Development of a Novel Prognostic Model for Lung Adenocarcinoma Utilizing Pyroptosis-Associated LncRNAs by Hong-Yan Bai, Tian-Tian Li, Li-Na Sun, Jing-Hong Zhang, Xiu-He Kang, Yi-Qing Qu

“…Lung cancer is a highly prevalent and fatal cancer that seriously threatens the safety of people in various regions around the world. …”
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Deep learning-based skin lesion analysis using hybrid ResUNet++ and modified AlexNet-Random Forest for enhanced segmentation and classification. by Saleem Mustafa, Arfan Jaffar, Muhammad Rashid, Sheeraz Akram, Sohail Masood Bhatti

“…Skin cancer is considered globally as the most fatal disease. Most likely all the patients who received wrong diagnosis and low-quality treatment die early. …”
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Plasma IL-6/IL-10 Ratio and IL-8, LDH, and HBDH Level Predict the Severity and the Risk of Death in AIDS Patients with Pneumocystis Pneumonia by Jia Sun, Junwei Su, Yirui Xie, Michael T. Yin, Ying Huang, Lijun Xu, Qihui Zhou, Biao Zhu

“…Plasma IL-8, LDH, and HBDH levels and IL-6/IL-10 ratio could be helpful for early evaluation of the severity and predicting fatal outcomes in AIDS PCP patients.…”
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Expression of some circulating microRNAs as predictive biomarkers for prognosis and treatment response in glioblastoma by Elham Ali, Marwa Adel Ahmed, May A. Shawki, Lobna R. Ezz El Arab, Mohamed K. Khalifa, Menha Swellam

“…Abstract Glioblastoma multiforme (GBM) is the most prevalent, treatment-resistant, and fatal form of brain malignancy. It is characterized by genetic heterogeneity, and an infiltrative nature, and GBM treatment is highly challenging. …”
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Novel metabolic prognostic score for predicting survival in patients with cancer by Jinyu Shi, Chenan Liu, Xin Zheng, Yue Chen, Heyang Zhang, Tong Liu, Qi Zhang, Li Deng, Hanping Shi

“…Abstract Cancer is a fatal disease with a high global prevalence and is associated with an increased incidence of metabolic disorders. …”
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Deep learning–assisted diagnosis of acute mesenteric ischemia based on CT angiography images by Lei Song, Xuesong Zhang, Jian Zhang, Jie Wu, Jinkai Wang, Feng Wang

“…The performance of the models was assessed using receiver operating characteristic (ROC) curves and decision curve analysis (DCA).ResultsAlbumin and International Normalized Ratio (INR) were associated with AMI by univariate and multivariate logistic regression (P < 0.05). …”
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Prediction of outcomes after chemoradiotherapy for cervical cancer by neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio by Jing Yu, Longzhang Huang, Ting Dong, Lihua Cao

“…Receiver operating characteristic (ROC) curves were plotted to analyse the optimal cut-off values of NLR and PLR for predicting the therapeutic effects of concurrent chemoradiotherapy. …”
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Development and validation of a deep learning-enhanced prediction model for the likelihood of pulmonary embolism by Yu Tian, Yu Tian, Jingjie Liu, Shan Wu, Yucong Zheng, Rongye Han, Qianhui Bao, Lei Li, Lei Li, Tao Yang

“…BackgroundPulmonary embolism (PE) is a common and potentially fatal condition. Timely and accurate risk assessment in patients with acute deep vein thrombosis (DVT) is crucial. …”
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Laboratory Risk Indicator for Necrotizing Fasciitis of the Oro-Cervical Region (LRINEC-OC): A Possible Diagnostic Tool for Emergencies of the Oro-Cervical Region by Masaru Ogawa, Satoshi Yokoo, Yu Takayama, Jun Kurihara, Takaya Makiguchi, Takahiro Shimizu

“…Delays in diagnosis and surgical treatment for OCNF led to a fatal prognosis, and the potential utility of the LRINEC-OC score for improving the prognosis was shown in this study.…”
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Long-Term Prospective Study of the Influence of Estrone Levels on Events in Postmenopausal Women with or at High Risk for Coronary Artery Disease by Antonio de Padua Mansur, Tereza Cristina B. F. Silva, Julio Yoshio Takada, Solange Desirée Avakian, Célia Maria C. Strunz, Luiz Antonio Machado César, José Mendes Aldrighi, José Antonio F. Ramires

“…Women were grouped according to their estrone levels (<15 and ≥15 pg/mL). Fatal events were recorded after 5.8±1.4 years of followup. …”
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The relationship between hypomagnesemia and ICU mortality in severe hemorrhagic stroke patients: an observational multicentre study on eICU database by Xinzhao Jiang, Faliang Gao, Zongjie Shi, Fang Liu, Wenyan Zhao, Guihong Gong

“…Abstract Background Hemorrhagic stroke is a potentially fatal condition with high mortality and morbidity. …”
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Clinical characteristics and associated factors of pediatric acute necrotizing encephalopathy: a retrospective study by Huiling Zhang, Yilong Wang, Qianyun Ding, Xuekun Li, Sheng Ye

