Neuroprotective Effect of Melatonin Loaded in Human Serum Albumin Nanoparticles Applied Subconjunctivally in a Retinal Degeneration Animal Model by Sofia Mickaela Martinez, Ayelen Inda, Maximiliano Nicolás Ríos, Carolina del Valle Bessone, Abril Bruera Bossio, Mario Eduardo Guido, José Domingo Luna Pinto, Daniel Alberto Allemandi, Daniela Alejandra Quinteros

“…Melatonin (Mel) is a potent antioxidant with neuroprotective properties; however, it faces limitations such as low solubility. This study proposes the use of human serum albumin nanoparticles (Np-HSA) to enhance the delivery of Mel to the posterior segment of the eye and evaluates its neuroprotective and anti-apoptotic effects on the retina. …”
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Dynamic rationing using agent-based modeling of the assembly process of equipment for nuclear power plants by I. A. Loskutov, D. A. Skvortsova, V. G. Iskandarova

“…The work is raised as an agent-based model designed to calculate the time spent on the assembly stage of the manufacturing process for manufacturing equipment for nuclear power plants. The article focuses on the need for development, states the justification for research and development of the field of nuclear energy, with repeated facts. …”
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„Wykazy czasopism MNiSW 2017 i 2019”, „ICI Journal Master List 2014–2017” a polskie czasopisma z historii nauki, historii, filozofii nauki oraz naukoznawstwa by Michał Kokowski

“…A comment has also been added to these results. The following facts were noted: a) the fact that there is a negative correlation between the journal’s rating in the “List of journals MNiSW 2019” and the journal’s ratings in the “ICI Journal Master List 2014–2017” for journals from the history and history of science; b) the fact that the presence of the journal in the DOAJ does not raise the ministerial rating of the journal; c) the fact that the evaluation of the journal in the Scopus database has not significantly affected the increase in the ministerial rating: the rating depends on the discipline and sub-discipline; d) the fact that journals from the ministerial program “Support for scientific journals 2019–2020” (WCN 2019–2020) and ERIH+ received 20 to 70 points; their ministerial ratings depend on discipline and sub-discipline. …”
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Mechanisms of the Effect of Starvation Duration on the Regulation of Feeding Rhythm and Metabolic Physiology of Cultured Large Yellow Croaker (<i>Larimichthys crocea</i>) by Xiaomeng Wang, Huang Liu, Chenglin Zhang, Chen Zhu, Huiyi Liu

“…However, deep-sea aquaculture also faces challenges such as typhoons and strong currents, which often lead to prolonged starvation in fish. …”
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Antioomycete Nanoformulation for Biocontrol of English Walnut Crown and Root Rot Caused by <i>Phytophthora cinnamomi</i> by Aldo Salinas, Iván Montenegro, Yusser Olguín, Natalia Riquelme, Diyanira Castillo-Novales, Alejandra Larach, Laureano Alvarado, Guillermo Bravo, Alejandro Madrid, Juan E. Álvaro, Ximena Besoain

“…In Chile and worldwide, walnut (<i>Juglans regia L.</i>) production faces significant losses due to crown and root rot caused by the phytopathogen <i>Phytophthora cinnamomi</i>. …”
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Identifying and Ranking the Causes of Delay Based on Production Strategies in Manufacturing Projects by Mohsen Rouzbahani, Mohammad Forozandeh

“…Purpose: Today, due to the increase in complexities and uncertainties faced by manufacturing organizations, the production of products faces planned/unplanned events that happen during the production life cycle. …”
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The Policy and Governance Observatory as a Facilitator of Smart and Evidence-based Governance by Atiye Yousefi, Mahdi Abdolhamid

“…Abstract The complex and dynamic environment and the multiplicity of actors have made the nature of decision-making and policy-making in political systems complex and challenging. In order to face the challenges in this space and make decisions based on the facts, it is necessary to monitor the public issues accurately and comprehensively and while benefiting from the ideas and opinions of the stakeholders in formulating and presenting policy solutions. …”
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A Chromosomal-level genome assembly and annotation of fat greenling (Hexagrammos otakii) by Li Li, Fawen Hu, Dong Liu, Xiaolong Wang, Jing Diao, Yijing Zhu, Fengxiang Gao, Ying Fan, Yuxia Jian, Xue Wang, Lei Pan, Wen Guo

“…However, the aquaculture industry faces challenges such as trait degradation, early sexual maturity, and disease susceptibility, necessitating advanced genomic interventions for sustainable cultivation. …”
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Development of an Integrated Model of Planning and Management in Free Zones with an Emphasis on Environmental Pressures by Mohammad Javad Amiri, Vahid Moghaddamzadeh, Gholamreza Nabi Bidhendi

“…Objective Nestled amidst the Arasbaran protected areas, Kiamaki wildlife sanctuary, and Dizmar protected area, the Aras Free Zone is a region teeming with environmental diversity and ecological significance. However, this region faces significant environmental challenges, primarily due to the overlooking of environmental principles in its economic development processes. …”
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Water, Sanitation and Hygiene in a Conflict Area: A Cross-Sectional Study in South Kordofan, Sudan by Rofida Asmally, Abdelmalik A. Imam, Abdullatif Eissa, Abubakr Saeed, Ahmed Mohamed, Eahaa Abdalla, Mariam Alazraa M. Esmaeel, Mariam Elbashir, Mohamed H. Elbadawi, Mohammed Omer, Raghad Eltayeb, Ranya Mohammed, Tibyan Abdalhamed, Tina Merghani

