraj, Chris Jones, Matthew Clarke

“…We report one such case of a 2-year-old female presenting with neurological symptoms; MRI imaging identified a brainstem lesion which was biopsied. …”
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Adherence and efficacy outcomes in young Australians with suicidal ideation using a self-management app and digital engagement strategy compared with a sham app: a three-arm random... by Michelle Torok, Lauren McGillivray, Daniel Z.Q. Gan, Jin Han, Sarah Hetrick, Quincy J.J. Wong

“…Findings: 692 participants were assigned (mean age: 19.9 [SD 2.5]; 70% female; intervention (combined): n–459, control: n–233). …”
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Prevalence and associated factors for poor mental health among young migrants in Sweden: a cross-sectional study by Sara Causevic, Anna Mia Ekström, Nicola Orsini, Anna Kagesten, Susanne Strömdahl, Mariano Salazar

“…Participants reporting poor mental health were more likely to be female (AOR:1.63, 95% CI:1.18–2.25), to have lived in Sweden more than three years (AOR:2.16, 95% CI:1.17–3.97), to engage in any sexual risk behaviour (AOR:1.99, 95% CI:1.25–3.17), and to live alone (AOR:1.95, 95% CI:1.25–3.03) or with friends they already knew (AOR:1.60, 95% CI:1.37–4.91). …”
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