Genetics and pathophysiology of low-renin arterial hypertension by A. L. Markel

“…The review is devoted to the consideration of genetic determination and pathophysiology of one of the forms of hypertensive disease known as low-renin hypertension. At frst glance, the development of low-renin hypertension is “unnatural”, as renin, as a key enzyme of the renin-angiotensin system, which plays an important role in the development of hypertensive disease, is suppressed in low-renin hypertension. …”
Get full text

Road traffic crashes trends of severity and injuries in Osun state, Nigeria by Abayomi Afolayan, Adewole Oladele, Samson Olopade, Taiwo Adeoye

“…The dataset used is secondary data obtained from the Federal Road Safety Commission (FRSC), Osun State, Nigeria. …”
Get full text

RNAI-MEDIATED SILENCING OF MATRIX METALLOPROTEINASE 1 IN EPIDERMAL KERATINOCYTES INFLUENCES THE BIOLOGICAL EFFECTS OF INTERLEUKIN 17A by J. A. Mogulevtseva, A. V. Mezentsev, S. A. Bruskin

“…The obtained results demonstrated that MMP1 silencing in the cells treated with IL-17A resulted in downregulation of MMP9 and -12, FOSL1, CCNA2, IVL, KRT14 and -17 as well as upregulation of MMP2, CCND1 and LOR. …”
Get full text

On a novel lapping method for RB-SiC ceramic materials by integration of fixed-abrasive with even-sprayed micro-droplets by Yang Yu, Xuanping Wang, Xiaoguang Guo, Hang Gao

“…In this study, a novel fixed-abrasive spray suspension lapping (FSSL) process is proposed to achieve high-quality and efficient lapping of large-aperture RB-SiC mirrors, which can be integrated with computer controlled optical surfacing (CCOS) technology. …”
Get full text

Optimized design of a fault-tolerant 12-slot/10-pole six-phase surface permanent magnet motor with asymmetrical winding configuration for electric vehicles by Mahmoud Y. Mohamed, Mahmoud Fawzi, Ahmed Kalas, Ayman S. Abdel-Khalik, Shehab Ahmed, Ahmed Refaat

Subjects: Get full text

Galectin-1-Dependent Mitochondria Apoptosis Plays an Essential Role in the Potential Protein Targets of DBDCT-Induced Hepatotoxicity as Revealed by Quantitative Proteomic Analyses by Jiayu Song, Yuan Ren, Lihua Liu, Yixin Wang, Chuandao Shi, Xiaoqing Ji, Yunlan Li, Qingshan Li

“…Furthermore, it was demonstrated that DBDCT might promote ROS production, activate NF-κB p65, inhibit Ras and p-ERK1/2 expressions, increase the level of Gal-1, subsequently upregulate the expressions of Bax, p53, Fas, and FasL, and downregulate the expression of Bcl-2. …”
Get full text

FISCAL BALANCE AND SUSTAINABLE ECONOMIC DEVELOPMENT IN NIGERIA by ODILI OKWUCHUKWU, OKORO KELECHI OKORO, NWANNEDIYA FAITH OTI-IBIAM

“… This study analyzed the effects of fiscal balance on sustainable economic development in Nigeria from 1981 to 2022. Autoregressive Distributed Lag (ARDL) model was employed in estimating the variables. …”
Get full text

The role of ferroptosis and oxidative stress in cognitive deficits among chronic schizophrenia patients: a multicenter investigation by Zhenlei Peng, Qiyu Jia, Junxiong Mao, Shijie Jiang, Qi Ma, Xiao Luo, Zhiguo An, Anqi Huang, Chuang Ma, Qizhong Yi

“…Additionally, reduced GPX4 levels and increased ACSL4 and FE levels were significantly linked to negative symptoms and cognitive impairments. …”
Get full text

Establishment of a New Hyperglycemic Obesity Cardiac Dysfunction Mouse Model with Triacsin C by ZHAO Xiaona, WANG Peng, YE Maoqing, QU Xinkai

“…Immunofluorescence technology was used to analyze changes in CD31 and UCP1 in BAT. ACSL1 expression in myocardial tissue was tested by Western blotting.ResultsThe fasting blood glucose levels were (8.14±1.43) mmol/L in the Con group and (8.18±0.85) mmol/L in the TC group (P>0.05) , and the 2-hour postprandial blood glucose levels were (19.8±4.01) mmol/L in the Con group and (22.60±3.97) mmol/L in the TC group (P<0.05). …”
Get full text

miRNA-541-5p regulates myocardial ischemia–reperfusion injury by targeting ferroptosis by ZhiYu Zhao, BoXia Li, DianWei Cheng, YuFang Leng

“…HiSeq 2000 sequencing performed differential expression analysis of miRNAs. qRT-PCR and Western blots assessed the expression levels of GPX-4, ACSL-4, HO-1, TFR-1 and TFR-2. SPSS 21.0 software conducted statistical analysis. …”
Get full text