“…South Kordofan, a state in southern Sudan, faces WASH challenges due to conflict, geographical factors, and inadequate services, impacting over 600,000 residents. …”
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Biofloc technology significantly reshapes water microbiome and improves survival rates in Japanese eel (Anguilla japonica) by Jiho Yang, Hyunjun Choi, Jun Seong Park, Yehyeon Cha, Ju-Ae Hwang, Seung-Yoon Oh

“…ABSTRACT Global aquaculture production faces the challenge of biologically cycling nitrogenous waste. …”
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Assessing One Health integration in Somalia’s school curriculum for future pandemic preparedness by Ahmed Abdulkadir Hassan-Kadle, Aamir Muse Osman, Abas Mohamed Sharif

“…Abstract Background: The COVID-19 pandemic has highlighted the need for a holistic health approach, emphasizing the interconnectedness of human, animal, plant, and environmental health. Somalia faces significant health challenges, including drought, floods, disease outbreaks, and food and feed insecurity, underscoring the importance of integrating One Health (OH) concepts into its education system. …”
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Mapping the Dream: Designing Optimal E-Bike Routes in Valparaíso, Chile, Using a Multicriteria Analysis and an Experimental Study by Vicente Aprigliano, Catalina Toro, Gonzalo Rojas, Iván Bastías, Marcus Cardoso, Tálita Santos, Marcelino Aurélio Vieira da Silva, Emilio Bustos, Ualison Rébula de Oliveira, Sebastian Seriani

“…The city of Valparaíso, Chile, faces significant mobility challenges due to its steep slopes, complex urban infrastructure, and socioeconomic conditions. …”
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Comparative Analysis of Multiple Hydrological Models in Assessing Climate Change Impacts on the Mille Watershed, Awash Basin, Ethiopia by Asmare Belay Nigussie, Mihiretie Ayana, Dessalegn Worku Ayalew, Gerawork Feleke, Asnake Enawgaw Amognehegn, Anteneh Yayeh Adamu, Andualem Endalew, Tewodrose Desale Meselaw, Shankar Karuppannan

“…As industrial and economic growth intensifies, greenhouse gases are released into the atmosphere, leading to a shift in global warming and climate change patterns. The Mille watershed faces significant challenges such as flooding, drought, irrigation, and water supply scarcity, as well as health issues stemming from climate change within the community. …”
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Ethnobotanical survey of medicinal plants used in management of breast cancers in Qatar by Rasha.S.Abo El Alaa, Hend Al-Jaber, Fatima Al Zahraa Chokor, Abdullah A. Shaito, Layla Al-Mansoori

“…In Qatar, herbal medicine is widely used by the population, including breast cancer patients, yet preserving this knowledge faces significant challenges. This study aimed to document herbalists' ethnobotanical practices concerning breast cancer treatment in Qatar and corroborate any identified plant remedies' anticancer use with the literature. …”
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Peripheral blood cell counts as predictors of immune-related adverse events in cancer patients receiving immune checkpoint inhibitors: a systematic review and meta-analysis by Xinyu Zhang, Bei Zhang, Danfei Li, Yunchao Yang, Sen Lin, Ruiqi Zhao, Yijia Li, Lisheng Peng

“…Due to the variability in the frequency and severity of irAEs, clinical management faces a significant challenge in balancing antitumor efficacy with the risk of irAEs. …”
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Variations in Water Stress and Its Driving Factors in the Yellow River Basin by Haodong Lyu, Jianmin Qiao, Gonghuan Fang, Wenting Liang, Zidong Tang, Furong Lv, Qin Zhang, Zewei Qiu, Gengning Huang

“…As one of the most sensitive areas to climate change in China, the Yellow River Basin faces a significant water resource shortage, which severely restricts sustainable economic development in the region and has become the most prominent issue in the basin. …”
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Genetic Polymorphisms in RNF138, ABCA1 and ESRRG-GPATCH2 Genes and their Role in Insulin Resistance Risk among Normal BMI Individuals in Indian Population: A Case-control Study by Sabitha Thummala, Sarah Fathima, Nithya Kruthi, Junaid Ahmed Khan Ghori, Katherine Saikia, Vivek Belde, Balamurali Andiyakkal Rajendran, Rahul Ranganathan

“…Introduction: India, characterised as the “diabetes capital” of the world, faces a rapidly increasing diabetes crisis, with over 65 million cases diagnosed. …”
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Advancing health equity: evaluating AI translations of kidney donor information for Spanish speakers by Oscar A. Garcia Valencia, Charat Thongprayoon, Caroline C. Jadlowiec, Shennen A. Mao, Napat Leeaphorn, Pooja Budhiraja, Nadeen Khoury, Justin H. Pham, Iasmina M. Craici, Maria L. Gonzalez Suarez, Wisit Cheungpasitporn

“…BackgroundHealth equity and access to essential medical information remain significant challenges, especially for the Spanish-speaking Hispanic population, which faces barriers in accessing living kidney donation opportunities. …”
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Tensions within the British Conservative Party in the Context of Brexit by R. I. Blagoveshchenskii

“…The paper focuses on tensions within the ruling Conservative and Unionist Party of the United Kingdom of Great Britain and Northern Ireland over its membership in the European Union, which acquired a whole new dimension in the context of Brexit. …”
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