Showing 1 - 20 results of 2,462 for search 'FC Thun~', query time: 3.00s Refine Results
  1. 1

    Construction and characterization of chimeric FcγR T cells for universal T cell therapy by Juanjuan Zhao, Manling Chen, Xudong Li, Zhaoqi Chen, Wei Li, Rongqun Guo, Min Wang, Zhongxing Jiang, Yongping Song, Jianxiang Wang, Delong Liu

    Published 2025-01-01
    “…In the presence of rituximab (RTX), cytotoxicity of all three types of CFR T cells against CD20+ Raji-wt, K562-CD20+, and primary tumor cells was significantly higher than that of the mock T cells (P < 0.001). When herceptin was used, all three types of CFR T cells exhibited significant cytotoxicity against HER2+ cell lines of SK-BR-3, SK-OV-3, and HCC1954 (P < 0.001). …”
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    Role of Fcγ receptors in HER2-targeted breast cancer therapy by Hope S Rugo, Antonino Musolino, William J Gradishar, Jeffrey L Nordstrom, Edwin P Rock, Fernanda Arnaldez, Mark D Pegram

    Published 2022-01-01
    “…Margetuximab enhances Fc-dependent ADCC in vitro more potently than the combination of pertuzumab (another approved mAb directed against an alternate HER2 epitope) and trastuzumab. …”
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    Inhibition of Corneal Neovascularization by Subconjunctival Injection of Fc-Endostatin, a Novel Inhibitor of Angiogenesis by Junko Yoshida, Robert T. Wicks, Andrea I. Zambrano, Betty M. Tyler, Kashi Javaherian, Rachel Grossman, Yassine J. Daoud, Peter Gehlbach, Henry Brem, Walter J. Stark

    Published 2015-01-01
    “…Lower concentration FcE 2 exhibited better inhibition than FcE 20, consistent with previous FcE studies referencing a biphasic dose-response curve. …”
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    Fermentation characteristics of lactofermented cucumbers using an isolated Lactiplantibacillus plantarum NCHU–FC1 strain by Hsuan-Min Wang, Shwu-Jene Tsai, Jin-Yuarn Lin

    Published 2025-06-01
    “…The isolated LAB strain was identified as a Lactiplantibacillus (Lpb.) plantarum strain coding as Lpb. plantarum NCHU–FC1. The pH value was quickly lower than 4.6 (aka high-acid foods), while total nitrite contents were below the standard limit using 1 × 107 colony forming unit (CFU)/mL Lpb. plantarum NCHU–FC1 at 4 °C for 5 days. …”
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    Insight into the avidity–affinity relationship of the bivalent, pH-dependent interaction between IgG and FcRn by Johannes Reusch, Jan Terje Andersen, Ulrich Rant, Tilman Schlothauer

    Published 2024-12-01
    “…Furthermore, IgG1-YTE displayed a pH switch for the avidity enhancement factor at pH 6.2, reflecting strong receptor binding to both sides of the YTE-containing Fc, while avidity was abolished at pH 7.4. When compared with classical surface plasmon resonance (SPR) technology and complementary methods, the use of switchSENSE demonstrated superior capabilities in differentiating affinity from avidity within a single measurement. …”
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    Downmodulation of Vaccine-Induced Immunity and Protection against the Intracellular Bacterium Francisella tularensis by the Inhibitory Receptor FcγRIIB by Brian J. Franz, Ying Li, Constantine Bitsaktsis, Bibiana V. Iglesias, Giang Pham, Raju Sunagar, Sudeep Kumar, Edmund J. Gosselin

    Published 2015-01-01
    “…Fc gamma receptor IIB (FcγRIIB) is the only Fc gamma receptor (FcγR) which negatively regulates the immune response, when engaged by antigen- (Ag-) antibody (Ab) complexes. …”
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    Gender-Related Effects of Sex Steroids on Histamine Release and FcεRI Expression in Rat Peritoneal Mast Cells by Samira Muñoz-Cruz, Yolanda Mendoza-Rodríguez, Karen E. Nava-Castro, Lilián Yepez-Mulia, Jorge Morales-Montor

    Published 2015-01-01
    “…In addition to the well-characterized IgE/FcεRI-mediated degranulation, a variety of biological substances can induce MCs activation and release of their granule content. …”
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    Reducing neonatal Fc receptor binding enhances clearance and brain-to-blood ratio of TfR-delivered bispecific amyloid-β antibody by Eva Schlein, Ken G. Andersson, Tiffany Dallas, Stina Syvänen, Dag Sehlin

    Published 2024-12-01
    “…Bapi-Fab8D3 showed high brain uptake and the brain-to-blood ratio of its FcRn mutated form was significantly higher in AppNL-G-F mice than in WT mice 12 h after injection and increased further up to 168 h. …”
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    Polymeric Multivalent Fc Binding Peptides‐Fabricated Clinical Compounding Bispecific Antibody Potentiates Dual Immunotherapy Targeting PD1 and CTLA‐4 by Zongyu Liu, Hongyu Chu, Weidong Zhao, Chenguang Yang, Tongjun Liu, Na Shen, Zhaohui Tang

    Published 2025-01-01
    “…In this study, polymeric multivalent Fc‐binding peptides (PLG‐Fc‐III‐4C) are employed to fabricate a bispecific antibody (PD1/CTLA‐4 BsAb) to potentiate dual immunotherapy targeting PD1 and CTLA‐4. …”
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    Development and Evaluation of an In-House ELISA to Detect Anti-FcεR1α IgG Autoantibodies in Chronic Spontaneous Urticaria Patients by Chattip Sripatumtong, Tunsuda Tansit, Papapit Tuchinda, Duangjit Kanistanon, Kanokvalai Kulthanan, Yuttana Srinoulprasert

    Published 2022-01-01
    “…ELISA revealed that healthy people had a basal level of IgG anti-FcεR1α autoAbs, whereas their levels were significantly lower than autoAbs levels in CSU patients. …”
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    Local structural–functional coupling with counterfactual explanations for epilepsy prediction by Jiashuang Huang, Shaolong Wei, Zhen Gao, Shu Jiang, Mingliang Wang, Liang Sun, Weiping Ding, Daoqiang Zhang

    Published 2025-02-01
    “…Compared with previous methods, the proposed patterns quantify the relationship between SC and FC in terms of subgraphs rather than whole connections or single brain regions. …”
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    CD32B1, a versatile non-signaling antibody-binding scaffold for enhanced T cell adhesion to tumor stromal cognate antigens by Sara W. Feigelson, Tali Dadosh, Nehora Levi, Anita Sapoznikov, Hadas Weinstein-Marom, Hadas Weinstein-Marom, Dayana Blokon-Kogan, Dayana Blokon-Kogan, Yahel Avraham, Tamar Unger, Gideon Gross, Gideon Gross, Rony Dahan, Ronen Alon

    Published 2025-02-01
    “…This isoform contains an inhibitory ITIM motif within a cytoplasmic tail anchored to the cortical cytoskeleton. We thus generated a non-signaling CD32B1 mutant lacking the ITIM motif (termed ITIM-less CD32B1, or ILCD32B1) and successfully expressed it in human T cells which normally do not express this FcR. …”
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