CHURCH SLAVONIC VERSION OF CAESAR BARONIUS ANNALES ECCLESIASTICI AND CHUDOV TRANSLATIONS FROM THE 17TH CENTURY: COMPARATIVE ANALYSIS OF VOCABULARY by Maria O. Novak

“…The article presents linguistic arguments in favour of a following hypothesis: a Church Slavonic translation of Caesar Baronius Annales Ecclesiastici (from the Polish adaptation made by Piotr Skarga), preserved in a 1689 manuscript (being kept in RSL, f. 256, no. 15), belonged to Moscow Chudov Monastery translators. …”
Get full text

Exploring Interconnections Among Environmental Degradation, Energy Consumption, Information and Communication Technology, and Total Factor Productivity in Iran by M. Abbasian

“…This study, the Autoregressive Distributed Lag (ARDL) model to evaluate the long-term and short-term dynamic, unit root tests and diagnostic tests CUSUM and CUSUMQ and Canonical Co-Integrating Regression (CCR) Dynamic least squares (DOLS), and fully modified least squares (FMOLS) have been used to validate the results of ADRL estimates. …”
Get full text

DIAGNÓSTICO DA APTIDÃO FÍSICA RELACIONADA À SAÚDE DE UNIVERSITÁRIOS by Maria Fátima Glaner, Cândido Simões Pires Neto, João Luiz Zinn

Get full text

Brezilya'da Yoksulluğu Azaltmada Kamu-Özel Sektör Enerji Yatırımlarının Rolü by Bekir Çelik

“…Bu amaca yönelik olarak gecikmesi dağıtılmış otoregresif sınır testi (ARDL) yaklaşımı uygulanmıştır. Uygulanan ARDL sınır testi sonucunda, Brezilya’da yoksulluk, kamu-özel enerji yatırımı, kişi başına düşen gelir ve CO2 emisyonu arasında uzun dönemli bir eş-bütünleşme ilişkisi olduğu doğrulanmıştır. …”
Get full text

Synthesis, characterization, and photophysical properties of novel 9‑phenyl-9-phosphafluorene oxide derivatives by Shuxian Qiu, Duan Dong, Jiahui Li, Huiting Wen, Jinpeng Li, Yu Yang, Shengxian Zhai, Xingyuan Gao

Subjects: Get full text

Floristic status of the Himalayan foothills in Haryana – vegetation composition, diversity and population structure by Dhiman Himanshi, Saharan Harikesh, Punia Harish, Jakhar Somveer

“…For this, different parameters like density, frequency, basal area, IVI, and various diversity indices were calculated by dividing the area into two altitudinal ranges, i.e. 400–600 m AMSL (AR_1) and 600–800 m AMSL (AR_2). The vegetation sampling was done by randomly selecting 30 plots in the selected area. …”
Get full text

Evaluation of Schneiderian First-rank Symptoms in Patients of Psychosis Attending a Tertiary Care Center from North India by Aditi Jain, Abbas Mehdi

Subjects: Get full text

Cecropin AD ameliorates pneumonia and intestinal injury in mice with mycoplasma pneumoniae by mediating gut microbiota by Bowen Li, Mingming Liu, Wenjing Du, Shuaidong Wang, Zekang Xu, Xiaoqian Zhang, Yang Zhang, Song Hua

“…Moreover, CAD treatment reversed the microbial dysbiosis and decreased the LPS levels induced by Mccp, thereby suppressing the activation of the TLR-4/NF-κB pathway and the Fas/FasL-caspase-8/-3 pathway. Consequently, this significantly mitigated the morphological and functional damage to the lungs and colons caused by Mccp. …”
Get full text

Silymarin: a promising modulator of apoptosis and survival signaling in cancer by Ujjawal Sharma, Praveen Kumar Sahni, Bunty Sharma, Madhu Gupta, Damandeep Kaur, Darin Mansor Mathkor, Shafiul Haque, Sabiha Khatoon, Hardeep Singh Tuli, Astha Mishra, Faraz Ahmad

“…Silymarin, a polyphenolic flavonoid with a variety of anti-cancerous properties, was isolated from the plant Silybum marianum. The present review centres on the function of silymarin in controlling important signalling pathways related to apoptosis and survival, such as the JAK/STAT pathway, PI3K/Akt/mTOR, Bcl-2/Bax, and Fas/FasL. …”
Get full text

A selective colorimetric chemosensor for detection of Cu(II) ions in aqueous samples by Ferretti, Cristián Alejandro, Gutierrez, Leandro Gabriel, Guntero, Vanina Alejandra, Noriega, Pablo Javier, Kneeteman, María Nelida

“…The proposed analytical method can be applied to $\mathrm{Cu}^{2+}$ quantification with a linear range covering from 5.0 to $315.8~{\mu }$M, and can be used to routinely analyze $\mathrm{Cu}^{2+}$ in environmental aqueous samples with satisfactory results.…”
Get full text