“…Imaging examinations predominantly revealed symmetrical lesions in the thalamus. The fatal group displayed lower Glasgow Coma Scale (GCS) scores and severe complications. …”
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Altered CD73-Adenosine Signaling Linked to Infection in Patients undergoing hemodialysis by Xiang F, Zhang Z, Nie Y, Cao X, Li Y, Chen X, Gong S, Zou J, Teng J, Ding X, Shen B

“…Furthermore, they were associated with recurrent and fatal severe infections. Animal models demonstrated reduced CD73 mRNA transcript and adenosine receptor levels, along with decreased serum adenosine levels in CKD. …”
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Construction and evaluation of a triage assessment model for patients with acute non-traumatic chest pain: mixed retrospective and prospective observational study by Xuan Zhou, Gangren Jian, Yuefang He, Yating Huang, Jie Zhang, Shengfang Wang, Yunxian Wang, Ruofei Zheng

“…Decision curve analysis clarified that our model had higher net gains across the entire range of clinical thresholds. …”
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Genome-wide association study analysis of single nucleotide variants in L. infantum associated with IL-6 inflammatory response in visceral leishmaniasis by Amanda Miranda da Silva, Kátia Silene Sousa Carvalho, Caio Andrey Bezerra Januário, Raquel Gomes de Sena Carneiro Caldas, Bianka Lopes da Silva Paulino, Débora Cavalcante Braz, Dorcas Lamounier Costa, Gabriel da Luz Wallau, Wilson Jose da Silva Junior, Carlos Henrique Nery Costa

“…These findings demonstrate that IL-6 levels tended to be associated with the fatal outcome of VL and highlight 35 novel genetic variants that could serve as potential biomarkers for prognosis. …”
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Development and validation of an integrated model for the diagnosis of liver cirrhosis with portal vein thrombosis combined with endoscopic characters and blood biochemistry data:... by Jie Yang, Xu Zhang, Jia Chen, Xianghong Hou, Minghong Shi, Longlong Yin, Longchun Hua, Cheng Wang, Xiaolong Han, Shuyan Zhao, Guolan Kang, Ping Mai, Rui Jiang, Hongwei Tian

“…The predictive performance was evaluated by receiver operation curve (ROC), calibration curve, clinical decision analysis (DCA) and influence curve (CIC). …”
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Triglyceride‐glucose index trajectories predict adverse cardiovascular outcomes in elderly heart failure patients with Diabetes: A retrospective cohort study by Hong Liu, Jian Wang, Zhi Luo, Ding Jia, Shixing Feng, Zhufang Yang, Zeyu Wang

“…Methods This retrospective study included 1184 elderly HF (LVEF ≥50%) patients with diabetes admitted to our center between January 2015 and January 2020. …”
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The Diagnostic Value of Bile Acids and Amino Acids in Differentiating Acute Coronary Syndromes by Yu Q, Zhao F, Wang S, Jia X, Shen S, Zhao X, Li Y, Song J, Sun M, Liu X, Liu Z

“…., Ltd, Dalian, Liaoning, People’s Republic of China; 5Department of Laboratory Medicine, General Hospital of Fushun Mining Bureau of Liaoning Health Industry Group, Fushun, Liaoning, People’s Republic of China; 6Ultrasound Department, First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Zhining Liu, First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, 121001, People’s Republic of China, Tel +86 15941695215, Email liuzhiningfuyi@163.com Xin Liu, Huludao Central Hospital Teaching Base of Jinzhou Medical University, Huludao, Liaoning, 125001, People’s Republic of China, Tel +86 15941695215, Email lyy66112@163.comPurpose: Acute coronary syndrome (ACS), comprising unstable angina and acute myocardial infarction, is the most dangerous and fatal form of coronary heart disease. This study evaluates serum bile acids (BAs) and amino acids (AAs) as potential predictors of AMI in UA patients.Patients and Methods: A total of 72 Non-Coronary Artery Disease (NCAD) patients, 157 UA patients, and 79 AMI patients were analyzed. …”
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CoronaVac-induced antibodies that facilitate Fc-mediated neutrophil phagocytosis track with COVID-19 disease resolution by Chuang Li, Jie Yu, Rahma Issa, Lili Wang, Mingzhe Ning, Shengxia Yin, Jie Li, Chao Wu, Yuxin Chen

“…A predictive model was established incorporating ADNP activity and IgG titre, achieving an area under the curve (AUC) of 0.837. In the COVID-19 patient cohort, BA.5-specific ADCP and ADNP responses were significantly reduced in COVID-19 patients with fatal outcomes compared to milder outcomes. …”
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Krebs von den Lungen-6 surveillance in immune checkpoint inhibitor-induced pneumonitis by Isamu Okamoto, Kazuya Tsubouchi, Ryosuke Matsukane, Shoji Nakamura, Haruna Minami, Yasuto Yoneshima, Kojiro Hata, Sai Yasukochi, Kimitaka Suetsugu, Takeshi Hirota

“…Background The immune-related adverse event (irAE), pneumonitis, is a potentially fatal complication of immune checkpoint inhibitors (ICIs). …”
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