Nitidine chloride inhibits the progression of hepatocellular carcinoma by suppressing IGF2BP3 and modulates metabolic pathways in an m6A-dependent manner by Dan-dan Xiong, Zhen-dong Chen, Jian-di Li, Yu-long Deng, Rong-quan He, Zhi-guang Huang, San-qi An, Yi-wu Dang, Gang Chen

“…Such insights provide a new direction in the study of NC’s anti-HCC mechanisms and offer novel perspectives for the treatment of HCC patients, focusing on both metabolic levels and m6A modification levels.…”
Get full text

Utilidad de la música en la preparación psicólogica de los deportistas / Usefulness of Music in the Psychological Preparation of Athletes by Francisco Enrique García-Ucha, Leopoldo Ferrer-Maldonado

“…It allows regulation of motivation and emotion, reduces perceived exertion, increases the amount of exercise performed, focuses the attention and improves recovery after exercise. …”
Get full text

Evaluasi Usability Aplikasi Elektronik-Kesehatan Ibu dan Anak (e-KIA) by Fitra Abdurrachman Bachtiar, Retno Indah Rokhmawati, Fajar Pradana, Intan Yusuf Habibie

“…The conducted usability testing is focus on Severity Ranking (SR), Ease of Fixing Ranking (EFR), and Problem Category. …”
Get full text

Pengaruh Ciri Temporal, Spasial, dan Frekuensi pada Klasifikasi Motor Imagery by Afin Muhammad Nurtsani, Muhammad Adib Syamlan, Agung Wahyu Setiawan

“…One of the development is focused on the classification of Imagery Motor (MI) based on EEG signals. …”
Get full text

The relationship between social support and depression among older adults with hypertension in urban communities: mediating effects of coping styles by Dan Li, Jin-Hua Jie, Hong Li, Xue-Mei Xia, Yilin Zhang, Yilin Zhang, Yan Yang, Yan Yang, Jianjun Xiang, Jianjun Xiang, Jianjun Xiang, Hai-Lin Zhuang

“…Interventions to reduce depression in this population should focus on enhancing social support (across objective, subjective, and utilization aspects) and promoting positive coping strategies, thus strengthening psychological resilience and improving overall health and quality of life for older adults with hypertension.…”
Get full text

An analysis of the Policy of Increasing the Salaries of Government Employees Based on the Framework of Kingdon's Multiple Streams (Case Study of Budget Law 1401) by Seyyed Mojtaba Shahraeini, Heidar Najafi, Seyyedamir Abbaszade, Mahdi Khosravi, Iman Akbari

“…These concerns are also a continuous focus for government employees. Consequently, the mechanism and amount of salary increases for government employees, in a fair and proportionate manner, remain a challenging aspect of the interactions between the government, parliament, and other stakeholders. …”
Get full text

Tata Kelola Teknologi Informasi Pada Sektor Publik: Penyelarasan Teknologi Informasi Dengan Visi Kepemimpinan (Studi Kasus: Kota Salatiga dan Kabupaten Bengkayang) by Andeka Rocky Tanaamah, Agustinus Fritz Wijaya, Sarah Ayu Maylinda

“…This study aims to: 1) identify leadership factors that focus on IT that influence the success or failure of IT governance implementation; (2) The extent to which the leadership vision can encourage the implementation of ITG in the Public Sector. …”
Get full text

Beneficiaries’ satisfaction with health insurance and associated factors in Sub-Saharan Africa: a systematic review and meta-analysis by Abubeker Alebachew Seid, Bizunesh Fantahun Kase, Abdu Hailu Shibeshi, Molla Getie Mehari, Abdulkerim Hassen Moloro

“…It is recommended that health insurance programmes in SSA focus on these factors to improve overall satisfaction among beneficiaries.PROSPERO registration number CRD42024496847.…”
Get full text

The Relationship Between Self-Efficacy, Aerobic Fitness, and Traditional Risk Factors for Musculoskeletal Injuries in Military Training: A Prospective Cohort Study by Brian R Kreisel, Kelly M Scott, Erin M Florkiewicz, Michael S Crowell, Jamie B Morris, Paige A McHenry, Timothy M Benedict

“…Previous research has focused on physical injury risk factors but has not prospectively examined psychological risk factors…”
Get full text

Penentuan Filterbank Wavelet Menggunakan Algoritma Mean Best Basis untuk Ekstraksi Ciri Sinyal Suara Ber-Noise by Abdurahim Abdurahim, Syahroni Hidayat

“…But so far the development has only been focused on clean speech signal. So, the aim of this study is designing WPCC for a noisy speech signal. …”
Get full text

Patient-Accessible Electronic Health Records and Information Practices in Mental Health Care Contexts: Scoping Review by Timothy Kariotis, Megan Prictor, Kathleen Gray, Shanton Chang

