Collagen deposition in lung parenchyma driven by depletion of interstitial Lyve-1+ macrophages prevents cigarette smoke-induced emphysema and loss of airway function by Yinebeb Mezgebu Dagnachew, Yinebeb Mezgebu Dagnachew, Yinebeb Mezgebu Dagnachew, Hwee Ying Lim, Hwee Ying Lim, Liao Wupeng, Liao Wupeng, Sheau Yng Lim, Sheau Yng Lim, Sheng Jie Natalie Lim, Sheng Jie Natalie Lim, Chung Hwee Thiam, Chung Hwee Thiam, Shu Wen Tan, Shu Wen Tan, Joan Lau Joo Eng, Joan Lau Joo Eng, Dan Mei, Syaza Hazwany Mohammad Azhar, Wei Siong Ong, Qi Hui Caris Tan, Wai-Shiu Fred Wong, Wai-Shiu Fred Wong, Wai-Shiu Fred Wong, Veronique Angeli, Veronique Angeli

“…We found that deposition of collagen prior CS exposure protected these mice against destruction of alveoli (emphysema), and bronchi thickening and prevented loss of airway function.DiscussionThus, we uncover that interstitial Lyve-1+ macrophages regulate the composition, amount, and architecture of collagen network in the lungs at steady state and that such collagen remodeling functionally impacts the development of COPD. …”
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Loss of MTAP expression is strongly linked to homozygous 9p21 deletion, unfavorable tumor phenotype, and noninflamed microenvironment in urothelial bladder cancer by Natalia Gorbokon, Niklas Wößner, Viktoria Ahlburg, Henning Plage, Sebastian Hofbauer, Kira Furlano, Sarah Weinberger, Paul Giacomo Bruch, Simon Schallenberg, Florian Roßner, Sefer Elezkurtaj, Maximilian Lennartz, Niclas C Blessin, Andreas H Marx, Henrik Samtleben, Margit Fisch, Michael Rink, Marcin Slojewski, Krystian Kaczmarek, Thorsten Ecke, Tobias Klatte, Stefan Koch, Nico Adamini, Sarah Minner, Ronald Simon, Guido Sauter, Henrik Zecha, David Horst, Thorsten Schlomm, Lukas Bubendorf, Martina Kluth

“…Abstract Homozygous 9p21 deletions usually result in a complete loss of S‐methyl‐5′‐thioadenosine phosphorylase (MTAP) expression visualizable by immunohistochemistry (IHC). …”
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Case report of a Sertoli cell tumor with unique presentation including fevers, weight loss, and leukocytosis in a 13-year-old male by Austin G. Kazarian, Caleb Q. Ashbrook, Charles F. Timmons, Craig A. Peters, Bruce J. Schlomer

“…To our knowledge, this is the first reported case of a Sertoli cell tumor presenting with fever, leukocytosis, and weight loss.…”
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Corrigendum to “Melatonin Reverses the Loss of Stemness Induced by TNF-α in Human Bone Marrow Mesenchymal Stem Cells through Upregulation of YAP Expression” by Xudong Wang, Tongzhou Liang, Jincheng Qiu, Xianjian Qiu, Bo Gao, Wenjie Gao, Chengjie Lian, Taiqiu Chen, Yuanxin Zhu, Anjing Liang, Peiqiang Su, Yan Peng, Dongsheng Huang

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Auditory Phenotype of a Novel Missense Variant in the CEACAM16 Gene in a Large Russian Family With Autosomal Dominant Nonsyndromic Hearing Loss by Tatiana G. Markova, Natalia N. Alekseeva, Oxana P. Ryzhkova, Olga L. Shatokhina, Anna A. Orlova, Viktoriia V. Zabnenkova, Olga S. Groznova, Olesya V. Sagaydak, Svetlana S. Chibisova, Alexander V. Polyakov, George A. Tavartkiladze

“…BACKGROUND: Autosomal dominant hearing loss is represented by a large number of genetically determined forms. …”
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Efficacy of Prophylactic Cerclage in Women with a Single History of Mid-Trimester Pregnancy Loss with Painless Cervical Dilation: A Retrospective Cohort Study by Atsuko Tezuka, Hiroyuki Tsuda, Yumiko Ito, Tomoko Ando

“…Conclusions: History-indicated cerclage can be considered in women with a history of mid-trimester pregnancy loss who experience painless cervical dilation.…”
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Loss of H2A.Z Is Not Sufficient to Determine Transcriptional Activity of Snf2-Related CBP Activator Protein or p400 Complexes by Tamara A. Bowman, Madeline M. Wong, Linda K. Cox, Joseph J. Baldassare, John C. Chrivia

“…Our data indicates that nucleosome density at specific p21 or Sp1 promoter positions is not altered by the loss of either remodeling complex. However, knockdown of SRCAP or p400 reduces deposition of H2A.Z∼50% into all p21 and Sp1 promoter nucleosomes. …”
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Work-related temporary hearing loss and associated factors among textile industry workers in Amhara region, Ethiopia: a cross-sectional study by Giziew Abere, Eshetu Abera Worede, Atalay Tadele Yirdaw, Azanaw Asega Belay, Beletu Kinfe

“…The prevalence of work-related temporary hearing loss was 38.7% (95% CI 34.14% to 43.6%). Weaving department (AOR=6.6, 95% CI 3.06 to 14.3) and higher sound pressure level (>90 dBA) (AOR=7.9; 95% CI 2.6 to 23.7) were significantly associated with work-related temporary hearing loss among textile workers.Conclusions The prevalence of work-related temporary hearing loss among textile industry workers was high. …”
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Corrigendum to “Loss of SNHG4 Attenuated Spinal Nerve Ligation-Triggered Neuropathic Pain through Sponging miR-423-5p” by Xia Pan, Cheng Shen, Yayi Huang, Long Wang, Zhongyuan Xia

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Endothelial Cell Loss, Cumulative Dissipated Energy, and Surgically Induced Astigmatism in Sutureless Scleral Tunnel Phaco-Assisted Cataract Extraction in Advanced Cataracts by Marwa M. Salama, Sherif A. GamalElDin, Malak I. ElShazly

“…To evaluate sutureless scleral tunnel phaco-assisted cataract extraction in regards to the cumulative dissipated energy (CDE) used, the resulting endothelial cell loss (ECL), and the surgically induced astigmatism (SIA) in advanced cataracts. …”
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DR Loss-Free Dithering-Based Digital Background Linearity Calibration for SAR-Assisted Multi-Stage ADCs With Digital Input-Interference Cancellation by Lizhen Zhang, Bo Gao, Kun-Woo Park, Kent Edrian Lozada, Raymond Mabilangan, Hyeongjin Kim, Jianhui Wu, Seung-Tak Ryu

“…Unlike typical dithering-based calibration techniques in which signal dynamic range (DR) is unavoidably reduced, in this work, a small dither signal is injected into the input path by a simple switching scheme. The associated DR loss is avoided by the back-end redundancy. We also describe a capacitor-scanning dither method to accomplish simultaneous and independent identification of multiple bit weights. …”
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Weight loss-independent changes in human growth hormone during water-only fasting: a secondary evaluation of a randomized controlled trial by Benjamin D. Horne, Benjamin D. Horne, Benjamin D. Horne, Jeffrey L. Anderson, Jeffrey L. Anderson, Heidi T. May, Tami L. Bair, Viet T. Le, Viet T. Le, Leslie Iverson, Kirk U. Knowlton, Kirk U. Knowlton, Joseph B. Muhlestein, Joseph B. Muhlestein

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Loss of SMAD1 in acute myeloid leukemia with KMT2A::AFF1 and KMT2A::MLLT3 fusion genes by Lisa Dietsche, Kristin Stirm, Veronika Lysenko, Corina Schneidawind, Alexandar Tzankov, Anne Müller, Alexandre P. A. Theocharides

“…The loss of SMAD1 correlated with a markedly reduced amount of H3K4me3 levels at the SMAD1 promoter in tested cells with KMT2A::AFF1 and KMT2A::MLLT3. …”
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Blood loss in one-stage bilateral total knee arthroplasty: cruciate-retaining vs. posterior stabilized. A propensity score-matched analysis by Laoruengthana Artit, Tantimethanon Thanawat, Santisathaporn Nopparat, Inta-ngam Thisayapong, Pongpirul Krit, Rattanaprichavej Piti

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A diverse rotation of corn-soybean-winter wheat/double crop soybean with cereal rye after corn reduces tile nitrate loss by Lowell E. Gentry, Corey A. Mitchell, John M. Green, Carlos Guacho, Eric Miller, Dan Schaefer, Annette K. Vasquez, Zhongjie Yu

“…Increased crop rotational diversity may conserve nitrogen, support greater system resiliency, and reduce tile nitrate loss. This 9-year study compares tile nitrate loss under a 3-year rotation of corn-soybean-winter wheat/double crop soybean plus cereal rye after corn versus a conventionally managed 2-year corn-soybean rotation. …”
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Loss of histone H3K27me3 up-regulates SLC7A11 in diffuse gastric cancer cells by REN Yuanfeng, LIU Wenkang, CHU Zhaole

“…In gastric cancer tissues， compared to normal tissues， there was significant reprogramming of H3K27me3 modifications， characterized by a marked reduction in overall H3K27me3 signal intensity. The loss of 2 912 H3K27me3 signal peaks might lead to the up-regulation of 822 tumor-associated genes. …”
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Restes humains dans les fossés chasséens de Boury-en-Vexin (Oise) : Analyse liminaire de lésions traumatiques péri-mortem by Frédéric Boursier, Jean-Gabriel Pariat, Roger Martinez

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A Conservative Weight Loss Intervention Relieves Bowel Symptoms in Morbidly Obese Subjects with Irritable Bowel Syndrome: A Prospective Cohort Study by Martin Aasbrenn, Stian Lydersen, Per G. Farup

“…Irritable bowel syndrome (IBS) is common in subjects with morbid obesity; the effect of weight loss programs on bowel symptoms is largely unknown. …”
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Estimation of Wind Farm Losses Using a Jensen Model Based on Actual Wind Turbine Characteristics for an Offshore Wind Farm in the Baltic Sea by Ziemowit Malecha, Maciej Chorowski

“…The results demonstrate that as turbine spacing decreases, the velocity deficit behind the turbines increases, leading to significant reductions in AEP and higher energy losses. These effects are particularly pronounced for spacings of 5D and 3D, raising concerns about the economic feasibility of such wind farms. …”
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A Novel Numerical Algorithm for Optimal Sizing of a Photovoltaic/Wind/Diesel Generator/Battery Microgrid Using Loss of Load Probability Index by Hussein A. Kazem, Tamer Khatib

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