“…The impact of PAEHRs on information practices in mental health care contexts included the following: (1) they may change how HCPs document patient information, including a reduction in detail and a focus on information perceived by HCPs as objective rather than subjective; (2) they may negatively impact workflows due to changes in documentation practices and limited guidance for HCPs on how to use PAEHRs; and (3) they may contribute to improved communication between HCPs and patients, including constructive disagreements regarding what is documented in the health record. …”
Get full text

Determinants of fertility in timed artificial insemination programs in beef cattle: predictive ability and risk factors from almost 2 million data points by R.E.F. Assis, F. Baldi, L.B. Temp, R. Ungerfeld, M.F. de Sá Filho

“…Despite the influence of each factor, this study demonstrated the usefulness of analyzing big databases, allowing to determine effects that cannot be studied with experimental approaches, providing a complementary approach to decide where to focus future studies to enhance TAI pregnancy rates in beef cattle.…”
Get full text

Conflict-associated wounds and burns infected with GLASS pathogens in the Eastern Mediterranean Region: A systematic review by Amelia Wild, Clare Shortall, Omar Dewachi, Carine Naim, Alex Green, Sarah Hussain, Aula Abbara

“…This systematic review assesses literature focused on Global Antimicrobial Resistance Surveillance System (GLASS) Priority Pathogens causing infections in civilian wounds and burns in conflict-affected countries within the World Health Organisation’s Eastern Mediterranean Region Office (EMRO). …”
Get full text

Evidence adaptation and tailored implementation of family bereavement support in specialised palliative care: A multi-method study by Myrta Kohler, Qëndresa Thaqi, Silke Kuske, Torsten Schwalbach, Marco Riguzzi, Rahel Naef

“…Methods: Multi-method implementation research project combining community engagement strategies, qualitative contextual analysis, and theory-driven implementation design processes for integrating evidence-informed interventions in new contexts: First, evidence was identified and adapted through co-design staff workshops and service user consultations, following intervention adaptation guidelines. Next, focus group interviews were held to identify barriers and facilitators to implementation, informed by the Consolidated Framework for Implementation Research and analysed using qualitative content analysis. …”
Get full text

Summer Research Internship Curriculum to Promote Self-Efficacy, Researcher Identity, and Peer-to-Peer Learning: Retrospective Cohort Study by Yulia A Levites Strekalova, Rachel Liu-Galvin, Samuel Border, Sara Midence, Mishal Khan, Maya VanZanten, John Tomaszewski, Sanjay Jain, Pinaki Sarder

“…However, previous programs have focused predominantly on technical knowledge and skills, without integrating an academic enrichment curriculum that promotes professional development by improving students’ academic and research communication skills. …”
Get full text

Validity and reliability of the Manchester Oxford Foot Questionnaire (MOXFQ) in one-year postoperative ankle fracture patients—a validation study by Michael Quan Nguyen, Marjolein Memelink Iversen, Knut Harboe, Ingvild Dalen, Aksel Paulsen

“…Abstract Background Ankle fracture patients are a heterogenous group with differences in age, sex, fracture morphology, and treatment provided. With the increased focus on patient-centered treatment, patient-reported outcome measures (PROMs) are increasingly adopted by clinicians to facilitate best clinical practice. …”
Get full text

The Efficacy of Conversational AI in Rectifying the Theory-of-Mind and Autonomy Biases: Comparative Analysis by Marcin Rządeczka, Anna Sterna, Julia Stolińska, Paulina Kaczyńska, Marcin Moskalewicz

“…Future research should focus on enhancing affective response mechanisms and addressing ethical concerns such as bias mitigation and data privacy to ensure safe, effective AI-based mental health support.…”
Get full text

Evaluation of pulmonary tuberculosis disease burden in Shenyang, China, 2023 by Huijie Chen, Haiyan Bi, Peng Li, Zhixing Yang, Lihai Wen, Baijun Sun, Wei Sun

“…The predominant disease burden of PTB was attributed to YLLs, accounting for as much as 71.38%, indicating that PTB primarily results in premature mortality rather than disability. Therefore, the focus should be shifted towards early intervention to reduce transmission, especially for the aged males.…”
Get full text

Bioinspired activation strategies for Peano-HASEL artificial muscle. by Zhaozhen Liu, Harrison McAleese, Andrew Weightman, Glen Cooper

“…Specifically, activation strategy can, improve displacement control, contraction velocity and output force. Future work should focus on more complex artificial muscle arrangements and test activation strategies in practical experiments.…”
Get full text

Pendekatan Model ADDIE dan Framework MDA pada Gamifikasi Edukasi Pendidikan Seks Anak Usia Dini by Cynthia Hayat, Stefani Cancerita

“…The stages begin with a preprocessing of potential problems, analysis, design, development, implementation, and evaluation which will eventually become the final model after testing the user response to the developed application. While the focus elements on the MDA framework used include mechanics elements including; genre, goal, platform, rating, level, and concept art, dynamic elements include; storyline, game controls, challenges, and game rules, while aesthetics elements include; sensation, narrative, and submission. …”
Get full text